Agios Pharmaceuticals, Inc.AGIONASDAQ
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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| DiNuzzo Private Wealth, Inc. | -- | Dec 31, 25 | -1 | -- |
| True Wealth Design, LLC | -- | Dec 31, 25 | -9 | -- |
| Phocas Financial Corp. | -- | Dec 31, 25 | -46.61K | -- |
| HALBERT HARGROVE GLOBAL ADVISORS, LLC | -- | Dec 31, 25 | -47 | -- |
| NBC SECURITIES, INC. | -- | Dec 31, 25 | -241 | -- |
| NORTHCAPE WEALTH MANAGEMENT, LLC | -- | Dec 31, 25 | -5.24K | -- |
| PEREGRINE CAPITAL MANAGEMENT LLC | -- | Dec 31, 25 | -162.91K | -- |
| FIFTH THIRD BANCORP | -- | Dec 31, 25 | -30 | -- |
| MATHER GROUP, LLC. | -- | Dec 31, 25 | -95 | -- |
| Spire Wealth Management | -- | Dec 31, 25 | -230 | -- |
| Savvy Advisors, Inc. | -- | Dec 31, 25 | -11.99K | -- |
| FARALLON CAPITAL MANAGEMENT LLC | 5.78M | Sep 30, 25 | +13.60K | -- |
| BlackRock, Inc. | 4.55M | Sep 30, 25 | -288.02K | -- |
| Bellevue Group AG | 3.71M | Sep 30, 25 | +124.59K | -- |
| Erste Asset Management GmbH | 2.76M | Sep 30, 25 | +438.41K | -- |
| Paradigm Biocapital Advisors LP | 2.67M | Sep 30, 25 | +1.53M | -- |
| WELLINGTON MANAGEMENT GROUP LLP | 2.47M | Sep 30, 25 | +2.05M | -- |
| COMMODORE CAPITAL LP | 2.34M | Sep 30, 25 | +13.29K | -- |
| STATE STREET CORP | 2.26M | Sep 30, 25 | +311.60K | -- |
| MACQUARIE GROUP LTD | 1.96M | Sep 30, 25 | +57.51K | -- |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.66M | Sep 30, 25 | -617.31K | -- |
| TCG Crossover Management, LLC | 1.43M | Sep 30, 25 | +733.04K | -- |
| GEODE CAPITAL MANAGEMENT, LLC | 1.42M | Sep 30, 25 | +10.56K | -- |
| Frazier Life Sciences Management, L.P. | 1.28M | Sep 30, 25 | -- | -- |
| Caligan Partners LP | 1.13M | Sep 30, 25 | +59.95K | -- |
| BANK OF AMERICA CORP /DE/ | 1.13M | Sep 30, 25 | +9.69K | -- |
| DIMENSIONAL FUND ADVISORS LP | 1.02M | Sep 30, 25 | -84.89K | -- |
| BNP Paribas Asset Management Holding S.A. | 987.34K | Sep 30, 25 | -29.55K | -- |
| Rock Springs Capital Management LP | 958.54K | Sep 30, 25 | -31.20K | -- |
| DEUTSCHE BANK AG\ | 926.73K | Sep 30, 25 | +5.15K | -- |
| Fisher Asset Management, LLC | 870.14K | Sep 30, 25 | -7.39K | -- |
| GW&K Investment Management, LLC | 852.94K | Sep 30, 25 | -15.68K | -- |
| GOLDMAN SACHS GROUP INC | 804.77K | Sep 30, 25 | +156.71K | -- |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 800.00K | Sep 30, 25 | +9.00K | -- |
| ARMISTICE CAPITAL, LLC | 764.00K | Sep 30, 25 | -404.00K | -- |
| ArrowMark Colorado Holdings LLC | 679.92K | Sep 30, 25 | +21.23K | -- |
| SCS Capital Management LLC | 598.76K | Sep 30, 25 | -5.32K | -- |
| NORTHERN TRUST CORP | 555.41K | Sep 30, 25 | -1.40K | -- |
| Connor, Clark & Lunn Investment Management Ltd. | 530.10K | Sep 30, 25 | +24.87K | -- |
