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Institutional Ownership

Top 169 Institutional Holders
HolderSharesDateChange% Held
Frazier Life Sciences Management, L.P.6.65MMar 31, 26--19.80%
ORBIMED ADVISORS LLC3.64MMar 31, 26-297.32K10.83%
NEA Management Company, LLC3.61MMar 31, 26--10.76%
WELLINGTON MANAGEMENT GROUP LLP3.19MMar 31, 26-158.14K9.50%
BlackRock, Inc.2.94MMar 31, 26+21.65K8.76%
FMR LLC2.94MMar 31, 26+2.92M8.74%
Deep Track Capital, LP2.76MMar 31, 26-492.22K8.21%
NVP Associates, LLC2.14MMar 31, 26--6.36%
Polar Capital Holdings Plc1.62MMar 31, 26+1.62M4.83%
BRAIDWELL LP1.49MMar 31, 26+473.87K4.44%
Aaron Wealth Advisors LLC1.17MMar 31, 26+1.10M3.48%
Cormorant Asset Management, LP1.12MMar 31, 26--3.33%
PRICE T ROWE ASSOCIATES INC /MD/1.03MMar 31, 26+188.50K3.06%
DRIEHAUS CAPITAL MANAGEMENT LLC1.02MMar 31, 26-389.95K3.03%
Kynam Capital Management, LP934.80KMar 31, 26--2.78%
CITADEL ADVISORS LLC932.83KMar 31, 26+122.98K2.78%
Woodline Partners LP900.06KMar 31, 26-100.00K2.68%
EVENTIDE ASSET MANAGEMENT, LLC890.00KMar 31, 26--2.65%
Caligan Partners LP848.59KMar 31, 26+848.59K2.53%
Parkman Healthcare Partners LLC800.04KMar 31, 26-85.60K2.38%
STATE STREET CORP787.21KMar 31, 26+114.47K2.34%
EcoR1 Capital, LLC777.00KMar 31, 26-1.35M2.31%
GEODE CAPITAL MANAGEMENT, LLC670.38KMar 31, 26+20.99K2.00%
TCG Crossover Management, LLC650.00KMar 31, 26--1.93%
MILLENNIUM MANAGEMENT LLC564.41KMar 31, 26+102.37K1.68%
StemPoint Capital LP499.47KMar 31, 26+420.92K1.49%
GOLDMAN SACHS GROUP INC457.94KMar 31, 26+126.01K1.36%
UBS Group AG346.91KMar 31, 26+65.70K1.03%
Candriam S.C.A.294.37KMar 31, 26+294.37K0.88%
D. E. Shaw & Co., Inc.288.89KMar 31, 26-382.95K0.86%
Rock Springs Capital Management LP287.97KMar 31, 26+5.34K0.86%
Opaleye Management Inc.260.00KMar 31, 26--0.77%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC214.91KMar 31, 26-7.27K0.64%
NORTHERN TRUST CORP210.57KMar 31, 26+19.69K0.63%
BOOTHBAY FUND MANAGEMENT, LLC208.05KMar 31, 26+208.05K0.62%
Soleus Capital Management, L.P.178.90KMar 31, 26-230.00K0.53%
DAFNA Capital Management LLC175.47KMar 31, 26+10.20K0.52%
VANGUARD FIDUCIARY TRUST CO170.15KMar 31, 26+170.15K0.51%
Goelzer Investment Management, Inc.164.17KMar 31, 26-57.50K0.49%
Affinity Asset Advisors, LLC150.00KMar 31, 26-100.00K0.45%
JPMORGAN CHASE & CO147.06KMar 31, 26+132.41K0.44%
TFG Asset Management GP Ltd145.48KMar 31, 26+2.15K0.43%
Schonfeld Strategic Advisors LLC123.81KMar 31, 26-43.31K0.37%
TD ASSET MANAGEMENT INC116.00KMar 31, 26+14.55K0.35%
TWO SIGMA INVESTMENTS, LP115.08KMar 31, 26-23.50K0.34%
Burkehill Global Management, LP100.00KMar 31, 26--0.30%
Squarepoint Ops LLC97.22KMar 31, 26+50.51K0.29%
MANUFACTURERS LIFE INSURANCE COMPANY, THE90.63KMar 31, 26+21.08K0.27%
Nuveen, LLC81.79KMar 31, 26+6.23K0.24%
Bank of New York Mellon Corp80.22KMar 31, 26+4.96K0.24%
PFM Health Sciences, LP71.89KMar 31, 26-7.42K0.21%
VICTORY CAPITAL MANAGEMENT INC71.03KMar 31, 26+71.03K0.21%
MARSHALL WACE, LLP62.70KMar 31, 26+62.70K0.19%
