ZYME(ZYME)
ZYME
Institutional Ownership
Top 332 Institutional Holders
| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| EcoR1 Capital, LLC | 22.97M | Mar 31, 26 | -- | 31.22% |
| Rubric Capital Management LP | 7.00M | Mar 31, 26 | +1.25M | 9.51% |
| BlackRock, Inc. | 4.55M | Mar 31, 26 | -41.66K | 6.19% |
| BVF INC/IL | 3.73M | Mar 31, 26 | -204.50K | 5.08% |
| PERCEPTIVE ADVISORS LLC | 3.51M | Mar 31, 26 | +248.23K | 4.77% |
| MORGAN STANLEY | 2.48M | Mar 31, 26 | -112.51K | 3.37% |
| BNP Paribas Asset Management Holding S.A. | 1.91M | Mar 31, 26 | +85.99K | 2.59% |
| CITADEL ADVISORS LLC | 1.15M | Mar 31, 26 | +894.67K | 1.56% |
| DIMENSIONAL FUND ADVISORS LP | 1.14M | Mar 31, 26 | -20.08K | 1.55% |
| Nextech Invest, Ltd. | 1.11M | Mar 31, 26 | -- | 1.51% |
| STATE STREET CORP | 1.01M | Mar 31, 26 | -25.86K | 1.38% |
| Capricorn Fund Managers Ltd | 1.01M | Mar 31, 26 | -15.63K | 1.37% |
| DEUTSCHE BANK AG\ | 921.25K | Mar 31, 26 | -674.58K | 1.25% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 743.90K | Mar 31, 26 | +43.90K | 1.01% |
| Assenagon Asset Management S.A. | 727.99K | Mar 31, 26 | +80.61K | 0.99% |
| FMR LLC | 667.15K | Mar 31, 26 | +107.07K | 0.91% |
| GEODE CAPITAL MANAGEMENT, LLC | 659.94K | Mar 31, 26 | +11.97K | 0.90% |
| Nuveen, LLC | 651.66K | Mar 31, 26 | +3.34K | 0.89% |
| GOLDMAN SACHS GROUP INC | 599.49K | Mar 31, 26 | +179.28K | 0.81% |
| BioImpact Capital LLC | 565.25K | Mar 31, 26 | +565.25K | 0.77% |
| Prosight Management, LP | 539.05K | Mar 31, 26 | +8.66K | 0.73% |
| Qube Research & Technologies Ltd | 511.94K | Mar 31, 26 | +37.65K | 0.70% |
| Redmile Group, LLC | 491.65K | Mar 31, 26 | -- | 0.67% |
| Hillsdale Investment Management Inc. | 345.62K | Mar 31, 26 | +107.70K | 0.47% |
| SummitTX Capital, L.P. | 321.43K | Mar 31, 26 | +97.16K | 0.44% |
| NORTHERN TRUST CORP | 320.21K | Mar 31, 26 | +12.23K | 0.44% |
| UBS ASSET MANAGEMENT AMERICAS INC | 319.38K | Mar 31, 26 | -876 | 0.43% |
| ROYCE & ASSOCIATES LP | 299.20K | Mar 31, 26 | +299.20K | 0.41% |
| PICTON MAHONEY ASSET MANAGEMENT | 256.69K | Mar 31, 26 | +11.89K | 0.35% |
| Granahan Investment Management, LLC | 250.77K | Mar 31, 26 | +26.36K | 0.34% |
| HRT FINANCIAL LP | 237.89K | Mar 31, 26 | +116.83K | 0.32% |
| D. E. Shaw & Co., Inc. | 235.62K | Mar 31, 26 | +11.84K | 0.32% |
| JANE STREET GROUP, LLC | 226.97K | Mar 31, 26 | +156.52K | 0.31% |
| PANAGORA ASSET MANAGEMENT INC | 206.85K | Mar 31, 26 | +128.52K | 0.28% |
| Man Group plc | 189.89K | Mar 31, 26 | +114.57K | 0.26% |
| WELLS FARGO & COMPANY/MN | 189.64K | Mar 31, 26 | -18.68K | 0.26% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 185.12K | Mar 31, 26 | -35.78K | 0.25% |
| FEDERATED HERMES, INC. | 182.41K | Mar 31, 26 | +29.72K | 0.25% |
| RAYMOND JAMES FINANCIAL INC | 176.41K | Mar 31, 26 | -11.27K | 0.24% |
