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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| May 27, 26 | CLARK IAN T | CTO | Purchase | -- | 5.09K | -- | 21.73K |
| May 27, 26 | CLARK IAN T | CTO | Purchase | $8.59 | 20.58K | $176.80K | 20.58K |
| May 27, 26 | Cohen Fred E | CTO | Purchase | -- | 5.09K | -- | 21.73K |
| May 27, 26 | Cohen Fred E | CTO | Purchase | $8.59 | 20.58K | $176.80K | 20.58K |
| May 27, 26 | SEIDENBERG BETH C | CTO | Purchase | -- | 5.09K | -- | 21.73K |
| May 27, 26 | SEIDENBERG BETH C | CTO | Purchase | $8.59 | 20.58K | $176.80K | 20.58K |
| May 27, 26 | Shaw Christi | CTO | Sale | $8.59 | 4.19K | $36.03K | 66.74K |
| May 27, 26 | Aktar Mert | CTO | Purchase | -- | 5.09K | -- | 21.73K |
| May 27, 26 | Aktar Mert | CTO | Purchase | $8.59 | 20.58K | $176.80K | 20.58K |
| May 18, 26 | Martini Gregory S. | CFO | Purchase | $8.54 | 325.00K | $2.78M | 325.00K |
| May 18, 26 | Martini Gregory S. | -- | Sale | -- | -- | -- | -- |
| May 4, 26 | Dac Nadia | Officer | Purchase | $9.00 | 300.00K | $2.70M | 300.00K |
| May 4, 26 | Dac Nadia | -- | Sale | -- | -- | -- | -- |
| Mar 13, 26 | GRASSO MARC | CFO | Purchase | $8.95 | 65.00K | $581.75K | 65.00K |
| Mar 13, 26 | GRASSO MARC | CFO | Purchase | -- | 10.00K | -- | 10.00K |
| Mar 13, 26 | Biddle Warner Weston | CEO | Purchase | $8.95 | 350.00K | $3.13M | 350.00K |
| Mar 13, 26 | Biddle Warner Weston | CEO | Purchase | -- | 58.00K | -- | 58.00K |
| Mar 13, 26 | GEHCHAN NAJI | Officer | Purchase | $8.95 | 105.00K | $939.75K | 105.00K |
| Mar 13, 26 | GEHCHAN NAJI | Officer | Purchase | -- | 18.00K | -- | 18.00K |
| Feb 24, 26 | Miller Andrew Craig | -- | Sale | -- | -- | -- | -- |
| Feb 24, 26 | Miller Andrew Craig | CTO | Purchase | $7.95 | 42.95K | $341.41K | 42.95K |
| Feb 24, 26 | Miller Andrew Craig | CTO | Purchase | -- | 11.01K | -- | 11.01K |
| Feb 24, 26 | Emany Sravan Kumar | CTO | Purchase | $7.95 | 42.95K | $341.41K | 42.95K |
| Feb 24, 26 | Emany Sravan Kumar | CTO | Purchase | -- | 11.01K | -- | 11.01K |
| Feb 24, 26 | Emany Sravan Kumar | -- | Sale | -- | -- | -- | -- |
| Feb 9, 26 | Pujols Mayobanex | -- | Sale | -- | -- | -- | -- |
| Feb 9, 26 | Pujols Mayobanex | CTO | Purchase | $8.08 | 300.00K | $2.42M | 300.00K |
| Jan 12, 26 | Shaw Christi | CTO | Purchase | $8.23 | 185.00K | $1.52M | 185.00K |
| Jan 12, 26 | Shaw Christi | CTO | Purchase | -- | 24.30K | -- | 70.94K |
| Jan 12, 26 | Shaw Christi | CTO | Purchase | -- | 30.00K | -- | 46.63K |
| Dec 18, 25 | SEIDENBERG BETH C | CTO | Purchase | $7.50 | 133.33K | $1000.00K | 869.32K |
| Dec 18, 25 | Westlake BioPartners Opportunity Fund I, L.P. | 10 percent owner | Purchase | $7.50 | 133.33K | $1000.00K | 869.32K |
| Dec 15, 25 | Walker Karen Marie | CTO | Sale | $4.83 | 24.00K | $115.91K | 85.86K |
| Dec 15, 25 | Walker Karen Marie | CTO | Purchase | $4.83 | 24.00K | $115.91K | 46.63K |
| Dec 15, 25 | Walker Karen Marie | CTO | Sale | $12.20 | 24.00K | $292.78K | 22.64K |
| Jun 30, 25 | GRASSO MARC | CFO | Sale | $3.07 | 450.00K | $1.38M | 450.00K |
