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Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data
| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| TCG Crossover Management, LLC | 5.67M | Jun 30, 26 | -- | 10.47% |
| FMR LLC | 4.93M | Jun 30, 26 | +3.39M | 9.10% |
| FCPM III SERVICES B.V. | 4.12M | Jun 30, 26 | -- | 7.60% |
| BlackRock, Inc. | 3.47M | Jun 30, 26 | +2.67M | 6.40% |
| VR Adviser, LLC | 3.04M | Jun 30, 26 | -- | 5.61% |
| STATE STREET CORP | 2.62M | Jun 30, 26 | +1.50M | 4.83% |
| Frazier Life Sciences Management, L.P. | 2.54M | Jun 30, 26 | -- | 4.69% |
| RA CAPITAL MANAGEMENT, L.P. | 2.40M | Jun 30, 26 | -3.00M | 4.43% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.08M | Jun 30, 26 | +651.05K | 3.85% |
| Caligan Partners LP | 1.93M | Jun 30, 26 | -- | 3.55% |
| Paradigm Biocapital Advisors LP | 1.75M | Jun 30, 26 | -- | 3.23% |
| GREAT POINT PARTNERS LLC | 1.70M | Jun 30, 26 | -50.00K | 3.14% |
| GEODE CAPITAL MANAGEMENT, LLC | 1.06M | Jun 30, 26 | +719.90K | 1.96% |
| NEXTBio Capital Management LP | 889.16K | Jun 30, 26 | -110.80K | 1.64% |
| Nantahala Capital Management, LLC | 845.00K | Jun 30, 26 | +845.00K | 1.56% |
| ADAR1 Capital Management, LLC | 680.63K | Jun 30, 26 | +680.63K | 1.26% |
| Logos Global Management LP | 650.00K | Jun 30, 26 | -100.00K | 1.20% |
| Rosalind Advisors, Inc. | 648.60K | Jun 30, 26 | -51.40K | 1.20% |
| NAN FUNG TRINITY (HK) Ltd | 646.55K | Jun 30, 26 | +646.55K | 1.19% |
| BRAIDWELL LP | 573.10K | Jun 30, 26 | +106.33K | 1.06% |
| BOOTHBAY FUND MANAGEMENT, LLC | 558.70K | Jun 30, 26 | +3.00K | 1.03% |
| UBS Group AG | 493.28K | Jun 30, 26 | +4.91K | 0.91% |
| MILLENNIUM MANAGEMENT LLC | 428.07K | Jun 30, 26 | +169.48K | 0.79% |
| SPHERA FUNDS MANAGEMENT LTD. | 416.42K | Jun 30, 26 | +94.50K | 0.77% |
| Woodline Partners LP | 379.72K | Jun 30, 26 | +379.72K | 0.70% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 340.36K | Jun 30, 26 | +340.36K | 0.63% |
| GOLDMAN SACHS GROUP INC | 328.89K | Jun 30, 26 | +67.00K | 0.61% |
| NORTHERN TRUST CORP | 328.74K | Jun 30, 26 | +264.19K | 0.61% |
| VANGUARD FIDUCIARY TRUST CO | 300.70K | Jun 30, 26 | +115.19K | 0.55% |
| Clearline Capital LP | 285.28K | Jun 30, 26 | -40.89K | 0.53% |
| BANK OF AMERICA CORP /DE/ | 177.74K | Jun 30, 26 | +64.85K | 0.33% |
| CITADEL ADVISORS LLC | 160.41K | Jun 30, 26 | +11.65K | 0.30% |
| Eversept Partners, LP | 149.68K | Jun 30, 26 | +149.68K | 0.28% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 121.40K | Jun 30, 26 | +99.18K | 0.22% |
| Sixth Street Partners Management Company, L.P. | 121.40K | Jun 30, 26 | +121.40K | 0.22% |
| Bank of New York Mellon Corp | 97.72K | Jun 30, 26 | +97.72K | 0.18% |
| MARSHALL WACE, LLP | 95.64K | Jun 30, 26 | -1.06M | 0.18% |
| Nuveen, LLC | 94.81K | Jun 30, 26 | +94.81K | 0.17% |
| AXIOM INVESTORS LLC /DE | 92.11K | Jun 30, 26 | -3.64K | 0.17% |
| XTX Topco Ltd | 82.64K | Jun 30, 26 | +82.64K | 0.15% |
| Jump Financial, LLC | 70.89K | Jun 30, 26 | -102.14K | 0.13% |