| UBS Group AG | 171.78K | Mar 31, 26 | -107.08K | 0.23% |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 163.65K | Mar 31, 26 | -18.14K | 0.22% |
| KENNEDY CAPITAL MANAGEMENT LLC | 148.23K | Mar 31, 26 | +2.69K | 0.20% |
| XTX Topco Ltd | 143.88K | Mar 31, 26 | +50.41K | 0.20% |
| DIADEMA PARTNERS LP | 142.13K | Mar 31, 26 | +142.13K | 0.19% |
| WELLINGTON MANAGEMENT GROUP LLP | 138.69K | Mar 31, 26 | -43.02K | 0.19% |
| Invesco Ltd. | 125.63K | Mar 31, 26 | -131.95K | 0.17% |
| Bank of New York Mellon Corp | 124.11K | Mar 31, 26 | -4.03K | 0.17% |
| CITIGROUP INC | 114.33K | Mar 31, 26 | +3.12K | 0.16% |
| JPMORGAN CHASE & CO | 114.07K | Mar 31, 26 | +79.06K | 0.16% |
| PLATINUM INVESTMENT MANAGEMENT LTD | 105.18K | Mar 31, 26 | -- | 0.14% |
| TEMA ETFS LLC | 104.93K | Mar 31, 26 | +28.96K | 0.14% |
| Toroso Investments, LLC | 104.93K | Mar 31, 26 | +104.93K | 0.14% |
| Fisher Asset Management, LLC | 101.44K | Mar 31, 26 | +33.24K | 0.14% |
| Susquehanna Portfolio Strategies, LLC | 99.80K | Mar 31, 26 | -- | 0.14% |
| AQR CAPITAL MANAGEMENT LLC | 90.67K | Mar 31, 26 | -406 | 0.12% |
| KORNITZER CAPITAL MANAGEMENT INC /KS | 88.80K | Mar 31, 26 | -- | 0.12% |
| VANGUARD FIDUCIARY TRUST CO | 84.40K | Mar 31, 26 | +84.40K | 0.11% |
| Squarepoint Ops LLC | 83.15K | Mar 31, 26 | +83.15K | 0.11% |
| MACKENZIE FINANCIAL CORP | 82.73K | Mar 31, 26 | +37.27K | 0.11% |
| Verdad Advisers, LP | 82.70K | Mar 31, 26 | +82.70K | 0.11% |
| PRINCIPAL FINANCIAL GROUP INC | 78.55K | Mar 31, 26 | +78.55K | 0.11% |
| FRANKLIN RESOURCES INC | 77.66K | Mar 31, 26 | +18.67K | 0.11% |
| STIFEL FINANCIAL CORP | 76.76K | Mar 31, 26 | +909 | 0.10% |
| RHUMBLINE ADVISERS | 75.40K | Mar 31, 26 | -99 | 0.10% |
| CREDIT AGRICOLE S A | 75.00K | Mar 31, 26 | -- | 0.10% |
| AMERIPRISE FINANCIAL INC | 74.22K | Mar 31, 26 | -38.92K | 0.10% |
| Swiss National Bank | 74.20K | Mar 31, 26 | -- | 0.10% |
| AMERICAN CENTURY COMPANIES INC | 70.85K | Mar 31, 26 | +12.02K | 0.10% |
| STATE OF WISCONSIN INVESTMENT BOARD | 66.11K | Mar 31, 26 | -9.46K | 0.09% |
| Dana Investment Advisors, Inc. | 56.11K | Mar 31, 26 | +7.79K | 0.08% |
| ALLIANCEBERNSTEIN L.P. | 55.90K | Mar 31, 26 | +5.87K | 0.08% |
| Campbell & CO Investment Adviser LLC | 54.88K | Mar 31, 26 | +21.30K | 0.07% |
| Russell Investments Group, Ltd. | 47.45K | Mar 31, 26 | -10.90K | 0.06% |
| ROYAL BANK OF CANADA | 47.36K | Mar 31, 26 | -7.70K | 0.06% |
| North Growth Management Ltd. | 46.00K | Mar 31, 26 | +1.00K | 0.06% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 42.79K | Mar 31, 26 | +42.79K | 0.06% |
| VICTORY CAPITAL MANAGEMENT INC | 42.40K | Mar 31, 26 | -501 | 0.06% |
| ENVESTNET ASSET MANAGEMENT INC | 40.42K | Mar 31, 26 | -393 | 0.05% |
| Manatuck Hill Partners, LLC | 40.00K | Mar 31, 26 | +40.00K | 0.05% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 39.75K | Mar 31, 26 | +39.36K | 0.05% |