| Jun 30, 25 | GRASSO MARC | -- | Sale | -- | -- | -- | -- |
| May 29, 25 | Shaw Christi | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | Shaw Christi | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| May 29, 25 | SEIDENBERG BETH C | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | SEIDENBERG BETH C | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| May 29, 25 | SPIEGELMAN DANIEL K | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | SPIEGELMAN DANIEL K | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| May 29, 25 | Aktar Mert | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | Aktar Mert | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| May 29, 25 | CLARK IAN T | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | CLARK IAN T | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| May 29, 25 | Cohen Fred E | CTO | Purchase | $2.63 | 65.35K | $171.87K | 65.35K |
| May 29, 25 | Cohen Fred E | CTO | Purchase | -- | 16.63K | -- | 16.63K |
| Apr 11, 24 | Biddle Warner Weston | CEO | Purchase | $2.06 | 332.50K | $684.95K | 332.50K |
| Apr 11, 24 | Jones Ryan Alexander | CFO | Purchase | $2.06 | 74.00K | $152.44K | 74.00K |
| Apr 11, 25 | Jones Ryan Alexander | CFO | Purchase | -- | 12.00K | -- | 55.95K |
| Apr 11, 24 | Walker Karen Marie | CTO | Purchase | $2.06 | 80.00K | $164.80K | 80.00K |
| Apr 11, 25 | Walker Karen Marie | CTO | Purchase | -- | 13.00K | -- | 22.64K |
| Feb 14, 25 | Shaw Christi | CTO | Purchase | $3.03 | 38.68K | $117.20K | 38.68K |
| Jan 22, 25 | GEHCHAN NAJI | Officer | Purchase | $3.29 | 425.00K | $1.40M | 425.00K |
| Jan 22, 25 | GEHCHAN NAJI | -- | Sale | -- | -- | -- | -- |
| Oct 21, 24 | Aktar Mert | CTO | Purchase | $5.20 | 87.74K | $456.25K | 87.74K |
| Oct 21, 24 | Aktar Mert | -- | Sale | -- | -- | -- | -- |
| Sep 16, 24 | Biddle Warner Weston | CEO | Purchase | $6.89 | 2.58M | $17.77M | 2.58M |
| Sep 16, 24 | Shaw Christi | CTO | Purchase | $6.89 | 66.59K | $458.82K | 66.59K |
| Sep 16, 24 | Biddle Warner Weston | -- | Sale | -- | -- | -- | -- |
| Sep 16, 24 | Shaw Christi | -- | Sale | -- | -- | -- | -- |
| Jun 6, 24 | Walker Karen Marie | CTO | Sale | $4.42 | 9.64K | $42.59K | 82.65K |
| Jun 6, 24 | Walker Karen Marie | CTO | Purchase | $4.42 | 9.64K | $42.59K | 9.64K |
| May 28, 24 | Jones Ryan Alexander | CFO | Purchase | $0.73 | 7.15K | $5.22K | 43.95K |
| May 28, 24 | Jones Ryan Alexander | CFO | Purchase | $0.73 | 10.87K | $7.94K | 36.80K |
| May 28, 24 | Jones Ryan Alexander | CFO | Sale | $0.73 | 7.15K | $5.22K | 2.19K |
| May 28, 24 | Jones Ryan Alexander | CFO | Sale | $0.73 | 10.87K | $7.94K | -- |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Purchase | -- | 4.52M | -- | 4.52M |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Purchase | $22.00 | 252.55K | $5.56M | 252.55K |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Purchase | $22.00 | 583 | $12.83K | 583 |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 8.83M | -- | -- |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 4.40M | -- | -- |
