MBX
Next earnings: Aug 6, 2026 · Before open
Signal
Mixed11
Price
1
Move-8.23%Selling pressure
Volume
1
Volume1.1× avgNormal activity
Technical
1
RSIRSI 61Momentum positive
PRICE
Prev Close
35.36
Open
34.78
Day Range32.37 – 35.27
32.37
35.27
52W Range9.43 – 45.85
9.43
45.85
63% of range
VOLUME & SIZE
Avg Volume
573.1K
FUNDAMENTALS
P/E Ratio
-14.9x
Not profitable
EPS (TTM)
Div Yield
No dividend
Performance
1D
-8.23%
5D
-7.13%
1M
-1.55%
3M
-14.81%
6M
+30.90%
YTD
+2.89%
1Y
+204.69%
Best: 1Y (+204.69%)Worst: 3M (-14.81%)
Quick Read
TrendInsufficient MA data
Momentum
BEARISH
thin 0% gross margin
Valuation
FAIR
P/E not available
Health
MODERATE
CR 30.8 · FCF negative
Neutral
Key MetricsTTM
Market Cap$1.09B
Revenue TTM$0.00
Net Income TTM-$86.61M
Free Cash Flow-$79.81M
Gross Margin0.0%
Net Margin0.0%
Operating Margin0.0%
Return on Equity-24.5%
Return on Assets-19.1%
Debt / Equity0.00
Current Ratio30.79
EPS TTM$-1.86
Alpha SignalsFull Analysis →
What Moves This Stock

Clinical trial data readouts for MBX 2109 (Phase 2/3 efficacy, safety signals, dosing optimization)

FDA regulatory interactions (IND clearances, Fast Track/Orphan Drug designations, breakthrough therapy status)

Partnership announcements or licensing deals with large pharma (upfront payments, milestone structures, royalty rates)

Capital raises and cash runway updates (dilution concerns vs. funding adequacy for trial completion)

Macro Sensitivity
Economic Cycle

low - Clinical-stage biotech operations are largely insulated from GDP fluctuations. R&D spending continues regardless of economic conditions, and rare disease patient populations remain stable. However, financing environment sensitivity is high: during recessions, biotech IPO/follow-on markets contract, making capital raises more dilutive or impossible. The company's strong current ratio (32.95) provides buffer against near-term financing stress.

Interest Rates

Rising interest rates create multiple headwinds: (1) Higher discount rates compress NPV of distant future cash flows, particularly punishing pre-revenue biotechs with 5-10 year commercialization timelines; (2) Risk-free rate competition makes speculative growth equities less attractive relative to bonds; (3) Biotech sector correlation with Nasdaq growth indices amplifies rate-driven multiple compression. Cash holdings benefit from higher yields on treasury investments, but this is marginal relative to valuation impact. Historical data shows biotech indices decline 15-25% when 10-year yields rise 100bps.

Key Risks

Binary clinical trial risk: Phase 2/3 failure rates in endocrinology exceed 50%, and single negative readout can eliminate 70-90% of market value overnight

Regulatory pathway uncertainty: FDA approval timelines for novel peptide therapeutics average 8-12 years from IND to NDA, with evolving safety/efficacy standards for chronic hormone replacement

Reimbursement pressure: Payer scrutiny on high-cost rare disease therapies intensifying, with ICER cost-effectiveness reviews potentially limiting pricing power below $150K annual treatment cost thresholds

Investor Profile

growth - Pure clinical-stage speculation attracting biotech-specialized hedge funds, venture crossover funds, and retail momentum traders. The 261% one-year return and 168% six-month return indicate strong momentum/technical following. Institutional ownership likely concentrated among healthcare-focused funds (Perceptive Advisors, RTW Investments, RA Capital) willing to underwrite binary clinical risk for 3-5x return potential on approval. Zero dividend yield and negative cash flow eliminate income/value investors entirely. Volatility profile attracts options traders around data catalyst events.

