Ionis Pharmaceuticals, Inc.IONSNASDAQ
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P/E Ratio: Discounted ValuationCompressed
Percentile Rank36
Studio
Year-over-Year Change

Price-to-earnings ratio

Latest
-33.22
↓ 102% vs avg
Percentile
P36
Within normal range
Streak
1 yr
Consecutive declineCompressed
Average
1773.76
Historical baseline
PeriodValueYoY Change
2025-33.22-188.5%
2024-11.52+41.7%
2023-19.75+0.6%
2022-19.86+86.8%
2021-150.06-744.6%
2020-17.77-158.4%
201930.41+16.4%
201826.13-99.9%
201718028.92+18946.9%
2016-95.66-