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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| Sep 25, 23 | Trask Anna | Officer | Sale | $3.50 | 106.86K | $374.02K | -- |
| Sep 25, 23 | Trask Anna | Officer | Sale | $3.12 | 45.00K | $140.40K | -- |
| Sep 25, 23 | Trask Anna | Officer | Sale | $3.50 | 52.50K | $183.75K | -- |
| Sep 25, 23 | Trask Anna | Officer | Sale | $4.40 | 137.30K | $604.13K | -- |
| Sep 25, 23 | Carson William H. | CTO | Sale | $2.30 | 10.00K | $23.00K | -- |
| Sep 25, 23 | Carson William H. | CTO | Sale | $3.50 | 5.00K | $17.50K | -- |
| Sep 25, 23 | Carson William H. | CTO | Sale | $4.78 | 5.00K | $23.90K | -- |
| Sep 25, 23 | Carson William H. | CTO | Sale | $8.42 | 20.00K | $168.40K | -- |
| Sep 25, 23 | Lee John Jui-Jen | Officer | Sale | $3.50 | 147.14K | $515.00K | -- |
| Sep 25, 23 | Lee John Jui-Jen | Officer | Sale | $3.12 | 45.00K | $140.40K | -- |
| Sep 25, 23 | Lee John Jui-Jen | Officer | Sale | $3.50 | 52.50K | $183.75K | -- |
| Sep 25, 23 | Lee John Jui-Jen | Officer | Sale | $4.40 | 232.00K | $1.02M | -- |
| Sep 25, 23 | FINGER ALISON CECILY | CTO | Sale | $2.30 | 10.00K | $23.00K | -- |
| Sep 25, 23 | FINGER ALISON CECILY | CTO | Sale | $6.20 | 20.00K | $124.00K | -- |
| Sep 25, 23 | FINGER ALISON CECILY | CTO | Sale | $3.50 | 5.00K | $17.50K | -- |
| Sep 25, 23 | FINGER ALISON CECILY | CTO | Sale | $4.78 | 5.00K | $23.90K | -- |
| Sep 25, 23 | MCLAUGHLIN KEVIN F | CTO | Sale | $2.88 | 20.00K | $57.60K | -- |
| Sep 25, 23 | MCLAUGHLIN KEVIN F | CTO | Sale | $4.78 | 5.00K | $23.90K | -- |
| Sep 25, 23 | MCLAUGHLIN KEVIN F | CTO | Sale | $3.50 | 5.00K | $17.50K | -- |
| Sep 25, 23 | Reid Laurence | CTO | Sale | $3.73 | 72.00K | $268.56K | -- |
| Sep 25, 23 | Reid Laurence | CTO | Sale | $3.50 | 187.50K | $656.25K | -- |
| Sep 25, 23 | Reid Laurence | CTO | Sale | $3.50 | 220.85K | $772.97K | -- |
| Sep 25, 23 | Reid Laurence | CTO | Sale | $4.40 | 1.07M | $4.72M | -- |
| Sep 25, 23 | Kapusta Matthew C | CTO | Sale | $3.34 | 10.00K | $33.40K | -- |
| Sep 25, 23 | Kapusta Matthew C | CTO | Sale | $3.50 | 10.00K | $35.00K | -- |
| Sep 25, 23 | Nochur Sara | CTO | Sale | $2.30 | 10.00K | $23.00K | -- |
| Sep 25, 23 | Nochur Sara | CTO | Sale | $6.20 | 20.00K | $124.00K | -- |
| Sep 25, 23 | Nochur Sara | CTO | Sale | $3.50 | 5.00K | $17.50K | -- |
| Sep 25, 23 | Nochur Sara | CTO | Sale | $4.78 | 5.00K | $23.90K | -- |
| Jun 13, 23 | Nochur Sara | CTO | Purchase | $4.78 | 5.00K | $23.90K | 5.00K |
| Jun 13, 23 | Nochur Sara | CTO | Purchase | -- | 5.00K | -- | 5.00K |
| Jun 13, 23 | Carson William H. | CTO | Purchase | $4.78 | 5.00K | $23.90K | 5.00K |
| Jun 13, 23 | Carson William H. | CTO | Purchase | -- | 5.00K | -- | 5.00K |
| Jun 13, 23 | FINGER ALISON CECILY | CTO | Purchase | -- | 5.00K | -- | 5.00K |
