Amylyx Pharmaceuticals, Inc.AMLXNASDAQ
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| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| SALEM INVESTMENT COUNSELORS INC | -- | Dec 31, 25 | -55 | -- |
| JENNISON ASSOCIATES LLC | -- | Dec 31, 25 | -578.66K | -- |
| Hennion & Walsh Asset Management, Inc. | -- | Dec 31, 25 | -47.90K | -- |
| FMR LLC | 11.38M | Sep 30, 25 | +8.33M | -- |
| PERCEPTIVE ADVISORS LLC | 8.95M | Sep 30, 25 | +1.05M | -- |
| BlackRock, Inc. | 7.14M | Sep 30, 25 | +1.63M | -- |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 6.82M | Sep 30, 25 | -1.98M | -- |
| TCG Crossover Management, LLC | 6.24M | Sep 30, 25 | +300.00K | -- |
| Saturn V Capital Management LLC | 4.60M | Sep 30, 25 | +1.34M | -- |
| COMMODORE CAPITAL LP | 4.08M | Sep 30, 25 | +4.08M | -- |
| First Light Asset Management, LLC | 3.36M | Sep 30, 25 | +3.36M | -- |
| Point72 Asset Management, L.P. | 2.79M | Sep 30, 25 | -1.75M | -- |
| JANUS HENDERSON GROUP PLC | 2.54M | Sep 30, 25 | +2.54M | -- |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 2.42M | Sep 30, 25 | +1.16M | -- |
| Almitas Capital LLC | 2.12M | Sep 30, 25 | -- | -- |
| GOLDMAN SACHS GROUP INC | 2.01M | Sep 30, 25 | +712.65K | -- |
| MORGAN STANLEY | 1.95M | Sep 30, 25 | +1.46M | -- |
| Paradigm Biocapital Advisors LP | 1.90M | Sep 30, 25 | +1.90M | -- |
| GEODE CAPITAL MANAGEMENT, LLC | 1.81M | Sep 30, 25 | +119.63K | -- |
| 683 Capital Management, LLC | 1.76M | Sep 30, 25 | -400.00K | -- |
| GREAT POINT PARTNERS LLC | 1.70M | Sep 30, 25 | -300.00K | -- |
| STATE STREET CORP | 1.62M | Sep 30, 25 | +612.35K | -- |
| EVENTIDE ASSET MANAGEMENT, LLC | 1.51M | Sep 30, 25 | +1.51M | -- |
| BALYASNY ASSET MANAGEMENT L.P. | 1.48M | Sep 30, 25 | +1.48M | -- |
| Logos Global Management LP | 1.45M | Sep 30, 25 | +1.45M | -- |
| DEUTSCHE BANK AG\ | 1.37M | Sep 30, 25 | +748.60K | -- |
| T. Rowe Price Investment Management, Inc. | 1.20M | Sep 30, 25 | +1.20M | -- |
| Connor, Clark & Lunn Investment Management Ltd. | 1.11M | Sep 30, 25 | -47.48K | -- |
| Nantahala Capital Management, LLC | 935.68K | Sep 30, 25 | -2.00M | -- |
| Boxer Capital Management, LLC | 900.00K | Sep 30, 25 | -325.00K | -- |
| ADAR1 Capital Management, LLC | 866.20K | Sep 30, 25 | -338.90K | -- |
| Woodline Partners LP | 845.29K | Sep 30, 25 | -355.00K | -- |
| NORTHERN TRUST CORP | 822.24K | Sep 30, 25 | +2.07K | -- |
| Invesco Ltd. | 810.64K | Sep 30, 25 | +223.76K | -- |
| ORBIMED ADVISORS LLC | 750.60K | Sep 30, 25 | +437.40K | -- |
| SILVERARC CAPITAL MANAGEMENT, LLC | 700.00K | Sep 30, 25 | +700.00K | -- |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 645.18K | Sep 30, 25 | +56.77K | -- |
| BRAIDWELL LP | 612.84K | Sep 30, 25 | +612.84K | -- |
| Parkman Healthcare Partners LLC | 579.17K | Sep 30, 25 | -70.83K | -- |
| DIMENSIONAL FUND ADVISORS LP | 509.78K | Sep 30, 25 | +136.04K | -- |
| Cormorant Asset Management, LP | 500.00K | Sep 30, 25 | +500.00K | -- |
| Rock Springs Capital Management LP | 499.76K | Sep 30, 25 | -- | -- |
| Ally Bridge Group (NY) LLC | 437.39K | Sep 30, 25 | +437.39K | -- |
