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Today's biggest gainers and losers
| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| BNP Paribas Asset Management Holding S.A. | -- | Jun 30, 26 | -702.25K | -- |
| FMR LLC | -- | Jun 30, 26 | -6.85M | -- |
| PERCEPTIVE ADVISORS LLC | -- | Jun 30, 26 | -5.26M | -- |
| SILVERARC CAPITAL MANAGEMENT, LLC | -- | Jun 30, 26 | -466.35K | -- |
| J.Safra Asset Management Corp | -- | Jun 30, 26 | -397 | -- |
| MARSHALL WACE, LLP | -- | Jun 30, 26 | -168.18K | -- |
| NATIONAL BANK OF CANADA /FI/ | -- | Jun 30, 26 | -25 | -- |
| ROYCE & ASSOCIATES LP | -- | Jun 30, 26 | -278.06K | -- |
| BOOTHBAY FUND MANAGEMENT, LLC | -- | Jun 30, 26 | -39.66K | -- |
| Russell Investments Group, Ltd. | -- | Jun 30, 26 | -38.81K | -- |
| Headlands Technologies LLC | -- | Jun 30, 26 | -6.99K | -- |
| Holocene Advisors, LP | -- | Jun 30, 26 | -160.94K | -- |
| HRT FINANCIAL LP | -- | Jun 30, 26 | -116.99K | -- |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | -- | Jun 30, 26 | -8.93M | -- |
| Affinity Asset Advisors, LLC | -- | Jun 30, 26 | -1.40M | -- |
| FRED ALGER MANAGEMENT, LLC | -- | Jun 30, 26 | -168.17K | -- |
| GABELLI & Co INVESTMENT ADVISERS, INC. | -- | Jun 30, 26 | -9.40K | -- |
| Squarepoint Ops LLC | -- | Jun 30, 26 | -50.61K | -- |
| BRAIDWELL LP | -- | Jun 30, 26 | -1.99M | -- |
| SummitTX Capital, L.P. | -- | Jun 30, 26 | -206.85K | -- |
| ALPINE ASSOCIATES MANAGEMENT INC. | -- | Jun 30, 26 | -865.50K | -- |
| 5AM Venture Management, LLC | -- | Jun 30, 26 | -580.95K | -- |
| Eagle Health Investments LP | -- | Jun 30, 26 | -214.29K | -- |
| SBI Securities Co., Ltd. | -- | Jun 30, 26 | -30 | -- |
| Alyeska Investment Group, L.P. | -- | Jun 30, 26 | -320.43K | -- |
| FARALLON CAPITAL MANAGEMENT LLC | -- | Jun 30, 26 | -4.81M | -- |
| CITIGROUP INC | -- | Jun 30, 26 | -74.28K | -- |
| Buckland Partners Management Co LLC | -- | Jun 30, 26 | -30.00K | -- |
| Cormorant Asset Management, LP | -- | Jun 30, 26 | -1.05M | -- |
| GLAZER CAPITAL, LLC | -- | Jun 30, 26 | -325.00K | -- |
| RTW INVESTMENTS, LP | -- | Jun 30, 26 | -2.05M | -- |
| BALYASNY ASSET MANAGEMENT L.P. | -- | Jun 30, 26 | -852.83K | -- |
| TD ASSET MANAGEMENT INC | -- | Jun 30, 26 | -242.04K | -- |
| ADAR1 Capital Management, LLC | -- | Jun 30, 26 | -38.57K | -- |
| Pentwater Capital Management LP | -- | Jun 30, 26 | -8.17M | -- |
| SJS Investment Consulting Inc. | -- | Jun 30, 26 | -22 | -- |
| WELLS FARGO & COMPANY/MN | -- | Jun 30, 26 | -6.00K | -- |
| Coastal Bridge Advisors, LLC | -- | Jun 30, 26 | -13.10K | -- |
| TORONTO DOMINION BANK | -- | Jun 30, 26 | -654.85K | -- |
| GABELLI FUNDS LLC | -- | Jun 30, 26 | -17.60K | -- |
| JONES FINANCIAL COMPANIES LLLP | -- | Jun 30, 26 | -277 | -- |