| Jun 13, 23 | FINGER ALISON CECILY | CTO | Purchase | $4.78 | 5.00K | $23.90K | 5.00K |
| Jun 13, 23 | MCLAUGHLIN KEVIN F | CTO | Purchase | $4.78 | 5.00K | $23.90K | 5.00K |
| Jun 13, 23 | MCLAUGHLIN KEVIN F | CTO | Purchase | -- | 5.00K | -- | 5.00K |
| Mar 19, 23 | Kapusta Matthew C | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Mar 19, 23 | Kapusta Matthew C | CTO | Purchase | $3.34 | 10.00K | $33.40K | 10.00K |
| Mar 19, 23 | Kapusta Matthew C | CTO | Sale | -- | -- | -- | -- |
| Mar 16, 23 | Reid Laurence | CTO | Purchase | -- | 195.00K | -- | 220.85K |
| Mar 16, 23 | Reid Laurence | CTO | Purchase | $3.73 | 72.00K | $268.56K | 72.00K |
| Jan 26, 23 | Trask Anna | Officer | Purchase | -- | 105.00K | -- | 106.86K |
| Jan 26, 23 | Trask Anna | Officer | Purchase | -- | 45.00K | -- | 45.00K |
| Jan 26, 23 | Lee John Jui-Jen | Officer | Purchase | -- | 120.00K | -- | 147.14K |
| Jan 26, 23 | Lee John Jui-Jen | Officer | Purchase | -- | 45.00K | -- | 45.00K |
| Oct 7, 22 | MURPHY JAMES B | Officer | Sale | -- | -- | -- | -- |
| Oct 10, 22 | MCLAUGHLIN KEVIN F | CTO | Purchase | -- | 20.00K | -- | 20.00K |
| Oct 10, 22 | MCLAUGHLIN KEVIN F | CTO | Sale | -- | -- | -- | -- |
| Jun 17, 22 | FINGER ALISON CECILY | CTO | Purchase | $2.30 | 10.00K | $23.00K | 10.00K |
| Jun 17, 22 | FINGER ALISON CECILY | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Jun 17, 22 | Carson William H. | CTO | Purchase | $2.30 | 10.00K | $23.00K | 10.00K |
| Jun 17, 22 | Carson William H. | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Jun 17, 22 | Thompson Peter A. | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Jun 17, 22 | Thompson Peter A. | CTO | Purchase | $2.30 | 10.00K | $23.00K | 10.00K |
| Jun 17, 22 | Nochur Sara | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Jun 17, 22 | Exter Neil | CTO | Purchase | $2.30 | 10.00K | $23.00K | 10.00K |
| Jun 17, 22 | Exter Neil | CTO | Purchase | -- | 10.00K | -- | 10.00K |
| Feb 25, 22 | Trask Anna | Officer | Purchase | $3.50 | 52.50K | $183.75K | 52.50K |
| Feb 25, 22 | Leiderman Elisabeth | CFO | Purchase | $3.50 | 52.50K | $183.75K | 52.50K |
| Feb 25, 22 | Lee John Jui-Jen | Officer | Purchase | $3.50 | 52.50K | $183.75K | 52.50K |
| Feb 25, 22 | Reid Laurence | CTO | Purchase | $3.50 | 187.50K | $656.25K | 187.50K |
| Jan 3, 22 | Trask Anna | Officer | Sale | $5.04 | 1 | $5.04 | 2.24K |
| Jan 3, 22 | Trask Anna | Officer | Sale | $5.03 | 377 | $1.90K | 1.86K |
| Dec 2, 21 | Trask Anna | Officer | Sale | $6.37 | 4.91K | $31.29K | 2.62K |
| Dec 2, 21 | Trask Anna | Officer | Sale | $6.34 | 378 | $2.39K | 2.24K |
| Dec 3, 21 | Nochur Sara | CTO | Purchase | $6.20 | 20.00K | $124.00K | 20.00K |
| Dec 3, 21 | FINGER ALISON CECILY | CTO | Purchase | $6.20 | 20.00K | $124.00K | 20.00K |