SCHRODER INVESTMENT MANAGEMENT GROUP57.32KMar 31, 26-16.41K0.17%
XTX Topco Ltd53.21KMar 31, 26+33.07K0.16%
DIMENSIONAL FUND ADVISORS LP46.75KMar 31, 26+46.75K0.14%
Swiss National Bank44.40KMar 31, 26+44.40K0.13%
PLATINUM INVESTMENT MANAGEMENT LTD43.60KMar 31, 26--0.13%
ALPS ADVISORS INC36.55KMar 31, 26-3220.11%
ALGERT GLOBAL LLC36.02KMar 31, 26+36.02K0.11%
Creative Planning35.97KMar 31, 26+2.32K0.11%
EXCHANGE TRADED CONCEPTS, LLC34.26KMar 31, 26+34.26K0.10%
RHUMBLINE ADVISERS33.87KMar 31, 26+4510.10%
MORGAN STANLEY31.56KMar 31, 26-27.46K0.09%
ALLIANCEBERNSTEIN L.P.30.50KMar 31, 26+2.60K0.09%
ExodusPoint Capital Management, LP28.09KMar 31, 26-28.92K0.08%
Invesco Ltd.27.52KMar 31, 26+6.32K0.08%
AQR CAPITAL MANAGEMENT LLC27.39KMar 31, 26-4.02K0.08%
DEUTSCHE BANK AG\22.95KMar 31, 26+2.92K0.07%
Cerity Partners LLC21.16KMar 31, 26-1600.06%
Legal & General Group Plc19.36KMar 31, 26+16.82K0.06%
STATE OF WISCONSIN INVESTMENT BOARD19.26KMar 31, 26+19.26K0.06%
Koa Wealth Management, LLC17.91KMar 31, 26-5000.05%
Engineers Gate Manager LP17.38KMar 31, 26+17.38K0.05%
Qube Research & Technologies Ltd17.19KMar 31, 26-6.03K0.05%
Vanguard Global Advisers, LLC16.03KMar 31, 26+16.03K0.05%
MetLife Investment Management, LLC16.02KMar 31, 26--0.05%
VANGUARD ASSET MANAGEMENT, Ltd14.75KMar 31, 26+14.75K0.04%
Optimize Financial Inc14.51KMar 31, 26+14.51K0.04%
CITIGROUP INC13.50KMar 31, 26-2.89K0.04%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.13.32KMar 31, 26+670.04%
Jump Financial, LLC12.70KMar 31, 26+12.70K0.04%
BARCLAYS PLC11.84KMar 31, 26-40.85K0.04%
HighVista Strategies LLC11.47KMar 31, 26+11.47K0.03%
CANADA PENSION PLAN INVESTMENT BOARD10.90KMar 31, 26-7000.03%
WELLS FARGO & COMPANY/MN10.76KMar 31, 26-21.17K0.03%
BNP PARIBAS ARBITRAGE, SNC10.38KMar 31, 26+3.60K0.03%
JANUS HENDERSON GROUP PLC10.30KMar 31, 26+10.30K0.03%
Verition Fund Management LLC10.22KMar 31, 26-47.35K0.03%
Aquatic Capital Management LLC10.15KMar 31, 26+10.15K0.03%
SUSQUEHANNA INTERNATIONAL GROUP, LLP9.49KMar 31, 26-67.04K0.03%
Virtus Investment Advisers, Inc.9.13KMar 31, 26+2210.03%
ACT CAPITAL MANAGEMENT, LLC9.00KMar 31, 26+9.00K0.03%
NEW YORK STATE COMMON RETIREMENT FUND9.00KMar 31, 26+4.70K0.03%
SEI INVESTMENTS CO8.99KMar 31, 26+1.33K0.03%
Toroso Investments, LLC8.88KMar 31, 26+8.88K0.03%
TEMA ETFS LLC8.88KMar 31, 26+8.88K0.03%
ACADIAN ASSET MANAGEMENT LLC8.82KMar 31, 26-39.79K0.03%
AMERICAN CENTURY COMPANIES INC8.73KMar 31, 26-3.51K0.03%
PROFUND ADVISORS LLC8.39KMar 31, 26-8260.02%
China Universal Asset Management Co., Ltd.7.97KMar 31, 26-7.35K0.02%
Brinker Capital Investments, LLC7.95KMar 31, 26+7.95K0.02%
State of New Jersey Common Pension Fund D7.67KMar 31, 26+7.67K0.02%
Police & Firemen's Retirement System of New Jersey7.52KMar 31, 26--0.02%
BRIDGEWAY CAPITAL MANAGEMENT, LLC7.50KMar 31, 26-2.50K0.02%
UBS ASSET MANAGEMENT AMERICAS INC7.24KMar 31, 26+7.14K0.02%
INTECH INVESTMENT MANAGEMENT LLC6.84KMar 31, 26-140.02%
GROUP ONE TRADING, L.P.6.25KMar 31, 26-3.18K0.02%
Vanguard Investments Australia, Ltd.6.10KMar 31, 26+6.10K0.02%
