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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| Dec 12, 23 | UNITED THERAPEUTICS Corp | 10 percent owner | Sale | -- | -- | -- | 27.42M |
| Dec 12, 23 | Heine Lisa Wipperman | CTO | Sale | $1.75 | 66.94K | $117.15K | 67.41K |
| Dec 13, 23 | Heine Lisa Wipperman | CTO | Sale | -- | 67.41K | -- | -- |
| Dec 12, 23 | Maag Peter | CTO | Sale | $1.75 | 62.09K | $108.66K | 58.37K |
| Dec 13, 23 | Maag Peter | CTO | Sale | -- | 58.37K | -- | -- |
| Dec 12, 23 | ERB JOHN L | CTO | Sale | $1.75 | 56.26K | $98.45K | 54.20K |
| Dec 13, 23 | ERB JOHN L | CTO | Sale | -- | 54.20K | -- | -- |
| Dec 13, 23 | ERB JOHN L | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| Dec 12, 23 | BUCKMAN PAUL | CTO | Sale | $1.75 | 52.59K | $92.04K | 54.20K |
| Dec 13, 23 | BUCKMAN PAUL | CTO | Sale | -- | 54.20K | -- | -- |
| Dec 13, 23 | BUCKMAN PAUL | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| Dec 12, 23 | Burke William P. Mr. | CTO | Sale | $1.75 | 66.94K | $117.15K | 67.41K |
| Dec 13, 23 | Burke William P. Mr. | CTO | Sale | -- | 67.41K | -- | -- |
| Dec 12, 23 | Douglas James Michael | CFO | Sale | $1.75 | 31.25K | $54.69K | 20.00K |
| Dec 13, 23 | Douglas James Michael | CFO | Sale | -- | 20.00K | -- | -- |
| Dec 13, 23 | Douglas James Michael | CFO | Sale | $3.73 | 180.00K | $671.40K | -- |
| Dec 13, 23 | Douglas James Michael | CFO | Sale | $3.26 | 40.00K | $130.40K | -- |
| Dec 12, 23 | Ross Jeffrey James | CEO | Sale | $1.75 | 308.77K | $540.36K | 87.50K |
| Dec 13, 23 | Ross Jeffrey James | CEO | Sale | $3.26 | 100.00K | $326.00K | -- |
| Dec 13, 23 | Ross Jeffrey James | CEO | Sale | $3.75 | 68.71K | $257.68K | -- |
| Dec 13, 23 | Ross Jeffrey James | CEO | Sale | $4.73 | 1.50K | $7.10K | -- |
| Dec 13, 23 | Ross Jeffrey James | CEO | Sale | $4.20 | 100.00K | $420.00K | -- |
| Dec 13, 23 | Ross Jeffrey James | CEO | Sale | -- | 87.50K | -- | -- |
| Jun 1, 23 | Heine Lisa Wipperman | CTO | Purchase | -- | 54.20K | -- | 134.36K |
| Jun 1, 23 | Burke William P. Mr. | CTO | Purchase | -- | 54.20K | -- | 134.36K |
| Jun 1, 23 | BUCKMAN PAUL | CTO | Purchase | -- | 54.20K | -- | 106.79K |
| Jun 1, 23 | Maag Peter | CTO | Purchase | -- | 54.20K | -- | 120.46K |
| Jun 1, 23 | ERB JOHN L | CTO | Purchase | -- | 54.20K | -- | 110.46K |
| Mar 10, 23 | Douglas James Michael | CFO | Purchase | $1.60 | 31.25K | $50.00K | 51.25K |
| Mar 10, 23 | Ross Jeffrey James | CEO | Purchase | $1.60 | 31.25K | $50.00K | 396.28K |
| Mar 10, 23 | Barry John Joseph | President | Purchase | $1.60 | 6.25K | $10.00K | 35.48K |
| Mar 10, 23 | BUCKMAN PAUL | CTO | Purchase | $1.60 | 31.25K | $50.00K | 52.59K |
| Mar 10, 23 | Maag Peter | CTO | Purchase | $1.60 | 31.25K | $50.00K | 66.26K |
| Mar 10, 23 | ERB JOHN L | CTO | Purchase | $1.60 | 31.25K | $50.00K | 56.26K |