| Dec 3, 21 | Nochur Sara | CTO | Sale | -- | -- | -- | -- |
| Dec 3, 21 | FINGER ALISON CECILY | CTO | Sale | -- | -- | -- | -- |
| Nov 3, 21 | Trask Anna | Officer | Sale | $8.34 | 378 | $3.15K | 7.53K |
| Nov 2, 21 | Trask Anna | Officer | Sale | $8.31 | 4.91K | $40.83K | 7.91K |
| Oct 14, 21 | Trask Anna | Officer | Sale | $7.55 | 5.36K | $40.48K | 12.82K |
| Sep 15, 21 | Reid Laurence | CEO | Purchase | $7.64 | 10.00K | $76.40K | 25.85K |
| Aug 16, 21 | Hu Cynthia W. | Officer | Purchase | $7.37 | 150.00K | $1.11M | 150.00K |
| Aug 16, 21 | Hu Cynthia W. | Officer | Sale | -- | -- | -- | -- |
| Jun 2, 21 | Carson William H. | CTO | Purchase | $8.42 | 20.00K | $168.40K | 20.00K |
| Jun 2, 21 | Carson William H. | CTO | Sale | -- | -- | -- | -- |
| Feb 17, 21 | Schroder Adveq Technology IX S.C.S. | 10 percent owner | Purchase | $0.00 | 524.33K | $524.328 | 524.33K |
| Feb 17, 21 | Schroder Adveq Technology IX S.C.S. | 10 percent owner | Sale | -- | 6.63M | -- | -- |
| Feb 11, 21 | Schroder Adveq Technology IX S.C.S. | 10 percent owner | Sale | -- | 524.33K | -- | -- |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Purchase | $18.00 | 1.11M | $20.00M | 3.84M |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Purchase | -- | 2.73M | -- | 2.73M |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Purchase | $18.00 | 555.57K | $10.00M | 883.42K |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Purchase | -- | 327.85K | -- | 327.85K |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Purchase | -- | 218.57K | -- | 218.57K |
| Feb 17, 21 | ORBIMED ADVISORS LLC | CTO | Sale | -- | 1.16M | -- | -- |
| Feb 17, 21 | Foy Matthew | CTO | Purchase | $18.00 | 150.00K | $2.70M | 1.18M |
| Feb 17, 21 | Foy Matthew | CTO | Purchase | -- | 327.85K | -- | 1.03M |
| Feb 17, 21 | Foy Matthew | CTO | Purchase | -- | 247.32K | -- | 705.81K |
| Feb 17, 21 | Foy Matthew | CTO | Purchase | -- | 458.49K | -- | 458.49K |
| Feb 17, 21 | Foy Matthew | CTO | Sale | -- | 1.74M | -- | -- |
| Feb 17, 21 | Foy Matthew | CTO | Sale | -- | 3.13M | -- | -- |
| Feb 17, 21 | Foy Matthew | CTO | Sale | -- | 7.12M | -- | -- |
| Feb 17, 21 | Casdin Partners Master Fund, L.P. | 10 percent owner | Purchase | $18.00 | 575.00K | $10.35M | 1.12M |
| Feb 17, 21 | Casdin Partners Master Fund, L.P. | 10 percent owner | Purchase | -- | 546.42K | -- | 546.42K |
| Feb 17, 21 | Casdin Partners Master Fund, L.P. | 10 percent owner | Sale | -- | 2.90M | -- | -- |
| Feb 17, 21 | Thompson Peter A. | CTO | Purchase | $18.00 | 1.11M | $20.00M | 3.84M |
| Feb 17, 21 | Thompson Peter A. | CTO | Purchase | -- | 2.73M | -- | 2.73M |
| Feb 17, 21 | Thompson Peter A. | CTO | Purchase | $18.00 | 555.57K | $10.00M | 883.42K |