| Quantinno Capital Management LP | 39.64K | Mar 31, 26 | +10.76K | 0.05% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 39.35K | Mar 31, 26 | +18.93K | 0.05% |
| Connor, Clark & Lunn Investment Management Ltd. | 37.92K | Mar 31, 26 | +37.92K | 0.05% |
| HSBC HOLDINGS PLC | 37.78K | Mar 31, 26 | +19.91K | 0.05% |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | 37.13K | Mar 31, 26 | -5.92K | 0.05% |
| TUDOR INVESTMENT CORP ET AL | 36.88K | Mar 31, 26 | +6.55K | 0.05% |
| HighTower Advisors, LLC | 36.26K | Mar 31, 26 | +36.26K | 0.05% |
| Persistent Asset Partners Ltd | 35.94K | Mar 31, 26 | +28.59K | 0.05% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 35.49K | Mar 31, 26 | +6.70K | 0.05% |
| HighVista Strategies LLC | 34.09K | Mar 31, 26 | +34.09K | 0.05% |
| MARTINGALE ASSET MANAGEMENT L P | 32.76K | Mar 31, 26 | +32.76K | 0.04% |
| Creative Planning | 32.39K | Mar 31, 26 | +4.10K | 0.04% |
| MARSHALL WACE, LLP | 32.22K | Mar 31, 26 | +32.22K | 0.04% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 31.59K | Mar 31, 26 | +14.16K | 0.04% |
| Engineers Gate Manager LP | 31.55K | Mar 31, 26 | +31.55K | 0.04% |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 30.43K | Mar 31, 26 | -2.38K | 0.04% |
| STRS OHIO | 30.10K | Mar 31, 26 | +3.50K | 0.04% |
| MetLife Investment Management, LLC | 29.65K | Mar 31, 26 | +1.02K | 0.04% |
| JOURNEY STRATEGIC WEALTH LLC | 29.05K | Mar 31, 26 | -- | 0.04% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 28.35K | Mar 31, 26 | -69.56K | 0.04% |
| BNP PARIBAS ARBITRAGE, SNC | 28.12K | Mar 31, 26 | +4.82K | 0.04% |
| OXFORD ASSET MANAGEMENT LLP | 27.81K | Mar 31, 26 | +27.81K | 0.04% |
| ExodusPoint Capital Management, LP | 27.37K | Mar 31, 26 | +27.37K | 0.04% |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 27.35K | Mar 31, 26 | -729 | 0.04% |
| VANGUARD ASSET MANAGEMENT, Ltd | 26.28K | Mar 31, 26 | +26.28K | 0.04% |
| Legal & General Group Plc | 26.21K | Mar 31, 26 | -5.94K | 0.04% |
| COMMONWEALTH EQUITY SERVICES, LLC | 26.03K | Mar 31, 26 | -64 | 0.04% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 24.42K | Mar 31, 26 | -151.67K | 0.03% |
| RITHOLTZ WEALTH MANAGEMENT | 24.24K | Mar 31, 26 | -95 | 0.03% |
| Vinva Investment Management Ltd | 24.09K | Mar 31, 26 | +11.87K | 0.03% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 23.37K | Mar 31, 26 | +264 | 0.03% |
| Headlands Technologies LLC | 22.84K | Mar 31, 26 | +22.84K | 0.03% |
| Duncan Williams Asset Management, LLC | 22.09K | Mar 31, 26 | -- | 0.03% |
| PRUDENTIAL FINANCIAL INC | 21.97K | Mar 31, 26 | +9.21K | 0.03% |
| GSA CAPITAL PARTNERS LLP | 20.51K | Mar 31, 26 | +20.51K | 0.03% |
| Jackson Creek Investment Advisors LLC | 18.70K | Mar 31, 26 | +18.70K | 0.03% |
| BARCLAYS PLC | 18.37K | Mar 31, 26 | -61.59K | 0.02% |
| JANUS HENDERSON GROUP PLC | 18.20K | Mar 31, 26 | -- | 0.02% |
| BANK OF MONTREAL /CAN/ | 17.47K | Mar 31, 26 | -- | 0.02% |
| NEW YORK STATE COMMON RETIREMENT FUND | 17.37K | Mar 31, 26 | -- | 0.02% |
