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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 4.00M | Jun 30, 26 | -- | 9.87% |
| BVF INC/IL | 3.24M | Jun 30, 26 | +1.26M | 7.99% |
| ACORN CAPITAL ADVISORS, LLC | 2.84M | Jun 30, 26 | -- | 7.01% |
| StepStone Group LP | 2.66M | Jun 30, 26 | -- | 6.57% |
| ADAR1 Capital Management, LLC | 2.24M | Jun 30, 26 | -196.26K | 5.53% |
| Vivo Capital, LLC | 1.93M | Jun 30, 26 | -- | 4.76% |
| Vestal Point Capital, LP | 1.83M | Jun 30, 26 | -14.12K | 4.51% |
| BlackRock, Inc. | 1.50M | Jun 30, 26 | +1.45M | 3.70% |
| Trails Edge Capital Partners, LP | 1.44M | Jun 30, 26 | +1.44M | 3.55% |
| VANGUARD CAPITAL MANAGEMENT LLC | 1.44M | Jun 30, 26 | +854.56K | 3.55% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.20M | Jun 30, 26 | -- | 2.98% |
| CITADEL ADVISORS LLC | 1.19M | Jun 30, 26 | +1.15M | 2.93% |
| Sio Capital Management, LLC | 1.08M | Jun 30, 26 | -- | 2.66% |
| Prosight Management, LP | 978.99K | Jun 30, 26 | -1.18M | 2.42% |
| Logos Global Management LP | 963.86K | Jun 30, 26 | +963.86K | 2.38% |
| GEODE CAPITAL MANAGEMENT, LLC | 724.44K | Jun 30, 26 | +625.69K | 1.79% |
| NEA Management Company, LLC | 478.55K | Jun 30, 26 | -- | 1.18% |
| STATE STREET CORP | 463.66K | Jun 30, 26 | +450.20K | 1.14% |
| Ensign Peak Advisors, Inc | 431.63K | Jun 30, 26 | +431.63K | 1.07% |
| RENAISSANCE TECHNOLOGIES LLC | 358.74K | Jun 30, 26 | -18.51K | 0.89% |
| Sofinnova Investments, Inc. | 321.69K | Jun 30, 26 | +179.99K | 0.79% |
| Carlyle Group Inc. | 269.89K | Jun 30, 26 | -- | 0.67% |
| Affinity Asset Advisors, LLC | 240.96K | Jun 30, 26 | -- | 0.60% |
| Seven Fleet Capital Management LP | 240.96K | Jun 30, 26 | +240.96K | 0.60% |
| DV EQUITIES, LLC | 240.96K | Jun 30, 26 | +240.96K | 0.60% |
| NORTHERN TRUST CORP | 197.18K | Jun 30, 26 | +177.27K | 0.49% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 177.77K | Jun 30, 26 | +177.77K | 0.44% |
| VANGUARD FIDUCIARY TRUST CO | 165.18K | Jun 30, 26 | +121.81K | 0.41% |
| MARSHALL WACE, LLP | 159.88K | Jun 30, 26 | +123.44K | 0.39% |
| Rosalind Advisors, Inc. | 150.00K | Jun 30, 26 | -293.76K | 0.37% |
| Stonepine Capital Management, LLC | 130.68K | Jun 30, 26 | -1.89K | 0.32% |
| Longaeva Partners L.P. | 120.48K | Jun 30, 26 | +120.48K | 0.30% |
| TWO SIGMA INVESTMENTS, LP | 108.87K | Jun 30, 26 | +84.61K | 0.27% |
| BANK OF AMERICA CORP /DE/ | 106.32K | Jun 30, 26 | +106.32K | 0.26% |
| CANTOR FITZGERALD, L. P. | 100.01K | Jun 30, 26 | +114 | 0.25% |
| UBS Group AG | 99.60K | Jun 30, 26 | +96.21K | 0.25% |
| Rangeley Capital, LLC | 95.00K | Jun 30, 26 | -- | 0.23% |
| Aisling Capital Management LP | 88.61K | Jun 30, 26 | -- | 0.22% |
| Bank of New York Mellon Corp | 72.22K | Jun 30, 26 | +72.22K | 0.18% |
| Walleye Capital LLC | 71.10K | Jun 30, 26 | +71.10K | 0.18% |
| DIMENSIONAL FUND ADVISORS LP | 68.56K | Jun 30, 26 | +68.56K | 0.17% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 63.64K | Jun 30, 26 | +63.64K | 0.16% |
