Spyre Therapeutics, Inc.(SYRE)

$74.92▼-0.73 (-0.97%)

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Spyre Therapeutics, Inc.(SYRE)

NASDAQ

$74.92▼-0.73 (-0.97%)

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SYRE(SYRE)

SYRE

Overview Intelligence Chart Fundamentals Key Metrics Earnings Growth Analysts Financials Insiders Institutional

Institutional Ownership

Top 270 Institutional Holders

Holder	Shares	Date	Change	% Held
FMR LLC	11.78M	Mar 31, 26	+142.21K	19.50%
BlackRock, Inc.	5.52M	Mar 31, 26	-880	9.14%
RTW INVESTMENTS, LP	4.17M	Mar 31, 26	--	6.91%
Fairmount Funds Management LLC	4.02M	Mar 31, 26	--	6.65%
PERCEPTIVE ADVISORS LLC	3.78M	Mar 31, 26	+714.00K	6.26%
VR Adviser, LLC	3.69M	Mar 31, 26	--	6.10%
DRIEHAUS CAPITAL MANAGEMENT LLC	2.79M	Mar 31, 26	-91.64K	4.62%
STATE STREET CORP	2.61M	Mar 31, 26	+344.19K	4.32%
Paradigm Biocapital Advisors LP	1.96M	Mar 31, 26	+490.00K	3.24%
COMMODORE CAPITAL LP	1.91M	Mar 31, 26	-475.87K	3.17%
TCG Crossover Management, LLC	1.90M	Mar 31, 26	--	3.15%
TANG CAPITAL MANAGEMENT LLC	1.89M	Mar 31, 26	--	3.13%
WELLINGTON MANAGEMENT GROUP LLP	1.82M	Mar 31, 26	+275.53K	3.02%
Capital International Investors	1.75M	Mar 31, 26	-1.75M	2.89%
GEODE CAPITAL MANAGEMENT, LLC	1.72M	Mar 31, 26	+61.77K	2.85%
JANUS HENDERSON GROUP PLC	1.66M	Mar 31, 26	-172.84K	2.74%
RA CAPITAL MANAGEMENT, L.P.	1.62M	Mar 31, 26	--	2.68%
PRICE T ROWE ASSOCIATES INC /MD/	1.60M	Mar 31, 26	-3.15K	2.65%
Affinity Asset Advisors, LLC	1.28M	Mar 31, 26	-153.46K	2.12%
BAKER BROS. ADVISORS LP	1.00M	Mar 31, 26	--	1.66%
JPMORGAN CHASE & CO	979.30K	Mar 31, 26	+916.35K	1.62%
BRAIDWELL LP	932.82K	Mar 31, 26	-701.79K	1.54%
FRANKLIN RESOURCES INC	882.83K	Mar 31, 26	-226.44K	1.46%
Caligan Partners LP	878.13K	Mar 31, 26	+878.13K	1.45%
Siren, L.L.C.	818.60K	Mar 31, 26	--	1.36%
Polar Capital Holdings Plc	792.85K	Mar 31, 26	+52.52K	1.31%
UBS Group AG	671.24K	Mar 31, 26	-9.33K	1.11%
Capital World Investors	666.56K	Mar 31, 26	+466.39K	1.10%
EMERALD ADVISERS, LLC	613.37K	Mar 31, 26	-22.74K	1.02%
Candriam S.C.A.	610.28K	Mar 31, 26	+184.75K	1.01%
NORTHERN TRUST CORP	578.91K	Mar 31, 26	+17.88K	0.96%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	562.65K	Mar 31, 26	-11.97K	0.93%
Pictet Asset Management Holding SA	491.65K	Mar 31, 26	-422.31K	0.81%
VANGUARD FIDUCIARY TRUST CO	464.65K	Mar 31, 26	+464.65K	0.77%
EMERALD MUTUAL FUND ADVISERS TRUST	408.11K	Mar 31, 26	-4.26K	0.68%
SAMLYN CAPITAL, LLC	396.66K	Mar 31, 26	+396.66K	0.66%
Blackstone Inc.	292.85K	Mar 31, 26	-208.15K	0.48%
VICTORY CAPITAL MANAGEMENT INC	292.13K	Mar 31, 26	+146.05K	0.48%
GOLDMAN SACHS GROUP INC	269.94K	Mar 31, 26	-5.13K	0.45%
Woodline Partners LP	265.89K	Mar 31, 26	--	0.44%
MORGAN STANLEY	246.72K	Mar 31, 26	+63.98K	0.41%
UBS ASSET MANAGEMENT AMERICAS INC	207.31K	Mar 31, 26	+145.10K	0.34%
BOOTHBAY FUND MANAGEMENT, LLC	193.03K	Mar 31, 26	+193.03K	0.32%
Bank of New York Mellon Corp	191.40K	Mar 31, 26	-1.44K	0.32%
SILVERARC CAPITAL MANAGEMENT, LLC	186.62K	Mar 31, 26	-1.12K	0.31%
FIRST TRUST ADVISORS LP	178.39K	Mar 31, 26	+178.39K	0.30%
Universal- Beteiligungs- und Servicegesellschaft mbH	170.38K	Mar 31, 26	-830	0.28%
StemPoint Capital LP	167.61K	Mar 31, 26	+135.23K	0.28%
AMERIPRISE FINANCIAL INC	159.22K	Mar 31, 26	+120.96K	0.26%
Nuveen, LLC	153.90K	Mar 31, 26	+2.92K	0.25%
Ensign Peak Advisors, Inc	148.54K	Mar 31, 26	+148.54K	0.25%
MILLENNIUM MANAGEMENT LLC	146.64K	Mar 31, 26	+70.44K	0.24%
HighVista Strategies LLC	146.26K	Mar 31, 26	-41.94K	0.24%
MARSHALL WACE, LLP	139.26K	Mar 31, 26	+139.26K	0.23%
TD ASSET MANAGEMENT INC	137.39K	Mar 31, 26	-12.43K	0.23%
Invesco Ltd.	132.39K	Mar 31, 26	-18.54K	0.22%
DEUTSCHE BANK AG\	129.24K	Mar 31, 26	+7.30K	0.21%
ARMISTICE CAPITAL, LLC	120.93K	Mar 31, 26	-75.50K	0.20%
MANUFACTURERS LIFE INSURANCE COMPANY, THE	112.84K	Mar 31, 26	-16.17K	0.19%
CITADEL ADVISORS LLC	108.14K	Mar 31, 26	+44.23K	0.18%
SEVEN GRAND MANAGERS, LLC	100.00K	Mar 31, 26	--	0.17%
B Group, Inc.	100.00K	Mar 31, 26	--	0.17%
