GYRE
Next earnings: Aug 10, 2026 · Before open
Signal
Bearish Setup2
Price
1
Move-6.43%Selling pressure
Volume
1
Volume1.0× avgNormal activity
Technical
1
RSIRSI 32Momentum negative
PRICE
Prev Close
7.00
Open
6.87
Day Range6.55 – 6.92
6.55
6.92
52W Range6.55 – 11.61
6.55
11.61
0% of range
VOLUME & SIZE
Avg Volume
99.0K
FUNDAMENTALS
P/E Ratio
-81.9x
Not profitable
EPS (TTM)
Div Yield
No dividend
Performance
1D
-6.43%
5D
-9.15%
1M
-18.33%
3M
-18.33%
6M
-18.02%
YTD
-7.22%
1Y
-40.13%
Worst: 1Y (-40.13%)
Quick Read
TrendInsufficient MA data
Momentum
BULLISH
revenue +16% YoY · 95% gross margin
Valuation
FAIR
P/E not available
Health
STRONG
CR 4.6 · FCF $0.03/sh
Strong Buy
Key MetricsTTM
Market Cap$635.31M
Revenue TTM$117.05M
Net Income TTM-$6.29M
Free Cash Flow$3.04M
Gross Margin95.1%
Net Margin-5.4%
Operating Margin-0.1%
Return on Equity-6.3%
Return on Assets-3.9%
Debt / Equity0.01
Current Ratio4.64
EPS TTM$-0.07
Alpha SignalsFull Analysis →
What Moves This Stock

Clinical trial data readouts and FDA regulatory milestones for pipeline candidates

Quarterly prescription volume trends and market share dynamics for commercialized products

Partnership announcements, licensing deals, or M&A speculation given $700M market cap

Reimbursement decisions from Medicare/Medicaid and private payers affecting product access

Macro Sensitivity
Economic Cycle

low - Pharmaceutical demand is largely non-discretionary and driven by disease prevalence rather than economic conditions. However, elective procedures or non-critical therapies may see modest utilization pressure during recessions. The 6.19x current ratio provides substantial liquidity buffer against economic volatility. Biotech valuations are more sensitive to risk appetite and growth stock multiples than underlying business fundamentals.

Interest Rates

Rising interest rates negatively impact biotech valuations through higher discount rates applied to future cash flows, particularly for pre-profitable or early-commercial companies. The 46.7x EV/EBITDA multiple makes GYRE vulnerable to multiple compression as 10-year Treasury yields rise. However, minimal debt (0.01 D/E) eliminates refinancing risk. Higher rates also reduce speculative capital flows into high-risk biotech sectors, pressuring stock performance independent of operational results.

Key Risks

Regulatory pathway changes or heightened FDA scrutiny increasing approval timelines and development costs

Medicare drug price negotiation expansion under IRA legislation potentially compressing realized pricing for commercialized products

Patent cliff exposure if key product exclusivity expires without pipeline replacement, given concentrated revenue base

Investor Profile

growth - The premium valuation multiples (6.9x P/S, 46.7x EV/EBITDA), recent profitability inflection (113% net income growth), and biotech sector positioning attract growth-oriented investors seeking pipeline optionality and commercial expansion. The -35.8% one-year return suggests prior momentum investors have exited, leaving value-oriented biotech specialists and long-term holders. Minimal dividend yield (implied by cash flow profile) eliminates income investor appeal.

Watch on Earnings
Quarterly product revenue trends and prescription volume data from third-party sources (IQVIA, Symphony Health)R&D pipeline progression through Phase I/II/III milestones and regulatory submission timelinesCash burn rate and quarters of runway based on operating cash flow trendsGross-to-net revenue deductions indicating payer rebate and discount pressure
Health Radar
3 strong3 concern
46/100
Liquidity
4.64Strong
Leverage
0.01Strong
Coverage
0.0xConcern
ROE
-6.3%Concern
ROIC
0.4%Concern
Cash
$37MStrong
Analyst Coverage

No analyst coverage available for this stock.

