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| Date | Insider | Title | Type | Price | Shares | Value | Owned After |
|---|---|---|---|---|---|---|---|
| Jan 2, 24 | Pelletier Nadege | Officer | Purchase | $3.70 | 105.00K | $388.50K | 105.00K |
| Jan 2, 24 | Griffiths Graham | Officer | Purchase | $3.70 | 96.50K | $357.05K | 96.50K |
| Jan 2, 24 | Enright William | CEO | Purchase | $3.70 | 443.98K | $1.64M | 443.98K |
| Jan 2, 24 | Brown Gemma | CFO | Purchase | $3.70 | 193.00K | $714.10K | 193.00K |
| Jun 26, 23 | Scheeren Joseph | CTO | Purchase | $2.44 | 10.00K | $24.40K | 23.00K |
| May 25, 23 | Wright Robin | CTO | Purchase | $2.66 | 13.75K | $36.61K | 48.26K |
| May 11, 23 | Wright Robin | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| May 11, 23 | Scheeren Joseph | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| May 11, 23 | Phillips Anne M. | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| May 11, 23 | Morgon Pierre A. | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| May 11, 23 | Hammacher Alex | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| May 11, 23 | DAWES KAREN A | CTO | Purchase | $2.27 | 19.20K | $43.58K | 19.20K |
| Jan 3, 23 | Marshall Margaret | Officer | Purchase | $2.40 | 60.00K | $144.00K | 60.00K |
| Jan 3, 23 | Evans Thomas George | Officer | Purchase | $2.40 | 125.00K | $300.00K | 125.00K |
| Mar 27, 23 | Enright William | CEO | Sale | $2.42 | 15.00K | $36.30K | 728.45K |
| Feb 1, 23 | Pelletier Nadege | Officer | Purchase | $2.90 | 485.00K | $1.41M | 485.00K |
| Jan 30, 23 | Pelletier Nadege | Officer | Sale | -- | -- | -- | -- |
| Jan 3, 23 | Griffiths Graham | Officer | Purchase | $2.40 | 105.00K | $252.00K | 105.00K |
| Jan 3, 23 | Enright William | CEO | Purchase | $2.40 | 440.00K | $1.06M | 440.00K |
| Jan 3, 23 | Ellis Christopher | COO | Purchase | $2.40 | 105.00K | $252.00K | 105.00K |
| Jan 3, 23 | Brown Gemma | CFO | Purchase | $2.40 | 33.10K | $79.44K | 33.10K |
| Jun 15, 22 | Wright Robin | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Jun 15, 22 | Scheeren Joseph | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Jun 15, 22 | Phillips Anne M. | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Jun 15, 22 | Morgon Pierre A. | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Jun 15, 22 | Hammacher Alex | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Jun 15, 22 | DAWES KAREN A | CTO | Purchase | $4.27 | 18.60K | $79.44K | 18.60K |
| Sep 30, 22 | M&G Alternatives Investment Management Ltd | CTO | Sale | -- | 4.11M | -- | -- |
| Sep 30, 22 | M&G INVESTMENT MANAGEMENT LTD | CTO | Purchase | -- | 4.11M | -- | 5.20M |
| Sep 26, 22 | Brown Gemma | CFO | Purchase | $3.07 | 334.00K | $1.03M | 334.00K |
| Aug 25, 22 | Griffiths Graham | Officer | Sale | $7.39 | 10.00K | $73.87K | 104.21K |
| Aug 24, 22 | Ellis Christopher | COO | Sale | -- | 450 | -- | 40.16K |
| Aug 24, 22 | Ellis Christopher | COO | Sale | $7.07 | 25.00K | $176.71K | 75 |
| Aug 17, 22 | Ellis Christopher | COO | Sale | -- | 2.17K | -- | 40.61K |
| Aug 17, 22 | Ellis Christopher | COO | Sale | $4.84 | 2.17K | $10.53K | 75 |
| Aug 17, 22 | Griffiths Graham | Officer | Sale | $4.76 | 500 | $2.38K | 114.21K |
| Aug 15, 22 | Ellis Christopher | COO | Purchase | $0.00 | 5.35K | $2.14 | 5.42K |
| Aug 15, 22 | Ellis Christopher | COO | Sale | $4.78 | 2.20K | $10.51K | 75 |