F/M Investments LLC	99.46K	Mar 31, 26	-4.26K	0.16%
Swiss National Bank	96.50K	Mar 31, 26	--	0.16%
ExodusPoint Capital Management, LP	87.06K	Mar 31, 26	+49.19K	0.14%
RHUMBLINE ADVISERS	85.12K	Mar 31, 26	+2.17K	0.14%
MERCER GLOBAL ADVISORS INC /ADV	71.09K	Mar 31, 26	-35.23K	0.12%
ALLIANCEBERNSTEIN L.P.	70.90K	Mar 31, 26	+3.40K	0.12%
Rockefeller Capital Management L.P.	64.00K	Mar 31, 26	+63.45K	0.11%
ALPS ADVISORS INC	63.94K	Mar 31, 26	+231	0.11%
SCHRODER INVESTMENT MANAGEMENT GROUP	63.68K	Mar 31, 26	+2.11K	0.11%
HealthInvest Partners AB	62.73K	Mar 31, 26	+62.73K	0.10%
PRUDENTIAL FINANCIAL INC	59.55K	Mar 31, 26	+59.55K	0.10%
FRED ALGER MANAGEMENT, LLC	59.45K	Mar 31, 26	+59.45K	0.10%
Rafferty Asset Management, LLC	56.92K	Mar 31, 26	+3.51K	0.09%
BALYASNY ASSET MANAGEMENT L.P.	55.48K	Mar 31, 26	-17.99K	0.09%
VOYA INVESTMENT MANAGEMENT LLC	53.97K	Mar 31, 26	+26.69K	0.09%
Susquehanna Portfolio Strategies, LLC	53.10K	Mar 31, 26	--	0.09%
DIMENSIONAL FUND ADVISORS LP	47.70K	Mar 31, 26	-29.59K	0.08%
BARCLAYS PLC	45.79K	Mar 31, 26	-136.74K	0.08%
Legal & General Group Plc	44.79K	Mar 31, 26	-11.66K	0.07%
MetLife Investment Management, LLC	38.41K	Mar 31, 26	+396	0.06%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	36.32K	Mar 31, 26	+1.18K	0.06%
VANGUARD ASSET MANAGEMENT, Ltd	33.23K	Mar 31, 26	+33.23K	0.06%
WELLS FARGO & COMPANY/MN	33.21K	Mar 31, 26	-49.21K	0.05%
Vanguard Global Advisers, LLC	31.14K	Mar 31, 26	+31.14K	0.05%
SUSQUEHANNA INTERNATIONAL GROUP, LLP	28.96K	Mar 31, 26	+22.85K	0.05%
Cinctive Capital Management LP	27.43K	Mar 31, 26	-8.51K	0.05%
STATE OF WISCONSIN INVESTMENT BOARD	26.52K	Mar 31, 26	-729	0.04%
PROFUND ADVISORS LLC	26.04K	Mar 31, 26	+5.45K	0.04%
Waverly Advisors, LLC	25.97K	Mar 31, 26	+12	0.04%
TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY	25.80K	Mar 31, 26	--	0.04%
XTX Topco Ltd	24.43K	Mar 31, 26	+24.43K	0.04%
NEW YORK STATE COMMON RETIREMENT FUND	22.27K	Mar 31, 26	+3.10K	0.04%
Ellsworth Advisors, LLC	21.96K	Mar 31, 26	+21.96K	0.04%
AQR CAPITAL MANAGEMENT LLC	20.87K	Mar 31, 26	+3.05K	0.03%
RAYMOND JAMES FINANCIAL INC	19.75K	Mar 31, 26	+19.75K	0.03%
Assenagon Asset Management S.A.	18.65K	Mar 31, 26	-3.49K	0.03%
BNP PARIBAS ARBITRAGE, SNC	18.63K	Mar 31, 26	+6.79K	0.03%
Police & Firemen's Retirement System of New Jersey	18.36K	Mar 31, 26	--	0.03%
Global Endowment Management, LP	18.18K	Mar 31, 26	--	0.03%
KENNEDY CAPITAL MANAGEMENT LLC	16.87K	Mar 31, 26	+16.87K	0.03%
State of New Jersey Common Pension Fund D	16.72K	Mar 31, 26	+22	0.03%
INTECH INVESTMENT MANAGEMENT LLC	16.44K	Mar 31, 26	-1.83K	0.03%
Creative Planning	15.49K	Mar 31, 26	+15.49K	0.03%
Zurcher Kantonalbank (Zurich Cantonalbank)	13.96K	Mar 31, 26	+2.79K	0.02%
China Universal Asset Management Co., Ltd.	13.94K	Mar 31, 26	+1.29K	0.02%
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM	13.90K	Mar 31, 26	+4.88K	0.02%
ProShare Advisors LLC	13.50K	Mar 31, 26	-2.49K	0.02%
Arizona State Retirement System	13.44K	Mar 31, 26	-359	0.02%
SG Americas Securities, LLC	13.40K	Mar 31, 26	-9.95K	0.02%
Vanguard Investments Australia, Ltd.	12.81K	Mar 31, 26	+12.81K	0.02%
BROWN ADVISORY INC	12.40K	Mar 31, 26	+12.40K	0.02%
CITIGROUP INC	12.01K	Mar 31, 26	-88.05K	0.02%
KLP KAPITALFORVALTNING AS	10.90K	Mar 31, 26	+500	0.02%
Russell Investments Group, Ltd.	9.93K	Mar 31, 26	+4.38K	0.02%
Carlyle Group Inc.	9.62K	Mar 31, 26	--	0.02%
Man Group plc	9.55K	Mar 31, 26	+9.55K	0.02%
MARTINGALE ASSET MANAGEMENT L P	9.08K	Mar 31, 26	+2.15K	0.02%
SEI INVESTMENTS CO	8.97K	Mar 31, 26	+2.86K	0.01%
Tower Research Capital LLC (TRC)	8.79K	Mar 31, 26	+8.37K	0.01%
Bridgefront Capital, LLC	8.65K	Mar 31, 26	+8.65K	0.01%
TUDOR INVESTMENT CORP ET AL	8.36K	Mar 31, 26	-1.76K	0.01%
RWC Asset Management LLP	8.17K	Mar 31, 26	+8.17K	0.01%
Virtus Investment Advisers, Inc.	8.11K	Mar 31, 26	+197	0.01%
Virtu Financial LLC	8.09K	Mar 31, 26	+8.09K	0.01%
CAPSTONE INVESTMENT ADVISORS, LLC	7.54K	Mar 31, 26	+7.54K	0.01%
E Fund Management Co., Ltd.	7.16K	Mar 31, 26	+7.16K	0.01%
Scientech Research LLC	7.09K	Mar 31, 26	+7.09K	0.01%