LOS ANGELES CAPITAL MANAGEMENT LLC5.60KMar 31, 26-4.76K0.02%
KLP KAPITALFORVALTNING AS4.90KMar 31, 26+4.90K0.01%
Russell Investments Group, Ltd.3.86KMar 31, 26+1.00K0.01%
SG Americas Securities, LLC3.39KMar 31, 26-1.38K0.01%
Rockefeller Capital Management L.P.3.22KMar 31, 26+2240.01%
Mirae Asset Global Investments Co., Ltd.2.34KMar 31, 26+1600.01%
Ameritas Investment Partners, Inc.2.31KMar 31, 26--0.01%
CWM, LLC1.77KMar 31, 26-120.01%
STRS OHIO1.60KMar 31, 26+9000.00%
NISA INVESTMENT ADVISORS, LLC1.59KMar 31, 26--0.00%
Tower Research Capital LLC (TRC)1.41KMar 31, 26-2.00K0.00%
SIMPLEX TRADING, LLC1.31KMar 31, 26-7.62K0.00%
GF FUND MANAGEMENT CO. LTD.1.01KMar 31, 26+1270.00%
Sterling Capital Management LLC949Mar 31, 26-6920.00%
KBC Group NV810Mar 31, 26+8100.00%
ROYAL BANK OF CANADA751Mar 31, 26-7810.00%
EverSource Wealth Advisors, LLC704Mar 31, 26+6790.00%
Zurcher Kantonalbank (Zurich Cantonalbank)470Mar 31, 26+4700.00%
GAMMA Investing LLC299Mar 31, 26--0.00%
US BANCORP \DE\284Mar 31, 26-280.00%
ADVISOR GROUP HOLDINGS, INC.269Mar 31, 26-77.33K0.00%
PNC FINANCIAL SERVICES GROUP, INC.207Mar 31, 26+110.00%
SIGNATUREFD, LLC179Mar 31, 26--0.00%
FIL Ltd178Mar 31, 26+1780.00%
Physician Wealth Advisors, Inc.109Mar 31, 26--0.00%
JONES FINANCIAL COMPANIES LLLP80Mar 31, 26--0.00%
Allworth Financial LP70Mar 31, 26+180.00%
Parallel Advisors, LLC61Mar 31, 26--0.00%
Larson Financial Group LLC49Mar 31, 26+490.00%
ROTHSCHILD INVESTMENT LLC24Mar 31, 26--0.00%
Versant Capital Management, Inc24Mar 31, 26+240.00%
Fortitude Family Office, LLC19Mar 31, 26+190.00%
Farther Finance Advisors, LLC9Mar 31, 26-10.00%
MAI Capital Management7Mar 31, 26+70.00%
True Wealth Design, LLC2Mar 31, 26--0.00%
IFP Advisors, Inc1Mar 31, 26--0.00%
JANE STREET GROUP, LLC--Mar 31, 26-86.58K--
AMALGAMATED BANK--Mar 31, 26-895--
Aster Capital Management (DIFC) Ltd--Mar 31, 26-265--
Trexquant Investment LP--Mar 31, 26-24.27K--
Graham Capital Management, L.P.--Mar 31, 26-11.25K--
Brevan Howard Capital Management LP--Mar 31, 26-25.66K--
Rafferty Asset Management, LLC--Mar 31, 26-8.11K--
Caitong International Asset Management Co., Ltd--Mar 31, 26-154--
AXQ CAPITAL, LP--Mar 31, 26-6.46K--
SBI Securities Co., Ltd.--Mar 31, 26-9--
ProShare Advisors LLC--Mar 31, 26-7.19K--
Daiwa Securities Group Inc.--Mar 31, 26-150--
BALYASNY ASSET MANAGEMENT L.P.--Mar 31, 26-119.73K--
FOX RUN MANAGEMENT, L.L.C.--Mar 31, 26-23.82K--
RENAISSANCE TECHNOLOGIES LLC--Mar 31, 26-32.64K--
Point72 Asset Management, L.P.--Mar 31, 26-680.61K--
GSA CAPITAL PARTNERS LLP--Mar 31, 26-19.30K--
VANGUARD GROUP INC1.82MDec 31, 25+140.45K5.41%
BALYASNY ASSET MANAGEMENT L.P.119.73KDec 31, 25+94.08K0.36%
BANK OF AMERICA CORP /DE/37.89KDec 31, 25+11.28K0.11%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM1.75KDec 31, 25+6890.01%
Global Retirement Partners, LLC19Dec 31, 25+190.00%
COMERICA BANK--Dec 31, 25-76--
Nuveen Asset Management, LLC14.47KDec 31, 24+14.47K0.04%

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