Amylyx Pharmaceuticals, Inc.(AMLX)

$13.29▼-0.59 (-4.29%)

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Amylyx Pharmaceuticals, Inc.(AMLX)

NASDAQ

$13.29▼-0.59 (-4.29%)

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AMLX(AMLX)

AMLX

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Institutional Ownership

Top 289 Institutional Holders

Holder	Shares	Date	Change	% Held
FMR LLC	16.63M	Mar 31, 26	+112.12K	20.01%
BlackRock, Inc.	8.83M	Mar 31, 26	-225.59K	10.62%
PERCEPTIVE ADVISORS LLC	8.28M	Mar 31, 26	--	9.97%
TCG Crossover Management, LLC	6.24M	Mar 31, 26	--	7.51%
COMMODORE CAPITAL LP	5.65M	Mar 31, 26	--	6.80%
JANUS HENDERSON GROUP PLC	4.99M	Mar 31, 26	+520.20K	6.00%
Saturn V Capital Management LLC	4.35M	Mar 31, 26	-146.60K	5.23%
ADAGE CAPITAL PARTNERS GP, L.L.C.	3.56M	Mar 31, 26	+783.71K	4.28%
First Light Asset Management, LLC	3.19M	Mar 31, 26	-164.89K	3.84%
DRIEHAUS CAPITAL MANAGEMENT LLC	2.99M	Mar 31, 26	-122.36K	3.59%
GOLDMAN SACHS GROUP INC	2.63M	Mar 31, 26	+12.77K	3.16%
STATE STREET CORP	2.36M	Mar 31, 26	+293.28K	2.84%
FRANKLIN RESOURCES INC	2.26M	Mar 31, 26	+1.06M	2.72%
GEODE CAPITAL MANAGEMENT, LLC	2.21M	Mar 31, 26	+45.40K	2.66%
MORGAN STANLEY	2.18M	Mar 31, 26	-184.28K	2.62%
Almitas Capital LLC	2.12M	Mar 31, 26	--	2.55%
GREAT POINT PARTNERS LLC	1.75M	Mar 31, 26	--	2.11%
683 Capital Management, LLC	1.53M	Mar 31, 26	-120.00K	1.84%
EVENTIDE ASSET MANAGEMENT, LLC	1.51M	Mar 31, 26	+810	1.82%
DEUTSCHE BANK AG\	1.27M	Mar 31, 26	-65.45K	1.53%
Siren, L.L.C.	1.23M	Mar 31, 26	+1.23M	1.48%
BALYASNY ASSET MANAGEMENT L.P.	1.11M	Mar 31, 26	+248.59K	1.33%
BARCLAYS PLC	971.85K	Mar 31, 26	+676.68K	1.17%
DIMENSIONAL FUND ADVISORS LP	903.19K	Mar 31, 26	+131.94K	1.09%
Connor, Clark & Lunn Investment Management Ltd.	868.33K	Mar 31, 26	-135.70K	1.04%
Woodline Partners LP	845.80K	Mar 31, 26	+392	1.02%
Boxer Capital Management, LLC	800.00K	Mar 31, 26	--	0.96%
NORTHERN TRUST CORP	779.91K	Mar 31, 26	-157.86K	0.94%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	716.23K	Mar 31, 26	+3.23K	0.86%
Qube Research & Technologies Ltd	702.24K	Mar 31, 26	+289.36K	0.84%
Logos Global Management LP	700.00K	Mar 31, 26	-250.00K	0.84%
StemPoint Capital LP	669.68K	Mar 31, 26	+104.55K	0.81%
Parkman Healthcare Partners LLC	621.46K	Mar 31, 26	+239.70K	0.75%
JUPITER ASSET MANAGEMENT LTD	592.65K	Mar 31, 26	+577.08K	0.71%
VANGUARD FIDUCIARY TRUST CO	586.15K	Mar 31, 26	+586.15K	0.71%
Nantahala Capital Management, LLC	535.68K	Mar 31, 26	-300.00K	0.64%
Rock Springs Capital Management LP	499.76K	Mar 31, 26	--	0.60%
CITADEL ADVISORS LLC	411.53K	Mar 31, 26	+66.56K	0.50%
FEDERATED HERMES, INC.	363.55K	Mar 31, 26	-93.87K	0.44%
HighVista Strategies LLC	352.08K	Mar 31, 26	+113.27K	0.42%
Cormorant Asset Management, LP	350.00K	Mar 31, 26	-50.00K	0.42%
UBS Group AG	324.32K	Mar 31, 26	-219.00K	0.39%
TFG Asset Management GP Ltd	317.88K	Mar 31, 26	+45.05K	0.38%
iA Global Asset Management Inc.	304.79K	Mar 31, 26	+304.79K	0.37%
Nuveen, LLC	264.90K	Mar 31, 26	-19.05K	0.32%
Bank of New York Mellon Corp	251.10K	Mar 31, 26	+33.76K	0.30%
WELLINGTON MANAGEMENT GROUP LLP	241.55K	Mar 31, 26	+15.77K	0.29%
SummitTX Capital, L.P.	227.01K	Mar 31, 26	+8.61K	0.27%
Aldebaran Capital, LLC	197.89K	Mar 31, 26	-616	0.24%
Invesco Ltd.	171.62K	Mar 31, 26	-4.29K	0.21%
TWO SIGMA INVESTMENTS, LP	161.94K	Mar 31, 26	-182.46K	0.19%
JPMORGAN CHASE & CO	159.66K	Mar 31, 26	+93.12K	0.19%
UBS ASSET MANAGEMENT AMERICAS INC	157.09K	Mar 31, 26	+58.25K	0.19%
ACUTA CAPITAL PARTNERS, LLC	151.07K	Mar 31, 26	-182.19K	0.18%
PFM Health Sciences, LP	145.28K	Mar 31, 26	+10.73K	0.17%
Alpha Wave Global, LP	142.34K	Mar 31, 26	-175.34K	0.17%
Swiss National Bank	130.30K	Mar 31, 26	-31.40K	0.16%
PRICE T ROWE ASSOCIATES INC /MD/	121.44K	Mar 31, 26	+13.89K	0.15%
Squarepoint Ops LLC	114.88K	Mar 31, 26	+38.31K	0.14%
RHUMBLINE ADVISERS	108.47K	Mar 31, 26	+9.19K	0.13%
Point72 Asset Management, L.P.	106.53K	Mar 31, 26	-228.47K	0.13%
ALPS ADVISORS INC	89.98K	Mar 31, 26	-189	0.11%
SEI INVESTMENTS CO	85.28K	Mar 31, 26	+32.42K	0.10%
ALLIANCEBERNSTEIN L.P.	80.80K	Mar 31, 26	+9.30K	0.10%
Schonfeld Strategic Advisors LLC	77.79K	Mar 31, 26	+56.74K	0.09%
WELLS FARGO & COMPANY/MN	75.08K	Mar 31, 26	-71.23K	0.09%
