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Spyre Therapeutics, Inc.
SYRE
NASDAQ
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As of
2025
• vs 2024
Annual
Quarterly
Core Metrics
Market Cap
$11.34B
+935.5%
P/E Ratio
-73.04
-1287.8%
P/S Ratio
0.00
ROE
-21.70%
+46.0%
ROIC
-29.14%
+22.5%
FCF Yield
-1.49%
+89.6%
Debt/Equity
0.00
Current Ratio
13.25
+17.8%
Interest Coverage
0.00x
Per Share
Revenue/Share
$0.00
Net Income/Share
$-0.45
+89.9%
Operating CF/Share
$-0.49
+85.4%
Free CF/Share
$-0.49
+85.4%
Cash/Share
$2.19
-83.0%
Book Value/Share
$2.07
-81.2%
Tangible Book/Share
$2.07
-81.2%
Equity/Share
$2.07
-81.2%
Interest Debt/Share
$0.00
Valuation
Market Cap
$11.34B
+935.5%
Enterprise Value
$11.25B
+1019.1%
P/E Ratio
-73.04
-1287.8%
P/S Ratio
0.00
P/OCF Ratio
-66.98
-863.0%
P/FCF Ratio
-66.98
-863.0%
P/B Ratio
15.85
+649.6%
P/TB Ratio
15.85
+649.6%
EV/Sales
0.00
EV/EBITDA
-53.69
-1010.5%
Profitability
Earnings Yield
-1.37%
+92.8%
FCF Yield
-1.49%
+89.6%
ROE
-21.70%
+46.0%
ROIC
-29.14%
+22.5%
Return on Tangible Assets
-19.95%
+41.6%
Capital Allocation
CapEx/OCF
0.00%
CapEx/Revenue
0.00%
CapEx/Depreciation
0.00
SBC/Revenue
0.00%
Balance Sheet
Debt/Equity
0.00
Debt/Assets
0.00
Net Debt/EBITDA
0.41
-4.9%
Current Ratio
13.25
+17.8%
Interest Coverage
0.00x
Income Quality
1.09
+44.1%
Efficiency
Days Sales Outstanding
0 days
Days Payables Outstanding
19 days
Days Inventory
0 days
Receivables Turnover
0.00x
Payables Turnover
19.28x
Inventory Turnover
0.00x
Special Valuations
Graham Number
--
Graham Net-Net
$2.01
-81.6%