| Invesco Ltd. | 68.30K | Jun 30, 26 | +56.70K | 0.13% |
| CITIGROUP INC | 63.13K | Jun 30, 26 | +57.76K | 0.12% |
| MORGAN STANLEY | 61.56K | Jun 30, 26 | -55.16K | 0.11% |
| RHUMBLINE ADVISERS | 57.53K | Jun 30, 26 | +57.53K | 0.11% |
| ALPS ADVISORS INC | 55.00K | Jun 30, 26 | +55.00K | 0.10% |
| D. E. Shaw & Co., Inc. | 54.67K | Jun 30, 26 | +54.67K | 0.10% |
| JOHNSON & JOHNSON | 53.73K | Jun 30, 26 | -- | 0.10% |
| Rafferty Asset Management, LLC | 48.82K | Jun 30, 26 | -1.69K | 0.09% |
| Walleye Capital LLC | 46.61K | Jun 30, 26 | +46.61K | 0.09% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 41.81K | Jun 30, 26 | +41.81K | 0.08% |
| DEUTSCHE BANK AG\ | 40.35K | Jun 30, 26 | +40.35K | 0.07% |
| ALLIANCEBERNSTEIN L.P. | 37.21K | Jun 30, 26 | +37.21K | 0.07% |
| TWO SIGMA INVESTMENTS, LP | 37.01K | Jun 30, 26 | +37.01K | 0.07% |
| Engineers Gate Manager LP | 36.95K | Jun 30, 26 | +10.07K | 0.07% |
| WELLS FARGO & COMPANY/MN | 36.27K | Jun 30, 26 | +36.27K | 0.07% |
| RENAISSANCE TECHNOLOGIES LLC | 33.01K | Jun 30, 26 | -95.83K | 0.06% |
| Jefferies Financial Group Inc. | 32.66K | Jun 30, 26 | +32.66K | 0.06% |
| WELLINGTON MANAGEMENT GROUP LLP | 27.10K | Jun 30, 26 | +27.10K | 0.05% |
| Sarissa Capital Management LP | 25.40K | Jun 30, 26 | -- | 0.05% |
| PROFUND ADVISORS LLC | 24.59K | Jun 30, 26 | +2.58K | 0.05% |
| MetLife Investment Management, LLC | 24.44K | Jun 30, 26 | +24.44K | 0.05% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 24.38K | Jun 30, 26 | +20.87K | 0.04% |
| Squarepoint Ops LLC | 23.23K | Jun 30, 26 | -2.25K | 0.04% |
| SEI INVESTMENTS CO | 23.02K | Jun 30, 26 | +9.30K | 0.04% |
| Virtus Investment Advisers, Inc. | 22.79K | Jun 30, 26 | +22.79K | 0.04% |
| JPMORGAN CHASE & CO | 21.62K | Jun 30, 26 | +17.26K | 0.04% |
| TUDOR INVESTMENT CORP ET AL | 19.62K | Jun 30, 26 | -132.95K | 0.04% |
| Scientech Research LLC | 18.83K | Jun 30, 26 | +3.78K | 0.03% |
| Vanguard Global Advisers, LLC | 17.95K | Jun 30, 26 | +5.07K | 0.03% |
| Y-Intercept (Hong Kong) Ltd | 17.24K | Jun 30, 26 | +17.24K | 0.03% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 16.45K | Jun 30, 26 | -216.15K | 0.03% |
| FOX RUN MANAGEMENT, L.L.C. | 15.30K | Jun 30, 26 | +15.30K | 0.03% |
| BARCLAYS PLC | 14.56K | Jun 30, 26 | +14.43K | 0.03% |
| NEW YORK STATE COMMON RETIREMENT FUND | 14.30K | Jun 30, 26 | +14.30K | 0.03% |
| Shay Capital LLC | 13.70K | Jun 30, 26 | +13.70K | 0.03% |
| Police & Firemen's Retirement System of New Jersey | 12.04K | Jun 30, 26 | +12.04K | 0.02% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 10.79K | Jun 30, 26 | +10.79K | 0.02% |
| EntryPoint Capital, LLC | 10.79K | Jun 30, 26 | +10.79K | 0.02% |
| BNP PARIBAS ARBITRAGE, SNC | 10.71K | Jun 30, 26 | +7.86K | 0.02% |
| China Universal Asset Management Co., Ltd. | 8.62K | Jun 30, 26 | +1.26K | 0.02% |
| Legal & General Group Plc | 8.01K | Jun 30, 26 | +8.01K | 0.01% |
| Ameritas Investment Partners, Inc. | 3.70K | Jun 30, 26 | +3.70K | 0.01% |