| Mar 10, 23 | Burke William P. Mr. | CTO | Purchase | $1.60 | 31.25K | $50.00K | 80.16K |
| Mar 10, 23 | Heine Lisa Wipperman | CTO | Purchase | $1.60 | 31.25K | $50.00K | 80.16K |
| Jan 13, 23 | Ross Jeffrey James | CEO | Purchase | -- | 50.00K | -- | 369.51K |
| Jan 13, 23 | Ross Jeffrey James | CEO | Sale | $3.26 | 4.49K | $14.63K | 365.03K |
| Jan 13, 23 | Ross Jeffrey James | CEO | Purchase | -- | 100.00K | -- | 100.00K |
| Jan 13, 23 | Barry John Joseph | CTO | Purchase | -- | 10.00K | -- | 29.23K |
| Jan 13, 23 | Barry John Joseph | CTO | Purchase | -- | 20.00K | -- | 20.00K |
| Jan 13, 23 | Douglas James Michael | CFO | Purchase | -- | 40.00K | -- | 40.00K |
| Jan 13, 23 | Douglas James Michael | CFO | Purchase | -- | 20.00K | -- | 20.00K |
| Dec 6, 22 | Ross Jeffrey James | CEO | Purchase | $1.25 | 37.50K | $46.88K | 331.09K |
| Dec 6, 22 | Ross Jeffrey James | CEO | Sale | $4.05 | 11.57K | $46.88K | 319.51K |
| Dec 6, 22 | Ross Jeffrey James | CEO | Sale | -- | 37.50K | -- | -- |
| Oct 1, 22 | Barry John Joseph | CTO | Sale | $4.38 | 765 | $3.35K | 19.23K |
| Aug 10, 22 | BUCKMAN PAUL | CTO | Purchase | -- | 12.79K | -- | 21.34K |
| Aug 10, 22 | Maag Peter | CTO | Purchase | -- | 12.79K | -- | 35.01K |
| Aug 10, 22 | Heine Lisa Wipperman | CTO | Purchase | -- | 12.79K | -- | 48.91K |
| Aug 10, 22 | Burke William P. Mr. | CTO | Purchase | -- | 12.79K | -- | 48.91K |
| Aug 10, 22 | ERB JOHN L | CTO | Purchase | -- | 12.79K | -- | 25.01K |
| Mar 15, 22 | Ross Jeffrey James | CEO | Purchase | $1.25 | 35.44K | $44.30K | 293.59K |
| Mar 1, 22 | Douglas James Michael | CFO | Purchase | -- | 180.00K | -- | 180.00K |
| Mar 1, 22 | Douglas James Michael | Officer | Sale | -- | -- | -- | -- |
| Jan 13, 22 | NIEBUR BRIAN | CFO | Purchase | -- | 10.00K | -- | 24.67K |
| Jan 13, 22 | NIEBUR BRIAN | CFO | Purchase | $4.20 | 20.00K | $84.00K | 20.00K |
| Jan 13, 22 | Barry John Joseph | President | Purchase | $4.20 | 20.00K | $84.00K | 20.00K |
| Jan 13, 22 | Barry John Joseph | President | Purchase | -- | 10.00K | -- | 20.00K |
| Jan 13, 22 | Kattungal Laji | President | Purchase | $4.20 | 20.00K | $84.00K | 20.00K |
| Jan 13, 22 | Kattungal Laji | President | Purchase | -- | 10.00K | -- | 10.00K |
| Jan 13, 22 | Ross Jeffrey James | CEO | Purchase | -- | 50.00K | -- | 258.15K |
| Jan 13, 22 | Ross Jeffrey James | CEO | Purchase | $4.20 | 100.00K | $420.00K | 100.00K |
| Jun 28, 21 | Ross Jeffrey James | CEO | Purchase | -- | 4.40K | -- | 208.15K |
| Jun 28, 21 | Ross Jeffrey James | CEO | Sale | -- | 4.40K | -- | -- |
| Jan 3, 22 | Ross Jeffrey James | CEO | Purchase | $4.73 | 1.50K | $7.10K | 1.50K |
| Jan 3, 22 | Kattungal Laji | President | Purchase | $4.73 | 1.50K | $7.10K | 1.50K |
| Jan 3, 22 | NIEBUR BRIAN | CFO | Purchase | $4.73 | 1.50K | $7.10K | 1.50K |
| Jan 3, 22 | Barry John Joseph | President | Purchase | $4.73 | 1.50K | $7.10K | 1.50K |