| Rangeley Capital, LLC | -- | Jun 30, 26 | -9.00K | -- |
| FEDERATED HERMES, INC. | -- | Jun 30, 26 | -2.05M | -- |
| Bayforest Capital Ltd | -- | Jun 30, 26 | -1.95K | -- |
| TORNO CAPITAL, LLC | -- | Jun 30, 26 | -20.00K | -- |
| TCG Crossover Management, LLC | -- | Jun 30, 26 | -4.29M | -- |
| Deep Track Capital, LP | -- | Jun 30, 26 | -3.16M | -- |
| Bank of New York Mellon Corp | -- | Jun 30, 26 | -8.30K | -- |
| D. E. Shaw & Co., Inc. | -- | Jun 30, 26 | -643.81K | -- |
| Weiss Asset Management LP | -- | Jun 30, 26 | -510.41K | -- |
| ADIRONDACK TRUST CO | -- | Jun 30, 26 | -925 | -- |
| Tower Research Capital LLC (TRC) | -- | Jun 30, 26 | -41 | -- |
| First Light Asset Management, LLC | -- | Jun 30, 26 | -1.56M | -- |
| GOLDMAN SACHS GROUP INC | -- | Jun 30, 26 | -1.14M | -- |
| Basecamp Wealth Advisors LLC | -- | Jun 30, 26 | -128 | -- |
| VOYA INVESTMENT MANAGEMENT LLC | -- | Jun 30, 26 | -29.67K | -- |
| TWO SIGMA INVESTMENTS, LP | -- | Jun 30, 26 | -59.84K | -- |
| Crossmark Global Holdings, Inc. | -- | Jun 30, 26 | -19.44K | -- |
| CSS LLC/IL | -- | Jun 30, 26 | -17.00K | -- |
| Avoro Capital Advisors LLC | -- | Jun 30, 26 | -11.43M | -- |
| EVENTIDE ASSET MANAGEMENT, LLC | -- | Jun 30, 26 | -668.14K | -- |
| Aquatic Capital Management LLC | -- | Jun 30, 26 | -12.70K | -- |
| Private Advisor Group, LLC | -- | Jun 30, 26 | -6.00K | -- |
| FRANKLIN RESOURCES INC | -- | Jun 30, 26 | -684.48K | -- |
| Mirae Asset Global Investments Co., Ltd. | -- | Jun 30, 26 | -6.24K | -- |
| AMERICAN CENTURY COMPANIES INC | -- | Jun 30, 26 | -687.43K | -- |
| DEUTSCHE BANK AG\ | -- | Jun 30, 26 | -189.96K | -- |
| PFM Health Sciences, LP | -- | Jun 30, 26 | -528.22K | -- |
| Logos Global Management LP | -- | Jun 30, 26 | -2.13M | -- |
| HARVEST MANAGEMENT LLC | -- | Jun 30, 26 | -80.00K | -- |
| Burkehill Global Management, LP | -- | Jun 30, 26 | -150.00K | -- |
| LMR Partners LLP | -- | Jun 30, 26 | -125.00K | -- |
| WATER ISLAND CAPITAL LLC | -- | Jun 30, 26 | -41.00K | -- |
| BNP PARIBAS ARBITRAGE, SNC | -- | Jun 30, 26 | -2.48K | -- |
| BBR PARTNERS, LLC | -- | Jun 30, 26 | -6.55K | -- |
| GENERAL ATLANTIC, L.P. | -- | Jun 30, 26 | -1.35M | -- |
| Aspect Partners, LLC | -- | Jun 30, 26 | -30 | -- |
| BlackRock, Inc. | -- | Jun 30, 26 | -625.42K | -- |
| UBS Group AG | -- | Jun 30, 26 | -359.94K | -- |
| Octagon Capital Advisors LP | -- | Jun 30, 26 | -750.00K | -- |
| Knott David M Jr | -- | Jun 30, 26 | -39.00K | -- |
| Schonfeld Strategic Advisors LLC | -- | Jun 30, 26 | -171.93K | -- |
| Point72 Asset Management, L.P. | -- | Jun 30, 26 | -307.36K | -- |
| T. Rowe Price Investment Management, Inc. | -- | Jun 30, 26 | -170.02K | -- |
