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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| Siren, L.L.C. | 3.31M | Jun 30, 26 | +400.00K | 7.01% |
| TCG Crossover Management, LLC | 3.03M | Jun 30, 26 | -- | 6.42% |
| Redmile Group, LLC | 2.16M | Jun 30, 26 | -- | 4.58% |
| Nantahala Capital Management, LLC | 1.35M | Jun 30, 26 | -800.00K | 2.85% |
| CITADEL ADVISORS LLC | 1.33M | Jun 30, 26 | +94.82K | 2.81% |
| Nextech Invest, Ltd. | 952.40K | Jun 30, 26 | -- | 2.02% |
| MILLENNIUM MANAGEMENT LLC | 909.28K | Jun 30, 26 | -164.91K | 1.93% |
| Ikarian Capital, LLC | 830.78K | Jun 30, 26 | -35.00K | 1.76% |
| TFG Asset Management GP Ltd | 764.26K | Jun 30, 26 | +134.09K | 1.62% |
| Soleus Capital Management, L.P. | 630.00K | Jun 30, 26 | +630.00K | 1.33% |
| BALYASNY ASSET MANAGEMENT L.P. | 610.98K | Jun 30, 26 | +610.98K | 1.29% |
| 5AM Venture Management, LLC | 476.20K | Jun 30, 26 | -- | 1.01% |
| GREAT POINT PARTNERS LLC | 450.00K | Jun 30, 26 | -570.49K | 0.95% |
| MORGAN STANLEY | 403.17K | Jun 30, 26 | +337.69K | 0.85% |
| AMERIPRISE FINANCIAL INC | 370.05K | Jun 30, 26 | +370.05K | 0.78% |
| JANE STREET GROUP, LLC | 369.15K | Jun 30, 26 | +268.22K | 0.78% |
| ADAR1 Capital Management, LLC | 338.37K | Jun 30, 26 | +166.22K | 0.72% |
| SummitTX Capital, L.P. | 326.65K | Jun 30, 26 | +326.65K | 0.69% |
| Schonfeld Strategic Advisors LLC | 269.35K | Jun 30, 26 | +269.35K | 0.57% |
| UBS Group AG | 243.15K | Jun 30, 26 | -3.79K | 0.51% |
| BlackRock, Inc. | 219.92K | Jun 30, 26 | +15.14K | 0.47% |
| BANK OF MONTREAL /CAN/ | 201.73K | Jun 30, 26 | -1.17K | 0.43% |
| BOOTHBAY FUND MANAGEMENT, LLC | 198.35K | Jun 30, 26 | -10.74K | 0.42% |
| Propel Bio Management, LLC | 191.73K | Jun 30, 26 | +191.73K | 0.41% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 184.52K | Jun 30, 26 | +69.24K | 0.39% |
| FRED ALGER MANAGEMENT, LLC | 177.00K | Jun 30, 26 | +177.00K | 0.37% |
| Qube Research & Technologies Ltd | 163.94K | Jun 30, 26 | +59.39K | 0.35% |
| Caption Management, LLC | 162.48K | Jun 30, 26 | +162.48K | 0.34% |
| BNP PARIBAS ARBITRAGE, SNC | 158.95K | Jun 30, 26 | +11.28K | 0.34% |
| GOLDMAN SACHS GROUP INC | 155.93K | Jun 30, 26 | +103.42K | 0.33% |
| HSBC HOLDINGS PLC | 122.83K | Jun 30, 26 | -- | 0.26% |
| TWO SIGMA INVESTMENTS, LP | 121.00K | Jun 30, 26 | +104.80K | 0.26% |
| Quadrature Capital Ltd | 118.13K | Jun 30, 26 | +118.13K | 0.25% |
| Squarepoint Ops LLC | 115.92K | Jun 30, 26 | +26.45K | 0.25% |
| XTX Topco Ltd | 107.58K | Jun 30, 26 | +1.58K | 0.23% |
| M28 Capital Management LP | 101.20K | Jun 30, 26 | -- | 0.21% |
| MARSHALL WACE, LLP | 72.04K | Jun 30, 26 | -97.58K | 0.15% |
| Birchview Capital, LP | 71.22K | Jun 30, 26 | +71.22K | 0.15% |
| Seven Fleet Capital Management LP | 60.11K | Jun 30, 26 | -96.65K | 0.13% |