| State of Wyoming | 17.15K | Mar 31, 26 | +6.27K | 0.02% |
| Quadrature Capital Ltd | 16.73K | Mar 31, 26 | -6.28K | 0.02% |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 15.34K | Mar 31, 26 | -- | 0.02% |
| AGF MANAGEMENT LTD | 15.00K | Mar 31, 26 | -- | 0.02% |
| Police & Firemen's Retirement System of New Jersey | 13.70K | Mar 31, 26 | -- | 0.02% |
| China Universal Asset Management Co., Ltd. | 13.28K | Mar 31, 26 | +1.08K | 0.02% |
| Freestone Grove Partners LP | 12.95K | Mar 31, 26 | +12.95K | 0.02% |
| State of New Jersey Common Pension Fund D | 12.79K | Mar 31, 26 | +12.79K | 0.02% |
| INTECH INVESTMENT MANAGEMENT LLC | 12.54K | Mar 31, 26 | -7.79K | 0.02% |
| Northwest & Ethical Investments L.P. | 12.24K | Mar 31, 26 | +200 | 0.02% |
| Abacus Wealth Partners, LLC | 11.67K | Mar 31, 26 | +1.45K | 0.02% |
| Janney Montgomery Scott LLC | 11.49K | Mar 31, 26 | +420 | 0.02% |
| JAMES INVESTMENT RESEARCH INC | 10.93K | Mar 31, 26 | -- | 0.01% |
| Ewing Morris & Co. Investment Partners Ltd. | 10.85K | Mar 31, 26 | -- | 0.01% |
| Virtus Investment Advisers, Inc. | 10.70K | Mar 31, 26 | +261 | 0.01% |
| LAZARD ASSET MANAGEMENT LLC | 10.60K | Mar 31, 26 | -3.17K | 0.01% |
| ProShare Advisors LLC | 10.57K | Mar 31, 26 | -1.81K | 0.01% |
| SG Americas Securities, LLC | 10.43K | Mar 31, 26 | -7.13K | 0.01% |
| Arizona State Retirement System | 10.28K | Mar 31, 26 | -118 | 0.01% |
| Soleus Capital Management, L.P. | 10.00K | Mar 31, 26 | -90.00K | 0.01% |
| Pictet Asset Management Holding SA | 9.26K | Mar 31, 26 | -64.37K | 0.01% |
| VOYA INVESTMENT MANAGEMENT LLC | 8.99K | Mar 31, 26 | -241 | 0.01% |
| Vanguard Investments Australia, Ltd. | 8.80K | Mar 31, 26 | +8.80K | 0.01% |
| Allspring Global Investments Holdings, LLC | 8.51K | Mar 31, 26 | +800 | 0.01% |
| WINTON GROUP Ltd | 8.40K | Mar 31, 26 | -2.78K | 0.01% |
| KLP KAPITALFORVALTNING AS | 8.00K | Mar 31, 26 | -- | 0.01% |
| CWM, LLC | 6.96K | Mar 31, 26 | -20 | 0.01% |
| Vanguard Global Advisers, LLC | 5.46K | Mar 31, 26 | +5.46K | 0.01% |
| Tower Research Capital LLC (TRC) | 4.87K | Mar 31, 26 | +3.52K | 0.01% |
| Ameritas Investment Partners, Inc. | 4.16K | Mar 31, 26 | -- | 0.01% |
| Mirae Asset Global Investments Co., Ltd. | 3.90K | Mar 31, 26 | +266 | 0.01% |
| DekaBank Deutsche Girozentrale | 3.84K | Mar 31, 26 | -- | 0.01% |
| EverSource Wealth Advisors, LLC | 2.67K | Mar 31, 26 | +2.49K | 0.00% |
| GF FUND MANAGEMENT CO. LTD. | 1.68K | Mar 31, 26 | +211 | 0.00% |
| Global Wealth Strategies & Associates | 1.64K | Mar 31, 26 | +1.64K | 0.00% |
| Sofinnova Investments, Inc. | 1.61K | Mar 31, 26 | +1.61K | 0.00% |
| TD Waterhouse Canada Inc. | 1.44K | Mar 31, 26 | +1.13K | 0.00% |
| SIMPLEX TRADING, LLC | 1.34K | Mar 31, 26 | -46.70K | 0.00% |
| Aviso Financial Inc. | 1.15K | Mar 31, 26 | +1.15K | 0.00% |