TWO SIGMA SECURITIES, LLC	6.85K	Mar 31, 26	+6.85K	0.01%
AlphaCentric Advisors LLC	6.63K	Mar 31, 26	+6.63K	0.01%
XPONANCE, INC.	6.45K	Mar 31, 26	+6.45K	0.01%
TEACHER RETIREMENT SYSTEM OF TEXAS	6.28K	Mar 31, 26	-893	0.01%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.	6.14K	Mar 31, 26	-7.58K	0.01%
High Net Worth Advisory Group LLC	6.00K	Mar 31, 26	+6.00K	0.01%
LOS ANGELES CAPITAL MANAGEMENT LLC	5.86K	Mar 31, 26	-7.02K	0.01%
Ameritas Investment Partners, Inc.	5.59K	Mar 31, 26	--	0.01%
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	5.20K	Mar 31, 26	+5.20K	0.01%
Persistent Asset Partners Ltd	4.80K	Mar 31, 26	+2.56K	0.01%
DeepCurrents Investment Group LLC	4.74K	Mar 31, 26	+4.74K	0.01%
Quantinno Capital Management LP	4.56K	Mar 31, 26	+4.56K	0.01%
STRS OHIO	4.50K	Mar 31, 26	+4.50K	0.01%
Vanguard Personalized Indexing Management, LLC	4.40K	Mar 31, 26	+4.40K	0.01%
PRINCIPAL FINANCIAL GROUP INC	4.30K	Mar 31, 26	+4.30K	0.01%
Mirae Asset Global Investments Co., Ltd.	4.10K	Mar 31, 26	+327	0.01%
Union Bancaire Privee, UBP SA	3.88K	Mar 31, 26	+3.88K	0.01%
ROYAL BANK OF CANADA	3.25K	Mar 31, 26	+1.26K	0.01%
ABS Direct Equity Fund LLC	2.80K	Mar 31, 26	+2.80K	0.00%
EverSource Wealth Advisors, LLC	2.34K	Mar 31, 26	+2.27K	0.00%
CWM, LLC	2.10K	Mar 31, 26	+135	0.00%
NISA INVESTMENT ADVISORS, LLC	1.92K	Mar 31, 26	+1.21K	0.00%
GF FUND MANAGEMENT CO. LTD.	1.74K	Mar 31, 26	+220	0.00%
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	1.59K	Mar 31, 26	--	0.00%
KBC Group NV	1.37K	Mar 31, 26	+1.37K	0.00%
Sterling Capital Management LLC	1.05K	Mar 31, 26	-559	0.00%
Patient Square Capital LP	1.00K	Mar 31, 26	-149.00K	0.00%
GROUP ONE TRADING, L.P.	901	Mar 31, 26	+501	0.00%
BNP Paribas Asset Management Holding S.A.	888	Mar 31, 26	+232	0.00%
Neo Ivy Capital Management	598	Mar 31, 26	-17.66K	0.00%
Kemnay Advisory Services Inc.	574	Mar 31, 26	+574	0.00%
CLEAR STREET MARKETS LLC	562	Mar 31, 26	+562	0.00%
GAMMA Investing LLC	523	Mar 31, 26	+193	0.00%
ADVISOR GROUP HOLDINGS, INC.	498	Mar 31, 26	+131	0.00%
Optiver Holding B.V.	288	Mar 31, 26	+48	0.00%
Caitong International Asset Management Co., Ltd	286	Mar 31, 26	+286	0.00%
Delos Wealth Advisors, LLC	250	Mar 31, 26	+250	0.00%
Smartleaf Asset Management LLC	157	Mar 31, 26	+157	0.00%
QUADRANT CAPITAL GROUP LLC	146	Mar 31, 26	+146	0.00%
PNC FINANCIAL SERVICES GROUP, INC.	123	Mar 31, 26	+37	0.00%
Allworth Financial LP	117	Mar 31, 26	+59	0.00%
ROTHSCHILD INVESTMENT LLC	99	Mar 31, 26	+17	0.00%
US BANCORP \DE\	97	Mar 31, 26	+87	0.00%
Quantbot Technologies LP	88	Mar 31, 26	+88	0.00%
Farther Finance Advisors, LLC	74	Mar 31, 26	+37	0.00%
SIGNATUREFD, LLC	70	Mar 31, 26	--	0.00%
Larson Financial Group LLC	36	Mar 31, 26	-108	0.00%
Parkside Financial Bank & Trust	35	Mar 31, 26	--	0.00%
Parallel Advisors, LLC	32	Mar 31, 26	+32	0.00%
IFP Advisors, Inc	24	Mar 31, 26	--	0.00%
SRS Capital Advisors, Inc.	18	Mar 31, 26	+18	0.00%
Bare Financial Services, Inc	16	Mar 31, 26	+16	0.00%
MAI Capital Management	13	Mar 31, 26	+13	0.00%
FIFTH THIRD BANCORP	5	Mar 31, 26	+5	0.00%
SBI Securities Co., Ltd.	5	Mar 31, 26	--	0.00%
MASSMUTUAL TRUST CO FSB/ADV	3	Mar 31, 26	+3	0.00%
TWIN PEAKS WEALTH ADVISORS, LLC	3	Mar 31, 26	+3	0.00%
Optimize Financial Inc	--	Mar 31, 26	-25.33K	--
AMALGAMATED BANK	--	Mar 31, 26	-2.17K	--
Parkman Healthcare Partners LLC	--	Mar 31, 26	-124.48K	--
CAXTON CORP	--	Mar 31, 26	-8.92K	--
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	--	Mar 31, 26	-710.63K	--
MEEDER ASSET MANAGEMENT INC	--	Mar 31, 26	-181	--
Point72 Asset Management, L.P.	--	Mar 31, 26	-662.35K	--
Daiwa Securities Group Inc.	--	Mar 31, 26	-258	--
Brevan Howard Capital Management LP	--	Mar 31, 26	-6.20K	--
FMR LLC	11.64M	Dec 31, 25	+2.58M	19.27%
RTW INVESTMENTS, LP	4.17M	Dec 31, 25	+550.00K	6.91%
VANGUARD GROUP INC	4.04M	Dec 31, 25	+984.34K	6.68%
Fairmount Funds Management LLC	4.02M	Dec 31, 25	--	6.65%
VR Adviser, LLC	3.69M	Dec 31, 25	+1.00M	6.10%
PERCEPTIVE ADVISORS LLC	3.07M	Dec 31, 25	+1.84M	5.08%