| BALYASNY ASSET MANAGEMENT L.P. | 495.49K | Sep 30, 25 | +495.49K | -- |
| BOOTHBAY FUND MANAGEMENT, LLC | 495.34K | Sep 30, 25 | +48.32K | -- |
| CITADEL ADVISORS LLC | 491.98K | Sep 30, 25 | -589.49K | -- |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 482.19K | Sep 30, 25 | +6.14K | -- |
| MORGAN STANLEY | 417.00K | Sep 30, 25 | +125.03K | -- |
| Artisan Partners Limited Partnership | 402.94K | Sep 30, 25 | +12.96K | -- |
| JANE STREET GROUP, LLC | 395.12K | Sep 30, 25 | +361.63K | -- |
| D. E. Shaw & Co., Inc. | 367.75K | Sep 30, 25 | -228.45K | -- |
| Legal & General Group Plc | 322.93K | Sep 30, 25 | +258.63K | -- |
| Bank of New York Mellon Corp | 270.10K | Sep 30, 25 | +3.44K | -- |
| Palo Alto Investors LP | 265.50K | Sep 30, 25 | -3.29K | -- |
| SummitTX Capital, L.P. | 262.98K | Sep 30, 25 | +262.98K | -- |
| Eagle Health Investments LP | 246.23K | Sep 30, 25 | -84.60K | -- |
| MARSHALL WACE, LLP | 226.82K | Sep 30, 25 | -457.85K | -- |
| BARCLAYS PLC | 216.04K | Sep 30, 25 | +35.34K | -- |
| HighVista Strategies LLC | 195.30K | Sep 30, 25 | +125.17K | -- |
| BAKER BROS. ADVISORS LP | 189.87K | Sep 30, 25 | -- | -- |
| JPMORGAN CHASE & CO | 183.10K | Sep 30, 25 | -844.32K | -- |
| AXA Investment Managers S.A. | 177.68K | Sep 30, 25 | +177.68K | -- |
| Allianz Asset Management GmbH | 146.64K | Sep 30, 25 | +7.75K | -- |
| Alyeska Investment Group, L.P. | 146.51K | Sep 30, 25 | +146.51K | -- |
| AMERICAN CENTURY COMPANIES INC | 145.12K | Sep 30, 25 | +17.47K | -- |
| Patient Square Capital LP | 133.83K | Sep 30, 25 | -5.91K | -- |
| TD ASSET MANAGEMENT INC | 128.29K | Sep 30, 25 | -39.90K | -- |
| Vestal Point Capital, LP | 127.00K | Sep 30, 25 | +127.00K | -- |
| Ikarian Capital, LLC | 126.98K | Sep 30, 25 | +126.98K | -- |
| Invesco Ltd. | 126.98K | Sep 30, 25 | +14.36K | -- |
| Hudson Bay Capital Management LP | 122.50K | Sep 30, 25 | -7.50K | -- |
| Nuveen, LLC | 119.58K | Sep 30, 25 | -- | -- |
| UBS ASSET MANAGEMENT AMERICAS INC | 106.88K | Sep 30, 25 | -110.53K | -- |
| Swiss National Bank | 106.66K | Sep 30, 25 | -2.80K | -- |
| Parkman Healthcare Partners LLC | 100.38K | Sep 30, 25 | +100.38K | -- |
| Nantahala Capital Management, LLC | 100.00K | Sep 30, 25 | +100.00K | -- |
| PRUDENTIAL FINANCIAL INC | 98.24K | Sep 30, 25 | -60.12K | -- |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 96.01K | Sep 30, 25 | -36.07K | -- |
| AQR CAPITAL MANAGEMENT LLC | 91.64K | Sep 30, 25 | -5.26K | -- |
| Jump Financial, LLC | 87.90K | Sep 30, 25 | +87.90K | -- |
| RHUMBLINE ADVISERS | 87.70K | Sep 30, 25 | -2.18K | -- |
| FIRST TRUST ADVISORS LP | 74.43K | Sep 30, 25 | +38.00K | -- |
| Woodline Partners LP | 74.00K | Sep 30, 25 | -159.07K | -- |
| Rafferty Asset Management, LLC | 68.22K | Sep 30, 25 | +18.82K | -- |