| GAMMA Investing LLC | 1.10K | Mar 31, 26 | +112 | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | 987 | Mar 31, 26 | +206 | 0.00% |
| Steward Partners Investment Advisory, LLC | 971 | Mar 31, 26 | +918 | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | 971 | Mar 31, 26 | +3 | 0.00% |
| Optiver Holding B.V. | 958 | Mar 31, 26 | -190 | 0.00% |
| ADVISOR GROUP HOLDINGS, INC. | 882 | Mar 31, 26 | -1.63K | 0.00% |
| NBC SECURITIES, INC. | 623 | Mar 31, 26 | -- | 0.00% |
| Federation des caisses Desjardins du Quebec | 570 | Mar 31, 26 | -- | 0.00% |
| NATIONAL BANK OF CANADA /FI/ | 554 | Mar 31, 26 | +9 | 0.00% |
| UMB Bank, n.a. | 466 | Mar 31, 26 | -- | 0.00% |
| JONES FINANCIAL COMPANIES LLLP | 465 | Mar 31, 26 | +445 | 0.00% |
| Parallel Advisors, LLC | 352 | Mar 31, 26 | +23 | 0.00% |
| US BANCORP \DE\ | 352 | Mar 31, 26 | +65 | 0.00% |
| HUNTINGTON NATIONAL BANK | 343 | Mar 31, 26 | -21 | 0.00% |
| Sterling Capital Management LLC | 324 | Mar 31, 26 | -7 | 0.00% |
| Caitong International Asset Management Co., Ltd | 216 | Mar 31, 26 | -1.18K | 0.00% |
| Allworth Financial LP | 109 | Mar 31, 26 | -37 | 0.00% |
| IFP Advisors, Inc | 96 | Mar 31, 26 | -- | 0.00% |
| HighMark Wealth Management LLC | 80 | Mar 31, 26 | -150 | 0.00% |
| ROTHSCHILD INVESTMENT LLC | 80 | Mar 31, 26 | +24 | 0.00% |
| Walleye Capital LLC | 78 | Mar 31, 26 | -13.59K | 0.00% |
| SIGNATUREFD, LLC | 77 | Mar 31, 26 | +35 | 0.00% |
| FIFTH THIRD BANCORP | 67 | Mar 31, 26 | +67 | 0.00% |
| Kilter Group LLC | 66 | Mar 31, 26 | -- | 0.00% |
| Bare Financial Services, Inc | 64 | Mar 31, 26 | -- | 0.00% |
| Rockefeller Capital Management L.P. | 61 | Mar 31, 26 | +61 | 0.00% |
| True Wealth Design, LLC | 58 | Mar 31, 26 | -- | 0.00% |
| Farther Finance Advisors, LLC | 57 | Mar 31, 26 | -222 | 0.00% |
| Physician Wealth Advisors, Inc. | 51 | Mar 31, 26 | -- | 0.00% |
| Versant Capital Management, Inc | 45 | Mar 31, 26 | +45 | 0.00% |
| Aster Capital Management (DIFC) Ltd | 42 | Mar 31, 26 | +42 | 0.00% |
| Covestor Ltd | 28 | Mar 31, 26 | -26 | 0.00% |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 25 | Mar 31, 26 | -- | 0.00% |
| TWIN PEAKS WEALTH ADVISORS, LLC | 20 | Mar 31, 26 | +20 | 0.00% |
| CoreCap Advisors, LLC | 18 | Mar 31, 26 | -- | 0.00% |
| Root Financial Partners, LLC | 12 | Mar 31, 26 | +12 | 0.00% |
| Smartleaf Asset Management LLC | 12 | Mar 31, 26 | -- | 0.00% |
| SBI Securities Co., Ltd. | 11 | Mar 31, 26 | -- | 0.00% |
| MAI Capital Management | 7 | Mar 31, 26 | +2 | 0.00% |
| Larson Financial Group LLC | 6 | Mar 31, 26 | -- | 0.00% |
| Hughes Financial Services, LLC | 4 | Mar 31, 26 | +4 | 0.00% |
| Quarry LP | -- | Mar 31, 26 | -90 | -- |
| AMALGAMATED BANK | -- | Mar 31, 26 | -1.57K | -- |
| Walleye Trading LLC | -- | Mar 31, 26 | -13.25K | -- |
| Daiwa Securities Group Inc. | -- | Mar 31, 26 | -186 | -- |
| Vestal Point Capital, LP | -- | Mar 31, 26 | -865.00K | -- |