| Aug 15, 22 | Griffiths Graham | Officer | Sale | $4.82 | 1.22K | $5.88K | 114.71K |
| Aug 12, 22 | Griffiths Graham | Officer | Sale | $4.50 | 5.00K | $22.50K | 118.33K |
| Jun 28, 22 | Ellis Christopher | COO | Purchase | $0.00 | 5 | $0.002 | 80 |
| Jun 28, 22 | Ellis Christopher | COO | Sale | $6.00 | 5 | $30 | 75 |
| Jun 23, 22 | Griffiths Graham | Officer | Purchase | $5.87 | 100 | $586.8 | 123.33K |
| Jun 23, 22 | Griffiths Graham | Officer | Sale | $5.28 | 8 | $42.24 | 123.23K |
| Jun 23, 22 | Griffiths Graham | Officer | Sale | -- | 1.93K | -- | -- |
| Apr 1, 22 | Scheeren Joseph | CTO | Purchase | $5.09 | 10.00K | $50.90K | 13.00K |
| Mar 31, 22 | Hammacher Alex | CTO | Purchase | $5.14 | 2.00K | $10.28K | 3.00K |
| Dec 17, 21 | Griffiths Graham | Officer | Purchase | $0.00 | 3.09K | $1.236 | 115.90K |
| Dec 17, 21 | Griffiths Graham | Officer | Purchase | $0.00 | 4.64K | $1.854 | 112.81K |
| Dec 17, 21 | Griffiths Graham | Officer | Purchase | $0.00 | 5.79K | $2.318 | 108.17K |
| Dec 17, 21 | Griffiths Graham | Officer | Purchase | $0.00 | 102.28K | $40.912 | 102.38K |
| Dec 17, 21 | Griffiths Graham | Officer | Sale | $0.00 | 3.09K | $1.236 | 9.27K |
| Dec 17, 21 | Griffiths Graham | Officer | Sale | $0.00 | 4.64K | $1.854 | 4.63K |
| Dec 17, 21 | Griffiths Graham | Officer | Sale | $0.00 | 5.79K | $2.318 | 1.93K |
| Dec 17, 21 | Griffiths Graham | Officer | Sale | $0.00 | 102.28K | $40.912 | -- |
| Jan 3, 22 | Marshall Margaret | Officer | Purchase | $11.12 | 80.00K | $889.60K | 80.00K |
| Jan 3, 22 | Griffiths Graham | Officer | Purchase | $11.12 | 80.00K | $889.60K | 80.00K |
| Jan 3, 22 | Evans Thomas George | Officer | Purchase | $11.12 | 80.00K | $889.60K | 80.00K |
| Jan 3, 22 | Ellis Christopher | COO | Purchase | $11.12 | 80.00K | $889.60K | 80.00K |
| Jan 3, 22 | Enright William | CEO | Purchase | $11.12 | 359.61K | $4.00M | 359.61K |
| Jan 3, 22 | Egorov Georgy | CFO | Purchase | $11.12 | 114.00K | $1.27M | 114.00K |
| Dec 31, 21 | Hammacher Alex | CTO | Purchase | $10.86 | 1.00K | $10.86K | 1.00K |
| Dec 22, 21 | Wright Robin | CTO | Purchase | $9.97 | 10.00K | $99.70K | 34.51K |
| Apr 29, 21 | M&G Alternatives Investment Management Ltd | 10 percent owner | Sale | -- | -- | -- | 4.11M |
| May 4, 21 | Enright William | CEO | Purchase | -- | 514.92K | -- | 1.26M |
| May 4, 21 | DAWES KAREN A | CTO | Purchase | $17.00 | 1.70K | $28.90K | 1.70K |
| May 4, 21 | Griffiths Graham | Officer | Purchase | $17.00 | 100 | $1.70K | 100 |
| May 4, 21 | Wright Robin | CTO | Purchase | $17.00 | 14.00K | $238.00K | 24.51K |
| May 4, 21 | Ellis Christopher | COO | Purchase | $17.00 | 75 | $1.27K | 75 |
| May 4, 21 | Scheeren Joseph | CTO | Purchase | $17.00 | 3.00K | $51.00K | 3.00K |
| May 4, 21 | Phillips Anne M. | CTO | Purchase | $17.00 | 3.00K | $51.00K | 3.00K |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Purchase | $17.00 | 600.00K | $10.20M | 8.80M |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Purchase | -- | 1.66M | -- | 8.20M |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Purchase | -- | 1.70M | -- | 6.54M |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Purchase | -- | 4.83M | -- | 4.83M |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 1.66M | -- | -- |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 1.70M | -- | -- |