| ALLIANCEBERNSTEIN L.P. | 61.50K | Sep 30, 25 | +33 | -- |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 61.30K | Sep 30, 25 | +13.64K | -- |
| TWO SIGMA INVESTMENTS, LP | 59.63K | Sep 30, 25 | +59.63K | -- |
| MOORE CAPITAL MANAGEMENT, LP | 55.00K | Sep 30, 25 | -25.00K | -- |
| NEW YORK STATE COMMON RETIREMENT FUND | 49.79K | Sep 30, 25 | +10.70K | -- |
| WELLS FARGO & COMPANY/MN | 44.75K | Sep 30, 25 | +7.06K | -- |
| CITIGROUP INC | 43.62K | Sep 30, 25 | -12.87K | -- |
| VIRGINIA RETIREMENT SYSTEMS ET AL | 41.06K | Sep 30, 25 | -8.60K | -- |
| AMERIPRISE FINANCIAL INC | 38.43K | Sep 30, 25 | -13.82K | -- |
| ADAR1 Capital Management, LLC | 37.00K | Sep 30, 25 | +1.10K | -- |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 36.59K | Sep 30, 25 | -2.99K | -- |
| ALGERT GLOBAL LLC | 35.77K | Sep 30, 25 | -53.06K | -- |
| STATE OF WISCONSIN INVESTMENT BOARD | 35.57K | Sep 30, 25 | -23.53K | -- |
| EDGEWOOD MANAGEMENT LLC | 35.00K | Sep 30, 25 | -- | -- |
| MetLife Investment Management, LLC | 34.03K | Sep 30, 25 | -- | -- |
| SEI INVESTMENTS CO | 32.30K | Sep 30, 25 | +21.97K | -- |
| VICTORY CAPITAL MANAGEMENT INC | 30.23K | Sep 30, 25 | +818 | -- |
| ALPS ADVISORS INC | 27.55K | Sep 30, 25 | -3.72K | -- |
| KENNEDY CAPITAL MANAGEMENT LLC | 24.64K | Sep 30, 25 | -12.06K | -- |
| JANUS HENDERSON GROUP PLC | 23.80K | Sep 30, 25 | -- | -- |
| INTECH INVESTMENT MANAGEMENT LLC | 23.58K | Sep 30, 25 | +785 | -- |
| FMR LLC | 20.71K | Sep 30, 25 | +2.12K | -- |
| GREAT WEST LIFE ASSURANCE CO /CAN/ | 20.32K | Sep 30, 25 | +662 | -- |
| Handelsbanken Fonder AB | 19.32K | Sep 30, 25 | -- | -- |
| ROYAL BANK OF CANADA | 17.53K | Sep 30, 25 | -5.64K | -- |
| Caption Management, LLC | 17.49K | Sep 30, 25 | +494 | -- |
| WINTON GROUP Ltd | 16.40K | Sep 30, 25 | +16.40K | -- |
| Rockefeller Capital Management L.P. | 16.04K | Sep 30, 25 | +16.04K | -- |
| GUGGENHEIM CAPITAL LLC | 15.90K | Sep 30, 25 | -2.00K | -- |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 15.85K | Sep 30, 25 | -- | -- |
| Police & Firemen's Retirement System of New Jersey | 15.63K | Sep 30, 25 | +2.71K | -- |
| Freestone Grove Partners LP | 15.42K | Sep 30, 25 | +15.42K | -- |
| PROFUND ADVISORS LLC | 15.11K | Sep 30, 25 | +4.26K | -- |
| Toroso Investments, LLC | 14.91K | Sep 30, 25 | -646 | -- |
| BNP PARIBAS ARBITRAGE, SNC | 14.70K | Sep 30, 25 | +2.79K | -- |
| TWO SIGMA ADVISERS, LP | 13.60K | Sep 30, 25 | +13.60K | -- |
| Atria Investments, Inc | 13.39K | Sep 30, 25 | -87 | -- |
| Creative Planning | 13.12K | Sep 30, 25 | +280 | -- |
| Virtus Investment Advisers, Inc. | 12.88K | Sep 30, 25 | -- | -- |
| Ensign Peak Advisors, Inc | 12.62K | Sep 30, 25 | -12.35K | -- |
| Brevan Howard Capital Management LP | 12.07K | Sep 30, 25 | -17.11K | -- |