D. E. Shaw & Co., Inc.	74.23K	Mar 31, 26	+1.01K	0.09%
STATE OF WISCONSIN INVESTMENT BOARD	72.06K	Mar 31, 26	-12.08K	0.09%
Walleye Capital LLC	61.71K	Mar 31, 26	+55.97K	0.07%
Russell Investments Group, Ltd.	59.35K	Mar 31, 26	-6.09K	0.07%
Legal & General Group Plc	55.77K	Mar 31, 26	-16.84K	0.07%
Campbell & CO Investment Adviser LLC	54.42K	Mar 31, 26	-24.34K	0.07%
EAM Investors, LLC	53.26K	Mar 31, 26	--	0.06%
MetLife Investment Management, LLC	51.59K	Mar 31, 26	+1.93K	0.06%
Maven Securities LTD	50.00K	Mar 31, 26	+50.00K	0.06%
Numerai GP LLC	48.55K	Mar 31, 26	-64.09K	0.06%
Vanguard Global Advisers, LLC	47.85K	Mar 31, 26	+47.85K	0.06%
VANGUARD ASSET MANAGEMENT, Ltd	43.28K	Mar 31, 26	+43.28K	0.05%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	42.55K	Mar 31, 26	+1.39K	0.05%
Zurcher Kantonalbank (Zurich Cantonalbank)	40.79K	Mar 31, 26	+4.91K	0.05%
SUSQUEHANNA INTERNATIONAL GROUP, LLP	39.80K	Mar 31, 26	-29.09K	0.05%
MANUFACTURERS LIFE INSURANCE COMPANY, THE	38.78K	Mar 31, 26	+11.79K	0.05%
Optimize Financial Inc	32.00K	Mar 31, 26	+32.00K	0.04%
CITIGROUP INC	31.78K	Mar 31, 26	-6.25K	0.04%
TUDOR INVESTMENT CORP ET AL	31.33K	Mar 31, 26	+8.93K	0.04%
AQR CAPITAL MANAGEMENT LLC	29.09K	Mar 31, 26	+1.24K	0.03%
Integrated Quantitative Investments LLC	27.23K	Mar 31, 26	--	0.03%
GUGGENHEIM CAPITAL LLC	25.51K	Mar 31, 26	+270	0.03%
INTECH INVESTMENT MANAGEMENT LLC	24.92K	Mar 31, 26	-7.08K	0.03%
Vanguard Personalized Indexing Management, LLC	24.07K	Mar 31, 26	+3.23K	0.03%
Police & Firemen's Retirement System of New Jersey	23.75K	Mar 31, 26	--	0.03%
State of New Jersey Common Pension Fund D	22.52K	Mar 31, 26	+22.52K	0.03%
NEW YORK STATE COMMON RETIREMENT FUND	21.90K	Mar 31, 26	--	0.03%
PARSONS CAPITAL MANAGEMENT INC/RI	21.64K	Mar 31, 26	--	0.03%
BNP PARIBAS ARBITRAGE, SNC	21.14K	Mar 31, 26	-4.06K	0.03%
Virtus Investment Advisers, Inc.	20.82K	Mar 31, 26	+508	0.03%
Premier Path Wealth Partners, LLC	20.27K	Mar 31, 26	--	0.02%
BROWN ADVISORY INC	19.93K	Mar 31, 26	--	0.02%
Headlands Technologies LLC	19.81K	Mar 31, 26	-10.73K	0.02%
China Universal Asset Management Co., Ltd.	19.49K	Mar 31, 26	+1.59K	0.02%
ProShare Advisors LLC	18.15K	Mar 31, 26	-2.91K	0.02%
Arizona State Retirement System	18.10K	Mar 31, 26	-4.82K	0.02%
Creative Planning	17.88K	Mar 31, 26	+17.88K	0.02%
Vanguard Investments Australia, Ltd.	17.71K	Mar 31, 26	+17.71K	0.02%
KLP KAPITALFORVALTNING AS	17.40K	Mar 31, 26	--	0.02%
PROFUND ADVISORS LLC	17.15K	Mar 31, 26	-3.44K	0.02%
VOYA INVESTMENT MANAGEMENT LLC	15.23K	Mar 31, 26	-20	0.02%
PRUDENTIAL FINANCIAL INC	14.12K	Mar 31, 26	+14.12K	0.02%
Verition Fund Management LLC	13.26K	Mar 31, 26	-16.22K	0.02%
ROYAL BANK OF CANADA	12.38K	Mar 31, 26	-3.26K	0.01%
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.	12.23K	Mar 31, 26	--	0.01%
HSBC HOLDINGS PLC	11.41K	Mar 31, 26	+11.41K	0.01%
Pictet Asset Management Holding SA	10.77K	Mar 31, 26	+10.77K	0.01%
VICTORY CAPITAL MANAGEMENT INC	10.64K	Mar 31, 26	+92	0.01%
GREAT LAKES ADVISORS, LLC	10.38K	Mar 31, 26	+10.38K	0.01%
Valeo Financial Advisors, LLC	10.00K	Mar 31, 26	-5.00K	0.01%
MAI Capital Management	9.01K	Mar 31, 26	+9.01K	0.01%
ACT CAPITAL MANAGEMENT, LLC	9.00K	Mar 31, 26	--	0.01%
Tower Research Capital LLC (TRC)	7.91K	Mar 31, 26	-182	0.01%
Ameritas Investment Partners, Inc.	7.20K	Mar 31, 26	--	0.01%
Mirae Asset Global Investments Co., Ltd.	5.73K	Mar 31, 26	+391	0.01%
STRS OHIO	3.40K	Mar 31, 26	--	0.00%
GF FUND MANAGEMENT CO. LTD.	2.46K	Mar 31, 26	+297	0.00%
US BANCORP \DE\	2.06K	Mar 31, 26	+63	0.00%
State of Wyoming	1.88K	Mar 31, 26	+502	0.00%
KBC Group NV	1.86K	Mar 31, 26	+1.86K	0.00%
LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA	1.80K	Mar 31, 26	--	0.00%
SRS Capital Advisors, Inc.	1.49K	Mar 31, 26	-1.06K	0.00%
BNP Paribas Asset Management Holding S.A.	1.42K	Mar 31, 26	+103	0.00%
Rockefeller Capital Management L.P.	1.27K	Mar 31, 26	+1.01K	0.00%
CWM, LLC	1.26K	Mar 31, 26	+70	0.00%
Sterling Capital Management LLC	1.14K	Mar 31, 26	-490	0.00%
Steward Partners Investment Advisory, LLC	1.00K	Mar 31, 26	-500	0.00%
NISA INVESTMENT ADVISORS, LLC	922	Mar 31, 26	--	0.00%
Westfuller Advisors, LLC	819	Mar 31, 26	--	0.00%
FIFTH THIRD BANCORP	755	Mar 31, 26	+755	0.00%
MEEDER ASSET MANAGEMENT INC	661	Mar 31, 26	-1.44K	0.00%