| Jan 3, 22 | Heine Lisa Wipperman | CTO | Purchase | -- | 31.71K | -- | 36.12K |
| Jan 3, 22 | Heine Lisa Wipperman | CTO | Purchase | -- | 31.71K | -- | 36.12K |
| Jan 3, 22 | Heine Lisa Wipperman | CTO | Purchase | -- | 4.41K | -- | 4.41K |
| Jan 3, 22 | Heine Lisa Wipperman | CTO | Purchase | -- | 4.41K | -- | 4.41K |
| Jan 3, 22 | Burke William P. Mr. | CTO | Purchase | -- | 31.71K | -- | 36.12K |
| Jan 3, 22 | Burke William P. Mr. | CTO | Purchase | -- | 4.41K | -- | 4.41K |
| Jan 3, 22 | Heine Lisa Wipperman | CTO | Sale | -- | -- | -- | -- |
| Jan 3, 22 | Burke William P. Mr. | CTO | Sale | -- | -- | -- | -- |
| Oct 1, 21 | NIEBUR BRIAN | CFO | Purchase | $6.97 | 50.00K | $348.50K | 50.00K |
| Oct 1, 21 | NIEBUR BRIAN | CFO | Purchase | -- | 8.00K | -- | 14.67K |
| Oct 1, 21 | Barry John Joseph | President | Purchase | $6.97 | 70.00K | $487.90K | 70.00K |
| Oct 1, 21 | Barry John Joseph | President | Purchase | -- | 10.00K | -- | 10.00K |
| Sep 9, 21 | Barry John Joseph | Officer | Sale | -- | -- | -- | -- |
| Jun 28, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Purchase | $7.50 | 1.05M | $7.85M | 1.98M |
| Jun 28, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Purchase | -- | 933.33K | -- | 933.33K |
| Jun 28, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 933.33K | -- | -- |
| Jun 28, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 1.00M | -- | -- |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Purchase | -- | 120.00K | -- | 179.77K |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Purchase | -- | 59.77K | -- | 59.77K |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Purchase | -- | 20.00K | -- | 20.00K |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Sale | -- | 59.77K | -- | -- |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Sale | -- | 20.00K | -- | -- |
| Jun 28, 21 | EIBENSTEINER RONALD E | CTO | Sale | -- | 120.00K | -- | -- |
| Jun 28, 21 | WAGNER MARK T | CTO | Purchase | -- | 3.33K | -- | 3.33K |
| Jun 28, 21 | WAGNER MARK T | CTO | Sale | -- | 3.33K | -- | -- |
| Jun 28, 21 | BUCKMAN PAUL | CTO | Purchase | -- | 3.00K | -- | 8.55K |
| Jun 28, 21 | BUCKMAN PAUL | CTO | Sale | -- | 3.00K | -- | -- |
| Jun 28, 21 | ERB JOHN L | CTO | Purchase | -- | 6.67K | -- | 12.22K |
| Jun 28, 21 | ERB JOHN L | CTO | Sale | -- | 6.67K | -- | -- |
| Jun 28, 21 | NIEBUR BRIAN | CFO | Purchase | -- | 3.33K | -- | 6.67K |
| Jun 28, 21 | NIEBUR BRIAN | CFO | Purchase | -- | 3.33K | -- | 3.33K |
| Jun 28, 21 | NIEBUR BRIAN | CFO | Sale | -- | 3.33K | -- | -- |
| Jun 28, 21 | NIEBUR BRIAN | CFO | Sale | -- | 3.33K | -- | -- |
| Jun 28, 21 | Ross Jeffrey James | CEO | Purchase | -- | 4.40K | -- | 4.40K |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Purchase | -- | 956.89K | -- | 1.00M |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Purchase | -- | 240.00K | -- | 240.00K |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 192.00K | -- | 48.00K |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | $7.50 | -- | -- | -- |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | $7.50 | 240.00K | $1.80M | -- |