| Ishara Investments LP | 55.35K | Jun 30, 26 | -85.15K | 0.12% |
| HRT FINANCIAL LP | 30.75K | Jun 30, 26 | +18.75K | 0.07% |
| GEODE CAPITAL MANAGEMENT, LLC | 29.54K | Jun 30, 26 | -- | 0.06% |
| Virtu Financial LLC | 25.64K | Jun 30, 26 | +25.64K | 0.05% |
| BANK OF AMERICA CORP /DE/ | 25.28K | Jun 30, 26 | -4.49K | 0.05% |
| Trexquant Investment LP | 23.84K | Jun 30, 26 | +23.84K | 0.05% |
| Verdad Advisers, LP | 20.40K | Jun 30, 26 | +20.40K | 0.04% |
| Scientech Research LLC | 19.13K | Jun 30, 26 | +19.13K | 0.04% |
| RENAISSANCE TECHNOLOGIES LLC | 16.93K | Jun 30, 26 | +16.93K | 0.04% |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 16.33K | Jun 30, 26 | +16.33K | 0.03% |
| Persistent Asset Partners Ltd | 15.17K | Jun 30, 26 | +15.17K | 0.03% |
| RAYMOND JAMES FINANCIAL INC | 15.00K | Jun 30, 26 | -10.00K | 0.03% |
| RHUMBLINE ADVISERS | 13.81K | Jun 30, 26 | -120 | 0.03% |
| CITIGROUP INC | 13.22K | Jun 30, 26 | +11.38K | 0.03% |
| AXQ CAPITAL, LP | 12.57K | Jun 30, 26 | +12.57K | 0.03% |
| SG Americas Securities, LLC | 12.06K | Jun 30, 26 | -274.64K | 0.03% |
| ACADIAN ASSET MANAGEMENT LLC | 11.84K | Jun 30, 26 | +7.02K | 0.03% |
| CenterBook Partners LP | 10.42K | Jun 30, 26 | +10.42K | 0.02% |
| China Universal Asset Management Co., Ltd. | 7.47K | Jun 30, 26 | -860 | 0.02% |
| JPMORGAN CHASE & CO | 3.86K | Jun 30, 26 | -3.77K | 0.01% |
| BARCLAYS PLC | 3.42K | Jun 30, 26 | +481 | 0.01% |
| JONES FINANCIAL COMPANIES LLLP | 2.50K | Jun 30, 26 | -- | 0.01% |
| Mirae Asset Global Investments Co., Ltd. | 2.10K | Jun 30, 26 | -349 | 0.00% |
| Tower Research Capital LLC (TRC) | 1.64K | Jun 30, 26 | -674 | 0.00% |
| Parallel Advisors, LLC | 1.30K | Jun 30, 26 | -- | 0.00% |
| Rialto Wealth Management, LLC | 1.02K | Jun 30, 26 | +1.02K | 0.00% |
| GF FUND MANAGEMENT CO. LTD. | 975 | Jun 30, 26 | -72 | 0.00% |
| Steward Partners Investment Advisory, LLC | 100 | Jun 30, 26 | -- | 0.00% |
| Rockefeller Capital Management L.P. | 45 | Jun 30, 26 | -- | 0.00% |
| Caitong International Asset Management Co., Ltd | 41 | Jun 30, 26 | +38 | 0.00% |
| SBI Securities Co., Ltd. | 28 | Jun 30, 26 | -- | 0.00% |
| Dynamic Technology Lab Private Ltd | -- | Jun 30, 26 | -10.49K | -- |
| SIMPLEX TRADING, LLC | -- | Jun 30, 26 | -612 | -- |
| Point72 Asset Management, L.P. | -- | Jun 30, 26 | -119.71K | -- |
| Jones Hill Capital LP | -- | Jun 30, 26 | -301.60K | -- |
| TWO SIGMA ADVISERS, LP | 15.90K | Dec 31, 25 | -26.70K | 0.03% |
| EHP Funds Inc. | -- | Dec 31, 25 | -10.67K | -- |
| Aquilo Capital Management, LLC | -- | Mar 31, 25 | -367.21K | -- |
| Nextech Invest Ltd. | 952.40K | Dec 31, 24 | -- | 2.02% |
| Consonance Capital Management LP | -- | Sep 30, 22 | -634.27K | -- |
Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data