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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| Jun 2, 21 | Diker Mark N. | CTO | Sale | $80.59 | 98.03K | $7.90M | -- |
| May 26, 21 | FOTIADES GEORGE L | CEO | Sale | -- | 4.40K | -- | 134.72K |
| Jun 2, 21 | FOTIADES GEORGE L | CEO | Sale | $80.59 | 134.72K | $10.86M | -- |
| Jun 2, 21 | Forese Laura L | CTO | Sale | $80.59 | 7.57K | $610.07K | -- |
| Jun 2, 21 | EVNIN ANTHONY B | CTO | Sale | $80.59 | 12.13K | $977.72K | -- |
| Jun 2, 21 | Casner Jean | Officer | Sale | $80.59 | 10.57K | $851.51K | -- |
| Jun 2, 21 | Capone Brian | Officer | Sale | $80.59 | 12.22K | $984.49K | -- |
| Jun 2, 21 | BERMAN ANN E | CTO | Sale | $80.59 | 4.16K | $335.17K | -- |
| Jun 2, 21 | BATKIN ALAN R | CTO | Sale | $80.59 | 57.59K | $4.64M | -- |
| Apr 5, 21 | BERMAN ANN E | CTO | Sale | $82.41 | 5.50K | $453.25K | 4.16K |
| Mar 4, 21 | FOTIADES GEORGE L | CEO | Sale | $73.24 | 2.03K | $148.97K | 139.12K |
| Dec 28, 20 | Diker Mark N. | CTO | Purchase | -- | 370 | -- | 434.88K |
| Dec 28, 20 | Diker Mark N. | CTO | Sale | -- | 374 | -- | 434.50K |
| Dec 28, 20 | Diker Mark N. | CTO | Purchase | -- | 1.11K | -- | 98.03K |
| Nov 3, 20 | FOTIADES GEORGE L | CEO | Sale | -- | 31.56K | -- | 141.16K |
| Oct 23, 20 | Diker Mark N. | CTO | Purchase | -- | 9.43K | -- | 434.51K |
| Oct 23, 20 | Diker Mark N. | CTO | Purchase | -- | 47.17K | -- | 96.92K |
| Oct 10, 20 | FOTIADES GEORGE L | CEO | Sale | $47.36 | 1.05K | $49.96K | 172.72K |
| Oct 10, 20 | Casner Jean | Officer | Sale | $47.36 | 424 | $20.08K | 10.57K |
| Oct 10, 20 | Capone Brian | Officer | Sale | $47.36 | 503 | $23.82K | 12.22K |
| Oct 7, 20 | FOTIADES GEORGE L | CEO | Purchase | -- | 33.90K | -- | 173.77K |
| Oct 7, 20 | Casner Jean | Officer | Purchase | -- | 7.28K | -- | 10.99K |
| Oct 7, 20 | Capone Brian | Officer | Purchase | -- | 7.79K | -- | 12.72K |
| Apr 17, 20 | Capone Brian | Officer | Sale | $28.23 | 172 | $4.86K | 4.93K |
| Jul 31, 20 | Capone Brian | Officer | Sale | -- | -- | -- | -- |
| Jul 31, 20 | BERMAN ANN E | CTO | Purchase | -- | 1.94K | -- | 9.66K |
| Jul 31, 20 | BATKIN ALAN R | CTO | Purchase | -- | 1.94K | -- | 57.59K |
| Dec 18, 19 | Diker Mark N. | CTO | Purchase | -- | 400 | -- | 426.63K |
| Dec 20, 19 | Diker Mark N. | CTO | Sale | -- | 1.50K | -- | 425.13K |
| Jul 31, 20 | Diker Mark N. | CTO | Purchase | -- | 1.94K | -- | 425.07K |
| Feb 28, 20 | Diker Mark N. | CTO | Sale | -- | 1.99K | -- | 423.14K |
| Dec 20, 19 | Diker Mark N. | CTO | Purchase | -- | 402 | -- | 49.75K |
| Dec 18, 19 | Diker Mark N. | CTO | Purchase | -- | 800 | -- | 49.34K |
| Jul 31, 20 | EVNIN ANTHONY B | CTO | Purchase | -- | 1.94K | -- | 12.13K |