| PFM Health Sciences, LP | 436.16K | Sep 30, 25 | -296.10K | -- |
| BANK OF AMERICA CORP /DE/ | 429.52K | Sep 30, 25 | -22.29K | -- |
| MILLENNIUM MANAGEMENT LLC | 417.77K | Sep 30, 25 | -1.09M | -- |
| BARCLAYS PLC | 414.11K | Sep 30, 25 | +283.84K | -- |
| ACADIAN ASSET MANAGEMENT LLC | 367.33K | Sep 30, 25 | -201.75K | -- |
| ACUTA CAPITAL PARTNERS, LLC | 333.26K | Sep 30, 25 | +333.26K | -- |
| Alpha Wave Global, LP | 327.31K | Sep 30, 25 | +51.47K | -- |
| Patient Square Capital LP | 316.31K | Sep 30, 25 | +316.31K | -- |
| StemPoint Capital LP | 276.88K | Sep 30, 25 | +276.88K | -- |
| TFG Asset Management GP Ltd | 258.24K | Sep 30, 25 | +39.49K | -- |
| WELLINGTON MANAGEMENT GROUP LLP | 236.20K | Sep 30, 25 | -52.42K | -- |
| CITADEL ADVISORS LLC | 234.67K | Sep 30, 25 | -1.01M | -- |
| Trexquant Investment LP | 222.88K | Sep 30, 25 | +222.88K | -- |
| FEDERATED HERMES, INC. | 212.38K | Sep 30, 25 | +8.45K | -- |
| Aldebaran Capital, LLC | 204.47K | Sep 30, 25 | -13.35K | -- |
| Longaeva Partners L.P. | 200.00K | Sep 30, 25 | +200.00K | -- |
| Bank of New York Mellon Corp | 182.96K | Sep 30, 25 | +32.12K | -- |
| SummitTX Capital, L.P. | 168.00K | Sep 30, 25 | +168.00K | -- |
| Qube Research & Technologies Ltd | 167.11K | Sep 30, 25 | -270.92K | -- |
| FRED ALGER MANAGEMENT, LLC | 164.04K | Sep 30, 25 | +164.04K | -- |
| Nuveen, LLC | 160.42K | Sep 30, 25 | +4.88K | -- |
| BANK OF MONTREAL /CAN/ | 143.75K | Sep 30, 25 | +240 | -- |
| TWO SIGMA ADVISERS, LP | 143.00K | Sep 30, 25 | -327.00K | -- |
| AMERIPRISE FINANCIAL INC | 133.51K | Sep 30, 25 | +38.29K | -- |
| Kennondale Capital Management LLC | 108.61K | Sep 30, 25 | +13.45K | -- |
| PRICE T ROWE ASSOCIATES INC /MD/ | 100.44K | Sep 30, 25 | +9.05K | -- |
| TANG CAPITAL MANAGEMENT LLC | 100.00K | Sep 30, 25 | -- | -- |
| DIADEMA PARTNERS LP | 100.00K | Sep 30, 25 | +100.00K | -- |
| RHUMBLINE ADVISERS | 98.66K | Sep 30, 25 | -1.92K | -- |
| TWO SIGMA INVESTMENTS, LP | 98.42K | Sep 30, 25 | -460.43K | -- |
| WELLS FARGO & COMPANY/MN | 93.69K | Sep 30, 25 | +55.59K | -- |
| ROYAL BANK OF CANADA | 93.01K | Sep 30, 25 | +80.88K | -- |
| DARK FOREST CAPITAL MANAGEMENT LP | 86.80K | Sep 30, 25 | +86.80K | -- |
| EAM Investors, LLC | 75.11K | Sep 30, 25 | -24.85K | -- |
| AQR CAPITAL MANAGEMENT LLC | 73.64K | Sep 30, 25 | +73.64K | -- |
| ALLIANCEBERNSTEIN L.P. | 71.50K | Sep 30, 25 | +40.90K | -- |
| Maven Securities LTD | 70.00K | Sep 30, 25 | +70.00K | -- |
| D. E. Shaw & Co., Inc. | 68.88K | Sep 30, 25 | -82.63K | -- |
| Legal & General Group Plc | 67.21K | Sep 30, 25 | +59.81K | -- |
| Numerai GP LLC | 67.15K | Sep 30, 25 | +67.15K | -- |
| Verition Fund Management LLC | 63.90K | Sep 30, 25 | +63.90K | -- |
| READYSTATE ASSET MANAGEMENT LP | 59.13K | Sep 30, 25 | +59.13K | -- |
| Brevan Howard Capital Management LP | 56.67K | Sep 30, 25 | +56.67K | -- |
| Russell Investments Group, Ltd. | 55.41K | Sep 30, 25 | +49.18K | -- |
| GSA CAPITAL PARTNERS LLP | 52.11K | Sep 30, 25 | -118.43K | -- |
| Mariner, LLC | 48.03K | Sep 30, 25 | -641 | -- |
