TRDA
Next earnings: Aug 5, 2026 · Before open
Signal
Bearish Setup2
Price
1
Move-6.59%Selling pressure
Volume
1
Volume1.0× avgNormal activity
Technical
1
RSIRSI 33Momentum negative
PRICE
Prev Close
6.83
Open
6.66
Day Range6.31 – 6.76
6.31
6.76
52W Range4.93 – 16.45
4.93
16.45
13% of range
VOLUME & SIZE
Avg Volume
335.0K
FUNDAMENTALS
P/E Ratio
-1.6x
Not profitable
EPS (TTM)
Div Yield
No dividend
Beta
0.94
Market-like
Performance
1D
-6.59%
5D
-3.77%
1M
-54.40%
3M
-41.36%
6M
-27.09%
YTD
-37.94%
1Y
-21.43%
Worst: 1M (-54.40%)
Quick Read
TrendInsufficient MA data
Momentum
BEARISH
revenue -97% YoY · thin -598% gross margin
Valuation
FAIR
P/E not available
Health
MODERATE
CR 13.9 · FCF negative
Lean Bearish
Key MetricsTTM
Market Cap$247.68M
Revenue TTM$5.74M
Net Income TTM-$166.12M
Free Cash Flow-$131.64M
Gross Margin-598.0%
Net Margin-2895.1%
Operating Margin-3109.3%
Return on Equity-51.2%
Return on Assets-49.5%
Debt / Equity0.18
Current Ratio13.90
EPS TTM$-3.97
Alpha SignalsFull Analysis →
What Moves This Stock

ENTR-601-44 Phase 2 clinical trial data readouts for myotonic dystrophy type 1 (primary endpoint: splicing correction, functional outcomes)

DMD program advancement and preclinical/clinical data for exon-skipping candidates

Partnership announcements or licensing deals that provide non-dilutive funding and validate platform technology

Cash runway updates and equity financing announcements (dilution risk with 14.08x current ratio suggesting ~2-3 years runway)

Macro Sensitivity
Economic Cycle

low - Clinical-stage biotech with no commercial operations is largely insulated from GDP fluctuations. Rare disease drug demand is non-discretionary once approved. However, economic downturns can impact: (1) biotech sector valuations and access to capital markets for future financings, (2) larger pharma partners' willingness to pursue business development deals, and (3) investor risk appetite for pre-revenue assets. The 96% six-month return suggests momentum-driven trading rather than fundamental economic sensitivity.

Interest Rates

Rising interest rates negatively impact valuation through higher discount rates applied to distant future cash flows (product revenues likely 3-5+ years out). Higher rates also increase opportunity cost of holding cash-burning, pre-revenue biotech versus fixed income. Conversely, the company's $50M+ cash balance benefits from higher yields on short-term investments. Financing costs are minimal given low debt/equity ratio of 0.15, but future equity raises become more expensive as biotech sector multiples compress in high-rate environments.

Key Risks

Clinical trial failure risk - Phase 2 data for ENTR-601-44 may not demonstrate sufficient efficacy or safety, which would significantly impair platform validation and stock value given single-asset concentration

Platform technology risk - EEV delivery mechanism may face unforeseen biological barriers, immunogenicity issues, or manufacturing scalability challenges that limit commercial viability across multiple programs

Regulatory pathway uncertainty for novel intracellular biologics - FDA may require extensive additional data or impose restrictive labeling that limits market potential

Investor Profile

growth - High-risk, high-reward clinical-stage biotech attracts speculative growth investors betting on binary clinical trial outcomes. The 96% six-month return and 26% three-month return indicate momentum traders are active. Institutional biotech specialists and venture capital crossover funds typically hold positions. Not suitable for value or income investors given negative earnings, no dividends, and distant profitability timeline. The -15.3% one-year return followed by sharp recent rally suggests event-driven volatility around data catalysts.

Watch on Earnings
ENTR-601-44 Phase 2 trial interim and final data readout dates and results (splicing biomarker correction, functional endpoints)Quarterly cash burn rate and total cash/equivalents balance (runway calculation)Clinical trial enrollment pace and any protocol amendments or regulatory feedbackBusiness development activity - partnership announcements, licensing deals, or acquisition interest
Health Radar
3 strong3 concern
46/100
Liquidity
13.90Strong
Leverage
0.18Strong
Coverage
0.0xConcern
ROE
-51.2%Concern
ROIC
-55.6%Concern
Cash
$90MStrong
ANALYST COVERAGE5 analysts
BUY
+213.5%upside to target
L $10.00
Med $20.00consensus
H $21.00
Buy
360%
Hold
240%
3 Buy (60%)2 Hold (40%)0 Sell (0%)
Full report →
Stock Health
Composite Score
3 of 5 signals bullish
5/10
Technicals
RSI RangeRSI 33 — Bearish momentum
Volume
Volume FlowDistribution — institutional selling
Fundamentals
Last EarningsBeat estimates
Analyst ConsensusBuy
LiquidityCurrent Ratio 13.90 — healthy liquidity
Upcoming Events
EEarnings Report · Before OpenMay 17, 2026
Tomorrow
DEx-Dividend DateAug 14, 2026
In 90 days
PDividend PaymentSep 18, 2026
In 125 days
Technicals
Technical SetupBEARISH
Technicals →