| Russell Investments Group, Ltd. | 3.26K | Jun 30, 26 | +3.26K | 0.01% |
| GROUP ONE TRADING, L.P. | 2.96K | Jun 30, 26 | -6.10K | 0.01% |
| Mirae Asset Global Investments Co., Ltd. | 2.42K | Jun 30, 26 | +257 | 0.00% |
| Global Retirement Partners, LLC | 2.09K | Jun 30, 26 | +2.09K | 0.00% |
| Pinnacle Wealth Planning Services, Inc. | 1.98K | Jun 30, 26 | +1.98K | 0.00% |
| Tower Research Capital LLC (TRC) | 1.74K | Jun 30, 26 | -1.73K | 0.00% |
| Winthrop Capital Management, LLC | 1.48K | Jun 30, 26 | +1.48K | 0.00% |
| ROYAL BANK OF CANADA | 1.26K | Jun 30, 26 | +1.06K | 0.00% |
| GF FUND MANAGEMENT CO. LTD. | 1.07K | Jun 30, 26 | +700 | 0.00% |
| Pacer Advisors, Inc. | 815 | Jun 30, 26 | +815 | 0.00% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 562 | Jun 30, 26 | +562 | 0.00% |
| Sterling Capital Management LLC | 355 | Jun 30, 26 | +355 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | 308 | Jun 30, 26 | +62 | 0.00% |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 180 | Jun 30, 26 | +180 | 0.00% |
| SIGNATUREFD, LLC | 147 | Jun 30, 26 | +108 | 0.00% |
| MERCER GLOBAL ADVISORS INC /ADV | 68 | Jun 30, 26 | +68 | 0.00% |
| WPG Advisers, LLC | 22 | Jun 30, 26 | +1 | 0.00% |
| Allworth Financial LP | 10 | Jun 30, 26 | -63 | 0.00% |
| Parallel Advisors, LLC | 5 | Jun 30, 26 | -43 | 0.00% |
| SBI Securities Co., Ltd. | 3 | Jun 30, 26 | -- | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 2 | Jun 30, 26 | +2 | 0.00% |
| Quadrature Capital Ltd | -- | Jun 30, 26 | -76.63K | -- |
| Diametric Capital, LP | -- | Jun 30, 26 | -10.07K | -- |
| Simplify Asset Management Inc. | -- | Jun 30, 26 | -53.51K | -- |
| MAI Capital Management | -- | Jun 30, 26 | -40 | -- |
| Cannon Global Investment Management, LLC | -- | Jun 30, 26 | -11.70K | -- |
| AXQ CAPITAL, LP | -- | Jun 30, 26 | -15.02K | -- |
| Bollard Group LLC | -- | Jun 30, 26 | -23.99K | -- |
| INDEPENDENT FINANCIAL GROUP, LLC | -- | Jun 30, 26 | -13.97K | -- |
| Fortitude Family Office, LLC | -- | Jun 30, 26 | -31 | -- |
| Laurion Capital Management LP | -- | Jun 30, 26 | -318.67K | -- |
| Propel Bio Management, LLC | -- | Jun 30, 26 | -314.54K | -- |
| WINTON GROUP Ltd | -- | Jun 30, 26 | -11.87K | -- |
| Irenic Capital Management LP | -- | Jun 30, 26 | -32.66K | -- |
| Brevan Howard Capital Management LP | -- | Jun 30, 26 | -42.22K | -- |
| Ameritas Advisory Services, LLC | -- | Jun 30, 26 | -37 | -- |
| JANE STREET GROUP, LLC | -- | Jun 30, 26 | -75.89K | -- |
| Quantbot Technologies LP | -- | Jun 30, 26 | -307 | -- |
| VANGUARD GROUP INC | 770.25K | Dec 31, 25 | +665.06K | 1.42% |
| COWEN AND COMPANY, LLC | 1.22M | Sep 30, 24 | +1.22M | 2.25% |
| BlackRock Inc. | 497.70K | Jun 30, 24 | -1.75M | 0.92% |
| OUP Management Co., LLC | 374.71K | Sep 30, 23 | -- | 0.69% |
| Amalgamated Financial Corp. | 2.38K | Mar 31, 22 | +2.38K | 0.00% |
| PARAMETRIC PORTFOLIO ASSOCIATES LLC | -- | Mar 31, 22 | -21.65K | -- |
| Johnson & Johnson Innovation - JJDC, Inc. | 1.07M | Jun 30, 21 | -- | 1.98% |
