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Institutional Ownership

Top 102 Institutional Holders
HolderSharesDateChange% Held
SUVRETTA CAPITAL MANAGEMENT, LLC2.84MMar 31, 26--7.60%
JANUS HENDERSON GROUP PLC2.73MMar 31, 26+285.86K7.32%
JOHNSON & JOHNSON1.98MMar 31, 26--5.29%
FRANKLIN RESOURCES INC1.84MMar 31, 26-40.14K4.92%
BALYASNY ASSET MANAGEMENT L.P.1.69MMar 31, 26-157.16K4.51%
MILLENNIUM MANAGEMENT LLC1.54MMar 31, 26+704.76K4.11%
BAKER BROS. ADVISORS LP1.42MMar 31, 26--3.80%
RA CAPITAL MANAGEMENT, L.P.1.30MMar 31, 26-883.70K3.47%
PERCEPTIVE ADVISORS LLC1.26MMar 31, 26-209.00K3.36%
FMR LLC814.87KMar 31, 26--2.18%
Ikarian Capital, LLC807.87KMar 31, 26+525.00K2.16%
GREAT POINT PARTNERS LLC800.20KMar 31, 26+1982.14%
Longaeva Partners L.P.732.09KMar 31, 26+262.09K1.96%
SECTORAL ASSET MANAGEMENT INC727.59KMar 31, 26-73.20K1.95%
HHLR ADVISORS, LTD.669.34KMar 31, 26--1.79%
BlackRock, Inc.669.12KMar 31, 26+132.97K1.79%
Red Tree Management, LLC638.16KMar 31, 26--1.71%
Versant Venture Management, LLC542.63KMar 31, 26--1.45%
Boxer Capital Management, LLC494.00KMar 31, 26--1.32%
SUSQUEHANNA INTERNATIONAL GROUP, LLP371.64KMar 31, 26+105.88K0.99%
CITADEL ADVISORS LLC350.20KMar 31, 26+350.20K0.94%
GOLDMAN SACHS GROUP INC307.11KMar 31, 26+201.51K0.82%
SILVERARC CAPITAL MANAGEMENT, LLC301.73KMar 31, 26-5.81K0.81%
GEODE CAPITAL MANAGEMENT, LLC282.04KMar 31, 26+68.17K0.75%
ADAR1 Capital Management, LLC276.66KMar 31, 26-2.30K0.74%
Qube Research & Technologies Ltd232.53KMar 31, 26+189.46K0.62%
UBS Group AG230.41KMar 31, 26+31.02K0.62%
MARSHALL WACE, LLP226.30KMar 31, 26+45.50K0.61%
BOOTHBAY FUND MANAGEMENT, LLC222.33KMar 31, 26+149.84K0.59%
SPHERA FUNDS MANAGEMENT LTD.173.47KMar 31, 26--0.46%
VANGUARD FIDUCIARY TRUST CO153.92KMar 31, 26+153.92K0.41%
Casdin Capital, LLC148.33KMar 31, 26--0.40%
Eversept Partners, LP146.41KMar 31, 26+8.92K0.39%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC144.01KMar 31, 26+33.95K0.39%
JANE STREET GROUP, LLC107.38KMar 31, 26+79.44K0.29%
STATE STREET CORP101.28KMar 31, 26+16.85K0.27%
Verdad Advisers, LP86.03KMar 31, 26+86.03K0.23%
Point72 Asset Management, L.P.84.89KMar 31, 26-674.34K0.23%
MORGAN STANLEY70.80KMar 31, 26-53.48K0.19%
RENAISSANCE TECHNOLOGIES LLC69.40KMar 31, 26+12.30K0.19%
NORTHERN TRUST CORP65.93KMar 31, 26+12.05K0.18%
DIMENSIONAL FUND ADVISORS LP59.95KMar 31, 26+59.95K0.16%
Squarepoint Ops LLC59.84KMar 31, 26+59.84K0.16%
WELLINGTON MANAGEMENT GROUP LLP55.61KMar 31, 26+55.61K0.15%
683 Capital Management, LLC55.00KMar 31, 26-36.44K0.15%
ACADIAN ASSET MANAGEMENT LLC54.07KMar 31, 26-10.64K0.14%
Strategies Wealth Advisors, LLC50.00KMar 31, 26--0.13%
BRIDGEWAY CAPITAL MANAGEMENT, LLC49.28KMar 31, 26--0.13%
Trexquant Investment LP47.75KMar 31, 26-11.29K0.13%
