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Today's biggest gainers and losers
| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| ARCH Venture Management, LLC | 6.29M | Jun 30, 26 | +6.29M | 11.76% |
| GENERAL ATLANTIC, L.P. | 6.10M | Jun 30, 26 | +6.10M | 11.40% |
| Sofinnova Investments, Inc. | 3.56M | Jun 30, 26 | +3.56M | 6.66% |
| GOLDMAN SACHS GROUP INC | 2.18M | Jun 30, 26 | +2.18M | 4.07% |
| TRV GP VI, LLC | 2.06M | Jun 30, 26 | +2.06M | 3.85% |
| CANADA PENSION PLAN INVESTMENT BOARD | 1.98M | Jun 30, 26 | +1.98M | 3.69% |
| JPMORGAN CHASE & CO | 1.82M | Jun 30, 26 | +1.82M | 3.39% |
| Foresite Capital Management VI LLC | 1.78M | Jun 30, 26 | +1.78M | 3.32% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.31M | Jun 30, 26 | +1.31M | 2.44% |
| FMR LLC | 1.19M | Jun 30, 26 | +1.19M | 2.21% |
| Bellevue Group AG | 1.10M | Jun 30, 26 | +1.10M | 2.05% |
| Siren, L.L.C. | 1.10M | Jun 30, 26 | +1.10M | 2.05% |
| JENNISON ASSOCIATES LLC | 1.08M | Jun 30, 26 | +1.08M | 2.02% |
| RA CAPITAL MANAGEMENT, L.P. | 700.00K | Jun 30, 26 | +700.00K | 1.31% |
| VANGUARD CAPITAL MANAGEMENT LLC | 599.22K | Jun 30, 26 | +599.22K | 1.12% |
| Woodline Partners LP | 586.35K | Jun 30, 26 | +586.35K | 1.10% |
| PERCEPTIVE ADVISORS LLC | 500.00K | Jun 30, 26 | +500.00K | 0.93% |
| BRAIDWELL LP | 500.00K | Jun 30, 26 | +500.00K | 0.93% |
| PRINCIPAL FINANCIAL GROUP INC | 414.67K | Jun 30, 26 | +414.67K | 0.77% |
| abrdn plc | 310.36K | Jun 30, 26 | +310.36K | 0.58% |
| UBS Group AG | 279.18K | Jun 30, 26 | +279.18K | 0.52% |
| BlackRock, Inc. | 229.86K | Jun 30, 26 | +229.86K | 0.43% |
| SEVEN GRAND MANAGERS, LLC | 225.00K | Jun 30, 26 | +225.00K | 0.42% |
| CITADEL ADVISORS LLC | 191.14K | Jun 30, 26 | +191.14K | 0.36% |
| GEODE CAPITAL MANAGEMENT, LLC | 175.87K | Jun 30, 26 | +175.87K | 0.33% |
| Pier Capital, LLC | 169.99K | Jun 30, 26 | +169.99K | 0.32% |
| AMERIPRISE FINANCIAL INC | 131.79K | Jun 30, 26 | +131.79K | 0.25% |
| Sixth Street Partners Management Company, L.P. | 97.69K | Jun 30, 26 | +97.69K | 0.18% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 97.69K | Jun 30, 26 | +97.69K | 0.18% |
| VANGUARD FIDUCIARY TRUST CO | 87.77K | Jun 30, 26 | +87.77K | 0.16% |
| Pentwater Capital Management LP | 83.00K | Jun 30, 26 | +83.00K | 0.16% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 82.56K | Jun 30, 26 | +82.56K | 0.15% |
| Alyeska Investment Group, L.P. | 75.00K | Jun 30, 26 | +75.00K | 0.14% |
| STATE STREET CORP | 66.65K | Jun 30, 26 | +66.65K | 0.12% |
| ALPS ADVISORS INC | 54.33K | Jun 30, 26 | +54.33K | 0.10% |
| TD ASSET MANAGEMENT INC | 47.94K | Jun 30, 26 | +47.94K | 0.09% |
| MILLENNIUM MANAGEMENT LLC | 45.34K | Jun 30, 26 | +45.34K | 0.08% |
| GSA CAPITAL PARTNERS LLP | 33.18K | Jun 30, 26 | +33.18K | 0.06% |
| DAFNA Capital Management LLC | 32.40K | Jun 30, 26 | +32.40K | 0.06% |
| NORTHERN TRUST CORP | 31.80K | Jun 30, 26 | +31.80K | 0.06% |
| ADAR1 Capital Management, LLC | 26.00K | Jun 30, 26 | +26.00K | 0.05% |
| Ghisallo Capital Management LLC | 25.00K | Jun 30, 26 | +25.00K | 0.05% |
| Burkehill Global Management, LP | 25.00K | Jun 30, 26 | +25.00K | 0.05% |
| Squarepoint Ops LLC | 24.75K | Jun 30, 26 | +24.75K | 0.05% |
| HighTower Advisors, LLC | 16.67K | Jun 30, 26 | +16.67K | 0.03% |
| MORGAN STANLEY | 11.69K | Jun 30, 26 | +11.69K | 0.02% |
| XTX Topco Ltd | 10.98K | Jun 30, 26 | +10.98K | 0.02% |
| Zimmer Partners, LP | 10.00K | Jun 30, 26 | +10.00K | 0.02% |
| Weiss Asset Management LP | 10.00K | Jun 30, 26 | +10.00K | 0.02% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 9.08K | Jun 30, 26 | +9.08K | 0.02% |
| Vanguard Global Advisers, LLC | 7.16K | Jun 30, 26 | +7.16K | 0.01% |
| CITIGROUP INC | 2.45K | Jun 30, 26 | +2.45K | 0.00% |
| JONES FINANCIAL COMPANIES LLLP | 2.26K | Jun 30, 26 | +2.26K | 0.00% |
| ASSETMARK, INC | 1.43K | Jun 30, 26 | +1.43K | 0.00% |
| BARCLAYS PLC | 837 | Jun 30, 26 | +837 | 0.00% |
| Integrated Wealth Concepts LLC | 32 | Jun 30, 26 | +32 | 0.00% |
