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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| Sep 1, 22 | Hering David | CEO | Purchase | $4.52 | 8.00K | $36.16K | 8.00K |
| Aug 17, 22 | M28 Capital Management LP | CTO | Purchase | $4.62 | 584.45K | $2.70M | 9.25M |
| Jul 5, 22 | Hering David | CEO | Purchase | -- | 2.00M | -- | 2.00M |
| Jun 22, 22 | MEANWELL CLIVE | CTO | Purchase | -- | 150.00K | -- | 150.00K |
| Jun 22, 22 | Berry Tamsin | CTO | Purchase | -- | 150.00K | -- | 150.00K |
| Jun 22, 22 | M28 Capital Management LP | CTO | Purchase | -- | 150.00K | -- | 150.00K |
| Jun 22, 22 | Berry Tamsin | CTO | Sale | -- | -- | -- | -- |
| Jun 22, 22 | Mayer Howard | CTO | Purchase | $3.09 | 75.00K | $231.75K | 75.00K |
| Jun 22, 22 | Mayer Howard | CTO | Purchase | -- | 75.00K | -- | 75.00K |
| Jun 22, 22 | WYZGA MICHAEL S | CTO | Purchase | -- | 75.00K | -- | 75.00K |
| Jun 22, 22 | Miller Redonda | CTO | Purchase | -- | 44.18K | -- | 44.18K |
| Jun 22, 22 | Heyman Tomas J. | CTO | Purchase | $3.09 | 75.00K | $231.75K | 75.00K |
| Jun 22, 22 | Heyman Tomas J. | CTO | Purchase | -- | 75.00K | -- | 75.00K |
| Jun 22, 22 | MCGUIRE TERRANCE | CTO | Purchase | $3.09 | 75.00K | $231.75K | 75.00K |
| Jun 22, 22 | MCGUIRE TERRANCE | CTO | Purchase | -- | 75.00K | -- | 75.00K |
| Mar 28, 22 | Cox Christopher T | other: See Explanation of Responses | Sale | -- | -- | -- | 679.82K |
| Mar 28, 22 | Elia Marc | -- | Sale | -- | -- | -- | 6.40M |
| Mar 3, 22 | Adimab, LLC | CTO | Sale | -- | 1.16M | -- | 26.69M |
| Mar 28, 22 | MEANWELL CLIVE | -- | Sale | -- | -- | -- | 1.20M |
| Mar 28, 22 | Cox Christopher T | -- | Sale | -- | -- | -- | 679.82K |
| Mar 28, 22 | Royan Ajay | CTO | Sale | -- | -- | -- | -- |
| Mar 28, 22 | MITHRIL II LP | 10 percent owner: | Sale | -- | -- | -- | -- |
| Mar 28, 22 | MEANWELL CLIVE | other: See Explanation of Responses. | Sale | -- | -- | -- | 1.20M |
| Mar 28, 22 | MCGUIRE TERRANCE | CTO | Sale | -- | -- | -- | -- |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 4.80M |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 3.12M |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 497.66K |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 60.81K |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 31.20K |
| Mar 28, 22 | Polaris Venture Partners V, L.P. | -- | Sale | -- | -- | -- | 21.37K |
| Jan 30, 22 | Hershberger Elham | Officer | Purchase | $6.78 | 175.00K | $1.19M | 175.00K |
| Jan 30, 22 | Hering David | COO | Purchase | $6.78 | 475.00K | $3.22M | 475.00K |
| Jan 30, 22 | Henderson Jane | CFO | Purchase | $6.78 | 175.00K | $1.19M | 175.00K |
| Jan 30, 22 | Gerngross Tillman U. | CEO | Purchase | $6.78 | 175.00K | $1.19M | 175.00K |
| Jan 30, 22 | Dabora Rebecca | Officer | Purchase | $6.78 | 175.00K | $1.19M | 175.00K |
| Jan 30, 22 | Connolly Lynn | Officer | Purchase | $6.78 | 175.00K | $1.19M | 175.00K |
| Jan 30, 22 | Andersen Jill | Officer | Purchase | $6.78 | 575.00K | $3.90M | 575.00K |
| Nov 19, 21 | Miller Redonda | CTO | Purchase | $20.07 | 62.60K | $1.26M | 62.60K |
| Nov 19, 21 | MARRAM ELLEN R | CTO | Purchase | $20.07 | 62.60K | $1.26M | 62.60K |
| Nov 19, 21 | Miller Redonda | CTO | Sale | -- | -- | -- | -- |
| Nov 19, 21 | MARRAM ELLEN R | CTO | Sale | -- | -- | -- | -- |
| Nov 1, 21 | Andersen Jill | Officer | Sale | -- | -- | -- | 2.20K |
| Nov 1, 21 | Andersen Jill | Officer | Sale | -- | -- | -- | 500 |
| Nov 1, 21 | Andersen Jill | Officer | Purchase | $30.65 | 514.86K | $15.78M | 514.86K |
| Nov 1, 21 | Andersen Jill | Officer | Sale | -- | -- | -- | -- |
| Aug 10, 21 | Royan Ajay | CTO | Purchase | $17.00 | 2.00M | $33.95M | 11.24M |
| Aug 10, 21 | Royan Ajay | CTO | Purchase | -- | 9.24M | -- | 9.24M |
| Aug 10, 21 | Royan Ajay | CTO | Sale | -- | 1.25M | -- | -- |
| Aug 10, 21 | Royan Ajay | CTO | Sale | -- | 176.30K | -- | -- |
| Aug 10, 21 | Royan Ajay | CTO | Sale | -- | 422.61K | -- | -- |
| Aug 10, 21 | MITHRIL II LP | 10 percent owner | Purchase | $17.00 | 2.00M | $33.95M | 11.24M |