| Jul 31, 20 | Forese Laura L | CTO | Purchase | -- | 1.94K | -- | 7.57K |
| Jul 13, 20 | Capone Brian | Officer | Sale | $46.14 | 300 | $13.84K | 5.11K |
| Jul 13, 20 | Capone Brian | Officer | Sale | $44.14 | 300 | $13.24K | 5.11K |
| Mar 26, 20 | EVNIN ANTHONY B | CTO | Purchase | $37.40 | 1.30K | $48.62K | 10.20K |
| Mar 26, 20 | EVNIN ANTHONY B | CTO | Purchase | $40.37 | 1.20K | $48.44K | 8.90K |
| Mar 23, 20 | FOTIADES GEORGE L | CEO | Purchase | $21.55 | 10.00K | $215.50K | 139.88K |
| Mar 16, 20 | FOTIADES GEORGE L | CEO | Purchase | $34.22 | 8.00K | $273.76K | 129.88K |
| Mar 6, 20 | FOTIADES GEORGE L | CEO | Purchase | $52.94 | 5.00K | $264.71K | 121.88K |
| Mar 4, 20 | FOTIADES GEORGE L | CEO | Sale | $60.88 | 1.83K | $111.53K | 116.88K |
| Jan 17, 20 | Diker Mark N. | CTO | Purchase | $62.43 | 1.00K | $62.43K | 426.23K |
| Jan 17, 20 | Diker Mark N. | CTO | Purchase | $62.42 | 1.00K | $62.42K | 1.00K |
| Jan 16, 20 | FOTIADES GEORGE L | CEO | Purchase | $61.17 | 5.00K | $305.84K | 118.71K |
| Dec 12, 19 | FOTIADES GEORGE L | CEO | Sale | -- | 1.00K | -- | 118.58K |
| Jan 8, 20 | FOTIADES GEORGE L | CEO | Sale | -- | 4.88K | -- | 113.71K |
| Oct 10, 19 | Capone Brian | Officer | Purchase | -- | 2.18K | -- | 5.68K |
| Oct 10, 19 | Capone Brian | Officer | Sale | $68.89 | 276 | $19.01K | 5.41K |
| Oct 10, 19 | Conway Lawrence | President | Purchase | -- | 1.97K | -- | 5.39K |
| Oct 10, 19 | Conway Lawrence | President | Sale | $68.89 | 386 | $26.59K | 5.00K |
| Oct 10, 19 | Casner Jean | Officer | Purchase | -- | 1.89K | -- | 3.94K |
| Oct 10, 19 | Casner Jean | Officer | Sale | $68.89 | 227 | $15.64K | 3.71K |
| Oct 10, 19 | FOTIADES GEORGE L | CEO | Purchase | -- | 8.71K | -- | 119.58K |
| Jul 31, 19 | BERMAN ANN E | CTO | Purchase | -- | 713 | -- | 7.72K |
| Jul 31, 19 | NODIFF ERIC W | Officer | Sale | $91.20 | 699 | $63.75K | 34.62K |
| Jul 31, 19 | Forese Laura L | CTO | Purchase | -- | 713 | -- | 5.63K |
| Jul 31, 19 | EVNIN ANTHONY B | CTO | Purchase | -- | 713 | -- | 7.70K |
| Jul 31, 19 | BATKIN ALAN R | CTO | Purchase | -- | 713 | -- | 55.65K |
| Jul 31, 19 | Diker Mark N. | CTO | Purchase | -- | 713 | -- | 425.23K |
| Jun 5, 19 | FOTIADES GEORGE L | CEO | Sale | -- | 1.00K | -- | 110.87K |
| Apr 17, 19 | Capone Brian | Officer | Sale | $67.81 | 172 | $11.66K | 3.50K |
| Apr 9, 19 | Donnelly-Brienza Dorothy A | other: Former SVP and CHRO | Sale | $65.57 | 435 | $28.52K | 6.09K |
| Apr 5, 19 | Conway Lawrence | President | Sale | $67.00 | 800 | $53.60K | 3.42K |
| Mar 27, 19 | Capone Brian | Officer | Sale | $66.09 | 70 | $4.63K | 3.67K |
| Mar 13, 19 | Casner Jean | Officer | Sale | -- | -- | -- | 2.05K |
| Mar 4, 19 | FOTIADES GEORGE L | CEO | Purchase | -- | 17.50K | -- | 111.87K |