| Medicxi Ventures Management (Jersey) Ltd | -- | Jun 30, 26 | -19.96M | -- |
| Spruce Street Capital LP | -- | Jun 30, 26 | -489.85K | -- |
| FOX RUN MANAGEMENT, L.L.C. | -- | Jun 30, 26 | -14.91K | -- |
| NBC SECURITIES, INC. | -- | Jun 30, 26 | -60 | -- |
| Virtus Investment Advisers, Inc. | -- | Jun 30, 26 | -10.29K | -- |
| ROYAL BANK OF CANADA | -- | Jun 30, 26 | -1.16K | -- |
| Atria Investments, Inc | -- | Jun 30, 26 | -12.33K | -- |
| BANK OF AMERICA CORP /DE/ | -- | Jun 30, 26 | -1.93M | -- |
| GEODE CAPITAL MANAGEMENT, LLC | -- | Jun 30, 26 | -107.78K | -- |
| Bellevue Group AG | -- | Jun 30, 26 | -9.03K | -- |
| DnB Asset Management AS | -- | Jun 30, 26 | -10.39K | -- |
| PLATINUM INVESTMENT MANAGEMENT LTD | -- | Jun 30, 26 | -137.74K | -- |
| Meridian Wealth Partners, LLC | -- | Jun 30, 26 | -18.10K | -- |
| HighMark Wealth Management LLC | -- | Jun 30, 26 | -236.78K | -- |
| AXQ CAPITAL, LP | -- | Jun 30, 26 | -8.30K | -- |
| HighVista Strategies LLC | -- | Jun 30, 26 | -5.96K | -- |
| Legal & General Group Plc | -- | Jun 30, 26 | -110.21K | -- |
| SG Americas Securities, LLC | -- | Jun 30, 26 | -3.08K | -- |
| Y-Intercept (Hong Kong) Ltd | -- | Jun 30, 26 | -96.37K | -- |
| Caitong International Asset Management Co., Ltd | -- | Jun 30, 26 | -93.69K | -- |
| Greenland Capital Management LP | -- | Jun 30, 26 | -15.00K | -- |
| CITADEL ADVISORS LLC | -- | Jun 30, 26 | -598.20K | -- |
| Zurcher Kantonalbank (Zurich Cantonalbank) | -- | Jun 30, 26 | -1 | -- |
| RENAISSANCE TECHNOLOGIES LLC | -- | Jun 30, 26 | -185.00K | -- |
| Invesco Ltd. | -- | Jun 30, 26 | -7.03K | -- |
| Jain Global LLC | -- | Jun 30, 26 | -71.51K | -- |
| Paradigm Biocapital Advisors LP | -- | Jun 30, 26 | -3.57M | -- |
| Cinctive Capital Management LP | -- | Jun 30, 26 | -25.35K | -- |
| Atom Investors LP | -- | Jun 30, 26 | -158.51K | -- |
| Parallel Advisors, LLC | -- | Jun 30, 26 | -15 | -- |
| Allianz Asset Management GmbH | -- | Jun 30, 26 | -6.90K | -- |
| China Universal Asset Management Co., Ltd. | -- | Jun 30, 26 | -21.23K | -- |
| Siren, L.L.C. | -- | Jun 30, 26 | -1.05M | -- |
| Steward Partners Investment Advisory, LLC | -- | Jun 30, 26 | -81 | -- |
| MAVERICK CAPITAL LTD | -- | Jun 30, 26 | -1.85M | -- |
| Candriam S.C.A. | -- | Jun 30, 26 | -36.25K | -- |
| Virtu Financial LLC | -- | Jun 30, 26 | -67.78K | -- |
| Pictet Asset Management Holding SA | -- | Jun 30, 26 | -96.91K | -- |
| TIG Advisors, LLC | -- | Jun 30, 26 | -648.33K | -- |
| BARCLAYS PLC | -- | Jun 30, 26 | -6.92K | -- |
| GAMMA Investing LLC | -- | Jun 30, 26 | -3.98K | -- |
| Qube Research & Technologies Ltd | -- | Jun 30, 26 | -628.05K | -- |
| Freestone Grove Partners LP | -- | Jun 30, 26 | -109.33K | -- |
| GF FUND MANAGEMENT CO. LTD. | -- | Jun 30, 26 | -2.17K | -- |