| Feb 12, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 7.36M | -- | -- |
| Feb 12, 24 | Cohen Fred E | CTO | Purchase | -- | 4.52M | -- | 4.52M |
| Feb 12, 24 | Cohen Fred E | CTO | Sale | -- | 4.40M | -- | -- |
| Feb 12, 24 | Cohen Fred E | CTO | Sale | -- | 8.83M | -- | -- |
| Feb 12, 24 | Cohen Fred E | CTO | Sale | -- | 7.36M | -- | -- |
| Feb 12, 24 | SEIDENBERG BETH C | CTO | Purchase | -- | 3.79M | -- | 3.79M |
| Feb 12, 24 | SEIDENBERG BETH C | CTO | Purchase | -- | 735.98K | -- | 735.98K |
| Feb 12, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 8.83M | -- | -- |
| Feb 12, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 4.40M | -- | -- |
| Feb 12, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 3.35M | -- | -- |
| Feb 12, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Purchase | -- | 3.79M | -- | 3.79M |
| Feb 12, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Purchase | -- | 735.98K | -- | 735.98K |
| Feb 12, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 3.35M | -- | -- |
| Feb 12, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 8.83M | -- | -- |
| Feb 12, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 4.40M | -- | -- |
| Feb 12, 24 | Bain Capital Life Sciences Investors, LLC | 10 percent owner | Purchase | $22.00 | 450.00K | $9.90M | 3.16M |
| Feb 12, 24 | Bain Capital Life Sciences Investors, LLC | 10 percent owner | Purchase | -- | 2.71M | -- | 2.71M |
| Feb 12, 24 | Bain Capital Life Sciences Investors, LLC | 10 percent owner | Sale | -- | 12.35M | -- | -- |
| Feb 12, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Purchase | $22.00 | 910.00K | $20.02M | 4.13M |
| Feb 12, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Purchase | -- | 3.22M | -- | 3.22M |
| Feb 12, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Sale | -- | 7.75M | -- | -- |
| Feb 12, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Sale | -- | 6.89M | -- | -- |
| Feb 12, 24 | Northpond Ventures III GP, LLC | 10% Owner | Purchase | $0.00 | 2.81M | $28.054 | 2.81M |
| Feb 12, 24 | Northpond Ventures III GP, LLC | 10% Owner | Purchase | $22.00 | 450.00K | $9.90M | 450.00K |
| Feb 12, 24 | Northpond Ventures III GP, LLC | 10% Owner | Sale | -- | 12.77M | -- | -- |
| Feb 7, 24 | Liapis Stephen Constantine | -- | Sale | -- | -- | -- | -- |
| Feb 7, 24 | SPIEGELMAN DANIEL K | CTO | Sale | $3.37 | 17.58K | $59.24K | -- |
| Feb 7, 24 | SPIEGELMAN DANIEL K | CTO | Sale | $4.83 | 32.96K | $159.19K | -- |
| Feb 7, 24 | Borie Dominique Christian | Officer | Sale | -- | -- | -- | 449.21K |
| Feb 7, 24 | Borie Dominique Christian | Officer | Sale | $4.42 | 90.35K | $399.35K | -- |
| Feb 7, 24 | Borie Dominique Christian | Officer | Sale | $4.33 | 1.10K | $4.75K | -- |
| Feb 7, 24 | Borie Dominique Christian | Officer | Sale | $4.83 | 21.97K | $106.12K | -- |
| Feb 7, 24 | CLARK IAN T | CTO | Sale | $4.42 | 38.74K | $171.21K | -- |
| Feb 7, 24 | CLARK IAN T | CTO | Sale | $4.83 | 43.95K | $212.25K | -- |