Dunhill Financial, LLC	600	Mar 31, 26	--	0.00%
ADVISOR GROUP HOLDINGS, INC.	528	Mar 31, 26	+279	0.00%
GAMMA Investing LLC	417	Mar 31, 26	+150	0.00%
J.Safra Asset Management Corp	377	Mar 31, 26	+254	0.00%
LOS ANGELES CAPITAL MANAGEMENT LLC	325	Mar 31, 26	-527	0.00%
EverSource Wealth Advisors, LLC	285	Mar 31, 26	+260	0.00%
PNC FINANCIAL SERVICES GROUP, INC.	283	Mar 31, 26	-155	0.00%
MASSMUTUAL TRUST CO FSB/ADV	282	Mar 31, 26	+129	0.00%
Physician Wealth Advisors, Inc.	274	Mar 31, 26	--	0.00%
JONES FINANCIAL COMPANIES LLLP	270	Mar 31, 26	+240	0.00%
SIGNATUREFD, LLC	254	Mar 31, 26	+254	0.00%
Larson Financial Group LLC	201	Mar 31, 26	+160	0.00%
EASTERN BANK	200	Mar 31, 26	+200	0.00%
HARBOUR INVESTMENTS, INC.	90	Mar 31, 26	--	0.00%
Stone House Investment Management, LLC	73	Mar 31, 26	+73	0.00%
ROTHSCHILD INVESTMENT LLC	55	Mar 31, 26	+55	0.00%
SALEM INVESTMENT COUNSELORS INC	55	Mar 31, 26	+55	0.00%
Allworth Financial LP	40	Mar 31, 26	+28	0.00%
Caitong International Asset Management Co., Ltd	36	Mar 31, 26	-3.82K	0.00%
Farther Finance Advisors, LLC	22	Mar 31, 26	+2	0.00%
Ameritas Advisory Services, LLC	3	Mar 31, 26	+3	0.00%
SBI Securities Co., Ltd.	1	Mar 31, 26	--	0.00%
EVOLUTION WEALTH MANAGEMENT INC.	--	Mar 31, 26	-165	--
FINANCIAL CONSULATE, INC	--	Mar 31, 26	-25	--
VOLORIDGE INVESTMENT MANAGEMENT, LLC	--	Mar 31, 26	-153.36K	--
Rafferty Asset Management, LLC	--	Mar 31, 26	-17.67K	--
Persistent Asset Partners Ltd	--	Mar 31, 26	-31.15K	--
Daiwa Securities Group Inc.	--	Mar 31, 26	-266	--
AMALGAMATED BANK	--	Mar 31, 26	-2.79K	--
Walleye Trading LLC	--	Mar 31, 26	-2.83K	--
BANK OF MONTREAL /CAN/	--	Mar 31, 26	-138.53K	--
Sofinnova Investments, Inc.	--	Mar 31, 26	-527.10K	--
Kennondale Capital Management LLC	--	Mar 31, 26	-53.42K	--
MILLENNIUM MANAGEMENT LLC	--	Mar 31, 26	-46.45K	--
Mariner, LLC	--	Mar 31, 26	-46.34K	--
Atom Investors LP	--	Mar 31, 26	-139.42K	--
AMERIPRISE FINANCIAL INC	--	Mar 31, 26	-502.37K	--
TEACHER RETIREMENT SYSTEM OF TEXAS	--	Mar 31, 26	-12.17K	--
Engineers Gate Manager LP	--	Mar 31, 26	-18.36K	--
ACADIAN ASSET MANAGEMENT LLC	--	Mar 31, 26	-254.33K	--
GSA CAPITAL PARTNERS LLP	--	Mar 31, 26	-36.76K	--
SILVERARC CAPITAL MANAGEMENT, LLC	--	Mar 31, 26	-506.24K	--
Patient Square Capital LP	--	Mar 31, 26	-350.00K	--
FOX RUN MANAGEMENT, L.L.C.	--	Mar 31, 26	-35.41K	--
EntryPoint Capital, LLC	--	Mar 31, 26	-10.49K	--
RENAISSANCE TECHNOLOGIES LLC	--	Mar 31, 26	-192.50K	--
Quadrature Capital Ltd	--	Mar 31, 26	-15.46K	--
SG Americas Securities, LLC	--	Mar 31, 26	-20.85K	--
IFP Advisors, Inc	--	Mar 31, 26	-1	--
SIMPLEX TRADING, LLC	--	Mar 31, 26	-3.73K	--
JANE STREET GROUP, LLC	--	Mar 31, 26	-263.24K	--
Aquatic Capital Management LLC	--	Mar 31, 26	-24.35K	--
T. Rowe Price Investment Management, Inc.	--	Mar 31, 26	-4.52K	--
XTX Topco Ltd	--	Mar 31, 26	-189.67K	--
Trexquant Investment LP	--	Mar 31, 26	-48.11K	--
FMR LLC	16.52M	Dec 31, 25	+5.14M	19.87%
PERCEPTIVE ADVISORS LLC	8.28M	Dec 31, 25	-667.48K	9.97%
TCG Crossover Management, LLC	6.24M	Dec 31, 25	--	7.51%
VANGUARD GROUP INC	5.80M	Dec 31, 25	+531.16K	6.98%
COMMODORE CAPITAL LP	5.65M	Dec 31, 25	+1.57M	6.80%
JANUS HENDERSON GROUP PLC	4.47M	Dec 31, 25	+1.93M	5.37%
First Light Asset Management, LLC	3.36M	Dec 31, 25	-343	4.04%
DRIEHAUS CAPITAL MANAGEMENT LLC	3.11M	Dec 31, 25	+688.74K	3.74%
ADAGE CAPITAL PARTNERS GP, L.L.C.	2.78M	Dec 31, 25	-4.04M	3.34%
GOLDMAN SACHS GROUP INC	2.61M	Dec 31, 25	+602.59K	3.14%
MORGAN STANLEY	2.36M	Dec 31, 25	+409.52K	2.84%
Almitas Capital LLC	2.12M	Dec 31, 25	--	2.55%
GREAT POINT PARTNERS LLC	1.75M	Dec 31, 25	+50.00K	2.11%
683 Capital Management, LLC	1.65M	Dec 31, 25	-110.00K	1.98%
EVENTIDE ASSET MANAGEMENT, LLC	1.51M	Dec 31, 25	+648	1.82%
BANK OF AMERICA CORP /DE/	1.34M	Dec 31, 25	+906.49K	1.61%
Logos Global Management LP	950.00K	Dec 31, 25	-500.00K	1.14%
NORTHERN TRUST CORP	937.76K	Dec 31, 25	+115.53K	1.13%
ADAR1 Capital Management, LLC	890.36K	Dec 31, 25	+24.15K	1.07%
BALYASNY ASSET MANAGEMENT L.P.	858.68K	Dec 31, 25	-617.62K	1.03%
Woodline Partners LP	845.41K	Dec 31, 25	+118	1.02%
Nantahala Capital Management, LLC	835.68K	Dec 31, 25	-100.00K	1.01%
Boxer Capital Management, LLC	800.00K	Dec 31, 25	-100.00K	0.96%