| Sixth Street Partners Management Company, L.P. | 63.64K | Jun 30, 26 | +63.64K | 0.16% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 50.29K | Jun 30, 26 | +34.00K | 0.12% |
| Shay Capital LLC | 50.00K | Jun 30, 26 | -82.22K | 0.12% |
| PRELUDE CAPITAL MANAGEMENT, LLC | 46.69K | Jun 30, 26 | +46.69K | 0.12% |
| Aldebaran Capital, LLC | 39.87K | Jun 30, 26 | -550 | 0.10% |
| WELLS FARGO & COMPANY/MN | 36.45K | Jun 30, 26 | +22.95K | 0.09% |
| Nuveen, LLC | 35.40K | Jun 30, 26 | +35.40K | 0.09% |
| BARCLAYS PLC | 31.72K | Jun 30, 26 | +6.72K | 0.08% |
| Verdad Advisers, LP | 28.66K | Jun 30, 26 | +28.66K | 0.07% |
| DEUTSCHE BANK AG\ | 25.56K | Jun 30, 26 | +25.56K | 0.06% |
| AMERICAN CENTURY COMPANIES INC | 23.08K | Jun 30, 26 | +23.08K | 0.06% |
| MORGAN STANLEY | 21.86K | Jun 30, 26 | +7.53K | 0.05% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 21.48K | Jun 30, 26 | +21.48K | 0.05% |
| RHUMBLINE ADVISERS | 21.00K | Jun 30, 26 | +21.00K | 0.05% |
| Jump Financial, LLC | 20.40K | Jun 30, 26 | +20.40K | 0.05% |
| BNP PARIBAS ARBITRAGE, SNC | 19.89K | Jun 30, 26 | +19.61K | 0.05% |
| NEW YORK STATE COMMON RETIREMENT FUND | 18.10K | Jun 30, 26 | +18.10K | 0.04% |
| XTX Topco Ltd | 16.97K | Jun 30, 26 | -17.16K | 0.04% |
| T. Rowe Price Investment Management, Inc. | 15.34K | Jun 30, 26 | +15.34K | 0.04% |
| Invesco Ltd. | 13.64K | Jun 30, 26 | +13.64K | 0.03% |
| CITIGROUP INC | 12.19K | Jun 30, 26 | +12.19K | 0.03% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 12.07K | Jun 30, 26 | +12.07K | 0.03% |
| Y-Intercept (Hong Kong) Ltd | 11.29K | Jun 30, 26 | +11.29K | 0.03% |
| JPMORGAN CHASE & CO | 10.91K | Jun 30, 26 | +10.87K | 0.03% |
| Police & Firemen's Retirement System of New Jersey | 10.32K | Jun 30, 26 | +10.32K | 0.03% |
| Legal & General Group Plc | 2.56K | Jun 30, 26 | +2.56K | 0.01% |
| Ameritas Investment Partners, Inc. | 2.38K | Jun 30, 26 | +2.38K | 0.01% |
| Russell Investments Group, Ltd. | 2.10K | Jun 30, 26 | +2.10K | 0.01% |
| Tower Research Capital LLC (TRC) | 1.61K | Jun 30, 26 | +1.61K | 0.00% |
| ROYAL BANK OF CANADA | 967 | Jun 30, 26 | +737 | 0.00% |
| Sterling Capital Management LLC | 528 | Jun 30, 26 | +528 | 0.00% |
| TRUST CO OF TOLEDO NA /OH/ | 136 | Jun 30, 26 | -- | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 90 | Jun 30, 26 | -- | 0.00% |
| FMR LLC | 89 | Jun 30, 26 | +89 | 0.00% |
| JANE STREET GROUP, LLC | -- | Jun 30, 26 | -26.81K | -- |
| Vanguard Global Advisers, LLC | -- | Jun 30, 26 | -745 | -- |
| GSA CAPITAL PARTNERS LLP | -- | Jun 30, 26 | -22.22K | -- |
| MILLENNIUM MANAGEMENT LLC | -- | Jun 30, 26 | -30.50K | -- |
| NewEdge Advisors, LLC | -- | Jun 30, 26 | -44.55K | -- |
| Foresite Capital Management VI LLC | -- | Jun 30, 26 | -1.45M | -- |
| HRT FINANCIAL LP | -- | Jun 30, 26 | -37.05K | -- |
| DV Trading LLC | -- | Jun 30, 26 | -240.96K | -- |
| VANGUARD GROUP INC | 626.59K | Dec 31, 25 | -51.63K | 1.55% |
| KOTLER KEVIN | 197.69K | Dec 31, 25 | +197.69K | 0.49% |
| TWO SIGMA ADVISERS, LP | 26.61K | Dec 31, 25 | -- | 0.07% |
Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data