Watch on Earnings
MBX 2109 Phase 2/3 trial enrollment pace and interim data timing announcementsQuarterly cash burn rate and projected cash runway (months of operations funded)Nasdaq Biotechnology Index (NBI) performance as sector sentiment proxy10-year Treasury yield (GS10) as primary valuation multiple driver for growth biotechs
Health Radar
3 strong3 concern
44/100
Liquidity
30.79Strong
Leverage
0.00Strong
Coverage
0.0xConcern
ROE
-24.5%Concern
ROIC
-22.5%Concern
Cash
$75MStrong
ANALYST COVERAGE7 analysts
BUY
+100.3%upside to target
L $18.00
Med $65.00consensus
H $88.00
Buy
7100%
7 Buy (100%)0 Hold (0%)0 Sell (0%)
Full report →
Stock Health
Composite Score
4 of 5 signals bullish
7/10
Technicals
RSI RangeRSI 61 — Bullish momentum
Volume
Volume FlowLean Distribution — selling pressure
Fundamentals
Last EarningsBeat estimates
Analyst ConsensusBuy
LiquidityCurrent Ratio 30.79 — healthy liquidity
Upcoming Events
EEarnings ReportMay 17, 2026
Tomorrow
DEx-Dividend DateAug 14, 2026
In 90 days
PDividend PaymentAug 27, 2026
In 103 days
Technicals
Technical SetupBULLISH
Technicals →

Trend

UptrendGolden Cross · 50D leads 200D by 19.7%

+2.9% vs SMA 50 · +23.2% vs SMA 200

Momentum

RSI61.0
Positive momentum, not extended
MACD+1.55
Above zero — bullish momentum · expanding
Market Position
Price Levels
52W High
$45.85+41.3%
EMA 50
$33.15+2.2%
Current
$32.45
EMA 200
$25.68-20.8%
52W Low
$9.43-70.9%
52-Week RangeMid-range
$9.4363th %ile$45.85
Squeeze SetupVolume-based
No Clear Setup

Volume distribution is neutral or leaning toward distribution. No compelling squeeze setup based on current money flow data.

20-Day Money Flow
Acc days:3
Dist days:5
Edge:+2 dist
Volume Context
Avg Vol (50D)573K
Recent Vol (5D)
1.0M+81%

Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.

Earnings & Analysts

ANALYST ESTIMATES

Consensus of 8 analysts
Analyst revisions:EPS↑ Revised Up

Analyst consensus estimates · Actuals replace estimates as reported

YearRevenue Est.Rev GthEPS Est.EPS GthRangeAnalysts
FY2025
$0-$2.47
±6%
High6
FY2026(current)
$0-$2.80
±10%
High8
FY2027
$0-$3.91
±12%
High8
Range confidence:Tight (high)ModerateWide (low)
🔥Beat 6 consecutive quarters
Earnings HistoryMBX
Last 7Q
+15.7%avg beat
Beat 6 of 7 quartersMissed 1 Estimates rising
-2%
Q4'24
+20%
Q1'25
+12%
Q2'25
+25%
Q3'25
+14%
Q4'25
+23%
Q1'26
+18%
Q2'26
Beat
Miss
Estimate
Deeper color = bigger beat/miss
* Negative EPS shown at reduced height
Insider Activity
SEC Filings →
2 Buys/4 SellsNet Selling
NET SELLERS$0 bought · $2.7M sold · 30d window
Azoulay SalomonChief Medical …
$575K
May 8
SELL
Azoulay SalomonChief Medical …
$2.1M
May 8
SELL
Azoulay SalomonChief Medical …
$7K
May 6
SELL
Hawryluk P. KentDir
$18K
May 6
SELL
Hawryluk P. KentDir
$526K
Mar 13
BUY
Hawryluk P. KentDir
$273K
Oct 20
BUY
Financials

INSTITUTIONAL OWNERSHIP

1
BlackRock, Inc.
2.9M
2
Aaron Wealth Advisors LLC
1.2M
3
UBS Group AG
347K
4
Candriam S.C.A.
294K
5
NORTHERN TRUST CORP
211K
6
Soleus Capital Management, L.P.
179K
7
VANGUARD FIDUCIARY TRUST CO
170K
8
Goelzer Investment Management, Inc.
164K
News & Activity

MBX News

20 articles · 4h ago

About

No company information available

PeersHealth Care(7 companies)
Screen sector →
SymbolPriceDay %Mkt CapP/ERev GrwMarginELO
MBX
$32.45-8.23%$1.1B1500
$66.13-5.07%$13.0B+12626.1%-14525.8%1500
$94.92-3.79%$12.6B+3288.2%-4239.0%1500
$523.69-3.00%$12.1B+43205.3%-3008.0%1500
$227.72-1.30%$11.7B+6554.5%-2868.8%1500
$57.90-0.86%$11.2B50.3+1459.3%147.7%1500
$76.67-3.79%$10.8B+2325815.3%-19.7%1500
Sector avg-3.72%50.3+398824.8%-4085.6%1500