StemPoint Capital LP	565.14K	Dec 31, 25	+288.26K	0.68%
Sofinnova Investments, Inc.	527.10K	Dec 31, 25	+527.10K	0.63%
AMERIPRISE FINANCIAL INC	502.37K	Dec 31, 25	+368.86K	0.60%
Rock Springs Capital Management LP	499.76K	Dec 31, 25	--	0.60%
Qube Research & Technologies Ltd	412.87K	Dec 31, 25	+245.77K	0.50%
Cormorant Asset Management, LP	400.00K	Dec 31, 25	-100.00K	0.48%
Parkman Healthcare Partners LLC	381.76K	Dec 31, 25	-197.41K	0.46%
CITADEL ADVISORS LLC	344.97K	Dec 31, 25	+110.30K	0.41%
Point72 Asset Management, L.P.	335.00K	Dec 31, 25	-2.46M	0.40%
ACUTA CAPITAL PARTNERS, LLC	333.26K	Dec 31, 25	--	0.40%
TWO SIGMA ADVISERS, LP	328.40K	Dec 31, 25	+185.40K	0.40%
Alpha Wave Global, LP	317.68K	Dec 31, 25	-9.63K	0.38%
BARCLAYS PLC	295.18K	Dec 31, 25	-118.94K	0.36%
TFG Asset Management GP Ltd	272.83K	Dec 31, 25	+14.59K	0.33%
HighVista Strategies LLC	238.81K	Dec 31, 25	+238.81K	0.29%
WELLINGTON MANAGEMENT GROUP LLP	225.78K	Dec 31, 25	-10.41K	0.27%
SummitTX Capital, L.P.	218.40K	Dec 31, 25	+50.40K	0.26%
Atom Investors LP	139.42K	Dec 31, 25	+139.42K	0.17%
PFM Health Sciences, LP	134.55K	Dec 31, 25	-301.61K	0.16%
PRICE T ROWE ASSOCIATES INC /MD/	107.55K	Dec 31, 25	+7.10K	0.13%
STATE OF WISCONSIN INVESTMENT BOARD	84.14K	Dec 31, 25	+70.27K	0.10%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM	79.09K	Dec 31, 25	+74.76K	0.10%
D. E. Shaw & Co., Inc.	73.22K	Dec 31, 25	+4.35K	0.09%
ALLIANCEBERNSTEIN L.P.	71.50K	Dec 31, 25	--	0.09%
Trexquant Investment LP	48.11K	Dec 31, 25	-174.76K	0.06%
Mariner, LLC	46.34K	Dec 31, 25	-1.69K	0.06%
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.	41.17K	Dec 31, 25	+9.17K	0.05%
Zurcher Kantonalbank (Zurich Cantonalbank)	35.88K	Dec 31, 25	+33.97K	0.04%
Verition Fund Management LLC	29.49K	Dec 31, 25	-34.41K	0.04%
AQR CAPITAL MANAGEMENT LLC	27.85K	Dec 31, 25	-45.79K	0.03%
GUGGENHEIM CAPITAL LLC	25.24K	Dec 31, 25	+344	0.03%
Aquatic Capital Management LLC	24.35K	Dec 31, 25	+24.35K	0.03%
Vanguard Personalized Indexing Management, LLC	20.84K	Dec 31, 25	-261	0.03%
BROWN ADVISORY INC	19.93K	Dec 31, 25	--	0.02%
Rafferty Asset Management, LLC	17.67K	Dec 31, 25	+17.67K	0.02%
Quadrature Capital Ltd	15.46K	Dec 31, 25	-12.82K	0.02%
Quest Partners LLC	7.20K	Dec 31, 25	-6.44K	0.01%
T. Rowe Price Investment Management, Inc.	4.52K	Dec 31, 25	-1.19M	0.01%
SIMPLEX TRADING, LLC	3.73K	Dec 31, 25	+3.73K	0.00%
SRS Capital Advisors, Inc.	2.55K	Dec 31, 25	+306	0.00%
US BANCORP \DE\	2.00K	Dec 31, 25	-2.00K	0.00%
CWM, LLC	1.19K	Dec 31, 25	+7	0.00%
Rockefeller Capital Management L.P.	261	Dec 31, 25	+256	0.00%
JONES FINANCIAL COMPANIES LLLP	30	Dec 31, 25	--	0.00%
Allworth Financial LP	12	Dec 31, 25	--	0.00%
DARK FOREST CAPITAL MANAGEMENT LP	--	Dec 31, 25	-86.80K	--
Ally Bridge Group (NY) LLC	--	Dec 31, 25	-437.39K	--
Longaeva Partners L.P.	--	Dec 31, 25	-200.00K	--
CAPSTONE INVESTMENT ADVISORS, LLC	--	Dec 31, 25	-10.63K	--
Brevan Howard Capital Management LP	--	Dec 31, 25	-56.67K	--
Paradigm Biocapital Advisors LP	--	Dec 31, 25	-1.90M	--
TANG CAPITAL MANAGEMENT LLC	--	Dec 31, 25	-100.00K	--
Global Retirement Partners, LLC	--	Dec 31, 25	-1.00K	--
FRED ALGER MANAGEMENT, LLC	--	Dec 31, 25	-164.04K	--
Maven Securities LTD	--	Dec 31, 25	-70.00K	--
ORBIMED ADVISORS LLC	--	Dec 31, 25	-750.60K	--
Point72 (DIFC) Ltd	5.97K	Sep 30, 25	+5.97K	0.01%
Cubist Systematic Strategies, LLC	5.60K	Sep 30, 25	-117.64K	0.01%
Allostery Investments LP	120.12K	Jun 30, 25	-145.98K	0.14%
Ghost Tree Capital, LLC	325.00K	Sep 30, 24	+325.00K	0.39%
Boxer Capital, LLC	--	Sep 30, 24	-1.50M	--
BlackRock Inc.	2.67M	Jun 30, 24	-1.80M	3.21%
CREDIT SUISSE AG/	36.64K	Mar 31, 24	-1.41K	0.04%
Cipher Capital LP	10.72K	Mar 31, 24	+10.72K	0.01%
Cutler Group LLC / CA	1.00K	Mar 31, 24	+100	0.00%
Point72 Middle East FZE	9.14K	Dec 31, 23	-14.23K	0.01%
Weiss Multi-Strategy Advisers LLC	--	Dec 31, 23	-14.05K	--
PUTNAM INVESTMENTS LLC	--	Dec 31, 23	-46.46K	--
INTERNATIONAL BIOTECHNOLOGY TRUST PLC	295.00K	Sep 30, 23	+270.00K	0.35%
PICTET ASSET MANAGEMENT SA	601.65K	Jun 30, 23	-832.20K	0.72%
Tekla Capital Management LLC	104.01K	Jun 30, 23	+104.01K	0.13%
Kula Investments, LLC	12.51K	Mar 31, 23	+12.51K	0.02%
Jefferies Group LLC	2.79K	Sep 30, 22	+2.79K	0.00%
Amalgamated Financial Corp.	1.76K	Mar 31, 22	+1.76K	0.00%