| ProShare Advisors LLC | 11.73K | Sep 30, 25 | -2.02K | -- |
| Inspire Investing, LLC | 11.39K | Sep 30, 25 | -333 | -- |
| Gallagher Fiduciary Advisors, LLC | 11.26K | Sep 30, 25 | -213 | -- |
| OMERS ADMINISTRATION Corp | 11.20K | Sep 30, 25 | +11.20K | -- |
| VOYA INVESTMENT MANAGEMENT LLC | 10.13K | Sep 30, 25 | -5.27K | -- |
| Cinctive Capital Management LP | 10.10K | Sep 30, 25 | +10.10K | -- |
| ENVESTNET ASSET MANAGEMENT INC | 9.42K | Sep 30, 25 | -677 | -- |
| COMMERCE BANK | 9.16K | Sep 30, 25 | -445 | -- |
| Y-Intercept (Hong Kong) Ltd | 7.93K | Sep 30, 25 | +7.93K | -- |
| Savant Capital, LLC | 6.90K | Sep 30, 25 | +20 | -- |
| Russell Investments Group, Ltd. | 6.86K | Sep 30, 25 | -2.44K | -- |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 6.80K | Sep 30, 25 | -- | -- |
| Voleon Capital Management LP | 6.68K | Sep 30, 25 | +6.68K | -- |
| Point72 Asset Management, L.P. | 6.51K | Sep 30, 25 | +6.51K | -- |
| Cerity Partners LLC | 6.44K | Sep 30, 25 | -350 | -- |
| Cubist Systematic Strategies, LLC | 6.26K | Sep 30, 25 | +6.26K | -- |
| FIDUCIARY TRUST CO | 5.45K | Sep 30, 25 | +5.45K | -- |
| Quest Partners LLC | 5.41K | Sep 30, 25 | +4.74K | -- |
| MILLENNIUM MANAGEMENT LLC | 5.05K | Sep 30, 25 | -295.15K | -- |
| NORTH STAR ASSET MANAGEMENT INC | 5.00K | Sep 30, 25 | +5.00K | -- |
| Quarry LP | 5.00K | Sep 30, 25 | +5.00K | -- |
| Ameritas Investment Partners, Inc. | 4.72K | Sep 30, 25 | -1.19K | -- |
| PNC FINANCIAL SERVICES GROUP, INC. | 4.55K | Sep 30, 25 | +135 | -- |
| Sterling Capital Management LLC | 3.91K | Sep 30, 25 | +2.40K | -- |
| TORNO CAPITAL, LLC | 2.50K | Sep 30, 25 | +2.50K | -- |
| Quantbot Technologies LP | 1.98K | Sep 30, 25 | +1.98K | -- |
| AMALGAMATED BANK | 1.96K | Sep 30, 25 | -- | -- |
| BRYN MAWR TRUST Co | 1.70K | Sep 30, 25 | -186 | -- |
| BIT Capital GmbH | 1.57K | Sep 30, 25 | -659 | -- |
| Tower Research Capital LLC (TRC) | 1.36K | Sep 30, 25 | -5.08K | -- |
| NewEdge Advisors, LLC | 1.27K | Sep 30, 25 | -- | -- |
| SRS Capital Advisors, Inc. | 702 | Sep 30, 25 | +689 | -- |
| Smartleaf Asset Management LLC | 398 | Sep 30, 25 | +231 | -- |
| Hurley Capital, LLC | 366 | Sep 30, 25 | -- | -- |
| Advisory Services Network, LLC | 350 | Sep 30, 25 | +350 | -- |
| ADVISOR GROUP HOLDINGS, INC. | 336 | Sep 30, 25 | -11 | -- |
| Optiver Holding B.V. | 310 | Sep 30, 25 | +5 | -- |
| Bell Investment Advisors, Inc | 298 | Sep 30, 25 | -- | -- |
| Clearstead Advisors, LLC | 291 | Sep 30, 25 | -- | -- |
| Daiwa Securities Group Inc. | 204 | Sep 30, 25 | -- | -- |
| Hillsdale Investment Management Inc. | 200 | Sep 30, 25 | -- | -- |
| BESSEMER GROUP INC | 186 | Sep 30, 25 | +76 | -- |
| Root Financial Partners, LLC | 106 | Sep 30, 25 | +106 | -- |
| Triumph Capital Management | 100 | Sep 30, 25 | +100 | -- |
