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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| Cormorant Asset Management, LP | 17.88M | Jun 30, 26 | -- | 22.30% |
| DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 4.89M | Jun 30, 26 | -- | 6.09% |
| Omega Fund Management, LLC | 3.29M | Jun 30, 26 | -- | 4.10% |
| Alphabet Inc. | 2.82M | Jun 30, 26 | -- | 3.52% |
| EcoR1 Capital, LLC | 2.82M | Jun 30, 26 | -- | 3.52% |
| WELLINGTON MANAGEMENT GROUP LLP | 2.79M | Jun 30, 26 | -29.05K | 3.48% |
| Enavate Sciences GP, LLC | 2.63M | Jun 30, 26 | -- | 3.28% |
| CITADEL ADVISORS LLC | 2.62M | Jun 30, 26 | +89.06K | 3.27% |
| Novo Holdings A/S | 2.25M | Jun 30, 26 | +64.08K | 2.81% |
| BlackRock, Inc. | 2.15M | Jun 30, 26 | +65.74K | 2.69% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.01M | Jun 30, 26 | +1.47M | 2.50% |
| Laurion Capital Management LP | 2.00M | Jun 30, 26 | +80.05K | 2.50% |
| ARMISTICE CAPITAL, LLC | 1.76M | Jun 30, 26 | +436.00K | 2.20% |
| STATE STREET CORP | 1.04M | Jun 30, 26 | +810.29K | 1.29% |
| Aisling Capital Management LP | 1.02M | Jun 30, 26 | -- | 1.27% |
| Opaleye Management Inc. | 700.00K | Jun 30, 26 | +646.72K | 0.87% |
| GEODE CAPITAL MANAGEMENT, LLC | 622.35K | Jun 30, 26 | +43.12K | 0.78% |
| Granahan Investment Management, LLC | 558.53K | Jun 30, 26 | +327.49K | 0.70% |
| SPHERA FUNDS MANAGEMENT LTD. | 460.99K | Jun 30, 26 | +460.99K | 0.57% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 400.00K | Jun 30, 26 | -- | 0.50% |
| ROYCE & ASSOCIATES LP | 384.94K | Jun 30, 26 | -251.58K | 0.48% |
| Catalio Capital Management, LP | 318.41K | Jun 30, 26 | +318.41K | 0.40% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 300.00K | Jun 30, 26 | -137.89K | 0.37% |
| VANGUARD FIDUCIARY TRUST CO | 291.52K | Jun 30, 26 | +37.19K | 0.36% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 286.52K | Jun 30, 26 | -4.29K | 0.36% |
| Sixth Street Partners Management Company, L.P. | 286.52K | Jun 30, 26 | +286.52K | 0.36% |
| Casdin Capital, LLC | 282.31K | Jun 30, 26 | -- | 0.35% |
| Ensign Peak Advisors, Inc | 273.53K | Jun 30, 26 | -47.34K | 0.34% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 244.44K | Jun 30, 26 | -4.72K | 0.30% |
| FMR LLC | 240.59K | Jun 30, 26 | +287 | 0.30% |
| BNP PARIBAS ARBITRAGE, SNC | 191.15K | Jun 30, 26 | +100.33K | 0.24% |
| NORTHERN TRUST CORP | 186.48K | Jun 30, 26 | +84.22K | 0.23% |
| Sio Capital Management, LLC | 130.63K | Jun 30, 26 | -- | 0.16% |
| UBS Group AG | 114.66K | Jun 30, 26 | +64.20K | 0.14% |
| MILLENNIUM MANAGEMENT LLC | 105.48K | Jun 30, 26 | -160.47K | 0.13% |
| GOLDMAN SACHS GROUP INC | 102.08K | Jun 30, 26 | -65.49K | 0.13% |
| MOORE CAPITAL MANAGEMENT, LP | 100.00K | Jun 30, 26 | -- | 0.12% |
| Toroso Investments, LLC | 93.34K | Jun 30, 26 | +11.17K | 0.12% |
| TEMA ETFS LLC | 93.34K | Jun 30, 26 | +11.17K | 0.12% |
| Brevan Howard Capital Management LP | 88.89K | Jun 30, 26 | +74.65K | 0.11% |
| Palumbo Wealth Management LLC | 85.62K | Jun 30, 26 | +85.62K | 0.11% |
| BANK OF AMERICA CORP /DE/ | 77.14K | Jun 30, 26 | +77.14K | 0.10% |