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Holder

Date

Change

% Held

FMR LLC

16.63M

Mar 31, 26

+112.12K

20.01%

BlackRock, Inc.

8.83M

Mar 31, 26

-225.59K

10.62%

PERCEPTIVE ADVISORS LLC

8.28M

Mar 31, 26

9.97%

TCG Crossover Management, LLC

6.24M

Mar 31, 26

7.51%

COMMODORE CAPITAL LP

5.65M

Mar 31, 26

6.80%

JANUS HENDERSON GROUP PLC

4.99M

Mar 31, 26

+520.20K

6.00%

Saturn V Capital Management LLC

4.35M

Mar 31, 26

-146.60K

5.23%

ADAGE CAPITAL PARTNERS GP, L.L.C.

3.56M

Mar 31, 26

+783.71K

4.28%

First Light Asset Management, LLC

3.19M

Mar 31, 26

-164.89K

3.84%

DRIEHAUS CAPITAL MANAGEMENT LLC

2.99M

Mar 31, 26

-122.36K

3.59%

GOLDMAN SACHS GROUP INC

2.63M

Mar 31, 26

+12.77K

3.16%

STATE STREET CORP

2.36M

Mar 31, 26

+293.28K

2.84%

FRANKLIN RESOURCES INC

2.26M

Mar 31, 26

+1.06M

2.72%

GEODE CAPITAL MANAGEMENT, LLC

2.21M

Mar 31, 26

+45.40K

2.66%

MORGAN STANLEY

2.18M

Mar 31, 26

-184.28K

2.62%

Almitas Capital LLC

2.12M

Mar 31, 26

2.55%

GREAT POINT PARTNERS LLC

1.75M

Mar 31, 26

2.11%

683 Capital Management, LLC

1.53M

Mar 31, 26

-120.00K

1.84%

EVENTIDE ASSET MANAGEMENT, LLC

1.51M

Mar 31, 26

+810

1.82%

DEUTSCHE BANK AG\

1.27M

Mar 31, 26

-65.45K

1.53%

Siren, L.L.C.

1.23M

Mar 31, 26

+1.23M

1.48%

BALYASNY ASSET MANAGEMENT L.P.

1.11M

Mar 31, 26

+248.59K

1.33%

BARCLAYS PLC

971.85K

Mar 31, 26

+676.68K

1.17%

DIMENSIONAL FUND ADVISORS LP

903.19K

Mar 31, 26

+131.94K

1.09%

Connor, Clark & Lunn Investment Management Ltd.

868.33K

Mar 31, 26

-135.70K

1.04%

Woodline Partners LP

845.80K

Mar 31, 26

+392

1.02%

Boxer Capital Management, LLC

800.00K

Mar 31, 26

0.96%

NORTHERN TRUST CORP

779.91K

Mar 31, 26

-157.86K

0.94%

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

716.23K

Mar 31, 26

+3.23K

0.86%

Qube Research & Technologies Ltd

702.24K

Mar 31, 26

+289.36K

0.84%

Logos Global Management LP

700.00K

Mar 31, 26

-250.00K

0.84%

StemPoint Capital LP

669.68K

Mar 31, 26

+104.55K

0.81%

Parkman Healthcare Partners LLC

621.46K

Mar 31, 26

+239.70K

0.75%

JUPITER ASSET MANAGEMENT LTD

592.65K

Mar 31, 26

+577.08K

0.71%

VANGUARD FIDUCIARY TRUST CO

586.15K

Mar 31, 26

+586.15K

0.71%

Nantahala Capital Management, LLC

535.68K

Mar 31, 26

-300.00K

0.64%

Rock Springs Capital Management LP

499.76K

Mar 31, 26

0.60%

CITADEL ADVISORS LLC

411.53K

Mar 31, 26

+66.56K

0.50%

FEDERATED HERMES, INC.

363.55K

Mar 31, 26

-93.87K

0.44%

HighVista Strategies LLC

352.08K

Mar 31, 26

+113.27K

0.42%

Cormorant Asset Management, LP

350.00K

Mar 31, 26

-50.00K

0.42%

UBS Group AG

324.32K

Mar 31, 26

-219.00K

0.39%

TFG Asset Management GP Ltd

317.88K

Mar 31, 26

+45.05K

0.38%

iA Global Asset Management Inc.

304.79K

Mar 31, 26

+304.79K

0.37%

Nuveen, LLC

264.90K

Mar 31, 26

-19.05K

0.32%

Bank of New York Mellon Corp

251.10K

Mar 31, 26

+33.76K

0.30%

WELLINGTON MANAGEMENT GROUP LLP

241.55K

Mar 31, 26

+15.77K

0.29%

SummitTX Capital, L.P.

227.01K

Mar 31, 26

+8.61K

0.27%

Aldebaran Capital, LLC

197.89K

Mar 31, 26

-616

0.24%

Invesco Ltd.

171.62K

Mar 31, 26

-4.29K

0.21%

TWO SIGMA INVESTMENTS, LP

161.94K

Mar 31, 26

-182.46K

0.19%

JPMORGAN CHASE & CO

159.66K

Mar 31, 26

+93.12K

0.19%

UBS ASSET MANAGEMENT AMERICAS INC

157.09K

Mar 31, 26

+58.25K

0.19%

ACUTA CAPITAL PARTNERS, LLC

151.07K

Mar 31, 26

-182.19K

0.18%

PFM Health Sciences, LP

145.28K

Mar 31, 26

+10.73K

0.17%

Alpha Wave Global, LP

142.34K

Mar 31, 26

-175.34K

0.17%

Swiss National Bank

130.30K

Mar 31, 26

-31.40K

0.16%

PRICE T ROWE ASSOCIATES INC /MD/

121.44K

Mar 31, 26

+13.89K

0.15%

Squarepoint Ops LLC

114.88K

Mar 31, 26

+38.31K

0.14%

RHUMBLINE ADVISERS

108.47K

Mar 31, 26

+9.19K

0.13%

Point72 Asset Management, L.P.

106.53K

Mar 31, 26

-228.47K

0.13%

ALPS ADVISORS INC

89.98K

Mar 31, 26

-189

0.11%

SEI INVESTMENTS CO

85.28K

Mar 31, 26

+32.42K

0.10%

ALLIANCEBERNSTEIN L.P.

