OPK
Next earnings: Jul 30, 2026 · After close
Signal
Bullish Setup2
Price
1
Move+1.80%Positive session
Volume
1
Volume0.6× avgNormal activity
Technical
1
RSIRSI 55Momentum positive
PRICE
Prev Close
1.11
Open
1.11
Day Range1.11 – 1.13
1.11
1.13
52W Range0.98 – 1.60
0.98
1.60
24% of range
VOLUME & SIZE
Avg Volume
2.7M
FUNDAMENTALS
P/E Ratio
-4.2x
Not profitable
EPS (TTM)
Div Yield
No dividend
Beta
1.54
High vol
Performance
1D
+1.80%
5D
+2.73%
1M
-4.24%
3M
-8.13%
6M
-15.67%
YTD
-10.32%
1Y
-16.91%
Best: 5D (+2.73%)Worst: 1Y (-16.91%)
Quick Read
TrendInsufficient MA data
Momentum
BEARISH
revenue -16% YoY
Valuation
FAIR
P/E not available
Health
MODERATE
CR 3.6 · FCF negative
Neutral
Key MetricsTTM
Market Cap$853.25M
Revenue TTM$581.12M
Net Income TTM-$212.91M
Free Cash Flow-$174.22M
Gross Margin22.7%
Net Margin-36.6%
Operating Margin-34.9%
Return on Equity-16.8%
Return on Assets-11.5%
Debt / Equity0.33
Current Ratio3.61
EPS TTM$-0.28
Alpha SignalsFull Analysis →
What Moves This Stock

BioReference diagnostic testing volumes and reimbursement rate changes from Medicare/Medicaid

Somatrogon commercial uptake and geographic expansion milestones (approved in US, EU, Japan)

Rayaldee prescription trends and formulary access with major pharmacy benefit managers

Clinical trial readouts for pipeline assets and regulatory approval timelines

Macro Sensitivity
Economic Cycle

moderate - Diagnostic testing volumes correlate with healthcare utilization patterns, which decline during recessions as patients defer routine care. However, Medicare/Medicaid reimbursement provides some stability. Pharmaceutical sales are less cyclical but face pricing pressure in weak economic environments.

Interest Rates

Rising rates increase financing costs for the company's debt ($100M+ in borrowings) and make equity dilution more expensive for funding operations. Higher rates also compress valuation multiples for unprofitable growth companies. The company's negative cash flow makes it vulnerable to tighter credit conditions.

Key Risks

Secular decline in diagnostic testing reimbursement rates from CMS and commercial payers, with annual Medicare Clinical Lab Fee Schedule cuts

Competitive pressure from larger diagnostic players (Quest, LabCorp) with superior scale and negotiating leverage

Regulatory risk from FDA approval processes for pharmaceutical pipeline and potential label restrictions

Investor Profile

speculative growth - Attracts biotech/pharma investors betting on pipeline commercialization and turnaround in diagnostic operations. High risk/reward profile given negative cash flow and binary clinical/regulatory outcomes. Not suitable for value or income investors given losses and no dividend.

Watch on Earnings
BioReference quarterly test volumes and revenue per requisition trendsSomatrogon royalty revenue from Pfizer partnership and geographic launch progressOperating cash flow and cash balance relative to quarterly burn rateMedicare reimbursement rate changes from annual Clinical Lab Fee Schedule updates
Health Radar
3 strong3 concern
42/100
Liquidity
3.61Strong
Leverage
0.33Strong
Coverage
-2.0xConcern
ROE
-16.8%Concern
ROIC
-10.9%Concern
Cash
$369MStrong
ANALYST COVERAGE12 analysts
BUY
+165.5%upside to target
L $1.60
Med $3.00consensus
H $4.00
Buy
867%
Hold
325%
Sell
18%
8 Buy (67%)3 Hold (25%)1 Sell (8%)
Full report →
Stock Health
Composite Score
4 of 5 signals bullish
8/10
Technicals
RSI RangeRSI 55 — Bullish momentum
Volume
Volume FlowLean Accumulation
Fundamentals
Last EarningsMissed estimates
Analyst ConsensusBuy
LiquidityCurrent Ratio 3.61 — healthy liquidity
Upcoming Events
EEarnings ReportMay 7, 2026
Tomorrow
DEx-Dividend DateAug 4, 2026
In 90 days
PDividend PaymentSep 1, 2026
In 118 days
Technicals
Technical SetupBEARISH
Technicals →

Trend

DowntrendDeath Cross · 50D trails 200D by 10.5%

-4.5% vs SMA 50 · -14.5% vs SMA 200

Momentum

RSI55.4
Positive momentum, not extended
MACD-0.02
Below zero — bearish pulse · compressing
Market Position
Price Levels
52W High
$1.60+41.6%
EMA 200
$1.37+21.2%
EMA 50
$1.33+17.5%
Current
$1.13
52W Low
$0.9800-13.3%
52-Week RangeNear 52-week low
$0.980024th %ile$1.60
Squeeze SetupVolume-based
Moderate Squeeze Setup

Accumulation pattern present — more buying days than selling over the past 20 sessions. Volume conditions support gradual price improvement.