| Jan 3, 19 | Donnelly-Brienza Dorothy A | Officer | Sale | $73.33 | 434 | $31.83K | 6.53K |
| Dec 27, 18 | Diker Mark N. | CTO | Purchase | -- | 410 | -- | 424.52K |
| Dec 27, 18 | Diker Mark N. | CTO | Purchase | -- | 820 | -- | 48.54K |
| Nov 27, 18 | NODIFF ERIC W | Officer | Sale | -- | 130 | -- | 35.38K |
| Nov 28, 18 | NODIFF ERIC W | Officer | Sale | -- | 60 | -- | 35.32K |
| Dec 10, 18 | FOTIADES GEORGE L | CTO | Sale | -- | 1.00K | -- | 94.38K |
| Jul 31, 17 | BERMAN ANN E | CTO | Purchase | -- | 875 | -- | 6.30K |
| Oct 10, 18 | Conway Lawrence | President | Purchase | -- | 294 | -- | 4.54K |
| Oct 10, 18 | Conway Lawrence | President | Sale | $88.42 | 225 | $19.89K | 4.31K |
| Oct 10, 18 | Conway Lawrence | President | Purchase | -- | 1.53K | -- | 4.24K |
| Oct 10, 18 | Conway Lawrence | President | Sale | $84.82 | 95 | $8.06K | 4.22K |
| Oct 10, 18 | Capone Brian | Officer | Purchase | -- | 280 | -- | 3.87K |
| Oct 10, 18 | Capone Brian | Officer | Sale | $88.42 | 124 | $10.96K | 3.74K |
| Oct 10, 18 | Capone Brian | Officer | Purchase | -- | 1.45K | -- | 3.59K |
| Oct 10, 18 | NODIFF ERIC W | Officer | Purchase | -- | 952 | -- | 37.76K |
| Oct 10, 18 | NODIFF ERIC W | Officer | Purchase | -- | 2.35K | -- | 36.81K |
| Oct 10, 18 | NODIFF ERIC W | Officer | Sale | $88.42 | 1.13K | $99.91K | 36.63K |
| Oct 12, 17 | NODIFF ERIC W | Officer | Sale | $84.82 | 1.12K | $95.08K | 35.51K |
| Oct 10, 18 | Donnelly-Brienza Dorothy A | Officer | Purchase | -- | 700 | -- | 7.21K |
| Oct 10, 18 | Donnelly-Brienza Dorothy A | Officer | Sale | $88.42 | 253 | $22.37K | 6.96K |
| Oct 10, 18 | Donnelly-Brienza Dorothy A | Officer | Purchase | -- | 1.74K | -- | 6.51K |
| Sep 28, 18 | NODIFF ERIC W | Officer | Sale | $92.91 | 2.91K | $269.99K | -- |
| Jul 31, 18 | EVNIN ANTHONY B | CTO | Purchase | -- | 712 | -- | 6.98K |
| Jul 31, 18 | FOTIADES GEORGE L | CTO | Purchase | -- | 712 | -- | 95.38K |
| Jul 31, 18 | Diker Mark N. | CTO | Purchase | -- | 712 | -- | 424.11K |
| Jul 31, 18 | BERMAN ANN E | CTO | Purchase | -- | 712 | -- | 7.01K |
| Jul 31, 18 | Forese Laura L | CTO | Purchase | -- | 712 | -- | 4.92K |
| Jul 31, 18 | BATKIN ALAN R | CTO | Purchase | -- | 712 | -- | 54.94K |
| May 15, 18 | NODIFF ERIC W | Officer | Sale | $124.47 | 2.20K | $273.46K | 34.45K |
| Apr 17, 18 | Capone Brian | Officer | Sale | $113.42 | 173 | $19.62K | 2.12K |
| Dec 18, 17 | FOTIADES GEORGE L | CTO | Sale | $101.09 | 5.40K | $545.86K | 94.67K |
| Apr 10, 18 | NODIFF ERIC W | Officer | Sale | $108.31 | 1.27K | $138.09K | 36.65K |
| Jan 23, 18 | NODIFF ERIC W | Officer | Sale | $112.21 | 1.00K | $112.21K | 37.92K |
| Jan 17, 18 | Diker Mark N. | CTO | Sale | $111.56 | 3.00K | $334.67K | 425.40K |