80.80K

Mar 31, 26

+9.30K

0.10%

Schonfeld Strategic Advisors LLC

77.79K

Mar 31, 26

+56.74K

0.09%

WELLS FARGO & COMPANY/MN

75.08K

Mar 31, 26

-71.23K

0.09%

D. E. Shaw & Co., Inc.

74.23K

Mar 31, 26

+1.01K

0.09%

STATE OF WISCONSIN INVESTMENT BOARD

72.06K

Mar 31, 26

-12.08K

0.09%

Walleye Capital LLC

61.71K

Mar 31, 26

+55.97K

0.07%

Russell Investments Group, Ltd.

59.35K

Mar 31, 26

-6.09K

0.07%

Legal & General Group Plc

55.77K

Mar 31, 26

-16.84K

0.07%

Campbell & CO Investment Adviser LLC

54.42K

Mar 31, 26

-24.34K

0.07%

EAM Investors, LLC

53.26K

Mar 31, 26

0.06%

MetLife Investment Management, LLC

51.59K

Mar 31, 26

+1.93K

0.06%

Maven Securities LTD

50.00K

Mar 31, 26

+50.00K

0.06%

Numerai GP LLC

48.55K

Mar 31, 26

-64.09K

0.06%

Vanguard Global Advisers, LLC

47.85K

Mar 31, 26

+47.85K

0.06%

VANGUARD ASSET MANAGEMENT, Ltd

43.28K

Mar 31, 26

+43.28K

0.05%

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

42.55K

Mar 31, 26

+1.39K

0.05%

Zurcher Kantonalbank (Zurich Cantonalbank)

40.79K

Mar 31, 26

+4.91K

0.05%

SUSQUEHANNA INTERNATIONAL GROUP, LLP

39.80K

Mar 31, 26

-29.09K

0.05%

MANUFACTURERS LIFE INSURANCE COMPANY, THE

38.78K

Mar 31, 26

+11.79K

0.05%

Optimize Financial Inc

32.00K

Mar 31, 26

+32.00K

0.04%

CITIGROUP INC

31.78K

Mar 31, 26

-6.25K

0.04%

TUDOR INVESTMENT CORP ET AL

31.33K

Mar 31, 26

+8.93K

0.04%

AQR CAPITAL MANAGEMENT LLC

29.09K

Mar 31, 26

+1.24K

0.03%

Integrated Quantitative Investments LLC

27.23K

Mar 31, 26

0.03%

GUGGENHEIM CAPITAL LLC

25.51K

Mar 31, 26

+270

0.03%

INTECH INVESTMENT MANAGEMENT LLC

24.92K

Mar 31, 26

-7.08K

0.03%

Vanguard Personalized Indexing Management, LLC

24.07K

Mar 31, 26

+3.23K

0.03%

Police & Firemen's Retirement System of New Jersey

23.75K

Mar 31, 26

0.03%

State of New Jersey Common Pension Fund D

22.52K

Mar 31, 26

+22.52K

0.03%

NEW YORK STATE COMMON RETIREMENT FUND

21.90K

Mar 31, 26

0.03%

PARSONS CAPITAL MANAGEMENT INC/RI

21.64K

Mar 31, 26

0.03%

BNP PARIBAS ARBITRAGE, SNC

21.14K

Mar 31, 26

-4.06K

0.03%

Virtus Investment Advisers, Inc.

20.82K

Mar 31, 26

+508

0.03%

Premier Path Wealth Partners, LLC

20.27K

Mar 31, 26

0.02%

BROWN ADVISORY INC

19.93K

Mar 31, 26

0.02%

Headlands Technologies LLC

19.81K

Mar 31, 26

-10.73K

0.02%

China Universal Asset Management Co., Ltd.

19.49K

Mar 31, 26

+1.59K

0.02%

ProShare Advisors LLC

18.15K

Mar 31, 26

-2.91K

0.02%

Arizona State Retirement System

18.10K

Mar 31, 26

-4.82K

0.02%

Creative Planning

17.88K

Mar 31, 26

+17.88K

0.02%

Vanguard Investments Australia, Ltd.

17.71K

Mar 31, 26

+17.71K

0.02%

KLP KAPITALFORVALTNING AS

17.40K

Mar 31, 26

0.02%

PROFUND ADVISORS LLC

17.15K

Mar 31, 26

-3.44K

0.02%

VOYA INVESTMENT MANAGEMENT LLC

15.23K

Mar 31, 26

-20

0.02%

PRUDENTIAL FINANCIAL INC

14.12K

Mar 31, 26

+14.12K

0.02%

Verition Fund Management LLC

13.26K

Mar 31, 26

-16.22K

0.02%

ROYAL BANK OF CANADA

12.38K

Mar 31, 26

-3.26K

0.01%

LANDSCAPE CAPITAL MANAGEMENT, L.L.C.

12.23K

Mar 31, 26

0.01%

HSBC HOLDINGS PLC

11.41K

Mar 31, 26

+11.41K

0.01%

Pictet Asset Management Holding SA

10.77K

Mar 31, 26

+10.77K

0.01%

VICTORY CAPITAL MANAGEMENT INC

10.64K

Mar 31, 26

+92

0.01%

GREAT LAKES ADVISORS, LLC

10.38K

Mar 31, 26

+10.38K

0.01%

Valeo Financial Advisors, LLC

10.00K

Mar 31, 26

-5.00K

0.01%

MAI Capital Management

9.01K

Mar 31, 26

+9.01K

0.01%

ACT CAPITAL MANAGEMENT, LLC

9.00K

Mar 31, 26

0.01%

Tower Research Capital LLC (TRC)

7.91K

Mar 31, 26

-182

0.01%

Ameritas Investment Partners, Inc.

7.20K

Mar 31, 26

0.01%

Mirae Asset Global Investments Co., Ltd.

5.73K

Mar 31, 26

+391

0.01%

STRS OHIO

3.40K

Mar 31, 26

0.00%

GF FUND MANAGEMENT CO. LTD.

2.46K

Mar 31, 26

+297

0.00%

US BANCORP \DE\

2.06K

Mar 31, 26

+63

0.00%

State of Wyoming

1.88K

Mar 31, 26

+502

0.00%

KBC Group NV

1.86K

Mar 31, 26

+1.86K

0.00%

LORING WOLCOTT & COOLIDGE FIDUCIARY ADVISORS LLP/MA

1.80K

Mar 31, 26

0.00%

SRS Capital Advisors, Inc.

1.49K

Mar 31, 26

-1.06K

0.00%

BNP Paribas Asset Management Holding S.A.

1.42K

Mar 31, 26

+103

0.00%

Rockefeller Capital Management L.P.

1.27K

Mar 31, 26

+1.01K

0.00%

CWM, LLC

1.26K

Mar 31, 26

+70

0.00%

Sterling Capital Management LLC

1.14K

Mar 31, 26

-490

0.00%

Steward Partners Investment Advisory, LLC

1.00K

Mar 31, 26

-500

0.00%

NISA INVESTMENT ADVISORS, LLC

922

Mar 31, 26

0.00%

Westfuller Advisors, LLC

819

Mar 31, 26

0.00%

FIFTH THIRD BANCORP

755

Mar 31, 26

+755

0.00%

MEEDER ASSET MANAGEMENT INC

661

Mar 31, 26

-1.44K

0.00%

Dunhill Financial, LLC

600

Mar 31, 26

0.00%

ADVISOR GROUP HOLDINGS, INC.