| Schonfeld Strategic Advisors LLC | 43.64K | Sep 30, 25 | -602.81K | -- |
| MetLife Investment Management, LLC | 42.93K | Sep 30, 25 | -- | -- |
| TD ASSET MANAGEMENT INC | 40.97K | Sep 30, 25 | +40.97K | -- |
| CITIGROUP INC | 38.08K | Sep 30, 25 | +6.99K | -- |
| JPMORGAN CHASE & CO | 35.84K | Sep 30, 25 | -52.15K | -- |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 32.00K | Sep 30, 25 | -5.99K | -- |
| Monashee Investment Management LLC | 30.00K | Sep 30, 25 | +30.00K | -- |
| Quadrature Capital Ltd | 28.29K | Sep 30, 25 | -1.14K | -- |
| GUGGENHEIM CAPITAL LLC | 24.90K | Sep 30, 25 | -10.85K | -- |
| Campbell & CO Investment Adviser LLC | 24.48K | Sep 30, 25 | +24.48K | -- |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 23.79K | Sep 30, 25 | -2.21K | -- |
| Persistent Asset Partners Ltd | 22.91K | Sep 30, 25 | +22.91K | -- |
| NEW YORK STATE COMMON RETIREMENT FUND | 21.90K | Sep 30, 25 | -- | -- |
| Vanguard Personalized Indexing Management, LLC | 21.10K | Sep 30, 25 | -22 | -- |
| BROWN ADVISORY INC | 19.93K | Sep 30, 25 | -- | -- |
| RENAISSANCE TECHNOLOGIES LLC | 19.90K | Sep 30, 25 | -376.30K | -- |
| INTECH INVESTMENT MANAGEMENT LLC | 19.49K | Sep 30, 25 | -16.82K | -- |
| HSBC HOLDINGS PLC | 19.37K | Sep 30, 25 | +19.37K | -- |
| Police & Firemen's Retirement System of New Jersey | 19.26K | Sep 30, 25 | +3.27K | -- |
| OXFORD ASSET MANAGEMENT LLP | 19.12K | Sep 30, 25 | +19.12K | -- |
| EntryPoint Capital, LLC | 17.17K | Sep 30, 25 | +17.17K | -- |
| Quantbot Technologies LP | 16.65K | Sep 30, 25 | +16.65K | -- |
| ProShare Advisors LLC | 15.04K | Sep 30, 25 | -2.51K | -- |
| BNP PARIBAS ARBITRAGE, SNC | 14.61K | Sep 30, 25 | +7.34K | -- |
| STATE OF WISCONSIN INVESTMENT BOARD | 13.88K | Sep 30, 25 | +13.88K | -- |
| Quest Partners LLC | 13.64K | Sep 30, 25 | +13.64K | -- |
| PROFUND ADVISORS LLC | 13.42K | Sep 30, 25 | +13.42K | -- |
| VOYA INVESTMENT MANAGEMENT LLC | 12.99K | Sep 30, 25 | -6.49K | -- |
| CAPSTONE INVESTMENT ADVISORS, LLC | 10.63K | Sep 30, 25 | +10.63K | -- |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 10.40K | Sep 30, 25 | +10.40K | -- |
| PRUDENTIAL FINANCIAL INC | 10.15K | Sep 30, 25 | -5.46K | -- |
| Valeo Financial Advisors, LLC | 10.00K | Sep 30, 25 | -- | -- |
| Tower Research Capital LLC (TRC) | 6.59K | Sep 30, 25 | -877 | -- |
| Point72 (DIFC) Ltd | 5.97K | Sep 30, 25 | +5.97K | -- |
| Ameritas Investment Partners, Inc. | 5.79K | Sep 30, 25 | -1.29K | -- |
| Cubist Systematic Strategies, LLC | 5.60K | Sep 30, 25 | -117.64K | -- |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 4.33K | Sep 30, 25 | +3 | -- |
| Aster Capital Management (DIFC) Ltd | 3.57K | Sep 30, 25 | +3.57K | -- |
| AMALGAMATED BANK | 2.37K | Sep 30, 25 | -- | -- |
| SRS Capital Advisors, Inc. | 2.24K | Sep 30, 25 | +2.24K | -- |
| Steward Partners Investment Advisory, LLC | 1.50K | Sep 30, 25 | -500 | -- |
| SBI Securities Co., Ltd. | 1.25K | Sep 30, 25 | +1.25K | -- |
| Sterling Capital Management LLC | 1.21K | Sep 30, 25 | +657 | -- |
| CLEAR STREET MARKETS LLC | 1.19K | Sep 30, 25 | +1.19K | -- |
