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Latest holdings as of Funds file quarterly, up to 45 days after quarter end; this page refreshes weeklyAbout this data
| Holder | Shares | Date | Change | % Held |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 13.72M | Jun 30, 26 | +2.82M | 17.48% |
| BAKER BROS. ADVISORS LP | 10.12M | Jun 30, 26 | -- | 12.90% |
| RA CAPITAL MANAGEMENT, L.P. | 6.48M | Jun 30, 26 | +6.48M | 8.25% |
| Soleus Capital Management, L.P. | 3.38M | Jun 30, 26 | +3.38M | 4.30% |
| Kynam Capital Management, LP | 2.42M | Jun 30, 26 | +822.54K | 3.08% |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.01M | Jun 30, 26 | +779.04K | 2.56% |
| BlackRock, Inc. | 1.80M | Jun 30, 26 | +1.48M | 2.29% |
| SPHERA FUNDS MANAGEMENT LTD. | 1.02M | Jun 30, 26 | +461.49K | 1.30% |
| TWO SIGMA INVESTMENTS, LP | 993.37K | Jun 30, 26 | +69.74K | 1.27% |
| ADAR1 Capital Management, LLC | 900.90K | Jun 30, 26 | +748.08K | 1.15% |
| MILLENNIUM MANAGEMENT LLC | 844.99K | Jun 30, 26 | +462.26K | 1.08% |
| GEODE CAPITAL MANAGEMENT, LLC | 841.86K | Jun 30, 26 | +539.40K | 1.07% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 766.10K | Jun 30, 26 | +766.10K | 0.98% |
| ACADIAN ASSET MANAGEMENT LLC | 611.36K | Jun 30, 26 | +99.84K | 0.78% |
| MORGAN STANLEY | 503.86K | Jun 30, 26 | +181.70K | 0.64% |
| STATE STREET CORP | 428.79K | Jun 30, 26 | +290.56K | 0.55% |
| UBS Group AG | 318.80K | Jun 30, 26 | +254.29K | 0.41% |
| VANGUARD FIDUCIARY TRUST CO | 284.89K | Jun 30, 26 | +127.51K | 0.36% |
| RENAISSANCE TECHNOLOGIES LLC | 281.20K | Jun 30, 26 | +6.00K | 0.36% |
| NORTHERN TRUST CORP | 240.60K | Jun 30, 26 | +190.48K | 0.31% |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 193.92K | Jun 30, 26 | +193.92K | 0.25% |
| MARSHALL WACE, LLP | 190.69K | Jun 30, 26 | -168.21K | 0.24% |
| Connor, Clark & Lunn Investment Management Ltd. | 125.61K | Jun 30, 26 | +16.52K | 0.16% |
| GOLDMAN SACHS GROUP INC | 120.83K | Jun 30, 26 | -115.64K | 0.15% |
| Hillsdale Investment Management Inc. | 81.40K | Jun 30, 26 | +81.40K | 0.10% |
| Bank of New York Mellon Corp | 68.19K | Jun 30, 26 | +68.19K | 0.09% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 67.62K | Jun 30, 26 | +67.62K | 0.09% |
| Sixth Street Partners Management Company, L.P. | 67.62K | Jun 30, 26 | +67.62K | 0.09% |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 64.50K | Jun 30, 26 | +11.00K | 0.08% |
| Squarepoint Ops LLC | 59.54K | Jun 30, 26 | +59.54K | 0.08% |
| PANAGORA ASSET MANAGEMENT INC | 47.57K | Jun 30, 26 | +47.57K | 0.06% |
| Mariner, LLC | 45.26K | Jun 30, 26 | +45.26K | 0.06% |
| Nuveen, LLC | 37.02K | Jun 30, 26 | +37.02K | 0.05% |
| DIMENSIONAL FUND ADVISORS LP | 35.21K | Jun 30, 26 | -- | 0.04% |
| Invesco Ltd. | 34.74K | Jun 30, 26 | +34.74K | 0.04% |
| Cerity Partners LLC | 32.88K | Jun 30, 26 | -- | 0.04% |
| State of Wyoming | 32.86K | Jun 30, 26 | +32.86K | 0.04% |
| Graham Capital Management, L.P. | 29.77K | Jun 30, 26 | +18.43K | 0.04% |
| DEUTSCHE BANK AG\ | 27.82K | Jun 30, 26 | +27.82K | 0.04% |
| WELLS FARGO & COMPANY/MN | 25.32K | Jun 30, 26 | +25.32K | 0.03% |
| BANK OF AMERICA CORP /DE/ | 23.88K | Jun 30, 26 | -32.65K | 0.03% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 22.76K | Jun 30, 26 | +22.76K | 0.03% |
| CITADEL ADVISORS LLC | 22.55K | Jun 30, 26 | -101.82K | 0.03% |
| RHUMBLINE ADVISERS | 22.07K | Jun 30, 26 | +22.07K | 0.03% |
| Vanguard Global Advisers, LLC | 16.21K | Jun 30, 26 | +11.57K | 0.02% |
| ExodusPoint Capital Management, LP | 15.47K | Jun 30, 26 | +15.47K | 0.02% |