| Aug 10, 21 | MITHRIL II LP | 10 percent owner | Purchase | -- | 9.24M | -- | 9.24M |
| Aug 10, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 422.61K | -- | -- |
| Aug 10, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 1.25M | -- | -- |
| Aug 10, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 176.30K | -- | -- |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 45.00K | $765.00K | 4.80M |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 4.76M | -- | 4.76M |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 267.77K | $4.55M | 3.12M |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 2.85M | -- | 2.85M |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 177.50K | $3.02M | 497.66K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 320.16K | -- | 320.16K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 5.22K | $88.72K | 60.81K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 55.59K | -- | 55.59K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 2.68K | $45.53K | 31.20K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 28.52K | -- | 28.52K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 1.83K | $31.18K | 21.37K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Purchase | -- | 19.54K | -- | 19.54K |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 44.08K | -- | -- |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 64.03K | -- | -- |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 32.02K | -- | -- |
| Aug 10, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 875.00K | -- | -- |
| Aug 10, 21 | Gerngross Tillman U. | CEO | Purchase | -- | 25.86M | -- | 27.85M |
| Aug 10, 21 | Gerngross Tillman U. | CEO | Sale | -- | 44.08K | -- | -- |
| Aug 10, 21 | Gerngross Tillman U. | CEO | Sale | -- | 128.06K | -- | -- |
| Aug 10, 21 | Gerngross Tillman U. | CEO | Sale | -- | 5.00M | -- | -- |
| Aug 10, 21 | Adimab, LLC | 10 percent owner | Purchase | -- | 25.86M | -- | 27.85M |
| Aug 10, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 128.06K | -- | -- |
| Aug 10, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 5.00M | -- | -- |
| Aug 10, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 44.08K | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 2.11M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 6.25M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 881.52K | -- | -- |
| Aug 10, 21 | Redmile Group, LLC | 10 percent owner | Purchase | $17.00 | 1.47M | $24.99M | 3.39M |
| Aug 10, 21 | Redmile Group, LLC | 10 percent owner | Purchase | -- | 1.92M | -- | 1.92M |
| Aug 10, 21 | Redmile Group, LLC | 10 percent owner | Sale | -- | 1.92M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 6.25M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 881.52K | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 2.11M | -- | -- |
| Aug 5, 21 | Mayer Howard | CTO | Purchase | $17.00 | 35.59K | $605.08K | 35.59K |
| Aug 5, 21 | MCGUIRE TERRANCE | CTO | Purchase | $17.00 | 35.59K | $605.08K | 35.59K |
| Aug 5, 21 | Royan Ajay | CTO | Purchase | $17.00 | 35.59K | $605.08K | 35.59K |
| Aug 5, 21 | Russo Rene | CTO | Purchase | $17.00 | 35.59K | $605.08K | 35.59K |
| Aug 5, 21 | WYZGA MICHAEL S | CTO | Purchase | $17.00 | 71.19K | $1.21M | 71.19K |
| Aug 5, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 12.39K | -- | -- |
| Aug 5, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 4.38M | -- | -- |
| Aug 5, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 220.38K | -- | -- |
| Aug 5, 21 | MCGUIRE TERRANCE | CTO | Sale | -- | 320.16K | -- | -- |
| Aug 5, 21 | WYZGA MICHAEL S | CTO | Sale | -- | -- | -- | -- |
| Aug 5, 21 | Shah Anand | CTO | Sale | $12.80 | 125.38K | $1.60M | -- |
| Aug 5, 21 | Russo Rene | CTO | Sale | -- | -- | -- | 1.99M |
| Aug 5, 21 | Royan Ajay | CTO | Sale | -- | 881.52K | -- | -- |
| Aug 5, 21 | Royan Ajay | CTO | Sale | -- | 2.11M | -- | -- |
| Aug 5, 21 | Royan Ajay | CTO | Sale | -- | 6.25M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 2.11M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 6.25M | -- | -- |