Stock Health
Composite Score
2 of 4 signals bullish
4/10
Technicals
RSI RangeRSI 32 — Bearish momentum
Volume
Volume FlowDistribution — institutional selling
Fundamentals
Last EarningsBeat estimates
LiquidityCurrent Ratio 4.64 — healthy liquidity

1 signal unavailable — limited data for this stock

Upcoming Events
EEarnings ReportMay 17, 2026
Tomorrow
DEx-Dividend DateAug 14, 2026
In 90 days
PDividend PaymentAug 31, 2026
In 107 days
Technicals
Technical SetupBULLISH
Technicals →

Trend

UptrendGolden Cross · 50D leads 200D by 300.0%

+454.6% vs SMA 50 · +2118.5% vs SMA 200

Momentum

RSI31.9
Momentum fading
MACD+2.62
Above zero — bullish momentum · expanding
Market Position
Price Levels
52W High
$11.61+77.3%
Current
$6.55
52W Low
$6.55+0.0%
EMA 50
$1.41-78.5%
EMA 200
$0.3620-94.5%
52-Week RangeNear 52-week low
$6.550th %ile$11.61
Squeeze SetupVolume-based
Distribution Pressure

Distribution pattern detected. More selling days than accumulation over the past 20 sessions. Not a conducive environment for a squeeze.

20-Day Money Flow
Acc days:1
Dist days:2
Edge:+1 dist
Volume Context
Avg Vol (50D)96K
Recent Vol (5D)
91K-5%

Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.

Earnings & Analysts

ANALYST ESTIMATES

Consensus of 2 analysts
Analyst revisions:EPS↑ Revised UpRevenue↑ Revised Up

Analyst consensus estimates · Actuals replace estimates as reported

YearRevenue Est.Rev GthEPS Est.EPS GthRangeAnalysts
FY2025
$114.8M
$114.0M$115.6M
$0.16
±10%
Low2
FY2026(current)
$102.3M
$100.7M$103.9M
-10.9%-$0.29
±9%
Low2
FY2027
$130.8M
$121.6M$140.0M
+27.8%-$0.10
±9%
Low1
Range confidence:Tight (high)ModerateWide (low)
Earnings HistoryGYRE
Last 8Q
-19.3%avg beat
Beat 2 of 8 quartersMissed 5 Estimates rising
-40%
Q4'23
-14%
Q1'24
-75%
Q1'25
Q2'25
-33%
Q3'25
+20%
Q4'25
-29%
Q1'26
+17%
Q2'26
Beat
Miss
Estimate
Deeper color = bigger beat/miss
* Negative EPS shown at reduced height
Insider Activity
SEC Filings →
0 Buys/6 SellsNet Selling
NET SELLERS$0 bought · $83K sold · 30d window
Luo YingCEO
$1K
May 5
SELL
Luo YingCEO
$81K
May 6
SELL
Ma SongjiangDir
$21K
May 27
SELL
Ma SongjiangDir
$6K
May 28
SELL
Ma SongjiangDir
$22K
May 22
SELL
Ma SongjiangDir
$2K
May 23
SELL
Financials

INSTITUTIONAL OWNERSHIP

1
BlackRock, Inc.
759K
2
GEODE CAPITAL MANAGEMENT, LLC
431K
3
STATE STREET CORP
216K
4
SBI Securities Co., Ltd.
171K
5
CHARLES SCHWAB INVESTMENT MANAGEMENT INC
165K
6
VANGUARD FIDUCIARY TRUST CO
138K
7
NORTHERN TRUST CORP
134K
8
GOLDMAN SACHS GROUP INC
73K
News & Activity

GYRE News

20 articles · 4h ago

About

catalyst is focused on developing novel medicines to address serious medical conditions for patients who need new or better treatment options. we used a scientific approach focused on protease-based therapeutic candidates to build a clinical-stage biopharmaceutical company whose current mission is to develop valuable therapies for patients with hemophilia. learn more about our hemophilia program. a protease is an enzyme that cleaves target proteins. learn more about proteases.

Industry
Research and Development in Biotechnology (except Nanobiotechnology)
CEO
Nassim Usman
Han YingSenior Vice President of Science
Songjiang MaPresident & Director
PeersHealth Care(7 companies)
Screen sector →
SymbolPriceDay %Mkt CapP/ERev GrwMarginELO
GYRE
$6.55-6.43%$635M+1024.1%431.2%1500
$66.13-5.07%$13.0B+12626.1%-14525.8%1500
$94.92-3.79%$12.6B+3288.2%-4239.0%1500
$523.69-3.00%$12.1B+43205.3%-3008.0%1500
$227.72-1.30%$11.7B+6554.5%-2868.8%1500
$57.90-0.86%$11.2B50.3+1459.3%147.7%1500
$76.67-3.79%$10.8B+2325815.3%-19.7%1500
Sector avg-3.46%50.3+341996.1%-3440.3%1500