| AQR Arbitrage LLC | -- | Jun 30, 26 | -98.03K | -- |
| Caption Management, LLC | -- | Jun 30, 26 | -274.12K | -- |
| Farther Finance Advisors, LLC | -- | Jun 30, 26 | -20 | -- |
| Capital World Investors | -- | Jun 30, 26 | -4.83M | -- |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | -- | Jun 30, 26 | -111.96K | -- |
| MILLENNIUM MANAGEMENT LLC | -- | Jun 30, 26 | -722.12K | -- |
| Yakira Capital Management, Inc. | -- | Jun 30, 26 | -24.00K | -- |
| JANE STREET GROUP, LLC | -- | Jun 30, 26 | -40.97K | -- |
| JBF Capital, Inc. | -- | Jun 30, 26 | -20.89K | -- |
| Bain Capital Life Sciences Investors, LLC | -- | Jun 30, 26 | -635.00K | -- |
| Woodline Partners LP | -- | Jun 30, 26 | -859.11K | -- |
| EcoR1 Capital, LLC | -- | Jun 30, 26 | -6.00M | -- |
| AMERIPRISE FINANCIAL INC | -- | Jun 30, 26 | -16.89K | -- |
| ENVESTNET ASSET MANAGEMENT INC | -- | Jun 30, 26 | -6.97K | -- |
| ProShare Advisors LLC | -- | Jun 30, 26 | -5.35K | -- |
| Nantahala Capital Management, LLC | -- | Jun 30, 26 | -254.80K | -- |
| JPMORGAN CHASE & CO | -- | Jun 30, 26 | -477.60K | -- |
| Fortress Investment Group LLC | -- | Jun 30, 26 | -20.00K | -- |
| MORGAN STANLEY | -- | Jun 30, 26 | -4.27M | -- |
| Rock Springs Capital Management LP | -- | Jun 30, 26 | -351.83K | -- |
| Ikarian Capital, LLC | -- | Jun 30, 26 | -18.11K | -- |
| BAKER BROS. ADVISORS LP | -- | Jun 30, 26 | -670.75K | -- |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | -- | Jun 30, 26 | -17.74K | -- |
| EverSource Wealth Advisors, LLC | -- | Jun 30, 26 | -12 | -- |
| Trexquant Investment LP | -- | Jun 30, 26 | -390.95K | -- |
| Foresite Capital Management VI LLC | -- | Jun 30, 26 | -1.36M | -- |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | -- | Jun 30, 26 | -13.96K | -- |
| TD Waterhouse Canada Inc. | -- | Jun 30, 26 | -15.60K | -- |
| Empirical Asset Management, LLC | -- | Jun 30, 26 | -5.08K | -- |
| Voleon Capital Management LP | -- | Jun 30, 26 | -24.17K | -- |
| Index Venture Life Associates VI Ltd | 9.96M | Mar 31, 26 | -- | 6.44% |
| Janus Henderson Group Ltd. | 3.49M | Mar 31, 26 | -600.63K | 2.26% |
| Skopos Labs, Inc. | 7.44K | Mar 31, 26 | +7.44K | 0.00% |
| CWM, LLC | -- | Mar 31, 26 | -174 | -- |
| Cubist Systematic Strategies, LLC | 103.91K | Sep 30, 25 | -172.54K | 0.07% |
| Point72 Asia (Singapore) Pte. Ltd. | 6.69K | Sep 30, 25 | +6.69K | 0.00% |
| Allostery Investments LP | 52.50K | Jun 30, 25 | -330.02K | 0.03% |
| Cutter Capital Management, LP | 418.13K | Mar 31, 25 | +271.05K | 0.27% |
| BlackRock Inc. | 464.62K | Jun 30, 24 | +82.16K | 0.30% |
| OUP Management Co., LLC | 2.94M | Sep 30, 23 | -- | 1.90% |
| Marshall Wace North America L.P. | -- | Sep 30, 21 | -34.23K | -- |