| ROTHSCHILD INVESTMENT LLC | 75 | Sep 30, 25 | -15 | -- |
| Larson Financial Group LLC | 74 | Sep 30, 25 | +74 | -- |
| JPL Wealth Management, LLC | 70 | Sep 30, 25 | +70 | -- |
| Covestor Ltd | 64 | Sep 30, 25 | +64 | -- |
| EverSource Wealth Advisors, LLC | 62 | Sep 30, 25 | -- | -- |
| FEDERATED HERMES, INC. | 53 | Sep 30, 25 | -544 | -- |
| Parkside Financial Bank & Trust | 45 | Sep 30, 25 | -- | -- |
| MAI Capital Management | 25 | Sep 30, 25 | -9 | -- |
| Allworth Financial LP | 17 | Sep 30, 25 | +2 | -- |
| QUADRANT CAPITAL GROUP LLC | 16 | Sep 30, 25 | +16 | -- |
| Parallel Advisors, LLC | 12 | Sep 30, 25 | -- | -- |
| Steward Partners Investment Advisory, LLC | 9 | Sep 30, 25 | -- | -- |
| Wealthspire Advisors, LLC | 6 | Sep 30, 25 | +6 | -- |
| SBI Securities Co., Ltd. | 4 | Sep 30, 25 | +1 | -- |
| HFM Investment Advisors, LLC | 3 | Sep 30, 25 | +2 | -- |
| JONES FINANCIAL COMPANIES LLLP | 1 | Sep 30, 25 | -- | -- |
| Trexquant Investment LP | -- | Sep 30, 25 | -98.40K | -- |
| Headlands Technologies LLC | -- | Sep 30, 25 | -12.64K | -- |
| IEQ CAPITAL, LLC | -- | Sep 30, 25 | -8.09K | -- |
| Caitong International Asset Management Co., Ltd | -- | Sep 30, 25 | -21 | -- |
| Skopos Labs, Inc. | -- | Sep 30, 25 | -1.13K | -- |
| Polar Asset Management Partners Inc. | -- | Sep 30, 25 | -14.70K | -- |
| Casdin Capital, LLC | -- | Sep 30, 25 | -100.00K | -- |
| FRANKLIN RESOURCES INC | -- | Sep 30, 25 | -50.11K | -- |
| RAYMOND JAMES FINANCIAL INC | -- | Sep 30, 25 | -442 | -- |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | -- | Sep 30, 25 | -187.40K | -- |
| CANTOR FITZGERALD, L. P. | -- | Sep 30, 25 | -134.20K | -- |
| CenterBook Partners LP | -- | Sep 30, 25 | -243.06K | -- |
| ORBIMED ADVISORS LLC | -- | Sep 30, 25 | -557.90K | -- |
| Kestra Investment Management, LLC | -- | Sep 30, 25 | -139 | -- |
| Centiva Capital, LP | -- | Sep 30, 25 | -15.04K | -- |
| Schonfeld Strategic Advisors LLC | -- | Sep 30, 25 | -46.35K | -- |
| Qube Research & Technologies Ltd | -- | Sep 30, 25 | -67.38K | -- |
| Granahan Investment Management, LLC | -- | Sep 30, 25 | -41.89K | -- |
| UBS OCONNOR LLC | -- | Sep 30, 25 | -56.81K | -- |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | -- | Sep 30, 25 | -82.68K | -- |
| THRIVENT FINANCIAL FOR LUTHERANS | -- | Sep 30, 25 | -17.53K | -- |
| PANAGORA ASSET MANAGEMENT INC | -- | Sep 30, 25 | -47.19K | -- |
| FOX RUN MANAGEMENT, L.L.C. | -- | Sep 30, 25 | -17.71K | -- |
| Jain Global LLC | -- | Sep 30, 25 | -7.75K | -- |
| CAPITAL FUND MANAGEMENT S.A. | -- | Sep 30, 25 | -68.50K | -- |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | -- | Sep 30, 25 | -68.10K | -- |
| Engineers Gate Manager LP | -- | Sep 30, 25 | -16.55K | -- |
| TWO SIGMA SECURITIES, LLC | -- | Sep 30, 25 | -8.65K | -- |