| GROUP ONE TRADING, L.P. | -- | Mar 31, 26 | -8.84K | -- |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | -- | Mar 31, 26 | -663.55K | -- |
| Truvestments Capital LLC | -- | Mar 31, 26 | -231 | -- |
| NEOS Investment Management LLC | -- | Mar 31, 26 | -77.11K | -- |
| Skopos Labs, Inc. | -- | Mar 31, 26 | -8.02K | -- |
| SRS Capital Advisors, Inc. | -- | Mar 31, 26 | -169 | -- |
| MILLENNIUM MANAGEMENT LLC | -- | Mar 31, 26 | -381.62K | -- |
| ALGERT GLOBAL LLC | -- | Mar 31, 26 | -423.65K | -- |
| TANG CAPITAL MANAGEMENT LLC | -- | Mar 31, 26 | -34.63K | -- |
| Apollon Wealth Management, LLC | -- | Mar 31, 26 | -7.88K | -- |
| Schonfeld Strategic Advisors LLC | -- | Mar 31, 26 | -288.57K | -- |
| RENAISSANCE TECHNOLOGIES LLC | -- | Mar 31, 26 | -220.88K | -- |
| Y-Intercept (Hong Kong) Ltd | -- | Mar 31, 26 | -22.64K | -- |
| Siren, L.L.C. | -- | Mar 31, 26 | -1.68M | -- |
| THURSTON, SPRINGER, MILLER, HERD & TITAK, INC. | -- | Mar 31, 26 | -610 | -- |
| Brevan Howard Capital Management LP | -- | Mar 31, 26 | -23.33K | -- |
| Cresset Asset Management, LLC | -- | Mar 31, 26 | -8.12K | -- |
| Baader Bank Aktiengesellschaft | -- | Mar 31, 26 | -10.01K | -- |
| Aquatic Capital Management LLC | -- | Mar 31, 26 | -24.10K | -- |
| JUPITER ASSET MANAGEMENT LTD | -- | Mar 31, 26 | -125.51K | -- |
| CreativeOne Wealth, LLC | -- | Mar 31, 26 | -18.26K | -- |
| Opaleye Management Inc. | -- | Mar 31, 26 | -108.93K | -- |
| Trexquant Investment LP | -- | Mar 31, 26 | -101.27K | -- |
| ACUTA CAPITAL PARTNERS, LLC | -- | Mar 31, 26 | -80.14K | -- |
| Penserra Capital Management LLC | -- | Mar 31, 26 | -60.15K | -- |
| PERCEPTIVE ADVISORS LLC | 3.26M | Dec 31, 25 | +1.17M | 4.43% |
| MORGAN STANLEY | 2.59M | Dec 31, 25 | -1.39M | 3.52% |
| VANGUARD GROUP INC | 2.33M | Dec 31, 25 | +174.29K | 3.17% |
| Nextech Invest, Ltd. | 1.11M | Dec 31, 25 | -- | 1.51% |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 700.00K | Dec 31, 25 | +386.25K | 0.95% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 663.55K | Dec 31, 25 | +99.55K | 0.90% |
| FMR LLC | 560.09K | Dec 31, 25 | +556.57K | 0.76% |
| Prosight Management, LP | 530.39K | Dec 31, 25 | -219.22K | 0.72% |
| Redmile Group, LLC | 491.65K | Dec 31, 25 | -3.21M | 0.67% |
| Qube Research & Technologies Ltd | 474.29K | Dec 31, 25 | +219.29K | 0.64% |
| ALGERT GLOBAL LLC | 423.65K | Dec 31, 25 | +215.72K | 0.58% |
| GOLDMAN SACHS GROUP INC | 420.21K | Dec 31, 25 | -23.32K | 0.57% |
| NORTHERN TRUST CORP | 307.98K | Dec 31, 25 | -40.27K | 0.42% |
| CITADEL ADVISORS LLC | 255.35K | Dec 31, 25 | +48.49K | 0.35% |
| Granahan Investment Management, LLC | 224.41K | Dec 31, 25 | -120.92K | 0.31% |
| SummitTX Capital, L.P. | 224.27K | Dec 31, 25 | +224.27K | 0.30% |
| D. E. Shaw & Co., Inc. | 223.79K | Dec 31, 25 | +96.86K | 0.30% |
| RAYMOND JAMES FINANCIAL INC | 187.69K | Dec 31, 25 | +64.82K | 0.26% |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 181.79K | Dec 31, 25 | -91.01K | 0.25% |
