ARVN
Earnings in 3 days · May 7, 2026 · Before open
Signal
Mixed11
Price
1
Move+2.85%Positive session
Volume
1
Volume1.3× avgNormal activity
Technical
1
RSIRSI 42Momentum negative
PRICE
Prev Close
10.51
Open
10.02
Day Range9.85 – 10.94
9.85
10.94
52W Range5.90 – 14.51
5.90
14.51
57% of range
VOLUME & SIZE
Avg Volume
855.6K
FUNDAMENTALS
P/E Ratio
-9.5x
Not profitable
EPS (TTM)
Div Yield
No dividend
Beta
1.45
Market-like
Quick Read
TrendInsufficient MA data
Momentum
BULLISH
100% gross margin
Valuation
FAIR
P/E not available
Health
MODERATE
CR 4.9 · FCF negative
Bullish
Key MetricsTTM
Market Cap$692.38M
Revenue TTM$262.60M
Net Income TTM-$80.80M
Free Cash Flow-$275.70M
Gross Margin99.5%
Net Margin-30.8%
Operating Margin-44.0%
Return on Equity-14.3%
Return on Assets-11.3%
Debt / Equity0.02
Current Ratio4.92
EPS TTM$-1.24
Alpha SignalsFull Analysis →
What Moves This Stock

ARV-471 (breast cancer) Phase 3 trial enrollment updates and interim efficacy data - primary near-term catalyst

ARV-110 (prostate cancer) Phase 2 expansion data and potential Phase 3 initiation decisions

New partnership announcements or expansion of existing collaborations (Pfizer, Bayer, Genentech)

FDA regulatory interactions, breakthrough therapy designations, or accelerated approval pathway eligibility

Macro Sensitivity
Economic Cycle

low - Clinical trial timelines and regulatory processes are largely insulated from GDP fluctuations. However, severe recessions can impact: (1) ability to raise capital at attractive valuations, (2) pharmaceutical partner willingness to fund collaborations, and (3) M&A appetite from potential acquirers. Biotech sector historically shows modest correlation to broader economic cycles.

Interest Rates

Rising rates negatively impact valuation through higher discount rates applied to distant future cash flows (product revenues not expected until 2027+). Higher rates also increase cost of capital for future financings and reduce investor appetite for unprofitable growth stocks. With 5.70x current ratio and minimal debt (0.02 D/E), immediate financing cost impact is negligible, but future dilution risk increases in high-rate environments.

Key Risks

Clinical trial failure risk - ARV-471 or ARV-110 missing efficacy/safety endpoints would eliminate 70%+ of company value given pipeline concentration

Regulatory approval uncertainty - FDA may require additional trials or reject applications even with positive Phase 3 data, extending timeline 2-3 years

Competitive protein degradation platforms from Nurix, Kymera, C4 Therapeutics targeting similar mechanisms and indications

Investor Profile

growth - High-risk, high-reward clinical-stage biotech attracts speculative growth investors betting on binary clinical outcomes. Institutional ownership likely concentrated in specialized healthcare funds. Not suitable for value or income investors given negative earnings, no dividends, and distant profitability timeline. Momentum traders active around data readout catalysts.

Watch on Earnings
ARV-471 Phase 3 trial enrollment completion and interim analysis timing announcementsARV-110 objective response rates and duration of response in Phase 2 expansion cohortsCash and marketable securities balance relative to quarterly burn rateNew collaboration deal terms - upfront payments, milestone structures, royalty rates
Health Radar
3 strong3 concern
44/100
Liquidity
4.92Strong
Leverage
0.02Strong
Coverage
0.0xConcern
ROE
-14.3%Concern
ROIC
-20.0%Concern
Cash
$143MStrong
ANALYST COVERAGE26 analysts
BUY
+1.8%upside to target
L $10.00
Med $11.00consensus
H $18.00
Buy
2077%
Hold
519%
Sell
14%
20 Buy (77%)5 Hold (19%)1 Sell (4%)
Full report →
Stock Health
Composite Score
3 of 5 signals bullish
7/10
Technicals
RSI RangeRSI 42 — Bearish momentum
Volume
Volume FlowAccumulation — institutional buying
Fundamentals
Last EarningsMissed estimates
Analyst ConsensusBuy
LiquidityCurrent Ratio 4.92 — healthy liquidity
Upcoming Events
EEarnings ReportMay 5, 2026
Tomorrow
DEx-Dividend DateAug 2, 2026
In 90 days
Technicals
Technical SetupMIXED
Technicals →

Trend

PullbackGolden Cross · 50D leads 200D by 39.8%

-3.2% vs SMA 50 · +35.3% vs SMA 200

Momentum

RSI41.6
Momentum fading
MACD+0.19
Above zero — bullish momentum · compressing
Market Position
Price Levels
52W High
$14.51+34.2%
EMA 50
$11.24+4.0%
Current
$10.81
EMA 200
$7.99-26.1%
52W Low
$5.90-45.4%
52-Week RangeMid-range
$5.9057th %ile$14.51
Squeeze SetupVolume-based
Moderate Squeeze Setup

Accumulation pattern present — more buying days than selling over the past 20 sessions. Volume conditions support gradual price improvement.