| LAZARD ASSET MANAGEMENT LLC | -- | Sep 30, 25 | -534 | -- |
| AXA S.A. | -- | Sep 30, 25 | -225.37K | -- |
| CIBC WORLD MARKETS CORP | 6.96K | Jun 30, 25 | -5.58K | -- |
| NORGES BANK | 6.76K | Jun 30, 25 | +6.76K | -- |
| First Horizon Advisors, Inc. | 523 | Jun 30, 25 | -21 | -- |
| E Fund Management Co., Ltd. | -- | Jun 30, 25 | -8.75K | -- |
| Cutter Capital Management, LP | 235.35K | Mar 31, 25 | -66.27K | -- |
| Kodai Capital Management LP | 50.69K | Mar 31, 25 | +50.69K | -- |
| Lindbrook Capital, LLC | 257 | Mar 31, 25 | +94 | -- |
| Nuveen Asset Management, LLC | 157.27K | Dec 31, 24 | -5.47K | -- |
| AlphaCentric Advisors LLC | 6.14K | Dec 31, 24 | +6.14K | -- |
| Cassady Schiller Wealth Management, LLC | 15 | Dec 31, 24 | +15 | -- |
| CAXTON ASSOCIATES LP | -- | Dec 31, 24 | -8.54K | -- |
| SEVEN EIGHT CAPITAL, LP | -- | Sep 30, 24 | -39.26K | -- |
| BlackRock Inc. | 4.86M | Jun 30, 24 | +200.91K | -- |
| Altitude Crest Partners Inc. | 113.10K | Mar 31, 24 | +113.10K | -- |
| CREDIT SUISSE AG/ | 111.63K | Mar 31, 24 | +2.44K | -- |
| Cutler Group LLC / CA | 7.13K | Mar 31, 24 | +130 | -- |
| Point72 Middle East FZE | 27.75K | Dec 31, 23 | +27.75K | -- |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 24.00K | Sep 30, 23 | -- | -- |
| Ergoteles LLC | -- | Sep 30, 23 | -53.13K | -- |
| PICTET ASSET MANAGEMENT SA | 882.40K | Jun 30, 23 | +186.33K | -- |
| ETF MANAGERS GROUP, LLC | 24.80K | Mar 31, 23 | +370 | -- |
| Monarch Partners Asset Management LLC | 58.25K | Dec 31, 22 | +426 | -- |
| EATON VANCE MANAGEMENT | 68.45K | Sep 30, 22 | -6.53K | -- |
| AlphaCrest Capital Management LLC | 26.46K | Sep 30, 22 | -7.91K | -- |
| WIPFLI FINANCIAL ADVISORS LLC, | 228 | Sep 30, 22 | +228 | -- |
| American Portfolios Advisors | 45 | Sep 30, 22 | -- | -- |
| Jefferies Group LLC | -- | Sep 30, 22 | -17.01K | -- |
| PARAMETRIC PORTFOLIO ASSOCIATES LLC | 26.86K | Mar 31, 22 | -22.61K | -- |
| Amalgamated Financial Corp. | 6.56K | Mar 31, 22 | +6.56K | -- |
| PICTET ASSET MANAGEMENT LTD | 106.56K | Jun 30, 21 | -21.85K | -- |
| AMUNDI ASSET MANAGEMENT US, INC. | 6.70K | Mar 31, 21 | -- | -- |
| Aperio Group, LLC | 118.32K | Dec 31, 20 | +66.67K | -- |
| VIRTUS ALTERNATIVE INVESTMENT ADVISERS, INC. | 154 | Dec 31, 20 | -148 | -- |
| ETRADE Capital Management LLC | 12.87K | Sep 30, 20 | +836 | -- |
| SHINE INVESTMENT ADVISORY SERVICES INC | 357 | Sep 30, 20 | -- | -- |
| Polar Capital LLP | -- | Sep 30, 20 | -150.00K | -- |
| NumerixS Investment Technologies Inc | 3.30K | Jun 30, 20 | +3.30K | -- |
| Elk Creek Partners, LLC | 164.77K | Mar 31, 20 | -2.16K | -- |
| Xact Kapitalforvaltning AB | 7.62K | Mar 31, 20 | -- | -- |
| Advisor Group, Inc. | 1.24K | Dec 31, 19 | +1.05K | -- |
