Spyre Therapeutics, Inc.SYRENASDAQ
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Price-to-earnings ratio
Latest
-73.04
↓ 625% vs avg
Percentile
P0
Near historical low
Streak
2 yr
Consecutive declineCompressed
Average
-10.07
Historical baseline
| Period | Value | YoY Change |
|---|---|---|
| 2025 | -73.04 | -1287.8% |
| 2024 | -5.26 | -1101.3% |
| 2023 | -0.44 | +3.2% |
| 2022 | -0.45 | +90.5% |
| 2021 | -4.75 | +8.6% |
| 2020 | -5.19 | -66.5% |
| 2019 | -3.12 | +11.3% |
| 2018 | -3.52 | -17.0% |
| 2017 | -3.00 | -53.1% |
| 2016 | -1.96 | - |