| WELLINGTON MANAGEMENT GROUP LLP | 181.71K | Dec 31, 25 | +13.02K | 0.25% |
| KENNEDY CAPITAL MANAGEMENT LLC | 145.53K | Dec 31, 25 | -906 | 0.20% |
| HRT FINANCIAL LP | 121.06K | Dec 31, 25 | +52.60K | 0.16% |
| AMERIPRISE FINANCIAL INC | 113.14K | Dec 31, 25 | +37.21K | 0.15% |
| Opaleye Management Inc. | 108.93K | Dec 31, 25 | +8.93K | 0.15% |
| Trexquant Investment LP | 101.27K | Dec 31, 25 | +101.27K | 0.14% |
| Susquehanna Portfolio Strategies, LLC | 99.80K | Dec 31, 25 | +15.60K | 0.14% |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 97.91K | Dec 31, 25 | -63.58K | 0.13% |
| AQR CAPITAL MANAGEMENT LLC | 91.08K | Dec 31, 25 | -61.56K | 0.12% |
| BANK OF AMERICA CORP /DE/ | 89.52K | Dec 31, 25 | +14.20K | 0.12% |
| ACUTA CAPITAL PARTNERS, LLC | 80.14K | Dec 31, 25 | -- | 0.11% |
| BARCLAYS PLC | 79.97K | Dec 31, 25 | -119.06K | 0.11% |
| NEOS Investment Management LLC | 77.11K | Dec 31, 25 | +13.45K | 0.10% |
| STATE OF WISCONSIN INVESTMENT BOARD | 75.57K | Dec 31, 25 | +19.29K | 0.10% |
| Man Group plc | 75.32K | Dec 31, 25 | -83.30K | 0.10% |
| CREDIT AGRICOLE S A | 75.00K | Dec 31, 25 | +75.00K | 0.10% |
| AMERICAN CENTURY COMPANIES INC | 58.83K | Dec 31, 25 | +7.82K | 0.08% |
| ALLIANCEBERNSTEIN L.P. | 50.03K | Dec 31, 25 | -- | 0.07% |
| Dana Investment Advisors, Inc. | 48.32K | Dec 31, 25 | +48.32K | 0.07% |
| SIMPLEX TRADING, LLC | 48.04K | Dec 31, 25 | +19.28K | 0.07% |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37.76K | Dec 31, 25 | +2.53K | 0.05% |
| TANG CAPITAL MANAGEMENT LLC | 34.63K | Dec 31, 25 | -1.07M | 0.05% |
| TWO SIGMA ADVISERS, LP | 31.41K | Dec 31, 25 | +31.41K | 0.04% |
| Quantinno Capital Management LP | 28.88K | Dec 31, 25 | +28.88K | 0.04% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 28.78K | Dec 31, 25 | +1.97K | 0.04% |
| VIRGINIA RETIREMENT SYSTEMS ET AL | 27.93K | Dec 31, 25 | -28.04K | 0.04% |
| Aquatic Capital Management LLC | 24.10K | Dec 31, 25 | +24.10K | 0.03% |
| Brevan Howard Capital Management LP | 23.33K | Dec 31, 25 | +8.81K | 0.03% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 23.11K | Dec 31, 25 | +164 | 0.03% |
| Quadrature Capital Ltd | 23.02K | Dec 31, 25 | +23.02K | 0.03% |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20.42K | Dec 31, 25 | -9.29K | 0.03% |
| JANUS HENDERSON GROUP PLC | 18.20K | Dec 31, 25 | -- | 0.02% |
| LAZARD ASSET MANAGEMENT LLC | 13.78K | Dec 31, 25 | -1.53K | 0.02% |
| Vinva Investment Management Ltd | 12.22K | Dec 31, 25 | -2.38K | 0.02% |
| Northwest & Ethical Investments L.P. | 12.04K | Dec 31, 25 | +2.01K | 0.02% |
| Quest Partners LLC | 8.31K | Dec 31, 25 | -158 | 0.01% |
| Cresset Asset Management, LLC | 8.12K | Dec 31, 25 | -2.01K | 0.01% |
| CWM, LLC | 6.97K | Dec 31, 25 | +7 | 0.01% |
| Optiver Holding B.V. | 1.15K | Dec 31, 25 | -362 | 0.00% |