| Global Retirement Partners, LLC | 1.00K | Sep 30, 25 | -1.50K | -- |
| North Capital, Inc. | 501 | Sep 30, 25 | +1 | -- |
| PNC FINANCIAL SERVICES GROUP, INC. | 485 | Sep 30, 25 | +432 | -- |
| Caitong International Asset Management Co., Ltd | 366 | Sep 30, 25 | -2.55K | -- |
| Daiwa Securities Group Inc. | 266 | Sep 30, 25 | -- | -- |
| ADVISOR GROUP HOLDINGS, INC. | 225 | Sep 30, 25 | -15 | -- |
| EVOLUTION WEALTH MANAGEMENT INC. | 165 | Sep 30, 25 | +165 | -- |
| HARBOUR INVESTMENTS, INC. | 90 | Sep 30, 25 | -- | -- |
| Rise Advisors, LLC | 64 | Sep 30, 25 | +64 | -- |
| JONES FINANCIAL COMPANIES LLLP | 30 | Sep 30, 25 | +30 | -- |
| EverSource Wealth Advisors, LLC | 25 | Sep 30, 25 | -- | -- |
| Allworth Financial LP | 12 | Sep 30, 25 | +12 | -- |
| Rockefeller Capital Management L.P. | 5 | Sep 30, 25 | +5 | -- |
| IFP Advisors, Inc | 1 | Sep 30, 25 | +1 | -- |
| J. Goldman & Co LP | -- | Sep 30, 25 | -258.60K | -- |
| TUDOR INVESTMENT CORP ET AL | -- | Sep 30, 25 | -12.07K | -- |
| Graham Capital Management, L.P. | -- | Sep 30, 25 | -34.15K | -- |
| JANE STREET GROUP, LLC | -- | Sep 30, 25 | -186.99K | -- |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | -- | Sep 30, 25 | -110.85K | -- |
| Marex Group plc | -- | Sep 30, 25 | -20.00K | -- |
| Squarepoint Ops LLC | -- | Sep 30, 25 | -40.64K | -- |
| GROUP ONE TRADING, L.P. | -- | Sep 30, 25 | -25.86K | -- |
| Centiva Capital, LP | -- | Sep 30, 25 | -45.46K | -- |
| LOS ANGELES CAPITAL MANAGEMENT LLC | -- | Sep 30, 25 | -23.32K | -- |
| Y-Intercept (Hong Kong) Ltd | -- | Sep 30, 25 | -240.38K | -- |
| CANTOR FITZGERALD, L. P. | -- | Sep 30, 25 | -50.00K | -- |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | -- | Sep 30, 25 | -25.70K | -- |
| RAYMOND JAMES FINANCIAL INC | -- | Sep 30, 25 | -104 | -- |
| Jump Financial, LLC | -- | Sep 30, 25 | -47.80K | -- |
| AMERICAN CENTURY COMPANIES INC | -- | Sep 30, 25 | -134.38K | -- |
| Skopos Labs, Inc. | -- | Sep 30, 25 | -42 | -- |
| Allostery Investments LP | 120.12K | Jun 30, 25 | -145.98K | -- |
| Ghost Tree Capital, LLC | 325.00K | Sep 30, 24 | +325.00K | -- |
| nVerses Capital, LLC | 2.10K | Sep 30, 24 | +2.10K | -- |
| Boxer Capital, LLC | -- | Sep 30, 24 | -1.50M | -- |
| BlackRock Inc. | 2.67M | Jun 30, 24 | -1.80M | -- |
| CREDIT SUISSE AG/ | 36.64K | Mar 31, 24 | -1.41K | -- |
| Cipher Capital LP | 10.72K | Mar 31, 24 | +10.72K | -- |
| Cutler Group LLC / CA | 1.00K | Mar 31, 24 | +100 | -- |
| Point72 Middle East FZE | 9.14K | Dec 31, 23 | -14.23K | -- |
| Weiss Multi-Strategy Advisers LLC | -- | Dec 31, 23 | -14.05K | -- |
| PUTNAM INVESTMENTS LLC | -- | Dec 31, 23 | -46.46K | -- |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 295.00K | Sep 30, 23 | +270.00K | -- |
| PICTET ASSET MANAGEMENT SA | 601.65K | Jun 30, 23 | -832.20K | -- |
| Tekla Capital Management LLC | 104.01K | Jun 30, 23 | +104.01K | -- |
| Kula Investments, LLC | 12.51K | Mar 31, 23 | +12.51K | -- |
| Jefferies Group LLC | 2.79K | Sep 30, 22 | +2.79K | -- |
| Amalgamated Financial Corp. | 1.76K | Mar 31, 22 | +1.76K | -- |