| May 4, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 4.83M | -- | -- |
| Apr 29, 21 | Wright Robin | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | Scheeren Joseph | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | Phillips Anne M. | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | Morgon Pierre A. | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | Hammacher Alex | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | DAWES KAREN A | CTO | Purchase | $17.00 | 34.33K | $583.58K | 34.33K |
| Apr 29, 21 | Enright William | CEO | Purchase | -- | 455.77K | -- | 1.20M |
| Apr 29, 21 | Enright William | CEO | Purchase | $17.00 | 176.13K | $2.99M | 176.13K |
| Apr 29, 21 | Marshall Margaret | Officer | Purchase | $17.00 | 225.57K | $3.83M | 225.57K |
| Apr 29, 21 | Marshall Margaret | Officer | Purchase | $17.00 | 7.78K | $132.31K | 7.78K |
| Apr 29, 21 | Griffiths Graham | Officer | Purchase | $17.00 | 88.06K | $1.50M | 88.06K |
| Apr 29, 21 | Griffiths Graham | Officer | Purchase | $17.00 | 6.05K | $102.92K | 6.05K |
| Apr 29, 21 | Evans Thomas George | Officer | Purchase | $17.00 | 364.62K | $6.20M | 364.62K |
| Apr 29, 21 | Evans Thomas George | Officer | Purchase | $17.00 | 6.94K | $118.01K | 6.94K |
| Apr 29, 21 | Ellis Christopher | COO | Purchase | $17.00 | 97.33K | $1.65M | 97.33K |
| Apr 29, 21 | Ellis Christopher | COO | Purchase | $17.00 | 5.71K | $97.04K | 5.71K |
| Apr 29, 21 | Egorov Georgy | CFO | Purchase | $17.00 | 149.87K | $2.55M | 149.87K |
| Apr 29, 21 | Egorov Georgy | CFO | Purchase | $17.00 | 6.92K | $117.61K | 6.92K |
| Apr 30, 21 | M&G INVESTMENT MANAGEMENT LTD | 10 percent owner | Purchase | $14.40 | 125.00K | $1.80M | 1.09M |
| Apr 29, 21 | M&G INVESTMENT MANAGEMENT LTD | 10 percent owner | Sale | -- | -- | -- | 963.60K |
| Apr 29, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 4.83M | -- | -- |
| Apr 29, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 1.70M | -- | -- |
| Apr 29, 21 | Oxford Sciences Innovation plc | 10 percent owner | Sale | -- | 1.66M | -- | -- |
| Apr 29, 21 | Scheeren Joseph | CTO | Sale | -- | -- | -- | -- |
| Apr 29, 21 | Phillips Anne M. | CTO | Sale | -- | -- | -- | -- |
| Apr 29, 21 | Morgon Pierre A. | CTO | Sale | -- | -- | -- | 10.51K |
| Apr 29, 21 | Morgon Pierre A. | CTO | Sale | $0.00 | 20.39K | $2.039 | -- |
| Apr 29, 21 | Marshall Margaret | Officer | Sale | $0.00 | 88.06K | $35.226 | -- |
| Apr 29, 21 | Hammacher Alex | CTO | Sale | -- | -- | -- | -- |
| Apr 29, 21 | Wright Robin | CTO | Sale | -- | -- | -- | 10.51K |
| Apr 29, 21 | Wright Robin | CTO | Sale | $0.00 | 20.39K | $2.039 | -- |
| Apr 29, 21 | Evans Thomas George | Officer | Sale | -- | -- | -- | 127.93K |
| Apr 29, 21 | Evans Thomas George | Officer | Sale | $0.00 | 12.36K | $4.944 | -- |
| Apr 29, 21 | Evans Thomas George | Officer | Sale | $0.00 | 30.90K | $3.09 | -- |
| Apr 29, 21 | Enright William | CEO | Sale | -- | -- | -- | 743.45K |
| Apr 29, 21 | Ellis Christopher | COO | Sale | $0.00 | 12.36K | $4.944 | -- |
| Apr 29, 21 | Ellis Christopher | COO | Sale | $0.00 | 30.90K | $3.09 | -- |
| Apr 29, 21 | Egorov Georgy | CFO | Sale | $0.00 | 176.13K | $70.452 | -- |
| Apr 29, 21 | Griffiths Graham | Officer | Sale | $0.00 | 12.36K | $4.944 | -- |
| Apr 29, 21 | Griffiths Graham | Officer | Sale | $0.00 | 30.90K | $3.09 | -- |
| Apr 29, 21 | DAWES KAREN A | CTO | Sale | -- | -- | -- | -- |