BANK OF AMERICA CORP /DE/47.45KMar 31, 26+38.18K0.13%
BARCLAYS PLC43.96KMar 31, 26-15.55K0.12%
Hudson Bay Capital Management LP42.82KMar 31, 26+16.88K0.11%
Brevan Howard Capital Management LP42.18KMar 31, 26+22.75K0.11%
BNP PARIBAS ARBITRAGE, SNC39.88KMar 31, 26-24.35K0.11%
TWO SIGMA INVESTMENTS, LP37.92KMar 31, 26--0.10%
XTX Topco Ltd35.85KMar 31, 26+35.85K0.10%
AMERICAN CENTURY COMPANIES INC35.68KMar 31, 26+16.16K0.10%
INDEPENDENT FINANCIAL GROUP, LLC27.02KMar 31, 26--0.07%
Jain Global LLC22.98KMar 31, 26+22.98K0.06%
HRT FINANCIAL LP22.17KMar 31, 26+22.17K0.06%
CANADA PENSION PLAN INVESTMENT BOARD20.60KMar 31, 26+20.60K0.06%
RBF Capital, LLC20.00KMar 31, 26--0.05%
Quarry LP16.00KMar 31, 26+16.00K0.04%
Engineers Gate Manager LP14.96KMar 31, 26+14.96K0.04%
OMERS ADMINISTRATION Corp14.20KMar 31, 26-20.70K0.04%
China Universal Asset Management Co., Ltd.13.50KMar 31, 26+9.74K0.04%
Cannon Global Investment Management, LLC13.00KMar 31, 26+13.00K0.03%
Quadrature Capital Ltd12.80KMar 31, 26-10.58K0.03%
ExodusPoint Capital Management, LP12.38KMar 31, 26-38.65K0.03%
PRICE T ROWE ASSOCIATES INC /MD/11.30KMar 31, 26--0.03%
Diametric Capital, LP10.73KMar 31, 26+10.73K0.03%
Vanguard Global Advisers, LLC10.27KMar 31, 26+10.27K0.03%
CITIGROUP INC8.86KMar 31, 26-3.46K0.02%
ROYAL BANK OF CANADA5.79KMar 31, 26+2.45K0.02%
JPMORGAN CHASE & CO2.49KMar 31, 26+6960.01%
Mirae Asset Global Investments Co., Ltd.1.59KMar 31, 26+4660.00%
Federation des caisses Desjardins du Quebec1.28KMar 31, 26-1.28K0.00%
CWM, LLC1.15KMar 31, 26-350.00%
Tower Research Capital LLC (TRC)731Mar 31, 26+6070.00%
GF FUND MANAGEMENT CO. LTD.513Mar 31, 26+590.00%
Banque Transatlantique SA220Mar 31, 26--0.00%
US BANCORP \DE\123Mar 31, 26+1230.00%
ADVISOR GROUP HOLDINGS, INC.6Mar 31, 26+60.00%
Caitong International Asset Management Co., Ltd1Mar 31, 26+10.00%
COMMODORE CAPITAL LP--Mar 31, 26-816.33K--
AMERIPRISE FINANCIAL INC--Mar 31, 26-209.63K--
Schonfeld Strategic Advisors LLC--Mar 31, 26-22.67K--
OCCUDO QUANTITATIVE STRATEGIES LP--Mar 31, 26-15.04K--
GROUP ONE TRADING, L.P.--Mar 31, 26-103--
Fortitude Family Office, LLC--Mar 31, 26-445--
Graham Capital Management, L.P.--Mar 31, 26-17.07K--
Optiver Holding B.V.--Mar 31, 26-104--
Persistent Asset Partners Ltd--Mar 31, 26-13.85K--
Samsara BioCapital, LLC--Mar 31, 26-72.25K--
Monashee Investment Management LLC--Mar 31, 26-137.43K--
VANGUARD GROUP INC1.27MDec 31, 25+306.63K3.40%
Point72 Asia (Singapore) Pte. Ltd.1.83KSep 30, 25-3.01K0.00%
Point72 Europe (London) LLP179Sep 30, 25+1790.00%
Point72 (DIFC) Ltd--Sep 30, 25-65--
Cubist Systematic Strategies, LLC--Sep 30, 25-24--
Nuveen Asset Management, LLC13.31KDec 31, 24+13.31K0.04%
BlackRock Inc.396.27KJun 30, 24+396.27K1.06%

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