DRIEHAUS CAPITAL MANAGEMENT LLC	2.88M	Dec 31, 25	+822.04K	4.77%
COMMODORE CAPITAL LP	2.39M	Dec 31, 25	+400.16K	3.95%
TCG Crossover Management, LLC	1.90M	Dec 31, 25	+800.00K	3.15%
TANG CAPITAL MANAGEMENT LLC	1.89M	Dec 31, 25	-1.31M	3.13%
JANUS HENDERSON GROUP PLC	1.83M	Dec 31, 25	+1.82M	3.03%
RA CAPITAL MANAGEMENT, L.P.	1.62M	Dec 31, 25	+1.62M	2.68%
PRICE T ROWE ASSOCIATES INC /MD/	1.60M	Dec 31, 25	+981.26K	2.65%
WELLINGTON MANAGEMENT GROUP LLP	1.55M	Dec 31, 25	-91.03K	2.56%
Paradigm Biocapital Advisors LP	1.47M	Dec 31, 25	--	2.43%
Affinity Asset Advisors, LLC	1.43M	Dec 31, 25	+13.29K	2.37%
BAKER BROS. ADVISORS LP	1.00M	Dec 31, 25	--	1.66%
Polar Capital Holdings Plc	740.33K	Dec 31, 25	-48.46K	1.23%
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	710.63K	Dec 31, 25	+96.96K	1.18%
Point72 Asset Management, L.P.	662.35K	Dec 31, 25	+662.35K	1.10%
NORTHERN TRUST CORP	561.02K	Dec 31, 25	+118.99K	0.93%
BANK OF AMERICA CORP /DE/	419.73K	Dec 31, 25	+74.92K	0.69%
GOLDMAN SACHS GROUP INC	275.06K	Dec 31, 25	-54.47K	0.46%
Woodline Partners LP	265.89K	Dec 31, 25	+134.02K	0.44%
ARMISTICE CAPITAL, LLC	196.43K	Dec 31, 25	+40.43K	0.33%
HighVista Strategies LLC	188.21K	Dec 31, 25	-27.54K	0.31%
MORGAN STANLEY	182.73K	Dec 31, 25	-151.99K	0.30%
BARCLAYS PLC	182.52K	Dec 31, 25	+14.19K	0.30%
Parkman Healthcare Partners LLC	124.48K	Dec 31, 25	-76.27K	0.21%
B Group, Inc.	100.00K	Dec 31, 25	--	0.17%
BALYASNY ASSET MANAGEMENT L.P.	73.47K	Dec 31, 25	+73.47K	0.12%
ALLIANCEBERNSTEIN L.P.	67.50K	Dec 31, 25	+31.27K	0.11%
CITADEL ADVISORS LLC	63.90K	Dec 31, 25	+63.90K	0.11%
SCHRODER INVESTMENT MANAGEMENT GROUP	61.57K	Dec 31, 25	-46.16K	0.10%
Rafferty Asset Management, LLC	53.41K	Dec 31, 25	-6.26K	0.09%
Susquehanna Portfolio Strategies, LLC	53.10K	Dec 31, 25	+31.36K	0.09%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	48.04K	Dec 31, 25	+14.84K	0.08%
AMERIPRISE FINANCIAL INC	38.26K	Dec 31, 25	+38.26K	0.06%
ExodusPoint Capital Management, LP	37.87K	Dec 31, 25	-30.69K	0.06%
Cinctive Capital Management LP	35.94K	Dec 31, 25	+35.94K	0.06%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	35.14K	Dec 31, 25	+8.70K	0.06%
ADAR1 Capital Management, LLC	34.05K	Dec 31, 25	--	0.06%
StemPoint Capital LP	32.38K	Dec 31, 25	+32.38K	0.05%
STATE OF WISCONSIN INVESTMENT BOARD	27.25K	Dec 31, 25	-6.29K	0.05%
VIRGINIA RETIREMENT SYSTEMS ET AL	24.95K	Dec 31, 25	+6.45K	0.04%
Neo Ivy Capital Management	18.26K	Dec 31, 25	+18.26K	0.03%
Global Endowment Management, LP	18.18K	Dec 31, 25	--	0.03%
AQR CAPITAL MANAGEMENT LLC	17.82K	Dec 31, 25	+773	0.03%
Arrowpoint Investment Partners (Singapore) Pte. Ltd.	13.72K	Dec 31, 25	+13.72K	0.02%
Zurcher Kantonalbank (Zurich Cantonalbank)	11.16K	Dec 31, 25	+290	0.02%
CAXTON CORP	8.92K	Dec 31, 25	+8.92K	0.01%
Brevan Howard Capital Management LP	6.20K	Dec 31, 25	+6.20K	0.01%
Quest Partners LLC	3.54K	Dec 31, 25	-62.63K	0.01%
CWM, LLC	1.97K	Dec 31, 25	+10	0.00%
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO	1.59K	Dec 31, 25	--	0.00%
Rockefeller Capital Management L.P.	549	Dec 31, 25	+148	0.00%
Optiver Holding B.V.	240	Dec 31, 25	-260	0.00%
Allworth Financial LP	58	Dec 31, 25	+26	0.00%
Parkside Financial Bank & Trust	35	Dec 31, 25	--	0.00%
US BANCORP \DE\	10	Dec 31, 25	--	0.00%
COMERICA BANK	5	Dec 31, 25	--	0.00%
Opaleye Management Inc.	--	Dec 31, 25	-65.00K	--
Jump Financial, LLC	--	Dec 31, 25	-27.10K	--
DARK FOREST CAPITAL MANAGEMENT LP	--	Dec 31, 25	-14.73K	--
Verition Fund Management LLC	--	Dec 31, 25	-48.50K	--
SRS Capital Advisors, Inc.	--	Dec 31, 25	-121	--
DLD Asset Management, LP	--	Dec 31, 25	-30.00K	--
Quadrature Capital Ltd	--	Dec 31, 25	-19.37K	--
NBW CAPITAL LLC	19.43K	Jun 30, 25	--	0.03%
Lindbrook Capital, LLC	78	Mar 31, 25	+78	0.00%
Nuveen Asset Management, LLC	125.67K	Dec 31, 24	+378	0.21%
Boxer Capital, LLC	696.48K	Sep 30, 24	--	1.15%
Ghost Tree Capital, LLC	60.00K	Sep 30, 24	-190.24K	0.10%
BlackRock Inc.	2.40M	Jun 30, 24	+1.85M	3.98%
CREDIT SUISSE AG/	22.06K	Mar 31, 24	+22.06K	0.04%