| BARCLAYS PLC | 14.53K | Jun 30, 26 | +5.93K | 0.02% |
| NEW YORK STATE COMMON RETIREMENT FUND | 14.20K | Jun 30, 26 | +14.20K | 0.02% |
| HSBC HOLDINGS PLC | 13.65K | Jun 30, 26 | -- | 0.02% |
| JPMORGAN CHASE & CO | 13.54K | Jun 30, 26 | +13.48K | 0.02% |
| MANGROVE PARTNERS | 13.35K | Jun 30, 26 | +13.35K | 0.02% |
| Qube Research & Technologies Ltd | 13.11K | Jun 30, 26 | -3.31K | 0.02% |
| CITIGROUP INC | 13.03K | Jun 30, 26 | +13.03K | 0.02% |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 12.78K | Jun 30, 26 | +12.78K | 0.02% |
| GSA CAPITAL PARTNERS LLP | 12.67K | Jun 30, 26 | +12.67K | 0.02% |
| Spark Investment Management LLC | 10.60K | Jun 30, 26 | +10.60K | 0.01% |
| ALLIANCEBERNSTEIN L.P. | 10.53K | Jun 30, 26 | +10.53K | 0.01% |
| Police & Firemen's Retirement System of New Jersey | 10.49K | Jun 30, 26 | +10.49K | 0.01% |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 6.43K | Jun 30, 26 | +6.43K | 0.01% |
| FMR LLC | 5.63K | Jun 30, 26 | -380 | 0.01% |
| STRS OHIO | 5.50K | Jun 30, 26 | +5.50K | 0.01% |
| BNP PARIBAS ARBITRAGE, SNC | 4.10K | Jun 30, 26 | +4.01K | 0.01% |
| GROUP ONE TRADING, L.P. | 3.91K | Jun 30, 26 | -- | 0.00% |
| Legal & General Group Plc | 2.70K | Jun 30, 26 | +2.70K | 0.00% |
| ROYAL BANK OF CANADA | 2.66K | Jun 30, 26 | +327 | 0.00% |
| Ameritas Investment Partners, Inc. | 2.52K | Jun 30, 26 | +2.52K | 0.00% |
| Tower Research Capital LLC (TRC) | 2.38K | Jun 30, 26 | +2.38K | 0.00% |
| Russell Investments Group, Ltd. | 2.22K | Jun 30, 26 | +2.22K | 0.00% |
| NISA INVESTMENT ADVISORS, LLC | 1.63K | Jun 30, 26 | -- | 0.00% |
| PNC FINANCIAL SERVICES GROUP, INC. | 1.17K | Jun 30, 26 | -- | 0.00% |
| Quarry LP | 755 | Jun 30, 26 | +755 | 0.00% |
| Fortitude Family Office, LLC | 230 | Jun 30, 26 | -- | 0.00% |
| Sterling Capital Management LLC | 97 | Jun 30, 26 | +97 | 0.00% |
| SBI Securities Co., Ltd. | 22 | Jun 30, 26 | -2.62K | 0.00% |
| Caitong International Asset Management Co., Ltd | 18 | Jun 30, 26 | +18 | 0.00% |
| MERCER GLOBAL ADVISORS INC /ADV | 5 | Jun 30, 26 | +5 | 0.00% |
| Optiver Holding B.V. | 4 | Jun 30, 26 | -16 | 0.00% |
| PRUDENTIAL FINANCIAL INC | -- | Jun 30, 26 | -17.42K | -- |
| JANE STREET GROUP, LLC | -- | Jun 30, 26 | -192.96K | -- |
| Point72 Asset Management, L.P. | -- | Jun 30, 26 | -16.33K | -- |
| CALDWELL SUTTER CAPITAL, INC. | -- | Jun 30, 26 | -1.00K | -- |
| HRT FINANCIAL LP | -- | Jun 30, 26 | -58.70K | -- |
| Colony Group, LLC | -- | Jun 30, 26 | -50.01K | -- |
| OMERS ADMINISTRATION Corp | -- | Jun 30, 26 | -32.70K | -- |
| AMERICAN CENTURY COMPANIES INC | -- | Jun 30, 26 | -10.29K | -- |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | -- | Jun 30, 26 | -267.79K | -- |
| XTX Topco Ltd | -- | Jun 30, 26 | -57.19K | -- |
| NINE MASTS CAPITAL Ltd | -- | Jun 30, 26 | -11.70K | -- |
| EcoR1 Capital, LLC | -- | Jun 30, 26 | -947.05K | -- |
| Diametric Capital, LP | -- | Jun 30, 26 | -11.98K | -- |
| CWM, LLC | 573 | Mar 31, 26 | -119 | 0.00% |
| VANGUARD GROUP INC | 1.41M | Dec 31, 25 | +421.13K | 1.80% |
| TWO SIGMA ADVISERS, LP | 237.30K | Dec 31, 25 | +14.60K | 0.30% |
| Nuveen Asset Management, LLC | 16.80K | Dec 31, 24 | -- | 0.02% |
| Boxer Capital, LLC | 1.71M | Sep 30, 24 | -860.10K | 2.18% |
| BlackRock Inc. | 1.07M | Jun 30, 24 | -28.56K | 1.36% |
| BREWIN DOLPHIN WEALTH MANAGEMENT LTD | 1.70K | Jun 30, 22 | -- | 0.00% |
| IndexIQ Advisors LLC | 56.75K | Mar 31, 22 | +56.75K | 0.07% |
| Amalgamated Financial Corp. | 1.76K | Mar 31, 22 | +1.76K | 0.00% |