| Jump Financial, LLC | 62.00K | Jun 30, 26 | +62.00K | 0.08% |
| RENAISSANCE TECHNOLOGIES LLC | 58.60K | Jun 30, 26 | -43.30K | 0.07% |
| Avidity Partners Management LP | 43.85K | Jun 30, 26 | -- | 0.05% |
| TD ASSET MANAGEMENT INC | 42.73K | Jun 30, 26 | -14.84K | 0.05% |
| Virtus Investment Advisers, Inc. | 42.22K | Jun 30, 26 | +42.22K | 0.05% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 27.98K | Jun 30, 26 | -7.71K | 0.03% |
| TWO SIGMA INVESTMENTS, LP | 26.48K | Jun 30, 26 | +26.48K | 0.03% |
| Rafferty Asset Management, LLC | 22.61K | Jun 30, 26 | +22.61K | 0.03% |
| CITIGROUP INC | 19.87K | Jun 30, 26 | +19.87K | 0.02% |
| Squarepoint Ops LLC | 19.66K | Jun 30, 26 | -23.53K | 0.02% |
| Vanguard Global Advisers, LLC | 18.16K | Jun 30, 26 | -- | 0.02% |
| Schonfeld Strategic Advisors LLC | 11.50K | Jun 30, 26 | +11.50K | 0.01% |
| PROFUND ADVISORS LLC | 11.00K | Jun 30, 26 | +11.00K | 0.01% |
| AXQ CAPITAL, LP | 10.73K | Jun 30, 26 | -6.62K | 0.01% |
| MORGAN STANLEY | 3.38K | Jun 30, 26 | -39.99K | 0.00% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 2.63K | Jun 30, 26 | +2.63K | 0.00% |
| BARCLAYS PLC | 2.10K | Jun 30, 26 | +1.89K | 0.00% |
| Tower Research Capital LLC (TRC) | 1.70K | Jun 30, 26 | +1.70K | 0.00% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1.35K | Jun 30, 26 | +1.35K | 0.00% |
| Rockefeller Capital Management L.P. | 1.00K | Jun 30, 26 | +300 | 0.00% |
| Integrated Wealth Concepts LLC | 437 | Jun 30, 26 | +437 | 0.00% |
| Pacer Advisors, Inc. | 378 | Jun 30, 26 | +378 | 0.00% |
| WELLS FARGO & COMPANY/MN | 300 | Jun 30, 26 | -- | 0.00% |
| Quarry LP | 197 | Jun 30, 26 | +197 | 0.00% |
| Caitong International Asset Management Co., Ltd | 37 | Jun 30, 26 | +33 | 0.00% |
| Bellevue Group AG | -- | Jun 30, 26 | -6.98K | -- |
| ROYAL BANK OF CANADA | -- | Jun 30, 26 | -154 | -- |
| BOOTHBAY FUND MANAGEMENT, LLC | -- | Jun 30, 26 | -80.88K | -- |
| XTX Topco Ltd | -- | Jun 30, 26 | -59.74K | -- |
| Quadrature Capital Ltd | -- | Jun 30, 26 | -13.35K | -- |
| Octagon Capital Advisors LP | -- | Jun 30, 26 | -719.00K | -- |
| ExodusPoint Capital Management, LP | -- | Jun 30, 26 | -48.12K | -- |
| Aquatic Capital Management LLC | -- | Jun 30, 26 | -11.79K | -- |
| Ikarian Capital, LLC | -- | Jun 30, 26 | -270.23K | -- |
| EVENTIDE ASSET MANAGEMENT, LLC | -- | Jun 30, 26 | -541.18K | -- |
| HighVista Strategies LLC | -- | Jun 30, 26 | -78.19K | -- |
| Accent Capital Management, LLC | -- | Jun 30, 26 | -335 | -- |
| Qube Research & Technologies Ltd | -- | Jun 30, 26 | -71.92K | -- |
| Hudson Bay Capital Management LP | -- | Jun 30, 26 | -110.00K | -- |
| ACADIAN ASSET MANAGEMENT LLC | -- | Jun 30, 26 | -29.15K | -- |
| Paradigm Biocapital Advisors LP | -- | Jun 30, 26 | -868.21K | -- |
| Diametric Capital, LP | -- | Jun 30, 26 | -16.28K | -- |
| Woodline Partners LP | -- | Jun 30, 26 | -103.71K | -- |
| VANGUARD GROUP INC | 791.10K | Dec 31, 25 | +143.50K | 0.99% |
| CIBC Private Wealth Group, LLC | 5.00K | Dec 31, 25 | +5.00K | 0.01% |
Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data
