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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 1.30M | Jun 30, 26 | +589.54K | 13.48% |
| BVF INC/IL | 1.25M | Jun 30, 26 | -- | 12.94% |
| Affinity Asset Advisors, LLC | 1.17M | Jun 30, 26 | +102.97K | 12.12% |
| BlackRock, Inc. | 1.12M | Jun 30, 26 | +889.97K | 11.60% |
| Samsara BioCapital, LLC | 1.06M | Jun 30, 26 | -- | 10.98% |
| Kynam Capital Management, LP | 872.56K | Jun 30, 26 | -- | 9.02% |
| ORBIMED ADVISORS LLC | 743.94K | Jun 30, 26 | -57.20K | 7.69% |
| BALYASNY ASSET MANAGEMENT L.P. | 711.16K | Jun 30, 26 | +245.37K | 7.35% |
| VANGUARD CAPITAL MANAGEMENT LLC | 694.22K | Jun 30, 26 | -26.22K | 7.17% |
| EVENTIDE ASSET MANAGEMENT, LLC | 585.26K | Jun 30, 26 | -130.04K | 6.05% |
| Velan Capital Investment Management LP | 512.16K | Jun 30, 26 | -- | 5.29% |
| Woodline Partners LP | 458.03K | Jun 30, 26 | +588 | 4.73% |
| ADAR1 Capital Management, LLC | 404.01K | Jun 30, 26 | -120.43K | 4.17% |
| GEODE CAPITAL MANAGEMENT, LLC | 389.69K | Jun 30, 26 | +218.31K | 4.03% |
| ACADIAN ASSET MANAGEMENT LLC | 373.84K | Jun 30, 26 | +38.03K | 3.86% |
| MILLENNIUM MANAGEMENT LLC | 365.97K | Jun 30, 26 | +155.59K | 3.78% |
| STATE STREET CORP | 305.98K | Jun 30, 26 | +253.86K | 3.16% |
| Merck & Co., Inc. | 272.35K | Jun 30, 26 | +272.35K | 2.81% |
| ACUTA CAPITAL PARTNERS, LLC | 270.25K | Jun 30, 26 | +826 | 2.79% |
| AMERIPRISE FINANCIAL INC | 244.67K | Jun 30, 26 | +244.67K | 2.53% |
| Point72 Asset Management, L.P. | 237.83K | Jun 30, 26 | -454.28K | 2.46% |
| KVP Capital Advisors, LP | 226.57K | Jun 30, 26 | -- | 2.34% |
| UBS Group AG | 208.51K | Jun 30, 26 | -184.36K | 2.15% |
| TWO SIGMA INVESTMENTS, LP | 201.69K | Jun 30, 26 | +136.51K | 2.08% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 197.56K | Jun 30, 26 | +197.56K | 2.04% |
| MARSHALL WACE, LLP | 175.25K | Jun 30, 26 | -47.39K | 1.81% |
| Nuveen, LLC | 168.00K | Jun 30, 26 | +168.00K | 1.74% |
| JPMORGAN CHASE & CO | 159.63K | Jun 30, 26 | +159.63K | 1.65% |
| Seven Fleet Capital Management LP | 159.12K | Jun 30, 26 | +159.12K | 1.64% |
| GOLDMAN SACHS GROUP INC | 149.22K | Jun 30, 26 | +122.03K | 1.54% |
| NORTHERN TRUST CORP | 125.93K | Jun 30, 26 | +92.77K | 1.30% |
| Qube Research & Technologies Ltd | 106.61K | Jun 30, 26 | +106.61K | 1.10% |
| VANGUARD FIDUCIARY TRUST CO | 104.23K | Jun 30, 26 | +9.39K | 1.08% |
| CITADEL ADVISORS LLC | 101.97K | Jun 30, 26 | -15.57K | 1.05% |
| MACKENZIE FINANCIAL CORP | 94.77K | Jun 30, 26 | +94.77K | 0.98% |
| RENAISSANCE TECHNOLOGIES LLC | 86.32K | Jun 30, 26 | -11.50K | 0.89% |
| Invesco Ltd. | 57.30K | Jun 30, 26 | +40.14K | 0.59% |
| Y-Intercept (Hong Kong) Ltd | 55.88K | Jun 30, 26 | +55.88K | 0.58% |
| Squarepoint Ops LLC | 55.54K | Jun 30, 26 | +55.54K | 0.57% |
| XTX Topco Ltd | 52.17K | Jun 30, 26 | +43.97K | 0.54% |
| Sixth Street Partners Management Company, L.P. | 49.30K | Jun 30, 26 | +49.30K | 0.51% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 49.30K | Jun 30, 26 | +38.73K | 0.51% |
| Sigma Planning Corp | 45.02K | Jun 30, 26 | +32.50K | 0.47% |
| Bank of New York Mellon Corp | 41.37K | Jun 30, 26 | +41.37K | 0.43% |