20-Day Money Flow
Acc days:4
Dist days:1
Edge:+3 acc
Volume Context
Avg Vol (50D)3.1M
Recent Vol (5D)
3.2M+5%

Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.

Earnings & Analysts

ANALYST ESTIMATES

Consensus of 6 analysts
Analyst revisions:EPS↓ Revised DownRevenue↑ Revised Up

Analyst consensus estimates · Actuals replace estimates as reported

YearRevenue Est.Rev GthEPS Est.EPS GthRangeAnalysts
FY2025
$598.1M
$596.7M$599.5M
-$0.35
±19%
High6
FY2026(current)
$537.8M
$528.3M$547.8M
-10.1%-$0.31
±9%
High6
FY2027
$567.7M
$555.8M$581.8M
+5.6%-$0.26
±19%
High6
Range confidence:Tight (high)ModerateWide (low)
Earnings HistoryOPK
Last 8Q
+62.4%avg beat
Beat 5 of 8 quartersMissed 2 Estimates rising
+89%
Q3'24
+130%
Q4'24
+113%
Q1'25
-67%
Q2'25
-58%
Q3'25
+250%
Q4'25
+43%
Q1'26
Q2'26
Beat
Miss
Estimate
Deeper color = bigger beat/miss
* Negative EPS shown at reduced height
Analyst Activity
All ratings →
No recent activity
JefferiesHold
Oct 30
DOWNGRADE
SusquehannaPositive
Jun 29
UPGRADE
Piper SandlerOverweight → Neutral
Jun 29
UPGRADE
UBSNeutral
Jun 29
DOWNGRADE
CitigroupNeutral
Jun 29
DOWNGRADE
Zacks Investment Re…Hold
Apr 26
DOWNGRADE
Insider Activity
SEC Filings →
6 Buys/0 SellsNet Buying
Paganelli John ADir
$11K
Mar 20
BUY
Frost Phillip Md Et…Dir
$257K
Nov 21
BUY
Frost Phillip Md Et…Dir
$255K
Nov 21
BUY
Frost Phillip Md Et…Dir
$118K
Nov 21
BUY
Frost Phillip Md Et…Dir
$5K
Nov 21
BUY
Frost Phillip Md Et…Dir
$133K
Nov 21
BUY
Financials

INSTITUTIONAL OWNERSHIP

1
WASHINGTON GROWTH STRATEGIES LLC
1.4M
2
Y.D. More Investments Ltd
1.3M
3
PFG Investments, LLC
1.1M
4
Nuveen, LLC
847K
5
Assenagon Asset Management S.A.
652K
6
COMMONWEALTH EQUITY SERVICES, LLC
431K
7
HSBC HOLDINGS PLC
238K
8
ProShare Advisors LLC
141K
News & Activity

OPK News

20 articles · 4h ago

About

opko health is a diversified healthcare company that seeks to establish industry leading positions in large, rapidly growing markets. our diagnostics business includes bioreference laboratories, the nation's third largest clinical laboratory with a core genetic testing business and a 400 person sales and marketing team to drive growth and leverage new products, including the 4kscore® prostate cancer test and the claros® 1 in office immunoassay platform. our pharmaceutical business features rayaldee, an fda approved treatment for shpt in stage 3-­4 ckd patients with vitamin d insufficiency (launched in november 2016), varubitm for chemotherapy induced nausea and vomiting (oral formulation launched by partner tesaro and iv formulation pending fda approval), opk88004, a once or twice weekly oxyntomodulin for type 2 diabetes and obesity, in phase 2 clinical trials, among the new class of glp-­1 glucagon receptor dual agonists, and opk88003, a selective androgen receptor modulator for benig

CEO
Phillip Frost
Akhtar AshfaqSenior Vice President of Clinical Research & Development and Medical Affairs - Opko Renal
Steven D. RubinExecutive Vice President of Administration & Director
Hans BernerPresident of OPKO Health Iberoamerica
PeersHealth Care(7 companies)
Screen sector →
SymbolPriceDay %Mkt CapP/ERev GrwMarginELO
OPK
$1.13+1.80%$853M-1490.1%-3718.7%1500
$68.78-0.30%$13.3B+12626.1%-14525.8%1500
$89.52-1.81%$11.7B+3288.2%-4239.0%1500
$502.47-3.12%$11.5B+43205.3%-3008.0%1500
$223.06-0.29%$11.4B+6554.5%-2868.8%1500
$74.93-1.91%$10.5B51.9+2325815.3%-19.7%1500
$175.95-3.34%$10.3B28.0+1871.5%680.1%1500
Sector avg-1.28%39.9+341695.8%-3957.1%1500