528

Mar 31, 26

+279

0.00%

GAMMA Investing LLC

417

Mar 31, 26

+150

0.00%

J.Safra Asset Management Corp

377

Mar 31, 26

+254

0.00%

LOS ANGELES CAPITAL MANAGEMENT LLC

325

Mar 31, 26

-527

0.00%

EverSource Wealth Advisors, LLC

285

Mar 31, 26

+260

0.00%

PNC FINANCIAL SERVICES GROUP, INC.

283

Mar 31, 26

-155

0.00%

MASSMUTUAL TRUST CO FSB/ADV

282

Mar 31, 26

+129

0.00%

Physician Wealth Advisors, Inc.

274

Mar 31, 26

0.00%

JONES FINANCIAL COMPANIES LLLP

270

Mar 31, 26

+240

0.00%

SIGNATUREFD, LLC

254

Mar 31, 26

+254

0.00%

Larson Financial Group LLC

201

Mar 31, 26

+160

0.00%

EASTERN BANK

200

Mar 31, 26

+200

0.00%

HARBOUR INVESTMENTS, INC.

Mar 31, 26

0.00%

Stone House Investment Management, LLC

Mar 31, 26

+73

0.00%

ROTHSCHILD INVESTMENT LLC

Mar 31, 26

+55

0.00%

SALEM INVESTMENT COUNSELORS INC

Mar 31, 26

+55

0.00%

Allworth Financial LP

Mar 31, 26

+28

0.00%

Caitong International Asset Management Co., Ltd

Mar 31, 26

-3.82K

0.00%

Farther Finance Advisors, LLC

Mar 31, 26

0.00%

Ameritas Advisory Services, LLC

Mar 31, 26

0.00%

SBI Securities Co., Ltd.

Mar 31, 26

0.00%

EVOLUTION WEALTH MANAGEMENT INC.

Mar 31, 26

-165

FINANCIAL CONSULATE, INC

Mar 31, 26

-25

VOLORIDGE INVESTMENT MANAGEMENT, LLC

Mar 31, 26

-153.36K

Rafferty Asset Management, LLC

Mar 31, 26

-17.67K

Persistent Asset Partners Ltd

Mar 31, 26

-31.15K

Daiwa Securities Group Inc.

Mar 31, 26

-266

AMALGAMATED BANK

Mar 31, 26

-2.79K

Walleye Trading LLC

Mar 31, 26

-2.83K

BANK OF MONTREAL /CAN/

Mar 31, 26

-138.53K

Sofinnova Investments, Inc.

Mar 31, 26

-527.10K

Kennondale Capital Management LLC

Mar 31, 26

-53.42K

MILLENNIUM MANAGEMENT LLC

Mar 31, 26

-46.45K

Mariner, LLC

Mar 31, 26

-46.34K

Atom Investors LP

Mar 31, 26

-139.42K

AMERIPRISE FINANCIAL INC

Mar 31, 26

-502.37K

TEACHER RETIREMENT SYSTEM OF TEXAS

Mar 31, 26

-12.17K

Engineers Gate Manager LP

Mar 31, 26

-18.36K

ACADIAN ASSET MANAGEMENT LLC

Mar 31, 26

-254.33K

GSA CAPITAL PARTNERS LLP

Mar 31, 26

-36.76K

SILVERARC CAPITAL MANAGEMENT, LLC

Mar 31, 26

-506.24K

Patient Square Capital LP

Mar 31, 26

-350.00K

FOX RUN MANAGEMENT, L.L.C.

Mar 31, 26

-35.41K

EntryPoint Capital, LLC

Mar 31, 26

-10.49K

RENAISSANCE TECHNOLOGIES LLC

Mar 31, 26

-192.50K

Quadrature Capital Ltd

Mar 31, 26

-15.46K

SG Americas Securities, LLC

Mar 31, 26

-20.85K

IFP Advisors, Inc

Mar 31, 26

-1

SIMPLEX TRADING, LLC

Mar 31, 26

-3.73K

JANE STREET GROUP, LLC

Mar 31, 26

-263.24K

Aquatic Capital Management LLC

Mar 31, 26

-24.35K

T. Rowe Price Investment Management, Inc.

Mar 31, 26

-4.52K

XTX Topco Ltd

Mar 31, 26

-189.67K

Trexquant Investment LP

Mar 31, 26

-48.11K

FMR LLC

16.52M

Dec 31, 25

+5.14M

19.87%

PERCEPTIVE ADVISORS LLC

8.28M

Dec 31, 25

-667.48K

9.97%

TCG Crossover Management, LLC

6.24M

Dec 31, 25

7.51%

VANGUARD GROUP INC

5.80M

Dec 31, 25

+531.16K

6.98%

COMMODORE CAPITAL LP

5.65M

Dec 31, 25

+1.57M

6.80%

JANUS HENDERSON GROUP PLC

4.47M

Dec 31, 25

+1.93M

5.37%

First Light Asset Management, LLC

3.36M

Dec 31, 25

-343

4.04%

DRIEHAUS CAPITAL MANAGEMENT LLC

3.11M

Dec 31, 25

+688.74K

3.74%

ADAGE CAPITAL PARTNERS GP, L.L.C.

2.78M

Dec 31, 25

-4.04M

3.34%

GOLDMAN SACHS GROUP INC

2.61M

Dec 31, 25

+602.59K

3.14%

MORGAN STANLEY

2.36M

Dec 31, 25

+409.52K

2.84%

Almitas Capital LLC

2.12M

Dec 31, 25

2.55%

GREAT POINT PARTNERS LLC

1.75M

Dec 31, 25

+50.00K

2.11%

683 Capital Management, LLC

1.65M

Dec 31, 25

-110.00K

1.98%

EVENTIDE ASSET MANAGEMENT, LLC

1.51M

Dec 31, 25

+648

1.82%

BANK OF AMERICA CORP /DE/

1.34M

Dec 31, 25

+906.49K

1.61%

Logos Global Management LP

950.00K

Dec 31, 25

-500.00K

1.14%

NORTHERN TRUST CORP

937.76K

Dec 31, 25

+115.53K

1.13%

ADAR1 Capital Management, LLC

890.36K

Dec 31, 25

+24.15K

1.07%

BALYASNY ASSET MANAGEMENT L.P.

858.68K

Dec 31, 25

-617.62K

1.03%

Woodline Partners LP

845.41K

Dec 31, 25

+118

1.02%

Nantahala Capital Management, LLC

835.68K

Dec 31, 25

-100.00K

1.01%

Boxer Capital Management, LLC

800.00K

Dec 31, 25

-100.00K

0.96%

StemPoint Capital LP

565.14K

Dec 31, 25

+288.26K

0.68%

Sofinnova Investments, Inc.