| BARCLAYS PLC | 36.95K | Jun 30, 26 | +36.81K | 0.38% |
| BANK OF AMERICA CORP /DE/ | 36.14K | Jun 30, 26 | +17.27K | 0.37% |
| Fisher Asset Management, LLC | 35.30K | Jun 30, 26 | -- | 0.36% |
| Elmind Capital, LP | 32.04K | Jun 30, 26 | +32.04K | 0.33% |
| D. E. Shaw & Co., Inc. | 30.13K | Jun 30, 26 | +30.13K | 0.31% |
| Trexquant Investment LP | 27.64K | Jun 30, 26 | -6.71K | 0.29% |
| BNP PARIBAS ARBITRAGE, SNC | 27.38K | Jun 30, 26 | +27.27K | 0.28% |
| RHUMBLINE ADVISERS | 20.63K | Jun 30, 26 | +20.63K | 0.21% |
| GSA CAPITAL PARTNERS LLP | 19.75K | Jun 30, 26 | -6.07K | 0.20% |
| SEI INVESTMENTS CO | 16.39K | Jun 30, 26 | +16.39K | 0.17% |
| EAM Investors, LLC | 16.23K | Jun 30, 26 | +16.23K | 0.17% |
| DEUTSCHE BANK AG\ | 15.56K | Jun 30, 26 | +15.56K | 0.16% |
| RBF Capital, LLC | 15.27K | Jun 30, 26 | -- | 0.16% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 13.60K | Jun 30, 26 | +13.60K | 0.14% |
| WELLS FARGO & COMPANY/MN | 13.54K | Jun 30, 26 | +13.54K | 0.14% |
| MORGAN STANLEY | 12.36K | Jun 30, 26 | +1.83K | 0.13% |
| WELLINGTON MANAGEMENT GROUP LLP | 10.80K | Jun 30, 26 | +10.80K | 0.11% |
| MetLife Investment Management, LLC | 9.40K | Jun 30, 26 | +9.40K | 0.10% |
| Walleye Capital LLC | 9.31K | Jun 30, 26 | +9.31K | 0.10% |
| Integrated Quantitative Investments LLC | 8.94K | Jun 30, 26 | +8.94K | 0.09% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 8.43K | Jun 30, 26 | -76.48K | 0.09% |
| Lighthouse Investment Partners, LLC | 8.37K | Jun 30, 26 | +8.37K | 0.09% |
| CITIGROUP INC | 7.46K | Jun 30, 26 | -11.39K | 0.08% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 7.31K | Jun 30, 26 | +7.31K | 0.08% |
| ALLIANCEBERNSTEIN L.P. | 7.30K | Jun 30, 26 | +7.30K | 0.08% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 7.00K | Jun 30, 26 | +7.00K | 0.07% |
| Persistent Asset Partners Ltd | 6.57K | Jun 30, 26 | -842 | 0.07% |
| Verdad Advisers, LP | 6.40K | Jun 30, 26 | +6.40K | 0.07% |
| HSBC HOLDINGS PLC | 6.23K | Jun 30, 26 | +6.23K | 0.06% |
| NEW YORK STATE COMMON RETIREMENT FUND | 5.60K | Jun 30, 26 | +5.60K | 0.06% |
| Vanguard Global Advisers, LLC | 5.45K | Jun 30, 26 | -1.74K | 0.06% |
| Police & Firemen's Retirement System of New Jersey | 4.70K | Jun 30, 26 | +4.70K | 0.05% |
| Legal & General Group Plc | 3.46K | Jun 30, 26 | +3.46K | 0.04% |
| State of Wyoming | 1.62K | Jun 30, 26 | +1.62K | 0.02% |
| Ameritas Investment Partners, Inc. | 1.45K | Jun 30, 26 | +1.45K | 0.01% |
| FMR LLC | 1.34K | Jun 30, 26 | +289 | 0.01% |
| Russell Investments Group, Ltd. | 1.27K | Jun 30, 26 | +1.27K | 0.01% |
| FNY Investment Advisers, LLC | 1.00K | Jun 30, 26 | -- | 0.01% |
| Tower Research Capital LLC (TRC) | 866 | Jun 30, 26 | +866 | 0.01% |
| ROYAL BANK OF CANADA | 687 | Jun 30, 26 | +687 | 0.01% |
| Owl Creek Wealth Partners LLC | 491 | Jun 30, 26 | -- | 0.01% |
| Sterling Capital Management LLC | 281 | Jun 30, 26 | +281 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 220 | Jun 30, 26 | +220 | 0.00% |
| Quantbot Technologies LP | 201 | Jun 30, 26 | +201 | 0.00% |
| Physician Wealth Advisors, Inc. | 182 | Jun 30, 26 | -- | 0.00% |