| LADENBURG THALMANN FINANCIAL SERVICES INC. | 324 | Dec 31, 19 | +14 | -- |
| TIVERTON ASSET MANAGEMENT LLC | 5.20K | Sep 30, 19 | +3.50K | -- |
| Glen Harbor Capital Management LLC | 1.39K | Sep 30, 19 | +952 | -- |
| Meadow Creek Investment Management LLC | 1.15K | Sep 30, 19 | +784 | -- |
| Elkfork Partners LLC | 902 | Sep 30, 19 | +616 | -- |
| Tyers Asset Management LLC | 656 | Sep 30, 19 | +448 | -- |
| Opus Point Partners Management, LLC | -- | Sep 30, 19 | -4.81K | -- |
| CAPITAL GUARDIAN TRUST CO | 484.76K | Jun 30, 19 | -162.60K | -- |
| BB BIOTECH AG | 2.98M | Mar 31, 19 | +100.00K | -- |
| OppenheimerFunds, Inc. | 330.65K | Mar 31, 19 | +36.46K | -- |
| TIAA CREF INVESTMENT MANAGEMENT LLC | 158.03K | Mar 31, 19 | +9.63K | -- |
| TEACHERS ADVISORS, LLC | 78.33K | Mar 31, 19 | +3.43K | -- |
| FINANCIAL & INVESTMENT MANAGEMENT GROUP LTD | 39.74K | Dec 31, 18 | -5.15K | -- |
| Opera Trading Capital | -- | Dec 31, 18 | -4.85K | -- |
| PEAK6 Group LLC | 4.58K | Jun 30, 18 | +4.58K | -- |
| Global X Management CO LLC | 733 | Jun 30, 18 | +733 | -- |
| COLUMBIA WANGER ASSET MANAGEMENT LLC | 760.12K | Dec 31, 17 | -129.03K | -- |
| AHL Partners LLP | -- | Dec 31, 17 | -6.97K | -- |
| RAY GERALD L & ASSOCIATES LTD | 29.46K | Sep 30, 17 | -3.90K | -- |
| Virtu KCG Holdings LLC | 14.45K | Jun 30, 17 | +14.45K | -- |
| JANUS HENDERSON INVESTORS US LLC | 375.08K | Mar 31, 17 | -9.18K | -- |
| BlackRock Fund Advisors | 917.14K | Dec 31, 16 | +106.90K | -- |
| BlackRock Institutional Trust Company, N.A. | 870.88K | Dec 31, 16 | +172.66K | -- |
| BLACKROCK ADVISORS LLC | 202.52K | Dec 31, 16 | -183.23K | -- |
| BlackRock Group LTD | 104.41K | Dec 31, 16 | -95.15K | -- |
| BlackRock Investment Management, LLC | 25.62K | Dec 31, 16 | -4.31K | -- |
| MSI Financial Services Inc | 15 | Dec 31, 16 | -- | -- |
| Geduld E E | -- | Dec 31, 16 | -15.00K | -- |
| Emerald Acquisition Ltd. | 12.11K | Sep 30, 16 | +4.50K | -- |
| Flagship Ventures 2007 General Partner LLC | 1.93M | Jun 30, 16 | +1.93M | -- |
| Flagship Ventures Fund 2007, L.P. | 1.93M | Mar 31, 16 | +1.93M | -- |
| Apex Capital Management | 250.04K | Mar 31, 16 | +21.17K | -- |
| RUSSELL FRANK CO/ | 1.71K | Mar 31, 16 | -1.81K | -- |
| Bellevue Asset Management AG | 54.00K | Dec 31, 15 | -- | -- |
| J.P. Turner & Co Capital Mnagement, LLC | 5.40K | Sep 30, 15 | +5.40K | -- |
| Index Management Solutions, LLC | 42 | Sep 30, 15 | +42 | -- |
| MANAGED ACCOUNT ADVISORS LLC | 49.64K | Jun 30, 15 | +1.48K | -- |
| BAIRD ROBERT W & CO INC /WI/ | -- | Mar 31, 15 | -3.17K | -- |
| COLUMBIA CAPITAL LLC | 5.27K | Dec 31, 14 | +5.27K | -- |
| UBS AG | 25.88K | Sep 30, 14 | +23.97K | -- |
| Stifel Trust Company, N.A. | 100 | Sep 30, 14 | -- | -- |
| Jane Street Holding, LLC | -- | Dec 31, 13 | -21.98K | -- |