| Jan 18, 18 | Diker Mark N. | CTO | Sale | $112.09 | 2.00K | $224.18K | 423.40K |
| Jan 3, 18 | Donnelly-Brienza Dorothy A | Officer | Sale | $101.35 | 533 | $54.02K | 4.78K |
| Dec 28, 17 | BATKIN ALAN R | CTO | Sale | -- | 10.00K | -- | 54.23K |
| Dec 26, 17 | Diker Mark N. | CTO | Purchase | -- | 260 | -- | 428.40K |
| Dec 21, 17 | Diker Mark N. | CTO | Sale | -- | 1.46K | -- | 428.14K |
| Dec 26, 17 | Diker Mark N. | CTO | Purchase | -- | 520 | -- | 47.72K |
| Dec 21, 17 | BATKIN ALAN R | CTO | Sale | -- | 7.00K | -- | 64.22K |
| Dec 18, 17 | FOTIADES GEORGE L | CTO | Sale | $101.09 | 5.70K | $576.18K | 94.37K |
| Oct 23, 17 | NODIFF ERIC W | Officer | Sale | -- | 177 | -- | 38.92K |
| Nov 1, 17 | Conway Lawrence | President | Sale | -- | -- | -- | 2.71K |
| Oct 20, 17 | NODIFF ERIC W | Officer | Sale | $97.55 | 2.87K | $279.76K | 2.91K |
| Oct 13, 17 | FOTIADES GEORGE L | CTO | Sale | $95.23 | 6.00K | $571.39K | 100.07K |
| Oct 10, 17 | NODIFF ERIC W | Officer | Sale | $96.46 | 1.78K | $172.18K | 40.10K |
| Oct 12, 17 | NODIFF ERIC W | Officer | Sale | $95.07 | 1.00K | $95.07K | 39.10K |
| Oct 10, 17 | NODIFF ERIC W | Officer | Purchase | -- | 243 | -- | 41.89K |
| Oct 10, 17 | NODIFF ERIC W | Officer | Purchase | -- | 2.04K | -- | 41.64K |
| Oct 10, 17 | NODIFF ERIC W | Officer | Sale | $96.46 | 1.94K | $186.94K | 39.95K |
| Oct 12, 17 | NODIFF ERIC W | Officer | Sale | $95.07 | 1.01K | $95.93K | 38.94K |
| Oct 10, 17 | Capone Brian | Officer | Purchase | -- | 895 | -- | 2.30K |
| Oct 10, 17 | FOTIADES GEORGE L | CTO | Purchase | -- | 520 | -- | 106.07K |
| Oct 10, 17 | Donnelly-Brienza Dorothy A | Officer | Purchase | -- | 1.50K | -- | 5.31K |
| Oct 3, 17 | Diker Mark N. | CTO | Sale | $98.90 | 7.00K | $692.33K | 429.60K |
| Oct 3, 17 | NODIFF ERIC W | Officer | Sale | $98.66 | 2.89K | $284.83K | 39.61K |
| Jul 31, 17 | FOTIADES GEORGE L | CTO | Purchase | -- | 875 | -- | 105.55K |
| Jun 13, 17 | FOTIADES GEORGE L | CTO | Sale | -- | 1.48K | -- | 104.67K |
| Jul 31, 17 | BATKIN ALAN R | CTO | Purchase | -- | 875 | -- | 71.22K |
| Jul 31, 17 | Forese Laura L | CTO | Purchase | -- | 875 | -- | 4.21K |
| Sep 30, 16 | BERMAN ANN E | CTO | Sale | $77.56 | 1.45K | $112.70K | 5.42K |
| Jul 31, 17 | EVNIN ANTHONY B | CTO | Purchase | -- | 510 | -- | 6.27K |
| Jul 31, 17 | Diker Mark N. | CTO | Purchase | -- | 875 | -- | 436.60K |
| Jun 21, 17 | Diker Mark N. | CTO | Purchase | -- | 1.28K | -- | 435.72K |
| Jun 9, 17 | Capone Brian | Officer | Sale | -- | -- | -- | 1.40K |
| May 15, 17 | NODIFF ERIC W | Officer | Sale | $71.29 | 2.40K | $171.38K | 42.50K |
| Apr 7, 17 | NODIFF ERIC W | Officer | Sale | $74.18 | 1.50K | $111.27K | 44.90K |
| Mar 15, 17 | EVNIN ANTHONY B | CTO | Purchase | $77.88 | 2.50K | $194.69K | 5.76K |