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6.91%

Fairmount Funds Management LLC

4.02M

Mar 31, 26

6.65%

PERCEPTIVE ADVISORS LLC

3.78M

Mar 31, 26

+714.00K

6.26%

VR Adviser, LLC

3.69M

Mar 31, 26

6.10%

DRIEHAUS CAPITAL MANAGEMENT LLC

2.79M

Mar 31, 26

-91.64K

4.62%

STATE STREET CORP

2.61M

Mar 31, 26

+344.19K

4.32%

Paradigm Biocapital Advisors LP

1.96M

Mar 31, 26

+490.00K

3.24%

COMMODORE CAPITAL LP

1.91M

Mar 31, 26

-475.87K

3.17%

TCG Crossover Management, LLC

1.90M

Mar 31, 26

3.15%

TANG CAPITAL MANAGEMENT LLC

1.89M

Mar 31, 26

3.13%

WELLINGTON MANAGEMENT GROUP LLP

1.82M

Mar 31, 26

+275.53K

3.02%

Capital International Investors

1.75M

Mar 31, 26

-1.75M

2.89%

GEODE CAPITAL MANAGEMENT, LLC

1.72M

Mar 31, 26

+61.77K

2.85%

JANUS HENDERSON GROUP PLC

1.66M

Mar 31, 26

-172.84K

2.74%

RA CAPITAL MANAGEMENT, L.P.

1.62M

Mar 31, 26

2.68%

PRICE T ROWE ASSOCIATES INC /MD/

1.60M

Mar 31, 26

-3.15K

2.65%

Affinity Asset Advisors, LLC

1.28M

Mar 31, 26

-153.46K

2.12%

BAKER BROS. ADVISORS LP

1.00M

Mar 31, 26

1.66%

JPMORGAN CHASE & CO

979.30K

Mar 31, 26

+916.35K

1.62%

BRAIDWELL LP

932.82K

Mar 31, 26

-701.79K

1.54%

FRANKLIN RESOURCES INC

882.83K

Mar 31, 26

-226.44K

1.46%

Caligan Partners LP

878.13K

Mar 31, 26

+878.13K

1.45%

Siren, L.L.C.

818.60K

Mar 31, 26

1.36%

Polar Capital Holdings Plc

792.85K

Mar 31, 26

+52.52K

1.31%

UBS Group AG

671.24K

Mar 31, 26

-9.33K

1.11%

Capital World Investors

666.56K

Mar 31, 26

+466.39K

1.10%

EMERALD ADVISERS, LLC

613.37K

Mar 31, 26

-22.74K

1.02%

Candriam S.C.A.

610.28K

Mar 31, 26

+184.75K

1.01%

NORTHERN TRUST CORP

578.91K

Mar 31, 26

+17.88K

0.96%

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

562.65K

Mar 31, 26

-11.97K

0.93%

Pictet Asset Management Holding SA

491.65K

Mar 31, 26

-422.31K

0.81%

VANGUARD FIDUCIARY TRUST CO

464.65K

Mar 31, 26

+464.65K

0.77%

EMERALD MUTUAL FUND ADVISERS TRUST

408.11K

Mar 31, 26

-4.26K

0.68%

SAMLYN CAPITAL, LLC

396.66K

Mar 31, 26

+396.66K

0.66%

Blackstone Inc.

292.85K

Mar 31, 26

-208.15K

0.48%

VICTORY CAPITAL MANAGEMENT INC

292.13K

Mar 31, 26

+146.05K

0.48%

GOLDMAN SACHS GROUP INC

269.94K

Mar 31, 26

-5.13K

0.45%

Woodline Partners LP

265.89K

Mar 31, 26

0.44%

MORGAN STANLEY

246.72K

Mar 31, 26

+63.98K

0.41%

UBS ASSET MANAGEMENT AMERICAS INC

207.31K

Mar 31, 26

+145.10K

0.34%

BOOTHBAY FUND MANAGEMENT, LLC

193.03K

Mar 31, 26

+193.03K

0.32%

Bank of New York Mellon Corp

191.40K

Mar 31, 26

-1.44K

0.32%

SILVERARC CAPITAL MANAGEMENT, LLC

186.62K

Mar 31, 26

-1.12K

0.31%

FIRST TRUST ADVISORS LP

178.39K

Mar 31, 26

+178.39K

0.30%

Universal- Beteiligungs- und Servicegesellschaft mbH

170.38K

Mar 31, 26

-830

0.28%

StemPoint Capital LP

167.61K

Mar 31, 26

+135.23K

0.28%

AMERIPRISE FINANCIAL INC

159.22K

Mar 31, 26

+120.96K

0.26%

Nuveen, LLC

153.90K

Mar 31, 26

+2.92K

0.25%

Ensign Peak Advisors, Inc

148.54K

Mar 31, 26

+148.54K

0.25%

MILLENNIUM MANAGEMENT LLC

146.64K

Mar 31, 26

+70.44K

0.24%

HighVista Strategies LLC

146.26K

Mar 31, 26

-41.94K

0.24%

MARSHALL WACE, LLP

139.26K

Mar 31, 26

+139.26K

0.23%

TD ASSET MANAGEMENT INC

137.39K

Mar 31, 26

-12.43K

0.23%

Invesco Ltd.

132.39K

Mar 31, 26

-18.54K

0.22%

DEUTSCHE BANK AG\

129.24K

Mar 31, 26

+7.30K

0.21%

ARMISTICE CAPITAL, LLC

120.93K

Mar 31, 26

-75.50K

0.20%

MANUFACTURERS LIFE INSURANCE COMPANY, THE

112.84K

Mar 31, 26

-16.17K

0.19%

CITADEL ADVISORS LLC

108.14K

Mar 31, 26

+44.23K

0.18%

SEVEN GRAND MANAGERS, LLC

100.00K

Mar 31, 26

0.17%

B Group, Inc.