| Feb 7, 24 | Cohen Fred E | CTO | Sale | $4.83 | 32.96K | $159.19K | -- |
| Feb 7, 24 | Cohen Fred E | CTO | Sale | -- | 967.19K | -- | -- |
| Feb 7, 24 | Cohen Fred E | CTO | Sale | -- | 1.94M | -- | -- |
| Feb 7, 24 | Cohen Fred E | CTO | Sale | -- | 1.62M | -- | -- |
| Feb 7, 24 | Walker Karen Marie | CTO | Sale | $4.42 | 92.28K | $407.90K | -- |
| Feb 7, 24 | Walker Karen Marie | CTO | Sale | $4.33 | 1.10K | $4.75K | -- |
| Feb 7, 24 | Walker Karen Marie | CTO | Sale | $4.83 | 109.86K | $530.64K | -- |
| Feb 7, 24 | Chung James Bum | Officer | Sale | -- | -- | -- | 65.92K |
| Feb 7, 24 | Chung James Bum | Officer | Sale | $3.37 | 32.96K | $111.07K | -- |
| Feb 7, 24 | Chung James Bum | Officer | Sale | $4.33 | 1.10K | $4.75K | -- |
| Feb 7, 24 | Chung James Bum | Officer | Sale | $4.83 | 109.86K | $530.64K | -- |
| Feb 7, 24 | Kotzin Brian L. | CTO | Sale | $4.83 | 32.96K | $159.19K | -- |
| Aug 28, 22 | Kotzin Brian L. | CTO | Sale | $0.32 | 43.31K | $13.86K | -- |
| Feb 7, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 967.19K | -- | -- |
| Feb 7, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 1.94M | -- | -- |
| Feb 7, 24 | Vida Ventures, LLC | 10 percent owner | Sale | -- | 1.62M | -- | -- |
| Feb 7, 24 | Jones Ryan Alexander | CFO | Sale | -- | -- | -- | 25.93K |
| Feb 7, 24 | Jones Ryan Alexander | CFO | Sale | $0.73 | 9.34K | $6.82K | -- |
| Feb 7, 24 | Jones Ryan Alexander | CFO | Sale | $3.15 | 21.97K | $69.21K | -- |
| Feb 7, 24 | Jones Ryan Alexander | CFO | Sale | $4.33 | 1.10K | $4.75K | -- |
| Feb 7, 24 | Jones Ryan Alexander | CFO | Sale | $4.83 | 109.86K | $530.64K | -- |
| Feb 7, 24 | SEIDENBERG BETH C | CTO | Sale | $4.83 | 32.96K | $159.19K | -- |
| Feb 7, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 967.19K | -- | -- |
| Feb 7, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 1.94M | -- | -- |
| Feb 7, 24 | SEIDENBERG BETH C | CTO | Sale | -- | 735.98K | -- | -- |
| Feb 7, 24 | Maag Peter | CEO | Sale | -- | -- | -- | 349.32K |
| Feb 7, 24 | Maag Peter | CEO | Sale | -- | -- | -- | 58.22K |
| Feb 7, 24 | Maag Peter | CEO | Sale | $4.83 | 329.59K | $1.59M | -- |
| Feb 7, 24 | Maag Peter | CEO | Sale | $4.33 | 1.10K | $4.75K | -- |
| Feb 7, 24 | Maag Peter | CEO | Sale | $3.15 | 989.74K | $3.12M | -- |
| Feb 7, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 1.94M | -- | -- |
| Feb 7, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 967.19K | -- | -- |
| Feb 7, 24 | Westlake BioPartners Fund I, L.P. | 10 percent owner | Sale | -- | 735.98K | -- | -- |
| Feb 7, 24 | Bain Capital Life Sciences Investors, LLC | 10 percent owner | Sale | -- | 2.71M | -- | -- |
| Feb 7, 24 | Northpond Ventures III GP, LLC | 10 percent owner | Sale | -- | 2.81M | -- | -- |
| Feb 7, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Sale | -- | 1.51M | -- | -- |
| Feb 7, 24 | GILEAD SCIENCES, INC. | 10 percent owner | Sale | -- | 1.70M | -- | -- |
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