Trend

DowntrendGolden Cross · 50D leads 200D by 33.2%

-46.8% vs SMA 50 · -29.2% vs SMA 200

Momentum

RSI32.9
Momentum fading
MACD-1.61
Below zero — bearish pulse · compressing
Market Position
Price Levels
52W High
$16.45+157.8%
EMA 50
$11.13+74.5%
EMA 200
$9.32+46.1%
Current
$6.38
52W Low
$4.93-22.7%
52-Week RangeNear 52-week low
$4.9313th %ile$16.45
Squeeze SetupVolume-based
Distribution Pressure

Heavy distribution on elevated volume — institutions appear to be exiting. Squeeze setups unlikely while selling pressure persists.

20-Day Money Flow
Acc days:6
Dist days:4
Edge:+2 acc
Volume Context
Avg Vol (50D)365K
Recent Vol (5D)
763K+109%

Based on volume distribution analysis. Direct short interest data (short float %, days to cover) is not available in current data sources.

Earnings & Analysts

ANALYST ESTIMATES

Consensus of 6 analysts
Analyst revisions:EPS↑ Revised UpRevenue↑ Revised Up

Analyst consensus estimates · Actuals replace estimates as reported

YearRevenue Est.Rev GthEPS Est.EPS GthRangeAnalysts
FY2025
$30.5M
$29.5M$31.9M
-$3.61
±14%
High5
FY2026(current)
$19.5M
$977847$55.6M
-35.9%-$3.96
±11%
High6
FY2027
$29.2M
$3.8M$54.6M
+49.6%-$3.58
±24%
High6
Range confidence:Tight (high)ModerateWide (low)
Earnings HistoryTRDA
Last 8Q
+152.7%avg beat
Beat 6 of 8 quartersMissed 2 Estimates falling
+1007%
Q3'24
+48%
Q4'24
+105%
Q1'25
+46%
Q2'25
-21%
Q3'25
-2%
Q4'25
+29%
Q1'26
+10%
Q2'26
Beat
Miss
Estimate
Deeper color = bigger beat/miss
* Negative EPS shown at reduced height
Analyst Activity
All ratings →
Analysts turning cautious
30d01
90d01
H.C. WainwrightBuy → Neutral
May 8
DOWNGRADE
Insider Activity
SEC Filings →
0 Buys/6 SellsNet Selling
NET SELLERS$0 bought · $629K sold · 30d window
Sethuraman NatarajanPresident, Res…
$399K
May 4
SELL
Dowden Nathan JPresident & COO
$230K
May 4
SELL
Wentworth Kory JamesCFO
$32K
Apr 1
SELL
Dowden Nathan JPresident & COO
$41K
Mar 9
SELL
Dowden Nathan JPresident & COO
$155K
Mar 10
SELL
Wentworth Kory JamesCFO
$66K
Mar 9
SELL
Financials

INSTITUTIONAL OWNERSHIP

1
BAKER BROS. ADVISORS LP
5.1M
2
5AM Venture Management, LLC
4.1M
3
BlackRock, Inc.
2.4M
4
TCG Crossover Management, LLC
2.3M
5
WELLINGTON MANAGEMENT GROUP LLP
1.0M
6
StepStone Group LP
761K
7
GEODE CAPITAL MANAGEMENT, LLC
667K
8
STATE STREET CORP
534K
News & Activity

TRDA News

20 articles · 4h ago

About

entrada therapeutics is building the leading intracellular biologics company to transform the treatment of devastating diseases. entrada was co-founded in 2016 by 5am ventures, a leading life sciences venture capital firm.

Industry
Research and Development in Biotechnology (except Nanobiotechnology)
Natarajan SethuramanPresident of Research & Development
Kevin HealySenior Vice President of Regulatory Affairs
Nathan J. DowdenPresident & Chief Operating Officer
PeersHealth Care(7 companies)
Screen sector →
SymbolPriceDay %Mkt CapP/ERev GrwMarginELO
TRDA
$6.38-6.59%$248M-8794.0%-56547.7%1500
$66.13-5.07%$13.0B+12626.1%-14525.8%1500
$94.92-3.79%$12.6B+3288.2%-4239.0%1500
$523.69-3.00%$12.1B+43205.3%-3008.0%1500
$227.72-1.30%$11.7B+6554.5%-2868.8%1500
$57.90-0.86%$11.2B50.3+1459.3%147.7%1500
$76.67-3.79%$10.8B+2325815.3%-19.7%1500
Sector avg-3.48%50.3+340593.5%-11580.2%1500