| Feb 17, 21 | Thompson Peter A. | CTO | Purchase | -- | 327.85K | -- | 327.85K |
| Feb 17, 21 | Thompson Peter A. | CTO | Purchase | -- | 218.57K | -- | 218.57K |
| Feb 17, 21 | Thompson Peter A. | CTO | Sale | -- | 1.16M | -- | -- |
| Feb 17, 21 | Exter Neil | CTO | Purchase | -- | 54.64K | -- | 3.14M |
| Feb 17, 21 | Exter Neil | CTO | Purchase | -- | 98.93K | -- | 3.09M |
| Feb 17, 21 | Exter Neil | CTO | Purchase | -- | 2.94M | -- | 2.99M |
| Feb 17, 21 | Exter Neil | CTO | Sale | -- | 289.60K | -- | -- |
| Feb 17, 21 | Exter Neil | CTO | Sale | -- | 45.64M | -- | -- |
| Feb 17, 21 | Exter Neil | CTO | Sale | -- | 1.25M | -- | -- |
| Feb 11, 21 | Exter Neil | CTO | Sale | -- | -- | -- | 47.17K |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Purchase | $18.00 | 150.00K | $2.70M | 1.18M |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Purchase | -- | 327.85K | -- | 1.03M |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Purchase | -- | 247.32K | -- | 705.81K |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Purchase | -- | 458.49K | -- | 458.49K |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 1.74M | -- | -- |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 3.13M | -- | -- |
| Feb 17, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 7.12M | -- | -- |
| Feb 17, 21 | Longevity Fund 2 LP | 10 percent owner | Purchase | -- | 79.14K | -- | 79.14K |
| Feb 17, 21 | Longevity Fund 2 LP | 10 percent owner | Sale | -- | 79.14K | -- | -- |
| Feb 17, 21 | REGENERON PHARMACEUTICALS, INC. | 10 percent owner | Purchase | -- | 2.10M | -- | 2.10M |
| Feb 17, 21 | REGENERON PHARMACEUTICALS, INC. | 10 percent owner | Sale | -- | 14.00M | -- | -- |
| Feb 17, 21 | REGENERON PHARMACEUTICALS, INC. | 10 percent owner | Sale | -- | 12.50M | -- | -- |
| Feb 17, 21 | GV 2019 GP, L.L.C. | 10 percent owner | Purchase | $0.00 | 819.63K | $819.631 | 819.63K |
| Feb 17, 21 | GV 2019 GP, L.L.C. | 10 percent owner | Sale | -- | 4.34M | -- | -- |
| Feb 17, 21 | GV 2017 GP, L.L.C. | 10 percent owner | Purchase | $0.00 | 494.65K | $494.649 | 494.65K |
| Feb 17, 21 | GV 2017 GP, L.L.C. | 10 percent owner | Sale | -- | 6.25M | -- | -- |
| Feb 17, 21 | GV 2016 GP, L.L.C. | 10 percent owner | Purchase | $0.00 | 321.98K | $321.978 | 321.98K |
| Feb 17, 21 | GV 2016 GP, L.L.C. | 10 percent owner | Sale | -- | 5.00M | -- | -- |
| Feb 11, 21 | Foy Matthew | CTO | Purchase | $18.00 | 20.00K | $360.00K | 20.00K |
| Feb 11, 21 | POON CHRISTINE A | CTO | Purchase | $18.00 | 20.00K | $360.00K | 20.00K |
| Feb 11, 21 | Exter Neil | CTO | Purchase | $18.00 | 20.00K | $360.00K | 20.00K |
| Feb 11, 21 | Thompson Peter A. | CTO | Purchase | $18.00 | 20.00K | $360.00K | 20.00K |
| Feb 11, 21 | Third Rock Ventures III, L.P. | 10 percent owner | Sale | -- | -- | -- | 47.17K |
