ACADIA Pharmaceuticals Inc. (ACAD) Q1 2026 Earnings Call Transcript
ACADIA Pharmaceuticals Inc. (ACAD) Q1 2026 Earnings Call Transcript

Net interest margin trajectory - spread between portfolio yield and repo financing costs, heavily influenced by yield curve shape and Fed policy
Book value per share changes - mark-to-market adjustments on MBS portfolio driven by interest rate movements and credit spread volatility
Prepayment speeds on underlying mortgages - accelerating refinancing activity compresses yields and forces reinvestment at lower rates
Dividend sustainability signals - current payout relative to economic earnings and book value trends determines income investor demand
moderate - Agency MBS credit performance is largely insulated from economic cycles due to government guarantees, but non-agency RMBS and whole loans face higher delinquency risk during recessions. Housing market strength affects prepayment speeds and new origination opportunities. The primary cycle sensitivity comes through Fed policy responses to economic conditions rather than direct credit losses.
Extreme sensitivity to interest rate levels and yield curve shape. Rising short-term rates increase repo financing costs immediately while asset yields adjust slowly, compressing NIM. Flattening or inverted yield curves eliminate the positive carry that makes the business model viable. Conversely, steepening curves expand spreads. The company uses interest rate swaps and swaptions to hedge duration risk, but basis risk and hedge costs reduce profitability. Mark-to-market losses on MBS holdings during rate increases create book value volatility even if held to maturity. The 0.4x price-to-book suggests investors expect continued book value erosion in current rate environment.
Secular decline in mortgage REIT profitability as Fed balance sheet normalization reduces agency MBS supply and compresses spreads - QT removes natural bid for assets
Regulatory changes to GSE reform or capital requirements for repo counterparties could reduce leverage capacity or increase funding costs
Structural shift to floating-rate mortgages or alternative housing finance reduces fixed-rate MBS investment opportunities
dividend - Mortgage REITs attract income-focused investors seeking high current yields (CIM likely yields 12-15% based on 0.4x P/B discount), though the depressed valuation suggests dividend sustainability concerns. Value investors may see opportunity in the P/B discount if they believe book value stabilizes, but this is a leveraged bet on interest rate positioning rather than traditional value investing. Not suitable for growth or momentum investors given the mature, spread-compression business model.
Trend
+2.4% vs SMA 50 · +3.3% vs SMA 200
Momentum
Volume distribution is neutral or leaning toward distribution. No compelling squeeze setup based on current money flow data.
Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.
Analyst consensus estimates · Actuals replace estimates as reported
| Year | Revenue Est. | Rev Gth | EPS Est. | EPS Gth | Range | Analysts |
|---|---|---|---|---|---|---|
FY2023 | $306.4M $228.5M–$357.2M | — | $1.79 | — | ±27% | Low1 |
FY2024 | $279.6M $208.5M–$325.9M | ▼ -8.8% | $1.49 | ▼ -16.6% | ±27% | Low2 |
FY2025 | $339.1M $252.9M–$395.3M | ▲ +21.3% | $1.77 | ▲ +18.8% | ±27% | Moderate3 |
Dividend per payment — last 8 periods
ACADIA Pharmaceuticals Inc. (ACAD) Q1 2026 Earnings Call Transcript

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| Symbol | Price | Day % | Mkt Cap↓ | P/E | Rev Grw | Margin | ELO |
|---|---|---|---|---|---|---|---|
CIM◀ | $13.63 | -0.07% | $1.1B | 4.8 | +21821.6% | 2808.3% | 1500 |
| $314.90 | +1.78% | $834.5B | 14.9 | +330.7% | 2039.3% | 1504 | |
| $318.80 | -1.00% | $617.3B | 27.4 | +1134.0% | 5014.5% | 1499 | |
| $491.89 | -1.04% | $440.0B | 28.1 | +1641.6% | 4564.7% | 1489 | |
| $53.60 | +0.90% | $377.0B | 12.3 | -45.1% | 1592.6% | 1503 | |
| $193.35 | +2.13% | $300.4B | 16.7 | +1147.7% | 1466.4% | 1517 | |
| $937.35 | +2.01% | $272.7B | 15.8 | -138.4% | 1373.0% | 1515 | |
| Sector avg | — | +0.67% | — | 17.2 | +3698.9% | 2694.1% | 1504 |