| Jun 24, 21 | BAXTER INTERNATIONAL INC | 10 percent owner | Purchase | $0.00 | 2.08M | $20.833 | 2.08M |
| Jun 24, 21 | BAXTER INTERNATIONAL INC | 10 percent owner | Sale | -- | 2.08M | -- | -- |
| Jun 23, 21 | Maag Peter | CTO | Purchase | -- | 16.67K | -- | 22.22K |
| Jun 23, 21 | Maag Peter | CTO | Purchase | -- | 5.55K | -- | 5.55K |
| Jun 23, 21 | BUCKMAN PAUL | CTO | Purchase | -- | 5.55K | -- | 5.55K |
| Jun 23, 21 | ERB JOHN L | CTO | Purchase | -- | 5.55K | -- | 5.55K |
| Jun 23, 21 | BAXTER INTERNATIONAL INC | 10 percent owner | Sale | -- | 2.34M | -- | -- |
| Jun 23, 21 | BAXTER INTERNATIONAL INC | 10 percent owner | Sale | -- | 2.34M | -- | -- |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 933.33K | -- | -- |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 240.00K | -- | -- |
| Jun 23, 21 | Cheshire MD Holdings, LLC | 10 percent owner | Sale | -- | 956.89K | -- | -- |
| Jun 23, 21 | Ross Jeffrey James | CEO | Sale | -- | -- | -- | 203.75K |
| May 21, 21 | Ross Jeffrey James | CEO | Sale | $7.50 | 4.40K | $33.00K | -- |
| Jun 23, 21 | Ross Jeffrey James | CEO | Sale | $1.25 | 35.44K | $44.30K | -- |
| Jun 23, 21 | Ross Jeffrey James | CEO | Sale | $1.25 | 37.50K | $46.88K | -- |
| Jun 23, 21 | Ross Jeffrey James | CEO | Sale | $3.75 | 68.71K | $257.68K | -- |
| May 21, 21 | NIEBUR BRIAN | CFO | Sale | $7.50 | 3.33K | $25.00K | -- |
| Jun 23, 21 | NIEBUR BRIAN | CFO | Sale | $3.75 | 63.75K | $239.05K | -- |
| May 21, 21 | NIEBUR BRIAN | CFO | Sale | $7.50 | 3.33K | $25.00K | -- |
| Jun 23, 21 | ERB JOHN L | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| May 21, 21 | ERB JOHN L | CTO | Sale | $7.50 | 6.67K | $50.00K | -- |
| Jun 23, 21 | BUCKMAN PAUL | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| May 21, 21 | BUCKMAN PAUL | CTO | Sale | $7.50 | 3.00K | $22.50K | -- |
| Jul 16, 24 | Kattungal Laji | President | Sale | $3.75 | 80.00K | $300.00K | -- |
| Jun 23, 21 | WAGNER MARK T | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| May 21, 21 | WAGNER MARK T | CTO | Sale | $7.50 | 3.33K | $25.00K | -- |
| Jun 23, 21 | Maag Peter | CTO | Sale | -- | -- | -- | -- |
| Jun 23, 21 | EIBENSTEINER RONALD E | CTO | Sale | $3.75 | 25.00K | $93.75K | -- |
| May 21, 21 | EIBENSTEINER RONALD E | CTO | Sale | $2.50 | 59.77K | $149.42K | -- |
| May 21, 21 | EIBENSTEINER RONALD E | CTO | Sale | $7.50 | 120.00K | $900.00K | -- |
| May 21, 21 | EIBENSTEINER RONALD E | CTO | Sale | $7.50 | 20.00K | $150.00K | -- |
| Oct 26, 11 | EIBENSTEINER RONALD E | CTO | Sale | $1.25 | 50.00K | $62.50K | -- |
| Jun 23, 21 | EIBENSTEINER RONALD E | CTO | Sale | $1.25 | 12.50K | $15.63K | -- |