20-Day Money Flow
Acc days:3
Dist days:1
Edge:+2 acc
Volume Context
Avg Vol (50D)2.0M
Recent Vol (5D)
2.0M+0%

Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.

Earnings & Analysts

ANALYST ESTIMATES

Consensus of 13 analysts
Analyst revisions:EPS↑ Revised UpRevenue↑ Revised Up

Analyst consensus estimates · Actuals replace estimates as reported

YearRevenue Est.Rev GthEPS Est.EPS GthRangeAnalysts
FY2025
$289.4M
$276.2M$317.2M
-$0.71
±50%
High13
FY2026(current)
$93.2M
$66.8M$143.5M
-67.8%-$3.32
±23%
High13
FY2027
$83.2M
$31.7M$144.3M
-10.7%-$3.55
±22%
High11
Range confidence:Tight (high)ModerateWide (low)
Earnings HistoryARVN
Last 8Q
+37.8%avg beat
Beat 7 of 8 quartersMissed 1 Estimates rising
+34%
Q2'24
+32%
Q3'24
+23%
Q4'24
+41%
Q1'25
+233%
Q2'25
+3%
Q3'25
+36%
Q4'25
-100%
Q1'26
Beat
Miss
Estimate
Deeper color = bigger beat/miss
* Negative EPS shown at reduced height
Analyst Activity
All ratings →
No recent activity
CitigroupNeutral → Buy
Jan 6
UPGRADE
Goldman SachsSell
Oct 15
DOWNGRADE
WedbushBuy → Neutral
Mar 12
DOWNGRADE
OppenheimerOutperform → Perform
Mar 11
DOWNGRADE
Wells FargoEqual-Weight → Overweight
Dec 19
UPGRADE
JefferiesBuy
Dec 6
UPGRADE
GuggenheimNeutral → Buy
Nov 20
UPGRADE
WedbushOutperform
Oct 23
UPGRADE
GuggenheimNeutral
Jan 12
DOWNGRADE
Wells FargoEqual-Weight
Jan 3
DOWNGRADE
Zacks Investment Re…Hold
Apr 26
DOWNGRADE
Insider Activity
SEC Filings →
1 Buy/5 SellsNet Selling
Berkowitz NoahChief Medical …
$71K
Mar 18
SELL
Morrison BriggsDir
$268K
Mar 6
BUY
Houston John GDir
$62K
Feb 27
SELL
Houston John GDir
$249K
Feb 27
SELL
Houston John GDir
$155K
Feb 27
SELL
Loomis David KChief Accounti…
$13K
Feb 23
SELL
Financials

INSTITUTIONAL OWNERSHIP

1
Nuveen, LLC
406K
2
WASATCH ADVISORS LP
282K
3
Y-Intercept (Hong Kong) Ltd
173K
4
HSBC HOLDINGS PLC
89K
5
SG Americas Securities, LLC
86K
6
TEMA ETFS LLC
84K
7
Yelin Lapidot Holdings Management Ltd.
47K
8
STRS OHIO
40K
News & Activity

ARVN News

20 articles · 4h ago

About

Arvinas is a clinical-stage biopharmaceutical company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC® targeted protein degraders, that are designed to harness the body's own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins. In addition to its robust preclinical pipeline of PROTAC® protein degraders against validated and "undruggable" targets, the company has two clinical-stage programs: ARV-110 for the treatment of men with metastatic castrate-resistant prostate cancer; and ARV-471 for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer.

Industry
Medicinal and Botanical Manufacturing
Randy TeelCEO, President & Director
Kelly PageSenior Vice President & Global Head of Oncology Strategy and Program Leadership
Paul McInultySenior Vice President of Regulatory Affairs
PeersHealth Care(7 companies)
Screen sector →
SymbolPriceDay %Mkt CapP/ERev GrwMarginELO
ARVN
$10.81+0.00%$672M1500
$69.60-3.59%$13.3B+12626.1%-14525.8%1500
$521.85-0.71%$11.8B+43205.3%-3008.0%1500
$91.53+0.60%$11.5B+3288.2%-4239.0%1500
$182.91-1.59%$10.7B29.2+1871.5%680.1%1500
$228.44-0.59%$10.6B+6554.5%-2868.8%1500
$76.42+1.81%$10.5B51.8+2325815.3%-19.7%1500
Sector avg-0.58%40.5+398893.5%-3996.9%1500