| Aug 5, 21 | MITHRIL II LP | 10 percent owner | Sale | -- | 881.52K | -- | -- |
| Aug 5, 21 | Mayer Howard | CTO | Sale | $4.61 | 215.15K | $991.84K | -- |
| Aug 5, 21 | Heyman Tomas J. | CTO | Sale | $12.80 | 125.38K | $1.60M | -- |
| Aug 5, 21 | Hershberger Elham | Officer | Sale | -- | -- | -- | 127.06K |
| Aug 5, 21 | Hershberger Elham | Officer | Sale | $4.61 | 254.12K | $1.17M | -- |
| Aug 5, 21 | Hershberger Elham | Officer | Sale | $10.14 | 284.94K | $2.89M | -- |
| Aug 5, 21 | Hershberger Elham | Officer | Sale | $12.80 | 192.56K | $2.46M | -- |
| Aug 5, 21 | Hershberger Elham | Officer | Sale | $0.78 | 254.12K | $198.21K | -- |
| Aug 5, 21 | Hering David | COO | Sale | $12.80 | 1.28M | $16.41M | -- |
| Aug 5, 21 | Henderson Jane | CFO | Sale | $4.61 | 1.20M | $5.55M | -- |
| Aug 5, 21 | Henderson Jane | CFO | Sale | $10.14 | 341.94K | $3.47M | -- |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | -- | -- | -- | 1.99M |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | $12.80 | 962.83K | $12.32M | -- |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | -- | 220.38K | -- | -- |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | -- | 25.00M | -- | -- |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | $10.14 | 3.42M | $34.67M | -- |
| Aug 5, 21 | Gerngross Tillman U. | CEO | Sale | -- | 640.32K | -- | -- |
| Aug 5, 21 | Dabora Rebecca | CTO | Sale | $0.78 | 330.88K | $258.09K | -- |
| Aug 5, 21 | Dabora Rebecca | CTO | Sale | $10.14 | 569.89K | $5.78M | -- |
| Aug 5, 21 | Connolly Lynn | Officer | Sale | $0.78 | 860.29K | $671.03K | -- |
| Aug 5, 21 | Connolly Lynn | Officer | Sale | $10.14 | 284.94K | $2.89M | -- |
| Aug 5, 21 | Adimab, LLC | 10 percent owner | Sale | -- | -- | -- | 1.99M |
| Aug 5, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 25.00M | -- | -- |
| Aug 5, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 640.32K | -- | -- |
| Aug 5, 21 | Adimab, LLC | 10 percent owner | Sale | -- | 220.38K | -- | -- |
| Aug 5, 21 | Redmile Group, LLC | 10 percent owner | Sale | -- | 1.92M | -- | -- |
| May 16, 12 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.15 | 31.76K | $100.05K | 794.00K |
| May 16, 12 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.15 | 954 | $3.01K | 26.14K |
| May 16, 12 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.15 | 520 | $1.64K | 15.55K |
| Mar 2, 12 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.38 | 2.88K | $9.74K | 2.88K |
| Mar 2, 12 | Southpaw Asset Management LP | 10 percent owner | Sale | $3.38 | 2.88K | $9.74K | -- |
| May 16, 12 | Southpaw Asset Management LP | 10 percent owner | Sale | $3.15 | 33.24K | $104.69K | -- |
| Jun 13, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 442 | $1.52K | 762.24K |
| Jun 8, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 1.05K | $3.64K | 761.80K |
| Jun 13, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 16 | $55.2 | 33.24K |
| Jun 8, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 38 | $131.1 | 33.22K |
| Jun 13, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 14 | $48.3 | 25.18K |
| Jun 8, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 34 | $117.3 | 25.17K |
| Jun 13, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 8 | $27.6 | 15.03K |
| Jun 8, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 20 | $69 | 15.02K |
| Jun 13, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 2 | $6.9 | 2.88K |
| Jun 8, 11 | Southpaw Asset Management LP | 10 percent owner | Purchase | $3.45 | 4 | $13.8 | 2.88K |
| Dec 31, 11 | Southpaw Asset Management LP | 10 percent owner: | Sale | -- | -- | -- | -- |
| Jun 7, 11 | Southpaw Asset Management LP | 10 percent owner | Sale | -- | -- | -- | 760.74K |
| Jun 7, 11 | Southpaw Asset Management LP | 10 percent owner | Sale | -- | -- | -- | 33.18K |
| Jun 7, 11 | Southpaw Asset Management LP | 10 percent owner | Sale | -- | -- | -- | 25.13K |
| Jun 7, 11 | Southpaw Asset Management LP | 10 percent owner | Sale | -- | -- | -- | 15.00K |
| Jun 7, 11 | Southpaw Asset Management LP | 10 percent owner | Sale | -- | -- | -- | 2.88K |