| Jan 19, 17 | NODIFF ERIC W | Officer | Sale | $76.68 | 1.12K | $85.66K | 5.77K |
| Jan 18, 17 | EVNIN ANTHONY B | CTO | Purchase | $76.26 | 2.00K | $152.53K | 3.26K |
| Jan 5, 17 | EVNIN ANTHONY B | CTO | Purchase | -- | 1.26K | -- | 1.26K |
| Jan 5, 17 | EVNIN ANTHONY B | CTO | Sale | -- | -- | -- | -- |
| Jan 3, 17 | Donnelly-Brienza Dorothy A | Officer | Purchase | -- | 3.81K | -- | 3.81K |
| Dec 29, 16 | NODIFF ERIC W | Officer | Sale | -- | 140 | -- | 46.40K |
| Jan 3, 17 | Donnelly-Brienza Dorothy A | Officer | Sale | -- | -- | -- | -- |
| Apr 4, 08 | MOORE WILLIAM M | CTO | Sale | $5.50 | 1.00K | $5.50K | -- |
| Apr 10, 08 | MOORE WILLIAM M | CTO | Sale | $3.76 | 20.00K | $75.20K | -- |
| Apr 10, 08 | MUNZENRIDER ROBERT E | CTO | Sale | $3.76 | 20.00K | $75.20K | -- |
| Nov 29, 07 | MOORE WILLIAM M | CTO | Purchase | $2.95 | 1.00K | $2.95K | 11.00K |
| Nov 29, 07 | MOORE WILLIAM M | CTO | Purchase | $2.95 | 59 | $174.05 | 10.00K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.15 | 41 | $129.15 | 9.94K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.15 | 400 | $1.26K | 9.90K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.15 | 1.00K | $3.15K | 9.50K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.15 | 800 | $2.52K | 8.50K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.05 | 200 | $610 | 7.70K |
| Nov 28, 07 | MOORE WILLIAM M | CTO | Purchase | $3.00 | 100 | $300 | 7.50K |
| Nov 26, 07 | MOORE WILLIAM M | CTO | Purchase | $3.14 | 100 | $314 | 7.40K |
| Nov 26, 07 | MOORE WILLIAM M | CTO | Purchase | $3.14 | 300 | $942 | 7.30K |
| Nov 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 100 | $341 | 7.00K |
| Nov 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 100 | $341 | 6.90K |
| Nov 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 100 | $341 | 6.80K |
| Nov 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 700 | $2.39K | 6.70K |
| Nov 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 51 | $173.91 | 6.00K |
| Nov 19, 07 | MOORE WILLIAM M | CTO | Purchase | $3.31 | 1.00K | $3.31K | 5.95K |
| Jun 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.38 | 200 | $676 | 4.95K |
| Jun 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.39 | 1.00K | $3.39K | 4.75K |
| Jun 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.40 | 1.00K | $3.40K | 3.75K |
| Jun 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.41 | 1.00K | $3.41K | 2.75K |
| Jun 20, 07 | MOORE WILLIAM M | CTO | Purchase | $3.43 | 1.75K | $6.00K | 1.75K |
| Apr 5, 07 | MUNZENRIDER ROBERT E | CTO | Purchase | $3.76 | 20.00K | $75.20K | 20.00K |
| Apr 5, 07 | MOORE WILLIAM M | CTO | Purchase | $3.76 | 20.00K | $75.20K | 20.00K |
| Apr 2, 07 | MOORE WILLIAM M | CTO | Sale | -- | -- | -- | -- |