100.00K

Mar 31, 26

0.17%

F/M Investments LLC

99.46K

Mar 31, 26

-4.26K

0.16%

Swiss National Bank

96.50K

Mar 31, 26

0.16%

ExodusPoint Capital Management, LP

87.06K

Mar 31, 26

+49.19K

0.14%

RHUMBLINE ADVISERS

85.12K

Mar 31, 26

+2.17K

0.14%

MERCER GLOBAL ADVISORS INC /ADV

71.09K

Mar 31, 26

-35.23K

0.12%

ALLIANCEBERNSTEIN L.P.

70.90K

Mar 31, 26

+3.40K

0.12%

Rockefeller Capital Management L.P.

64.00K

Mar 31, 26

+63.45K

0.11%

ALPS ADVISORS INC

63.94K

Mar 31, 26

+231

0.11%

SCHRODER INVESTMENT MANAGEMENT GROUP

63.68K

Mar 31, 26

+2.11K

0.11%

HealthInvest Partners AB

62.73K

Mar 31, 26

+62.73K

0.10%

PRUDENTIAL FINANCIAL INC

59.55K

Mar 31, 26

+59.55K

0.10%

FRED ALGER MANAGEMENT, LLC

59.45K

Mar 31, 26

+59.45K

0.10%

Rafferty Asset Management, LLC

56.92K

Mar 31, 26

+3.51K

0.09%

BALYASNY ASSET MANAGEMENT L.P.

55.48K

Mar 31, 26

-17.99K

0.09%

VOYA INVESTMENT MANAGEMENT LLC

53.97K

Mar 31, 26

+26.69K

0.09%

Susquehanna Portfolio Strategies, LLC

53.10K

Mar 31, 26

0.09%

DIMENSIONAL FUND ADVISORS LP

47.70K

Mar 31, 26

-29.59K

0.08%

BARCLAYS PLC

45.79K

Mar 31, 26

-136.74K

0.08%

Legal & General Group Plc

44.79K

Mar 31, 26

-11.66K

0.07%

MetLife Investment Management, LLC

38.41K

Mar 31, 26

+396

0.06%

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

36.32K

Mar 31, 26

+1.18K

0.06%

VANGUARD ASSET MANAGEMENT, Ltd

33.23K

Mar 31, 26

+33.23K

0.06%

WELLS FARGO & COMPANY/MN

33.21K

Mar 31, 26

-49.21K

0.05%

Vanguard Global Advisers, LLC

31.14K

Mar 31, 26

+31.14K

0.05%

SUSQUEHANNA INTERNATIONAL GROUP, LLP

28.96K

Mar 31, 26

+22.85K

0.05%

Cinctive Capital Management LP

27.43K

Mar 31, 26

-8.51K

0.05%

STATE OF WISCONSIN INVESTMENT BOARD

26.52K

Mar 31, 26

-729

0.04%

PROFUND ADVISORS LLC

26.04K

Mar 31, 26

+5.45K

0.04%

Waverly Advisors, LLC

25.97K

Mar 31, 26

+12

0.04%

TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY

25.80K

Mar 31, 26

0.04%

XTX Topco Ltd

24.43K

Mar 31, 26

+24.43K

0.04%

NEW YORK STATE COMMON RETIREMENT FUND

22.27K

Mar 31, 26

+3.10K

0.04%

Ellsworth Advisors, LLC

21.96K

Mar 31, 26

+21.96K

0.04%

AQR CAPITAL MANAGEMENT LLC

20.87K

Mar 31, 26

+3.05K

0.03%

RAYMOND JAMES FINANCIAL INC

19.75K

Mar 31, 26

+19.75K

0.03%

Assenagon Asset Management S.A.

18.65K

Mar 31, 26

-3.49K

0.03%

BNP PARIBAS ARBITRAGE, SNC

18.63K

Mar 31, 26

+6.79K

0.03%

Police & Firemen's Retirement System of New Jersey

18.36K

Mar 31, 26

0.03%

Global Endowment Management, LP

18.18K

Mar 31, 26

0.03%

KENNEDY CAPITAL MANAGEMENT LLC

16.87K

Mar 31, 26

+16.87K

0.03%

State of New Jersey Common Pension Fund D

16.72K

Mar 31, 26

+22

0.03%

INTECH INVESTMENT MANAGEMENT LLC

16.44K

Mar 31, 26

-1.83K

0.03%

Creative Planning

15.49K

Mar 31, 26

+15.49K

0.03%

Zurcher Kantonalbank (Zurich Cantonalbank)

13.96K

Mar 31, 26

+2.79K

0.02%

China Universal Asset Management Co., Ltd.

13.94K

Mar 31, 26

+1.29K

0.02%

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM

13.90K

Mar 31, 26

+4.88K

0.02%

ProShare Advisors LLC

13.50K

Mar 31, 26

-2.49K

0.02%

Arizona State Retirement System

13.44K

Mar 31, 26

-359

0.02%

SG Americas Securities, LLC

13.40K

Mar 31, 26

-9.95K

0.02%

Vanguard Investments Australia, Ltd.

12.81K

Mar 31, 26

+12.81K

0.02%

BROWN ADVISORY INC

12.40K

Mar 31, 26

+12.40K

0.02%

CITIGROUP INC

12.01K

Mar 31, 26

-88.05K

0.02%

KLP KAPITALFORVALTNING AS

10.90K

Mar 31, 26

+500

0.02%

Russell Investments Group, Ltd.

9.93K

Mar 31, 26

+4.38K

0.02%

Carlyle Group Inc.

9.62K

Mar 31, 26

0.02%

Man Group plc

9.55K

Mar 31, 26

+9.55K

0.02%

MARTINGALE ASSET MANAGEMENT L P

9.08K

Mar 31, 26

+2.15K

0.02%

SEI INVESTMENTS CO

8.97K

Mar 31, 26

+2.86K

0.01%

Tower Research Capital LLC (TRC)

8.79K

Mar 31, 26

+8.37K

0.01%

Bridgefront Capital, LLC

8.65K

Mar 31, 26

+8.65K

0.01%

TUDOR INVESTMENT CORP ET AL

8.36K

Mar 31, 26

-1.76K

0.01%

RWC Asset Management LLP

8.17K

Mar 31, 26

+8.17K

0.01%

Virtus Investment Advisers, Inc.

8.11K

Mar 31, 26

+197

0.01%

Virtu Financial LLC

8.09K

Mar 31, 26

+8.09K

0.01%

CAPSTONE INVESTMENT ADVISORS, LLC

7.54K

Mar 31, 26

+7.54K

0.01%

E Fund Management Co., Ltd.