| Feb 11, 21 | Third Rock Ventures III, L.P. | 10 percent owner | Sale | -- | 2.94M | -- | -- |
| Feb 11, 21 | Third Rock Ventures III, L.P. | 10 percent owner | Sale | -- | 98.93K | -- | -- |
| Feb 11, 21 | Third Rock Ventures III, L.P. | 10 percent owner | Sale | -- | 54.64K | -- | -- |
| Feb 11, 21 | Casdin Partners Master Fund, L.P. | 10 percent owner | Sale | -- | 546.42K | -- | -- |
| Feb 11, 21 | ORBIMED ADVISORS LLC | 10 percent owner | Sale | -- | 218.57K | -- | -- |
| Feb 11, 21 | Foy Matthew | CTO | Sale | -- | 247.32K | -- | -- |
| Feb 11, 21 | Foy Matthew | CTO | Sale | -- | 327.85K | -- | -- |
| Feb 11, 21 | Foy Matthew | CTO | Sale | -- | 458.49K | -- | -- |
| Feb 11, 21 | Steven H. Holtzman Revocable Trust | 10 percent owner | Sale | -- | -- | -- | 67.79K |
| Feb 11, 21 | Lee John Jui-Jen | Officer | Sale | -- | -- | -- | 27.14K |
| Feb 11, 21 | Lee John Jui-Jen | Officer | Sale | $4.40 | 232.00K | $1.02M | -- |
| Feb 11, 21 | Exter Neil | CTO | Sale | -- | 2.94M | -- | -- |
| Feb 11, 21 | Exter Neil | CTO | Sale | -- | 98.93K | -- | -- |
| Feb 11, 21 | Exter Neil | CTO | Sale | -- | 54.64K | -- | -- |
| Feb 11, 21 | Thompson Peter A. | CTO | Sale | -- | 218.57K | -- | -- |
| Feb 11, 21 | Reid Laurence | CTO | Sale | -- | -- | -- | 15.85K |
| Feb 11, 21 | Reid Laurence | CTO | Sale | $4.40 | 1.07M | $4.72M | -- |
| Feb 11, 21 | Leiderman Elisabeth | Officer | Sale | $4.40 | 207.31K | $912.17K | -- |
| Feb 11, 21 | Trask Anna | Officer | Sale | -- | -- | -- | 18.19K |
| Feb 11, 21 | Trask Anna | Officer | Sale | $4.40 | 137.30K | $604.13K | -- |
| Feb 11, 21 | Vigliotta Ronald | Officer | Sale | -- | -- | -- | 6.59K |
| Feb 11, 21 | Vigliotta Ronald | Officer | Sale | $4.40 | 114.02K | $501.69K | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 247.32K | -- | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 458.49K | -- | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 247.32K | -- | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 327.85K | -- | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 327.85K | -- | -- |
| Feb 11, 21 | GLAXOSMITHKLINE PLC | CTO | Sale | -- | 458.49K | -- | -- |
| Feb 11, 21 | POON CHRISTINE A | CTO | Sale | $25.97 | 4.72K | $122.47K | -- |
| Feb 11, 21 | Longevity Fund 2 LP | 10 percent owner | Sale | -- | 79.14K | -- | -- |
| Feb 11, 21 | GV 2019 GP, L.L.C. | 10 percent owner | Sale | -- | 819.63K | -- | -- |
| Feb 11, 21 | GV 2017 GP, L.L.C. | 10 percent owner | Sale | -- | 494.65K | -- | -- |
| Feb 11, 21 | GV 2016 GP, L.L.C. | 10 percent owner | Sale | -- | 321.98K | -- | -- |
| Feb 11, 21 | REGENERON PHARMACEUTICALS, INC. | 10 percent owner | Sale | -- | 989.30K | -- | -- |
| Feb 11, 21 | REGENERON PHARMACEUTICALS, INC. | 10 percent owner | Sale | -- | 1.11M | -- | -- |