| Apr 2, 07 | MUNZENRIDER ROBERT E | CTO | Sale | -- | -- | -- | -- |
| Nov 10, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $3.12 | 50.00K | $156.00K | 922.50K |
| Aug 23, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $3.33 | 500 | $1.67K | 872.50K |
| Aug 23, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $3.32 | 500 | $1.66K | 872.00K |
| Aug 22, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $3.00 | 500 | $1.50K | 871.50K |
| Aug 22, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $2.90 | 1.00K | $2.90K | 871.00K |
| Aug 22, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $2.80 | 1.30K | $3.64K | 870.00K |
| Aug 22, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See Remarks Section | Purchase | $2.80 | 5.00K | $14.00K | 868.70K |
| Aug 18, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See "Remarks" Page | Purchase | $2.80 | 101.00K | $282.80K | 863.70K |
| Aug 18, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See "Remarks" page | Sale | -- | -- | -- | 863.70K |
| Aug 18, 06 | BlueLine Partners, L.L.C. | 10 percent owner, other: See "Remarks" page | Sale | -- | -- | -- | 446.20K |
| Dec 12, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.54 | 16.62K | $75.45K | -- |
| Dec 7, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.75 | 801 | $3.80K | 1.40M |
| Dec 7, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.75 | 114 | $541.5 | 199.75K |
| Dec 7, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.75 | 75 | $356.25 | 131.18K |
| Dec 7, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.75 | 10 | $47.5 | 16.62K |
| Nov 29, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 9.61K | $46.14K | 1.40M |
| Nov 30, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 480 | $2.30K | 1.40M |
| Nov 29, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 1.37K | $6.57K | 199.94K |
| Nov 30, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 68 | $326.4 | 199.87K |
| Nov 29, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 900 | $4.32K | 131.30K |
| Nov 30, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 44 | $211.2 | 131.26K |
| Nov 29, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 120 | $576 | 16.64K |
| Nov 30, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $4.80 | 8 | $38.4 | 16.63K |
| Nov 14, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $5.00 | 18.90K | $94.52K | 1.41M |
| Nov 14, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $5.00 | 2.69K | $13.45K | 201.30K |
| Nov 14, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $5.00 | 1.77K | $8.85K | 132.20K |
| Nov 14, 05 | OXFORD BIOSCIENCE PARTNERS III LP | 10 percent owner | Sale | $5.00 | 237 | $1.19K | 16.76K |