| MERCER GLOBAL ADVISORS INC /ADV | 112 | Jun 30, 26 | +112 | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 100 | Jun 30, 26 | -1.18K | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | 62 | Jun 30, 26 | -- | 0.00% |
| Avion Wealth | 46 | Jun 30, 26 | -26 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | 44 | Jun 30, 26 | -- | 0.00% |
| HighMark Wealth Management LLC | 23 | Jun 30, 26 | -- | 0.00% |
| SRS Capital Advisors, Inc. | 16 | Jun 30, 26 | -25 | 0.00% |
| FIFTH THIRD BANCORP | 2 | Jun 30, 26 | -- | 0.00% |
| Steward Partners Investment Advisory, LLC | 2 | Jun 30, 26 | +2 | 0.00% |
| Optiver Holding B.V. | 2 | Jun 30, 26 | +2 | 0.00% |
| Hudson Bay Capital Management LP | -- | Jun 30, 26 | -14.77K | -- |
| Jump Financial, LLC | -- | Jun 30, 26 | -12.38K | -- |
| Brevan Howard Capital Management LP | -- | Jun 30, 26 | -18.79K | -- |
| RA CAPITAL MANAGEMENT, L.P. | -- | Jun 30, 26 | -715.31K | -- |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | -- | Jun 30, 26 | -200.00K | -- |
| Opaleye Management Inc. | -- | Jun 30, 26 | -190.67K | -- |
| StemPoint Capital LP | -- | Jun 30, 26 | -23.30K | -- |
| Eversept Partners, LP | -- | Jun 30, 26 | -73.16K | -- |
| OMERS ADMINISTRATION Corp | -- | Jun 30, 26 | -8.70K | -- |
| SIMPLEX TRADING, LLC | -- | Jun 30, 26 | -62 | -- |
| State of Tennessee, Treasury Department | -- | Jun 30, 26 | -7.40K | -- |
| Burkehill Global Management, LP | -- | Jun 30, 26 | -71.53K | -- |
| AQR CAPITAL MANAGEMENT LLC | -- | Jun 30, 26 | -8.61K | -- |
| JANE STREET GROUP, LLC | -- | Jun 30, 26 | -27.76K | -- |
| CWM, LLC | 983 | Mar 31, 26 | -516 | 0.01% |
| VANGUARD GROUP INC | 375.79K | Dec 31, 25 | -3.31M | 3.88% |
| TWO SIGMA ADVISERS, LP | 17.58K | Dec 31, 25 | -221.82K | 0.18% |
| COMERICA BANK | 3 | Dec 31, 25 | -46 | 0.00% |
| Point72 Asia (Singapore) Pte. Ltd. | 31.03K | Sep 30, 25 | -30.04K | 0.32% |
| Cubist Systematic Strategies, LLC | 10 | Sep 30, 25 | -6.07K | 0.00% |
| Accredited Wealth Management, LLC | 5 | Sep 30, 25 | -995 | 0.00% |
| Aquilo Capital Management, LLC | -- | Mar 31, 25 | -498 | -- |
| Nuveen Asset Management, LLC | 1.32M | Dec 31, 24 | +124.15K | 13.68% |
| PEAK6 Investments LLC | 11.31K | Sep 30, 24 | +11.31K | 0.12% |
| BlackRock Inc. | 6.91M | Jun 30, 24 | +1.21M | 71.41% |
| Point72 Middle East FZE | 1.80K | Dec 31, 23 | +1.80K | 0.02% |
| PUTNAM INVESTMENTS LLC | -- | Dec 31, 23 | -68.39K | -- |
| Ergoteles LLC | -- | Sep 30, 23 | -11.69K | -- |
| Tekla Capital Management LLC | 98.35K | Jun 30, 23 | -- | 1.02% |
| Personal Capital Advisors Corp | 11.20K | Dec 31, 22 | -- | 0.12% |
| American Portfolios Advisors | 10.00K | Sep 30, 22 | -- | 0.10% |
| FourThought Financial, LLC | 2.16K | Sep 30, 22 | -- | 0.02% |
| IndexIQ Advisors LLC | 48.93K | Mar 31, 22 | +48.93K | 0.51% |
| PARAMETRIC PORTFOLIO ASSOCIATES LLC | 11.46K | Mar 31, 22 | -11.75K | 0.12% |
| Amalgamated Financial Corp. | 5.38K | Mar 31, 22 | +5.38K | 0.06% |
| FIRST QUADRANT LLC/CA | -- | Mar 31, 22 | -6.10K | -- |
| Marshall Wace North America L.P. | -- | Sep 30, 21 | -43.76K | -- |
| VV Manager LLC | 365.66K | Jun 30, 20 | -99.21K | 3.78% |
| Advisor Group, Inc. | 200 | Dec 31, 19 | -- | 0.00% |
Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data