7.16K

Mar 31, 26

+7.16K

0.01%

Scientech Research LLC

7.09K

Mar 31, 26

+7.09K

0.01%

TWO SIGMA SECURITIES, LLC

6.85K

Mar 31, 26

+6.85K

0.01%

AlphaCentric Advisors LLC

6.63K

Mar 31, 26

+6.63K

0.01%

XPONANCE, INC.

6.45K

Mar 31, 26

+6.45K

0.01%

TEACHER RETIREMENT SYSTEM OF TEXAS

6.28K

Mar 31, 26

-893

0.01%

Arrowpoint Investment Partners (Singapore) Pte. Ltd.

6.14K

Mar 31, 26

-7.58K

0.01%

High Net Worth Advisory Group LLC

6.00K

Mar 31, 26

+6.00K

0.01%

LOS ANGELES CAPITAL MANAGEMENT LLC

5.86K

Mar 31, 26

-7.02K

0.01%

Ameritas Investment Partners, Inc.

5.59K

Mar 31, 26

0.01%

LANDSCAPE CAPITAL MANAGEMENT, L.L.C.

5.20K

Mar 31, 26

+5.20K

0.01%

Persistent Asset Partners Ltd

4.80K

Mar 31, 26

+2.56K

0.01%

DeepCurrents Investment Group LLC

4.74K

Mar 31, 26

+4.74K

0.01%

Quantinno Capital Management LP

4.56K

Mar 31, 26

+4.56K

0.01%

STRS OHIO

4.50K

Mar 31, 26

+4.50K

0.01%

Vanguard Personalized Indexing Management, LLC

4.40K

Mar 31, 26

+4.40K

0.01%

PRINCIPAL FINANCIAL GROUP INC

4.30K

Mar 31, 26

+4.30K

0.01%

Mirae Asset Global Investments Co., Ltd.

4.10K

Mar 31, 26

+327

0.01%

Union Bancaire Privee, UBP SA

3.88K

Mar 31, 26

+3.88K

0.01%

ROYAL BANK OF CANADA

3.25K

Mar 31, 26

+1.26K

0.01%

ABS Direct Equity Fund LLC

2.80K

Mar 31, 26

+2.80K

0.00%

EverSource Wealth Advisors, LLC

2.34K

Mar 31, 26

+2.27K

0.00%

CWM, LLC

2.10K

Mar 31, 26

+135

0.00%

NISA INVESTMENT ADVISORS, LLC

1.92K

Mar 31, 26

+1.21K

0.00%

GF FUND MANAGEMENT CO. LTD.

1.74K

Mar 31, 26

+220

0.00%

PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO

1.59K

Mar 31, 26

0.00%

KBC Group NV

1.37K

Mar 31, 26

+1.37K

0.00%

Sterling Capital Management LLC

1.05K

Mar 31, 26

-559

0.00%

Patient Square Capital LP

1.00K

Mar 31, 26

-149.00K

0.00%

GROUP ONE TRADING, L.P.

901

Mar 31, 26

+501

0.00%

BNP Paribas Asset Management Holding S.A.

888

Mar 31, 26

+232

0.00%

Neo Ivy Capital Management

598

Mar 31, 26

-17.66K

0.00%

Kemnay Advisory Services Inc.

574

Mar 31, 26

+574

0.00%

CLEAR STREET MARKETS LLC

562

Mar 31, 26

+562

0.00%

GAMMA Investing LLC

523

Mar 31, 26

+193

0.00%

ADVISOR GROUP HOLDINGS, INC.

498

Mar 31, 26

+131

0.00%

Optiver Holding B.V.

288

Mar 31, 26

+48

0.00%

Caitong International Asset Management Co., Ltd

286

Mar 31, 26

+286

0.00%

Delos Wealth Advisors, LLC

250

Mar 31, 26

+250

0.00%

Smartleaf Asset Management LLC

157

Mar 31, 26

+157

0.00%

QUADRANT CAPITAL GROUP LLC

146

Mar 31, 26

+146

0.00%

PNC FINANCIAL SERVICES GROUP, INC.

123

Mar 31, 26

+37

0.00%

Allworth Financial LP

117

Mar 31, 26

+59

0.00%

ROTHSCHILD INVESTMENT LLC

Mar 31, 26

+17

0.00%

US BANCORP \DE\

Mar 31, 26

+87

0.00%

Quantbot Technologies LP

Mar 31, 26

+88

0.00%

Farther Finance Advisors, LLC

Mar 31, 26

+37

0.00%

SIGNATUREFD, LLC

Mar 31, 26

0.00%

Larson Financial Group LLC

Mar 31, 26

-108

0.00%

Parkside Financial Bank & Trust

Mar 31, 26

0.00%

Parallel Advisors, LLC

Mar 31, 26

+32

0.00%

IFP Advisors, Inc

Mar 31, 26

0.00%

SRS Capital Advisors, Inc.

Mar 31, 26

+18

0.00%

Bare Financial Services, Inc

Mar 31, 26

+16

0.00%

MAI Capital Management

Mar 31, 26

+13

0.00%

FIFTH THIRD BANCORP

Mar 31, 26

0.00%

SBI Securities Co., Ltd.

Mar 31, 26

0.00%

MASSMUTUAL TRUST CO FSB/ADV

Mar 31, 26

0.00%

TWIN PEAKS WEALTH ADVISORS, LLC

Mar 31, 26

0.00%

Optimize Financial Inc

Mar 31, 26

-25.33K

AMALGAMATED BANK

Mar 31, 26

-2.17K

Parkman Healthcare Partners LLC

Mar 31, 26

-124.48K

CAXTON CORP

Mar 31, 26

-8.92K

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)

Mar 31, 26

-710.63K

MEEDER ASSET MANAGEMENT INC

Mar 31, 26

-181

Point72 Asset Management, L.P.

Mar 31, 26

-662.35K

Daiwa Securities Group Inc.

