Spero Therapeutics, Inc.SPRONASDAQ
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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| PFIZER INC | 2.36M | Sep 30, 25 | -- | -- |
| Anson Funds Management LP | 1.60M | Sep 30, 25 | -11.90K | -- |
| RENAISSANCE TECHNOLOGIES LLC | 1.45M | Sep 30, 25 | +620.60K | -- |
| Alphabet Inc. | 889.98K | Sep 30, 25 | -- | -- |
| GEODE CAPITAL MANAGEMENT, LLC | 527.48K | Sep 30, 25 | +16.78K | -- |
| BlackRock, Inc. | 434.77K | Sep 30, 25 | -- | -- |
| EAM Investors, LLC | 282.44K | Sep 30, 25 | +43.30K | -- |
| Ionic Capital Management LLC | 208.72K | Sep 30, 25 | +58.73K | -- |
| STATE STREET CORP | 190.95K | Sep 30, 25 | +37.50K | -- |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 150.52K | Sep 30, 25 | +150.52K | -- |
| NORTHERN TRUST CORP | 129.64K | Sep 30, 25 | +28.81K | -- |
| ADAR1 Capital Management, LLC | 115.54K | Sep 30, 25 | -28.38K | -- |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114.80K | Sep 30, 25 | -- | -- |
| INTREPID FAMILY OFFICE LLC | 110.00K | Sep 30, 25 | +110.00K | -- |
| GSA CAPITAL PARTNERS LLP | 106.89K | Sep 30, 25 | +106.89K | -- |
| Shay Capital LLC | 63.67K | Sep 30, 25 | +63.67K | -- |
| TWO SIGMA INVESTMENTS, LP | 49.40K | Sep 30, 25 | +49.40K | -- |
| MORGAN STANLEY | 43.38K | Sep 30, 25 | +34.16K | -- |
| JANE STREET GROUP, LLC | 42.99K | Sep 30, 25 | +42.99K | -- |
| Cubist Systematic Strategies, LLC | 40.84K | Sep 30, 25 | +13.71K | -- |
| AMERICAN CENTURY COMPANIES INC | 40.22K | Sep 30, 25 | +40.22K | -- |
| XTX Topco Ltd | 33.80K | Sep 30, 25 | -750 | -- |
| AXXCESS WEALTH MANAGEMENT, LLC | 32.55K | Sep 30, 25 | -- | -- |
| Rangeley Capital, LLC | 30.00K | Sep 30, 25 | +30.00K | -- |
| DIMENSIONAL FUND ADVISORS LP | 28.99K | Sep 30, 25 | +28.99K | -- |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 28.57K | Sep 30, 25 | -- | -- |
| Invesco Ltd. | 22.10K | Sep 30, 25 | +7.13K | -- |
| GROUP ONE TRADING, L.P. | 16.88K | Sep 30, 25 | +8.64K | -- |
| Texas Yale Capital Corp. | 10.00K | Sep 30, 25 | -- | -- |
| SIMPLEX TRADING, LLC | 7.62K | Sep 30, 25 | -22.70K | -- |
| BANK OF AMERICA CORP /DE/ | 733 | Sep 30, 25 | -4.90K | -- |
| FMR LLC | 550 | Sep 30, 25 | +550 | -- |
| ADVISOR GROUP HOLDINGS, INC. | 290 | Sep 30, 25 | -- | -- |
| JPMORGAN CHASE & CO | 236 | Sep 30, 25 | -- | -- |
| Rockefeller Capital Management L.P. | 200 | Sep 30, 25 | +200 | -- |
| WELLS FARGO & COMPANY/MN | 200 | Sep 30, 25 | -- | -- |
| NewEdge Advisors, LLC | 100 | Sep 30, 25 | -- | -- |
| BNP PARIBAS ARBITRAGE, SNC | 40 | Sep 30, 25 | -- | -- |
| SBI Securities Co., Ltd. | 10 | Sep 30, 25 | -52 | -- |
| ACADIAN ASSET MANAGEMENT LLC | -- | Sep 30, 25 | -112.89K | -- |
| ROYAL BANK OF CANADA | -- | Sep 30, 25 | -5.74K | -- |
| MONIMUS CAPITAL MANAGEMENT, LP | -- | Sep 30, 25 | -310.91K | -- |
| Stonepine Capital Management, LLC | -- | Sep 30, 25 | -156.89K | -- |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | -- | Sep 30, 25 | -69.81K | -- |
| Tower Research Capital LLC (TRC) | -- | Sep 30, 25 | -603 | -- |
| Quadrature Capital Ltd | -- | Sep 30, 25 | -31.20K | -- |
| CULLEN/FROST BANKERS, INC. | -- | Sep 30, 25 | -2.00K | -- |
| RAYMOND JAMES FINANCIAL INC | -- | Sep 30, 25 | -3.08K | -- |
| Schonfeld Strategic Advisors LLC | -- | Sep 30, 25 | -510.83K | -- |
| EP Wealth Advisors, LLC | -- | Jun 30, 25 | -16.50K | -- |
| WR Wealth Planners, LLC | 2.60K | Dec 31, 24 | -- | -- |
| BlackRock Inc. | 483.40K | Jun 30, 24 | +6.51K | -- |
| Atlas Venture Associates IX, LLC | 1.35M | Sep 30, 23 | -- | -- |
| OUP Management Co., LLC | 249.07K | Sep 30, 23 | -- | -- |
| GOFEN & GLOSSBERG LLC /IL/ | 17.50K | Dec 31, 22 | -- | -- |
| Kingsbury Capital Investment Advisors LLC | -- | Sep 30, 22 | -60.84K | -- |
| PARAMETRIC PORTFOLIO ASSOCIATES LLC | 44.17K | Mar 31, 22 | +44.17K | -- |
| Amalgamated Financial Corp. | 3.89K | Mar 31, 22 | +3.89K | -- |
| IndexIQ Advisors LLC | -- | Mar 31, 22 | -28.69K | -- |
| Carroll Financial Associates, Inc. | 110 | Dec 31, 21 | -- | -- |
| Atlas Venture Associates XI, LLC | 1.38M | Dec 31, 20 | +1.38M | -- |
| Winslow, Evans & Crocker, Inc. | 1.64K | Dec 31, 20 | -- | -- |
| VHCP Management II, LLC | 474.01K | Dec 31, 19 | -- | -- |