527.10K

Dec 31, 25

+527.10K

0.63%

AMERIPRISE FINANCIAL INC

502.37K

Dec 31, 25

+368.86K

0.60%

Rock Springs Capital Management LP

499.76K

Dec 31, 25

0.60%

Qube Research & Technologies Ltd

412.87K

Dec 31, 25

+245.77K

0.50%

Cormorant Asset Management, LP

400.00K

Dec 31, 25

-100.00K

0.48%

Parkman Healthcare Partners LLC

381.76K

Dec 31, 25

-197.41K

0.46%

CITADEL ADVISORS LLC

344.97K

Dec 31, 25

+110.30K

0.41%

Point72 Asset Management, L.P.

335.00K

Dec 31, 25

-2.46M

0.40%

ACUTA CAPITAL PARTNERS, LLC

333.26K

Dec 31, 25

0.40%

TWO SIGMA ADVISERS, LP

328.40K

Dec 31, 25

+185.40K

0.40%

Alpha Wave Global, LP

317.68K

Dec 31, 25

-9.63K

0.38%

BARCLAYS PLC

295.18K

Dec 31, 25

-118.94K

0.36%

TFG Asset Management GP Ltd

272.83K

Dec 31, 25

+14.59K

0.33%

HighVista Strategies LLC

238.81K

Dec 31, 25

+238.81K

0.29%

WELLINGTON MANAGEMENT GROUP LLP

225.78K

Dec 31, 25

-10.41K

0.27%

SummitTX Capital, L.P.

218.40K

Dec 31, 25

+50.40K

0.26%

Atom Investors LP

139.42K

Dec 31, 25

+139.42K

0.17%

PFM Health Sciences, LP

134.55K

Dec 31, 25

-301.61K

0.16%

PRICE T ROWE ASSOCIATES INC /MD/

107.55K

Dec 31, 25

+7.10K

0.13%

STATE OF WISCONSIN INVESTMENT BOARD

84.14K

Dec 31, 25

+70.27K

0.10%

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM

79.09K

Dec 31, 25

+74.76K

0.10%

D. E. Shaw & Co., Inc.

73.22K

Dec 31, 25

+4.35K

0.09%

ALLIANCEBERNSTEIN L.P.

71.50K

Dec 31, 25

0.09%

Trexquant Investment LP

48.11K

Dec 31, 25

-174.76K

0.06%

Mariner, LLC

46.34K

Dec 31, 25

-1.69K

0.06%

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

41.17K

Dec 31, 25

+9.17K

0.05%

Zurcher Kantonalbank (Zurich Cantonalbank)

35.88K

Dec 31, 25

+33.97K

0.04%

Verition Fund Management LLC

29.49K

Dec 31, 25

-34.41K

0.04%

AQR CAPITAL MANAGEMENT LLC

27.85K

Dec 31, 25

-45.79K

0.03%

GUGGENHEIM CAPITAL LLC

25.24K

Dec 31, 25

+344

0.03%

Aquatic Capital Management LLC

24.35K

Dec 31, 25

+24.35K

0.03%

Vanguard Personalized Indexing Management, LLC

20.84K

Dec 31, 25

-261

0.03%

BROWN ADVISORY INC

19.93K

Dec 31, 25

0.02%

Rafferty Asset Management, LLC

17.67K

Dec 31, 25

+17.67K

0.02%

Quadrature Capital Ltd

15.46K

Dec 31, 25

-12.82K

0.02%

Quest Partners LLC

7.20K

Dec 31, 25

-6.44K

0.01%

T. Rowe Price Investment Management, Inc.

4.52K

Dec 31, 25

-1.19M

0.01%

SIMPLEX TRADING, LLC

3.73K

Dec 31, 25

+3.73K

0.00%

SRS Capital Advisors, Inc.

2.55K

Dec 31, 25

+306

0.00%

US BANCORP \DE\

2.00K

Dec 31, 25

-2.00K

0.00%

CWM, LLC

1.19K

Dec 31, 25

0.00%

Rockefeller Capital Management L.P.

261

Dec 31, 25

+256

0.00%

JONES FINANCIAL COMPANIES LLLP

Dec 31, 25

0.00%

Allworth Financial LP

Dec 31, 25

0.00%

DARK FOREST CAPITAL MANAGEMENT LP

Dec 31, 25

-86.80K

Ally Bridge Group (NY) LLC

Dec 31, 25

-437.39K

Longaeva Partners L.P.

Dec 31, 25

-200.00K

CAPSTONE INVESTMENT ADVISORS, LLC

Dec 31, 25

-10.63K

Brevan Howard Capital Management LP

Dec 31, 25

-56.67K

Paradigm Biocapital Advisors LP

Dec 31, 25

-1.90M

TANG CAPITAL MANAGEMENT LLC

Dec 31, 25

-100.00K

Global Retirement Partners, LLC

Dec 31, 25

-1.00K

FRED ALGER MANAGEMENT, LLC

Dec 31, 25

-164.04K

Maven Securities LTD

Dec 31, 25

-70.00K

ORBIMED ADVISORS LLC

Dec 31, 25

-750.60K

Point72 (DIFC) Ltd

5.97K

Sep 30, 25

+5.97K

0.01%

Cubist Systematic Strategies, LLC

5.60K

Sep 30, 25

-117.64K

0.01%

Allostery Investments LP

120.12K

Jun 30, 25

-145.98K

0.14%

Ghost Tree Capital, LLC

325.00K

Sep 30, 24

+325.00K

0.39%

Boxer Capital, LLC

Sep 30, 24

-1.50M

BlackRock Inc.

2.67M

Jun 30, 24

-1.80M

3.21%

CREDIT SUISSE AG/

36.64K

Mar 31, 24

-1.41K

0.04%

Cipher Capital LP

10.72K

Mar 31, 24

+10.72K

0.01%

Cutler Group LLC / CA

1.00K

Mar 31, 24

+100

0.00%

Point72 Middle East FZE

9.14K

Dec 31, 23

-14.23K

0.01%

Weiss Multi-Strategy Advisers LLC

Dec 31, 23

-14.05K

PUTNAM INVESTMENTS LLC

Dec 31, 23

-46.46K

INTERNATIONAL BIOTECHNOLOGY TRUST PLC

295.00K

Sep 30, 23

+270.00K

0.35%

PICTET ASSET MANAGEMENT SA

601.65K

Jun 30, 23

-832.20K

0.72%

Tekla Capital Management LLC

104.01K

Jun 30, 23

+104.01K

0.13%

Kula Investments, LLC

12.51K

Mar 31, 23

+12.51K

0.02%

Jefferies Group LLC

2.79K

Sep 30, 22

+2.79K

0.00%

Amalgamated Financial Corp.

1.76K

Mar 31, 22

+1.76K

0.00%