Mar 31, 26

-258

Brevan Howard Capital Management LP

Mar 31, 26

-6.20K

FMR LLC

11.64M

Dec 31, 25

+2.58M

19.27%

RTW INVESTMENTS, LP

4.17M

Dec 31, 25

+550.00K

6.91%

VANGUARD GROUP INC

4.04M

Dec 31, 25

+984.34K

6.68%

Fairmount Funds Management LLC

4.02M

Dec 31, 25

6.65%

VR Adviser, LLC

3.69M

Dec 31, 25

+1.00M

6.10%

PERCEPTIVE ADVISORS LLC

3.07M

Dec 31, 25

+1.84M

5.08%

DRIEHAUS CAPITAL MANAGEMENT LLC

2.88M

Dec 31, 25

+822.04K

4.77%

COMMODORE CAPITAL LP

2.39M

Dec 31, 25

+400.16K

3.95%

TCG Crossover Management, LLC

1.90M

Dec 31, 25

+800.00K

3.15%

TANG CAPITAL MANAGEMENT LLC

1.89M

Dec 31, 25

-1.31M

3.13%

JANUS HENDERSON GROUP PLC

1.83M

Dec 31, 25

+1.82M

3.03%

RA CAPITAL MANAGEMENT, L.P.

1.62M

Dec 31, 25

+1.62M

2.68%

PRICE T ROWE ASSOCIATES INC /MD/

1.60M

Dec 31, 25

+981.26K

2.65%

WELLINGTON MANAGEMENT GROUP LLP

1.55M

Dec 31, 25

-91.03K

2.56%

Paradigm Biocapital Advisors LP

1.47M

Dec 31, 25

2.43%

Affinity Asset Advisors, LLC

1.43M

Dec 31, 25

+13.29K

2.37%

BAKER BROS. ADVISORS LP

1.00M

Dec 31, 25

1.66%

Polar Capital Holdings Plc

740.33K

Dec 31, 25

-48.46K

1.23%

DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)

710.63K

Dec 31, 25

+96.96K

1.18%

Point72 Asset Management, L.P.

662.35K

Dec 31, 25

+662.35K

1.10%

NORTHERN TRUST CORP

561.02K

Dec 31, 25

+118.99K

0.93%

BANK OF AMERICA CORP /DE/

419.73K

Dec 31, 25

+74.92K

0.69%

GOLDMAN SACHS GROUP INC

275.06K

Dec 31, 25

-54.47K

0.46%

Woodline Partners LP

265.89K

Dec 31, 25

+134.02K

0.44%

ARMISTICE CAPITAL, LLC

196.43K

Dec 31, 25

+40.43K

0.33%

HighVista Strategies LLC

188.21K

Dec 31, 25

-27.54K

0.31%

MORGAN STANLEY

182.73K

Dec 31, 25

-151.99K

0.30%

BARCLAYS PLC

182.52K

Dec 31, 25

+14.19K

0.30%

Parkman Healthcare Partners LLC

124.48K

Dec 31, 25

-76.27K

0.21%

B Group, Inc.

100.00K

Dec 31, 25

0.17%

BALYASNY ASSET MANAGEMENT L.P.

73.47K

Dec 31, 25

+73.47K

0.12%

ALLIANCEBERNSTEIN L.P.

67.50K

Dec 31, 25

+31.27K

0.11%

CITADEL ADVISORS LLC

63.90K

Dec 31, 25

+63.90K

0.11%

SCHRODER INVESTMENT MANAGEMENT GROUP

61.57K

Dec 31, 25

-46.16K

0.10%

Rafferty Asset Management, LLC

53.41K

Dec 31, 25

-6.26K

0.09%

Susquehanna Portfolio Strategies, LLC

53.10K

Dec 31, 25

+31.36K

0.09%

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

48.04K

Dec 31, 25

+14.84K

0.08%

AMERIPRISE FINANCIAL INC

38.26K

Dec 31, 25

+38.26K

0.06%

ExodusPoint Capital Management, LP

37.87K

Dec 31, 25

-30.69K

0.06%

Cinctive Capital Management LP

35.94K

Dec 31, 25

+35.94K

0.06%

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

35.14K

Dec 31, 25

+8.70K

0.06%

ADAR1 Capital Management, LLC

34.05K

Dec 31, 25

0.06%

StemPoint Capital LP

32.38K

Dec 31, 25

+32.38K

0.05%

STATE OF WISCONSIN INVESTMENT BOARD

27.25K

Dec 31, 25

-6.29K

0.05%

VIRGINIA RETIREMENT SYSTEMS ET AL

24.95K

Dec 31, 25

+6.45K

0.04%

Neo Ivy Capital Management

18.26K

Dec 31, 25

+18.26K

0.03%

Global Endowment Management, LP

18.18K

Dec 31, 25

0.03%

AQR CAPITAL MANAGEMENT LLC

17.82K

Dec 31, 25

+773

0.03%

Arrowpoint Investment Partners (Singapore) Pte. Ltd.

13.72K

Dec 31, 25

+13.72K

0.02%

Zurcher Kantonalbank (Zurich Cantonalbank)

11.16K

Dec 31, 25

+290

0.02%

CAXTON CORP

8.92K

Dec 31, 25

+8.92K

0.01%

Brevan Howard Capital Management LP

6.20K

Dec 31, 25

+6.20K

0.01%

Quest Partners LLC

3.54K

Dec 31, 25

-62.63K

0.01%

CWM, LLC

1.97K

Dec 31, 25

+10

0.00%

PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO

1.59K

Dec 31, 25

0.00%

Rockefeller Capital Management L.P.

549

Dec 31, 25

+148

0.00%

Optiver Holding B.V.

240

Dec 31, 25

-260

0.00%

Allworth Financial LP

Dec 31, 25

+26

0.00%

Parkside Financial Bank & Trust

Dec 31, 25

0.00%

US BANCORP \DE\

Dec 31, 25

0.00%

COMERICA BANK

Dec 31, 25

0.00%

Opaleye Management Inc.

Dec 31, 25

-65.00K

Jump Financial, LLC

Dec 31, 25

-27.10K

DARK FOREST CAPITAL MANAGEMENT LP

Dec 31, 25

-14.73K

Verition Fund Management LLC

Dec 31, 25

-48.50K

SRS Capital Advisors, Inc.

Dec 31, 25

-121

DLD Asset Management, LP

Dec 31, 25

-30.00K

Quadrature Capital Ltd

Dec 31, 25

-19.37K

NBW CAPITAL LLC

19.43K

Jun 30, 25

0.03%

Lindbrook Capital, LLC

Mar 31, 25

+78

0.00%

Nuveen Asset Management, LLC

125.67K

Dec 31, 24

+378

0.21%

Boxer Capital, LLC

696.48K

Sep 30, 24

1.15%

Ghost Tree Capital, LLC

60.00K

Sep 30, 24

-190.24K

0.10%

BlackRock Inc.

2.40M

Jun 30, 24

+1.85M

3.98%

CREDIT SUISSE AG/

22.06K

Mar 31, 24

+22.06K

0.04%