| Federation des caisses Desjardins du Quebec | 570 | Dec 31, 25 | -300 | 0.00% |
| NATIONAL BANK OF CANADA /FI/ | 545 | Dec 31, 25 | -4 | 0.00% |
| US BANCORP \DE\ | 287 | Dec 31, 25 | +39 | 0.00% |
| COMERICA BANK | 211 | Dec 31, 25 | -- | 0.00% |
| SRS Capital Advisors, Inc. | 169 | Dec 31, 25 | -2.81K | 0.00% |
| Allworth Financial LP | 146 | Dec 31, 25 | +6 | 0.00% |
| Sunbelt Securities, Inc. | 27 | Dec 31, 25 | -- | 0.00% |
| JONES FINANCIAL COMPANIES LLLP | 20 | Dec 31, 25 | +20 | 0.00% |
| Smartleaf Asset Management LLC | 12 | Dec 31, 25 | -- | 0.00% |
| MAI Capital Management | 5 | Dec 31, 25 | +5 | 0.00% |
| DLD Asset Management, LP | -- | Dec 31, 25 | -20.00K | -- |
| DARK FOREST CAPITAL MANAGEMENT LP | -- | Dec 31, 25 | -37.17K | -- |
| Ikarian Capital, LLC | -- | Dec 31, 25 | -72.79K | -- |
| BOOTHBAY FUND MANAGEMENT, LLC | -- | Dec 31, 25 | -32.76K | -- |
| AXA Investment Managers S.A. | 158.42K | Sep 30, 25 | +158.42K | 0.22% |
| SHELL ASSET MANAGEMENT CO | 4.21K | Sep 30, 25 | -5.08K | 0.01% |
| Point72 (DIFC) Ltd | -- | Sep 30, 25 | -77 | -- |
| Cubist Systematic Strategies, LLC | -- | Sep 30, 25 | -119.96K | -- |
| Point72 Asia (Singapore) Pte. Ltd. | -- | Sep 30, 25 | -6.31K | -- |
| Aquilo Capital Management, LLC | 84.48K | Mar 31, 25 | +84.48K | 0.11% |
| Lindbrook Capital, LLC | 371 | Mar 31, 25 | -- | 0.00% |
| Nextech Invest Ltd. | 1.11M | Dec 31, 24 | -- | 1.51% |
| Nuveen Asset Management, LLC | 207.02K | Dec 31, 24 | +886 | 0.28% |
| WR Wealth Planners, LLC | 28 | Dec 31, 24 | -- | 0.00% |
| CAXTON ASSOCIATES LP | -- | Dec 31, 24 | -45.81K | -- |
| Virtus Fund Advisers, LLC | -- | Dec 31, 24 | -1.91K | -- |
| Raymond James Financial Services Advisors, Inc. | 55.51K | Sep 30, 24 | -1.87K | 0.08% |
| RAYMOND JAMES & ASSOCIATES | 17.90K | Sep 30, 24 | +1.02K | 0.02% |
| BlackRock Inc. | 4.19M | Jun 30, 24 | +97.85K | 5.70% |
| CREDIT SUISSE AG/ | 1.90M | Mar 31, 24 | -407.86K | 2.58% |
| Altitude Crest Partners Inc. | 145.58K | Mar 31, 24 | +145.58K | 0.20% |
| Grey Street Capital, LLC | 24.69K | Mar 31, 24 | +24.69K | 0.03% |
| Cutler Group LLC / CA | -- | Mar 31, 24 | -1.40K | -- |
| PUTNAM INVESTMENTS LLC | 70.00K | Dec 31, 23 | -2.22K | 0.10% |
| Point72 Middle East FZE | 10.44K | Dec 31, 23 | +10.44K | 0.01% |
| EA Series Trust | 228.37K | Jun 30, 23 | +228.37K | 0.31% |
| PICTET ASSET MANAGEMENT SA | -- | Jun 30, 23 | -14.67K | -- |
| MARINER INDEPENDENT ADVISOR NETWORK, LLC | 296.38K | Sep 30, 22 | +296.38K | 0.40% |
| Marshall Wace North America L.P. | 40.62K | Sep 30, 21 | +40.62K | 0.06% |
| KNOTT DAVID M | 4.00K | Sep 30, 21 | +4.00K | 0.01% |
| PICTET ASSET MANAGEMENT LTD | 1.06M | Jun 30, 21 | +297.38K | 1.44% |
| Winslow, Evans & Crocker, Inc. | 50 | Dec 31, 20 | -- | 0.00% |
| NumerixS Investment Technologies Inc | -- | Jun 30, 20 | -1.10K | -- |
| Advisor Group, Inc. | 227 | Dec 31, 19 | -1.08K | 0.00% |